S Guglielmetti

Summary

Affiliation: University of Milan
Country: Italy

Publications

  1. ncbi request reprint Molecular characterization of Bifidobacterium longum biovar longum NAL8 plasmids and construction of a novel replicon screening system
    Simone Guglielmetti
    Department of Food Science and Microbiology, Industrial Microbiology Section, University of Milan, Via Celoria 2, 20133 Milan, Italy
    Appl Microbiol Biotechnol 74:1053-61. 2007
  2. ncbi request reprint TgaA, a VirB1-Like Component Belonging to a Putative Type IV Secretion System of Bifidobacterium bifidum MIMBb75
    Simone Guglielmetti
    Department of Food Environmental and Nutritional Sciences, Universita degli Studi di Milano, Milan, Italy
    Appl Environ Microbiol 80:5161-9. 2014
  3. ncbi request reprint Murein Lytic Enzyme TgaA of Bifidobacterium bifidum MIMBb75 Modulates Dendritic Cell Maturation through Its Cysteine- and Histidine-Dependent Amidohydrolase/Peptidase (CHAP) Amidase Domain
    Simone Guglielmetti
    Department of Food Environmental and Nutritional Sciences, Universita degli Studi di Milano, Milan, Italy
    Appl Environ Microbiol 80:5170-7. 2014
  4. pmc Health-Promoting Properties of Lactobacillus helveticus
    Valentina Taverniti
    Division of Food Microbiology and Bioprocesses, Department of Food Environmental and Nutritional Sciences, Università degli Studi di Milano Milan, Italy
    Front Microbiol 3:392. 2012
  5. doi request reprint Differential modulation of human intestinal bifidobacterium populations after consumption of a wild blueberry (Vaccinium angustifolium) drink
    Simone Guglielmetti
    Department of Food, Environmental and Nutritional Sciences DeFENS, Division of Food Microbiology and Bioprocessing, Universita degli Studi di Milano, Via Celoria 2, 20133 Milano, Italy
    J Agric Food Chem 61:8134-40. 2013
  6. doi request reprint Luteibacter rhizovicinus MIMR1 promotes root development in barley (Hordeum vulgare L.) under laboratory conditions
    Simone Guglielmetti
    Division of Food Microbiology and Bioprocessing, Department of Food, Environmental and Nutritional Sciences DeFENS, Universita degli Studi di Milano, Via Celoria 2, 20133, Milan, Italy
    World J Microbiol Biotechnol 29:2025-32. 2013
  7. pmc Biotransformation strategy to reduce allergens in propolis
    Claudio Gardana
    Division of Nutrition, Universita degli Studi di Milano, Milan, Italy
    Appl Environ Microbiol 78:4654-8. 2012
  8. pmc In vitro functional and immunomodulatory properties of the Lactobacillus helveticus MIMLh5-Streptococcus salivarius ST3 association that are relevant to the development of a pharyngeal probiotic product
    Valentina Taverniti
    Department of Food Science and Microbiology, Universita degli Studi di Milano, Milan, Italy
    Appl Environ Microbiol 78:4209-16. 2012
  9. ncbi request reprint Study of the adhesion of Bifidobacterium bifidum MIMBb75 to human intestinal cell lines
    Simone Guglielmetti
    Department of Food Science and Microbiology, University of Milan, Milan, Italy
    Curr Microbiol 59:167-72. 2009
  10. pmc Oral bacteria as potential probiotics for the pharyngeal mucosa
    Simone Guglielmetti
    Dipartimento di Scienze e Tecnologie Alimentari, Universita degli Studi di Milano, Via Celoria 2, 20133 Milan, Italy
    Appl Environ Microbiol 76:3948-58. 2010

