Research Topics
| Giovanni GuaraldiSummaryAffiliation: University of Modena and Reggio Emilia Country: Italy Publications
| Collaborators
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Detail Information
Publications
High-density hyaluronic acid for the treatment of HIV-related facial lipoatrophyMarco Pignatti
Department of Plastic and Reconstructive Surgery, Policlinico di Modena, University of Modena and Reggio Emilia, Modena, Italy
Aesthetic Plast Surg 36:180-5. 2012..The objective of our study was to verify the safety and efficacy of a new formulation of high-density hyaluronic acid for the injectable treatment of HIV-related facial lipoatrophy...- Erectile dysfunction is not a mirror of endothelial dysfunction in HIV-infected patientsGiovanni Guaraldi
Metabolic Clinic, Infectious Diseases Unit, Department of Medicine and Medicine Specialities, University of Modena and Reggio Emilia, Modena, Italy
J Sex Med 9:1114-21. 2012..The penis has been compared to a barometer of endothelial health, erectile dysfunction (ED) being an early sign of endothelial dysfunction... - Morphological and metabolic components of lipodystrophy in various nevirapine-based highly active antiretroviral therapy (HAART) regimens: a cross-sectional, observational studyGiovanni Guaraldi
Clinica delle Malattie Infettive, Universita degli Studi di Modena e Reggio Emilia, Modena, Italy
Clin Drug Investig 31:759-67. 2011..Improvements in body shape changes associated with lipodystrophy have also been reported when nevirapine replaced a PI in long-term triple therapy... - Human immunodeficiency virus infection is associated with accelerated atherosclerosisGiovanni Guaraldi
Department of Medicine, Metabolic Clinic, Infectious and Tropical Diseases Unit, University of Modena and Reggio Emilia, Modena, Italy
J Antimicrob Chemother 66:1857-60. 2011..In this pilot study, we compared the progression of coronary artery calcium (CAC) between HIV-infected and uninfected patients... - Human immunodeficiency virus is the major determinant of steatosis and hepatitis C virus of insulin resistance in virus-associated fatty liver diseaseGiovanni Guaraldi
Department of Medicine and Medical Specialties, Metabolic Clinic, Infectious and Tropical Disease Unit, University of Modena and Reggio Emilia, Modena, Italy
Arch Med Res 42:690-7. 2011.... - Progression of coronary artery calcium in men affected by human immunodeficiency virus infectionGiovanni Guaraldi
Metabolic Clinic, Infectious and Tropical Diseases Unit, Department of Medicine, University of Modena and Reggio Emilia, Modena, Italy
Int J Cardiovasc Imaging 28:935-41. 2012..Therefore, immunologic perturbations secondary to HIV infection may contribute to atherosclerosis progression... - Parallel increase of subclinical atherosclerosis and epicardial adipose tissue in patients with HIVStefano Zona
Metabolic Clinic, Infectious and Tropical Diseases Unit, Department of Medicine, University of Modena and Reggio Emilia, Modena, Italy
Am Heart J 163:1024-30. 2012..Epicardial adipose tissue (EAT) may contribute to the development of coronary atherosclerosis via paracrine secretion of inflammatory cytokines... - Coronary aging in HIV-infected patientsGiovanni Guaraldi
Metabolic Clinic, Infectious and Tropical Disease Unit, Department of Medicine, University of Modena and Reggio Emilia, Modena, Italy
Clin Infect Dis 49:1756-62. 2009..We investigated whether the vascular age of a cohort of stable HIV-infected patients receiving antiretroviral therapy (ART) was increased and sought out predictors of increased vascular age... 