Collaborators

Detail Information

Publications29

  1. ncbi request reprint Molecular characterization of Bifidobacterium longum biovar longum NAL8 plasmids and construction of a novel replicon screening system
    Simone Guglielmetti
    Department of Food Science and Microbiology, Industrial Microbiology Section, University of Milan, Via Celoria 2, 20133 Milan, Italy
    Appl Microbiol Biotechnol 74:1053-61. 2007
    ..As a result, we developed a system suitable for avoiding possible interference by other functional replication modules on the vector and for screening functional replicons from wild-type plasmids...
  2. ncbi request reprint TgaA, a VirB1-Like Component Belonging to a Putative Type IV Secretion System of Bifidobacterium bifidum MIMBb75
    Simone Guglielmetti
    Department of Food Environmental and Nutritional Sciences, Universita degli Studi di Milano, Milan, Italy
    Appl Environ Microbiol 80:5161-9. 2014
    ....
  3. ncbi request reprint Murein Lytic Enzyme TgaA of Bifidobacterium bifidum MIMBb75 Modulates Dendritic Cell Maturation through Its Cysteine- and Histidine-Dependent Amidohydrolase/Peptidase (CHAP) Amidase Domain
    Simone Guglielmetti
    Department of Food Environmental and Nutritional Sciences, Universita degli Studi di Milano, Milan, Italy
    Appl Environ Microbiol 80:5170-7. 2014
    ..In conclusion, our study suggests that the bacterial CHAP domain is a novel microbe-associated molecular pattern actively participating in the cross talk mechanisms between bifidobacteria and the host's immune system. ..
  4. pmc Health-Promoting Properties of Lactobacillus helveticus
    Valentina Taverniti
    Division of Food Microbiology and Bioprocesses, Department of Food Environmental and Nutritional Sciences, Università degli Studi di Milano Milan, Italy
    Front Microbiol 3:392. 2012
    ..In conclusion, this review demonstrates that in light of the scientific literature presented, L. helveticus can be included among the bacterial species that are generally considered to be probiotic...
  5. doi request reprint Differential modulation of human intestinal bifidobacterium populations after consumption of a wild blueberry (Vaccinium angustifolium) drink
    Simone Guglielmetti
    Department of Food, Environmental and Nutritional Sciences DeFENS, Division of Food Microbiology and Bioprocessing, Universita degli Studi di Milano, Via Celoria 2, 20133 Milano, Italy
    J Agric Food Chem 61:8134-40. 2013
    ..In conclusion, wild blueberry consumption resulted in a specific bifidogenic effect that could positively affect certain populations of bifidobacteria with demonstrated health-promoting properties...
  6. doi request reprint Luteibacter rhizovicinus MIMR1 promotes root development in barley (Hordeum vulgare L.) under laboratory conditions
    Simone Guglielmetti
    Division of Food Microbiology and Bioprocessing, Department of Food, Environmental and Nutritional Sciences DeFENS, Universita degli Studi di Milano, Via Celoria 2, 20133, Milan, Italy
    World J Microbiol Biotechnol 29:2025-32. 2013
    ..The results obtained in this work make L. rhizovicinus MIMR1 a good candidate for possible use in the formulation of bio-fertilizers...
  7. pmc Biotransformation strategy to reduce allergens in propolis
    Claudio Gardana
    Division of Nutrition, Universita degli Studi di Milano, Milan, Italy
    Appl Environ Microbiol 78:4654-8. 2012
    ..This is the first study demonstrating that the allergenic caffeate esters of propolis can be eliminated by means of a bacterial biotransformation procedure...
  8. pmc In vitro functional and immunomodulatory properties of the Lactobacillus helveticus MIMLh5-Streptococcus salivarius ST3 association that are relevant to the development of a pharyngeal probiotic product
    Valentina Taverniti
    Department of Food Science and Microbiology, Universita degli Studi di Milano, Milan, Italy
    Appl Environ Microbiol 78:4209-16. 2012
    ..In conclusion, we propose the combined use of L. helveticus MIMLh5 and S. salivarius ST3 for the preparation of novel products that display probiotic properties for the pharyngeal mucosa...
  9. ncbi request reprint Study of the adhesion of Bifidobacterium bifidum MIMBb75 to human intestinal cell lines
    Simone Guglielmetti
    Department of Food Science and Microbiology, University of Milan, Milan, Italy
    Curr Microbiol 59:167-72. 2009
    ..bifidum to only restricted distal sites of the gut...
  10. pmc Oral bacteria as potential probiotics for the pharyngeal mucosa
    Simone Guglielmetti
    Dipartimento di Scienze e Tecnologie Alimentari, Universita degli Studi di Milano, Via Celoria 2, 20133 Milan, Italy
    Appl Environ Microbiol 76:3948-58. 2010
    ..They could display a good degree of adaptation to the host and possess potential immunomodulatory and anti-inflammatory properties...
  11. pmc A dairy bacterium displays in vitro probiotic properties for the pharyngeal mucosa by antagonizing group A streptococci and modulating the immune response
    Simone Guglielmetti
    Dipartimento di Scienze e Tecnologie Alimentari, Universita degli Studi di Milano, Milano, Italy
    Infect Immun 78:4734-43. 2010
    ..In conclusion, we propose MIMLh5 as a potential probiotic bacterium for the human pharynx, with promising antagonistic and immunomodulatory properties...
  12. doi request reprint Randomised clinical trial: Bifidobacterium bifidum MIMBb75 significantly alleviates irritable bowel syndrome and improves quality of life--a double-blind, placebo-controlled study
    S Guglielmetti
    Department of Food Science and Microbiology, Universita degli Studi di Milano, Via Celoria 2, Milan, Italy
    Aliment Pharmacol Ther 33:1123-32. 2011
    ..As probiotics have been reported to restore the intestinal microbiota and the gut barrier, the therapeutic potential of probiotics within IBS became of strong interest...
  13. pmc Implication of an outer surface lipoprotein in adhesion of Bifidobacterium bifidum to Caco-2 cells
    Simone Guglielmetti
    Department of Food Science and Microbiology, University of Milan, Via Celoria 2, 20133 Milan, Italy
    Appl Environ Microbiol 74:4695-702. 2008
    ..BopA is the first protein described to date to be directly involved in the adhesion of bifidobacteria to Caco-2 cells and to show immunomodulatory activity...
  14. doi request reprint Construction, characterization and exemplificative application of bioluminescent Bifidobacterium longum biovar longum
    Simone Guglielmetti
    Department of Food Science and Microbiology, University of Milan, Italy
    Int J Food Microbiol 124:285-90. 2008
    ..In sum, our results show that bioluminescent B. longum, transformed with the pGBL8b plasmid, is a valuable tool for rapidly studying the physiological state of anaerobic bacterial cells under different environmental conditions...
  15. pmc Bacterial cinnamoyl esterase activity screening for the production of a novel functional food product
    Simone Guglielmetti
    Department of Food Science and Microbiology, Industrial Microbiology Section, University of Milan, Via Celoria 2, 20133 Milan, Italy
    Appl Environ Microbiol 74:1284-8. 2008
    ..The novel food product was demonstrated to display high total antioxidant power and potential probiotic properties...
  16. ncbi request reprint Small rolling circle plasmids in Bacillus subtilis and related species: organization, distribution, and their possible role in host physiology
    S Guglielmetti
    Department of Food Science and Microbiology, Industrial Microbiology Section, University of Milan, Via Celoria 2, Milan, Italy
    Plasmid 57:245-64. 2007
    ..Finally, the parasitic vs. mutualistic nature of small rolling circle plasmids is briefly discussed...
  17. ncbi request reprint Genetic relationship among Bacillus licheniformis rolling-circle-replicating plasmids and complete nucleotide sequence of pBL63.1, an atypical replicon
    S Guglielmetti
    Department of Food Science and Microbiology, Industrial Microbiology Section, University of Milan, Via Celoria 2, 20133 Milan, Italy
    Plasmid 54:93-103. 2005
    ..pBL63.1 represents an exception to the low-level diversity hypothesis among Bacillus RC replicons...
  18. ncbi request reprint Conditions affecting cell surface properties of human intestinal bifidobacteria
    Enrica Canzi
    Department of Food Science and Microbiology, University of Milan, Via Celoria 2, 20133 Milan, Italy
    Antonie Van Leeuwenhoek 88:207-19. 2005
    ..adolescentis strains, were strictly dependent on the pH of the medium. Moreover, protease treatment experiments suggested that proteins had a key role in the autoaggregating ability of B. bifidum and B. adolescentis strains...
  19. ncbi request reprint Urease biogenesis in Streptococcus thermophilus
    Diego Mora
    Dipartimento di Scienze e Tecnologie Alimentari e Microbiologiche, Universita degli Studi di Milano, Via Celoria 2, 20133 Milan, Italy
    Res Microbiol 156:897-903. 2005
    ..thermophilus is regulated differently compared with that of the closely related S. salivarius. These differences are discussed taking into consideration the different habitats colonized by the two bacterial species...