Body image is a major determinant of sexual dysfunction in stable HIV-infected womenKety Luzi
Universita di Modena e Reggio Emilia, Modena, Italy
Antivir Ther 14:85-92. 2009..Prevalence and factors associated with sexual dysfunction in HIV-positive women are poorly known...- Nonalcoholic fatty liver disease in HIV-infected patients referred to a metabolic clinic: prevalence, characteristics, and predictorsGiovanni Guaraldi
University of Modena and Reggio Emilia School of Medicine, Modena, Italy
Clin Infect Dis 47:250-7. 2008.... - Detectable HIV viral load is associated with metabolic syndromeNicola Squillace
Department of Medicine and Medical Specialties, Infectious Diseases Clinic, University of Modena and Reggio Emilia, Modena, Italy
J Acquir Immune Defic Syndr 52:459-64. 2009..The aim of our study was to assess the association between HIV viral load (HIV-VL) and metabolic syndrome (MS) in a cohort of HIV-infected patients... - Lipodystrophy and anti-retroviral therapy as predictors of sub-clinical atherosclerosis in human immunodeficiency virus infected subjectsGiovanni Guaraldi
Metabolic Clinic, Infectious and Tropical Disease Unit, Department of Medicine, University of Modena and Reggio Emilia, Modena, Italy
Atherosclerosis 208:222-7. 2010..We assessed the contribution of chronic HIV infection, ART use and LD to the presence of sub-clinical atherosclerosis as evaluated by coronary artery calcium (CAC) imaging... - Effect of treatment interruption monitored by CD4 cell count on mitochondrial DNA content in HIV-infected patients: a prospective studyCristina Mussini
Clinic of Infectious and Tropical Diseases, University of Modena and Reggio Emilia, Modena, Italy
AIDS 19:1627-33. 2005..HIV infection per se and HAART can alter mitochondrial functionality, leading to a decrease in mitochondrial DNA content... - Sexual dysfunction in HIV-infected men: role of antiretroviral therapy, hypogonadism and lipodystrophyGiovanni Guaraldi
Universita di Modena e Reggio Emilia, Modena, Italy
Antivir Ther 12:1059-65. 2007..Both psychological and organic factors have been recognized to be associated with sexual dysfunction in HIV-infected individuals... 
Severity of lipodystrophy is associated with decreased health-related quality of lifeGiovanni Guaraldi
Department of Medicine and Medical Specialties, Infectious Diseases Clinic, University of Modena and Reggio Emilia, Modena, Italy
AIDS Patient Care STDS 22:577-85. 2008..HRQOL was strongly correlated with LD severity when a patient-based score was used. For an overall assessment of the impact of LD on HIV-infected people, both patient-based and physician-based measures are required...- Erectile dysfunction is more common in young to middle-aged HIV-infected men than in HIV-uninfected menStefano Zona
Metabolic Clinic, Infectious Diseases Unit, Department of Medicine and Medical Specialities, University of Modena and Reggio Emilia, Modena, Italy
J Sex Med 9:1923-30. 2012..No studies, however, compared the prevalence of ED in HIV-infected and HIV-uninfected individuals using the international index of erectile function (IIEF-15)... - Magnetic resonance for quantitative assessment of liver steatosis: a new potential tool to monitor antiretroviral-drug-related toxicitiesGiovanni Guaraldi
Metabolic Clinic, Infectious Disease Clinic, Department of Medicine and Medical Specialities, University of Modena and Reggio Emilia, Modena, Italy
Antivir Ther 17:965-71. 2012..The aim of this study was to compare sensitivity and specificity of different MR techniques in the quantitative assessment of liver steatosis, using liver biopsy as the reference standard, in patients with and without HIV infection... - Premature age-related comorbidities among HIV-infected persons compared with the general populationGiovanni Guaraldi
Department of Medicine and Medical Specialities, University of Modena and Reggio Emilia, Italy
Clin Infect Dis 53:1120-6. 2011..We assessed the prevalence and risk factors for NICMs in a large cohort of HIV-infected adults and compared these findings with data from matched control subjects... - First report on a series of HIV patients undergoing rapamycin monotherapy after liver transplantationFabrizio Di Benedetto
Liver and Multivisceral Transplant Center, University of Modena and Reggio Emilia, Modena, Italy
Transplantation 89:733-8. 2010..We present the preliminary results of a prospective nonrandomized trial concerning the first HIV patient series receiving RAPA monotherapy after liver transplantation (LT)... - Epicardial adipose tissue is an independent marker of cardiovascular risk in HIV-infected patientsGiovanni Guaraldi