  20. ncbi request reprint 16S-23S rRNA intergenic spacer region sequence variation in Streptococcus thermophilus and related dairy streptococci and development of a multiplex ITS-SSCP analysis for their identification
    Diego Mora
    Dipartimento di Scienze e Tecnologie Alimentari e Microbiologiche, sezione Microbiologia Industriale, Universita degli Studi di Milano, Milano, Italy
    Microbiology 149:807-13. 2003
    ..thermophilus and S. salivarius strains. With the aim of developing a rapid tool for the identification of the dairy streptococci species a multiplex ITS-SSCP analysis of two discrete regions within the ITS locus was carried out...
  21. pmc Unusual organization for lactose and galactose gene clusters in Lactobacillus helveticus
    Maria Grazia Fortina
    Industrial Microbiology Section, Department of Food Science and Microbiology, University of Milan, 20133 Milan, Italy
    Appl Environ Microbiol 69:3238-43. 2003
    ..In the presence of glucose and galactose galE was transcribed from its promoter, suggesting that the corresponding enzyme can be expressed constitutively. Lactose transport was inducible by addition of lactose to the growth medium...
  22. ncbi request reprint Homologies among three Bacillus licheniformis plasmids and molecular characterization of their replication module
    Carlo Parini
    Department of Food Science and Microbiology, Industrial Microbiology Section, University of Milan, Via Celoria 2, Milan 20133, Italy
    Microbiol Res 159:211-7. 2004
    ..This investigation provides more information concerning phylogeny, interrelationships and level of diversity among Bacillus plasmids and a molecular characterization of three plasmids useful for the construction of cloning vectors...
  23. ncbi request reprint Complete sequence and structural organization of pFL5 and pFL7, two cryptic plasmids from Bacillus licheniformis
    C Parini
    Department of Food Science and Microbiology, University of Milan, Via Celoria 2, 20133, Italy
    Plasmid 51:192-202. 2004
    ..These plasmids seem to be related to plasmids identified within the Bacillus subtilis group, confirming the low-level diversity among these replicons...
  24. pmc Aspartate biosynthesis is essential for the growth of Streptococcus thermophilus in milk, and aspartate availability modulates the level of urease activity
    Stefania Arioli
    Department of Food Science and Microbiology, University of Milan, Via Celoria 2, 20133 Milano, Italy
    Appl Environ Microbiol 73:5789-96. 2007
    ....
  25. ncbi request reprint Mobilome and genetic modification of bifidobacteria
    S Guglielmetti
    Dipartimento di Scienze e Tecnologie Alimentari e Microbiologiche, Sezione di Microbiologia Industriale, Universita degli Studi di Milano, Via Celoria 2, 20133 Milan, Italy
    Benef Microbes 4:143-66. 2013
    ....
  26. ncbi request reprint Carbamoylphosphate synthetase activity is essential for the optimal growth of Streptococcus thermophilus in milk
    S Arioli
    Department of Food Science and Microbiology, University of Milan, Milan, Italy
    J Appl Microbiol 107:348-54. 2009
    ..The aim of the study was to study the role of carbon dioxide metabolism in Streptococcus thermophilus through investigation of the phenotype of a carbamoylphosphate synthetase-negative mutant...
  27. ncbi request reprint Generation and comparison of bioluminescent and fluorescent Bacillus licheniformis
    Isabella Tamagnini
    Department of Food Science and Microbiology, University of Milan, Via Celoria 2, Milan, Italy
    Curr Microbiol 57:245-50. 2008
    ..Thus, the light emission was found to be a reliable, sensitive, and real-time indicator of the "well-being" of cells, whereas fluorescence allowed one to visualize both metabolically active and inactive cells...
  28. doi request reprint The relevance of carbon dioxide metabolism in Streptococcus thermophilus
    Stefania Arioli
    Department of Food Science and Microbiology, Milan, Italy
    Microbiology 155:1953-65. 2009
    ..Our results reveal the capnophilic nature of this micro-organism, underlining the essential role of CO(2) in S. thermophilus physiology, and suggesting potential applications in dairy fermentation processes...
  29. ncbi request reprint Complete nucleotide sequence of pGS18, a 62.8-kb plasmid from Geobacillus stearothermophilus strain 18
    Milda Stuknyte
    Department of Plant Physiology and Microbiology, Faculty of Natural Sciences, Vilnius University, Ciurlionio 21 27, 03101 Vilnius, Lithuania
    Extremophiles 12:415-29. 2008
    ....