Metabolic Clinic, Infectious and Tropical Diseases Unit, Department of Medicine, University of Modena and Reggio Emilia, Modena, Italy
AIDS 25:1199-205. 2011.... - Lipodystrophy and quality of life of HIV-infected personsGiovanni Guaraldi
University of Modena and Reggio Emilia, Modena, Italy
AIDS Rev 10:152-61. 2008.... - Metabolic disorders induced by highly active antiretroviral therapy and their relationship with vascular remodeling of the brachial artery in a population of HIV-infected patientsRosario Rossi
Institute of Cardiology, University of Modena and Reggio Emilia Policlinico Hospital, Modena, Italy
Metabolism 58:927-33. 2009.... - Premature decline of serum total testosterone in HIV-infected men in the HAART-eraVincenzo Rochira
Chair and Unit of Endocrinology and Metabolism, Department of Medicine, Endocrinology and Metabolism, Geriatrics, University of Modena and Reggio Emilia, Azienda AUSL NOCSAE of Baggiovara, Modena, Italy
PLoS ONE 6:e28512. 2011..We investigated the gonadal status in HIV-infected men in order to characterize T deficiency and to identify predictive factors for low serum T... - Fusarium verticillioides fungemia in a liver transplantation patient: successful treatment with voriconazoleStefania Cocchi
Clinic of Infectious Diseases, Department of Medicine and Medical Specialities, Microbiology and Virology Laboratories, University of Modena and Reggio Emilia, Azienda Ospedaliero Universitaria Policlinico, Modena, Italy
Diagn Microbiol Infect Dis 71:438-41. 2011..We present a rare case of F. verticillioides fungemia that occurred in a patient who underwent a second orthotopic liver transplantation for chronic rejection and completely responded to treatment with voriconazole... - Ectopic fat is linked to prior cardiovascular events in men with HIVGabriella Orlando
Department of Medicine and Medical Specialties, University of Modena and Reggio Emilia, Modena, Italy
J Acquir Immune Defic Syndr 59:494-7. 2012..13, 95% CI: 1.04 to 1.24, per 10 cm), LF (IRR = 1.17, 95% CI: 1.04 to 1.32), and VAT (IRR = 1.05, 95% CI: 1.00 to 1.10, per 10 cm). Ectopic fat but not general adiposity measures were associated with prevalent CVD in men with HIV... - GH response to GHRH plus arginine is impaired in lipoatrophic women with human immunodeficiency virus compared with controlsLucia Zirilli
Integrated Department of Medicine, University of Modena and Reggio Emilia, Via Giardini 1355, 41100 Modena, Italy
Eur J Endocrinol 166:415-24. 2012..Less is known about the underlying mechanisms involved in reduced GH secretion in HIV-infected women... - Multidisciplinary approach to the treatment of metabolic and morphologic alterations of HIV-related lipodystrophyGiovanni Guaraldi
Department of Medicine and Medical Specialties, Infectious Diseases Clinic, University of Modena and Reggio Emilia, Via del Pozzo 71, 41100 Modena, Italy
HIV Clin Trials 7:97-106. 2006..Treatment for metabolic and morphologic alterations in HIV-related lipodystrophy include medical therapy, physical exercise, and surgical interventions... - Prevalence of and risk factors for pubic lipoma development in HIV-infected personsGiovanni Guaraldi
Department of Medicine and Medical Specialties, Infectious Diseases Clinic, University of Modena and Reggio Emilia, Modena, Italy
J Acquir Immune Defic Syndr 45:72-6. 2007..The natural history of HIV-associated body habitus changes is unclear. In this report, we describe a novel manifestation of HIV-associated lipoaccumulation... - Mitochondrial DNA haplogroups and highly active antiretroviral therapy-related lipodystrophyMilena Nasi
Department of Biomedical Sciences, University of Modena and Reggio Emilia, Italy
Clin Infect Dis 47:962-8. 2008.... - Glomerular filtration rates in HIV-infected patients treated with and without tenofovir: a prospective, observational studyGiovanni Guaraldi
Dipartimento di Medicine e Specialità Mediche, University of Modena and Reggio Emilia, Modena, Italy
J Antimicrob Chemother 63:374-9. 2009.... - Long-term efficacy and safety of polyacrylamide hydrogel injection in the treatment of human immunodeficiency virus-related facial lipoatrophy: a 5-year follow-upGiorgio De Santis
Department of Plastic and Reconstructive Surgery, HIV Metabolic Clinic, Modena, Italy
Plast Reconstr Surg 129:101-9. 2012..Concern regarding potential long-term complications of nonbiodegradable fillers remains. The authors investigated the long-term efficacy and safety of polyacrylamide gel injections... - Comparison of three different interventions for the correction of HIV-associated facial lipoatrophy: a prospective studyGiovanni Guaraldi
HIV Metabolic Clinic, Department of Infectious and Tropical Diseases, University of Modena and Reggio Emilia, Italy
Antivir Ther 10:753-9. 2005..To compare autologous fat transfer (AFT), injections of reabsorbable [polylactic acid (PLA)] and non-reabsorbable [polyacrylamide hydrogel (PAAG)] filler materials for the treatment of HIV-related facial lipoatrophy... - HHV-6A in syncytial giant-cell hepatitisLeonardo Potenza
Department of Oncology and Hematology, University of Modena and Reggio Emilia, Azienda Ospedaliera Policlinico, Modena, Italy
N Engl J Med 359:593-602. 2008..Neither HHV-6B DNA nor late protein was identified in the same follow-up samples from the patient. Thus, HHV-6A may be a cause of syncytial giant-cell hepatitis... - Polyacrylamide hydrogel injection in the management of human immunodeficiency virus-related facial lipoatrophy: a 2-year clinical experienceGiorgio De Santis
Department of Plastic and Reconstructive Surgery, University of Modena and Reggio Emilia, Policlinico di Modena, Via del Pozzo, 71, Modena 41100, Italy
Plast Reconstr Surg 121:644-53. 2008..These results are attributable to its use in limited volume injected at multiple sites and in multiple sittings... - A pilot study on the efficacy, pharmacokinetics and safety of atazanavir in patients with end-stage liver diseaseGiovanni Guaraldi
Department of Internal Medicine and Medical Specialties, Clinic of Infectious Diseases, University of Modena and Reggio Emilia, Modena, Italy
J Antimicrob Chemother 62:1356-64. 2008..Limited biochemical toxicities (including unconjugated hyperbilirubinaemia) and allowance of concomitant administration of tenofovir and PPIs were observed... - Altered mitochondrial RNA production in adipocytes from HIV-infected individuals with lipodystrophyLorenzo Galluzzi
Chair of Immunology, Department of Biomedical Sciences, University of Modena and Reggio Emilia, Modena, Italy
Antivir Ther 10:M91-9. 2005..CONCLUSIONS: Lipodystrophy following treatment with NRTI-containing HAART is associated with a decrease in adipose tissue mtRNAs... - Outcome, incidence, and timing of infectious complications in small bowel and multivisceral organ transplantation patientsGiovanni Guaraldi
Department of Medicine and Medical Specialities, Infectious Diseases Clinic, University of Modena and Reggio Emilia, Modena, Italy
Transplantation 80:1742-8. 2005..In particular, small bowel or multivisceral transplantation is complicated to a greater extent than other grafts as a consequence of infectious complications including sepsis... - T cell activation but not polyfunctionality after primary HIV infection predicts control of viral load and length of the time without therapyAndrea Cossarizza
Department of Surgery, Medicine, Dentistry and Morphological Sciences, University of Modena and Reggio Emilia, Modena, Italy
PLoS ONE 7:e50728. 2012..Our objective was to characterize the polyfunctionality of immune response triggered by PHI, and to characterize immune activation and regulatory T cells, correlating such features to disease progression... - CD4 cell-monitored treatment interruption in patients with a CD4 cell count > 500 x 106 cells/lCristina Mussini
Clinic of Infectious and Tropical Diseases, Azienda Ospedaliero Universitaria Policlinico, University of Modena and Reggio Emilia, Via del Pozzo, 71, 41100 Modena, Italy
AIDS 19:287-94. 2005..Little is known about CD4 cell count changes in patients with high CD4 cell counts who interrupt antiretroviral therapy, especially in those with a nadir of 250-350 x 10 cells/l... - Invasive pulmonary and cerebral aspergillosis in a patient with Weil's diseaseStefania Cocchi
Department of Internal Medicine and Medical Specialities, Infectious Diseases Clinic, Modena, Italy
Scand J Infect Dis 37:396-8. 2005..We describe the successful medical treatment of invasive aspergillosis in a patient suffering from Weil's disease with a combined therapy based on amphotericin B lipid complex and voriconazole... - Facial lipohypertrophy in HIV-infected subjects who underwent autologous fat tissue transplantationGiovanni Guaraldi
Clinica delle Malattie Infettive, Universita degli Studi di Modena e Reggio Emilia, Modena, Italy
Clin Infect Dis 40:e13-5. 2005....