G L Grazi

Summary

Affiliation: University of Bologna
Country: Italy

Publications

  1. ncbi request reprint Using elderly donors in liver transplantation
    G L Grazi
    Liver and Multi Organ Transplant Unit, Sant Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
    Transplant Proc 37:2582-3. 2005
  2. ncbi request reprint A revised consideration on the use of very aged donors for liver transplantation
    G L Grazi
    Department of Surgery and Transplantation, University of Bologna, Italy
    Am J Transplant 1:61-8. 2001
  3. ncbi request reprint Liver resections: complications and survival outcome
    Gian Luca Grazi
    Associate Professor of General Surgery, University of Bologna, Liver and Multi Organ Transplant Unit, Sant Orsola Malpighi Hospital, Bologna, Italy www liversurgery info
    Expert Rev Pharmacoecon Outcomes Res 7:269-79. 2007
  4. ncbi request reprint Web relationships between physicians and individuals seeking information on hepatopancreatobiliary diseases
    Gian Luca Grazi
    Liver and Multi Organ Transplant Unit, University of Bologna, Policlinico Sant Orsola Malpighi, Via Massarenti 9, 40138 Bologna, Italy
    Arch Surg 141:1176-82; discussion 1182. 2006
  5. ncbi request reprint Antimicrobial prophylaxis with ceftriaxone for prevention of early postoperative infections after 49 liver transplantations
    G L Grazi
    Department of Surgery and Liver Transplantation S Orsola Malpighi Hospital, University of Bologna, Italy
    J Chemother 12:10-6. 2000
  6. pmc Improved results of liver resection for hepatocellular carcinoma on cirrhosis give the procedure added value
    G L Grazi
    Department of Surgery and Transplantation, University of Bologna, Policlinico S Orsola Malpighi, Bologna, Italy
    Ann Surg 234:71-8. 2001
  7. doi request reprint Daclizumab and alemtuzumab as induction agents in adult intestinal and multivisceral transplantation: rejection and infection rates in 40 recipients during the early postoperative period
    C Zanfi
    Sant Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
    Transplant Proc 42:35-8. 2010
  8. ncbi request reprint Results of intestinal and multivisceral transplantation in adult patients: Italian experience
    A Lauro
    UO Chirurgia dei Trapianti di Fegato e Multiorgano, University of Bologna, Policlinico S Orsola Malpighi, PAD 25, Via Massarenti 9, 40138 Bologna, Italy
    Transplant Proc 38:1696-8. 2006
  9. doi request reprint Model for End-Stage Liver Disease (MELD) system to allocate and to share livers: experience of two Italian centers
    M Ravaioli
    Department of Liver and Multi organ Transplantation, Sant Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
    Transplant Proc 40:1814-5. 2008
  10. doi request reprint Liver transplantation for recurrent hepatocellular carcinoma on cirrhosis after liver resection: University of Bologna experience
    M Del Gaudio
    Liver and Multiorgan Transplantation Unit, S Orsola Malpighi Hospital, University of Bologna Italy, Bologna, Italy
    Am J Transplant 8:1177-85. 2008

Collaborators

Detail Information

Publications106 found, 100 shown here

  1. ncbi request reprint Using elderly donors in liver transplantation
    G L Grazi
    Liver and Multi Organ Transplant Unit, Sant Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
    Transplant Proc 37:2582-3. 2005
    ..Elderly donors are half of the grafts available in our center for liver transplantation. We retrospectively investigated their characteristics, outcomes, and variables related to graft failure...
  2. ncbi request reprint A revised consideration on the use of very aged donors for liver transplantation
    G L Grazi
    Department of Surgery and Transplantation, University of Bologna, Italy
    Am J Transplant 1:61-8. 2001
    ..Great attention should be paid to the pathological conditions of arterial vessels caused by atherosclerosis, i.e. the presence of calcified plaques on the hepatic artery, which might represent the source of severe complications...
  3. ncbi request reprint Liver resections: complications and survival outcome
    Gian Luca Grazi
    Associate Professor of General Surgery, University of Bologna, Liver and Multi Organ Transplant Unit, Sant Orsola Malpighi Hospital, Bologna, Italy www liversurgery info
    Expert Rev Pharmacoecon Outcomes Res 7:269-79. 2007
    ..For these situations, a consultation should always be performed by a surgeon experienced in hepatic surgery...
  4. ncbi request reprint Web relationships between physicians and individuals seeking information on hepatopancreatobiliary diseases
    Gian Luca Grazi
    Liver and Multi Organ Transplant Unit, University of Bologna, Policlinico Sant Orsola Malpighi, Via Massarenti 9, 40138 Bologna, Italy
    Arch Surg 141:1176-82; discussion 1182. 2006
    ..The Internet has led to widespread Web consulting, the proportions of which are not yet known; there is not yet agreement on its management...
  5. ncbi request reprint Antimicrobial prophylaxis with ceftriaxone for prevention of early postoperative infections after 49 liver transplantations
    G L Grazi
    Department of Surgery and Liver Transplantation S Orsola Malpighi Hospital, University of Bologna, Italy
    J Chemother 12:10-6. 2000
    ....
  6. pmc Improved results of liver resection for hepatocellular carcinoma on cirrhosis give the procedure added value
    G L Grazi
    Department of Surgery and Transplantation, University of Bologna, Policlinico S Orsola Malpighi, Bologna, Italy
    Ann Surg 234:71-8. 2001
    ..To review a single-center experience to update the performance indexes of liver resection (LR)...
  7. doi request reprint Daclizumab and alemtuzumab as induction agents in adult intestinal and multivisceral transplantation: rejection and infection rates in 40 recipients during the early postoperative period
    C Zanfi
    Sant Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
    Transplant Proc 42:35-8. 2010
    ..Induction therapy has enabled improvement in graft and patient survival rates...
  8. ncbi request reprint Results of intestinal and multivisceral transplantation in adult patients: Italian experience
    A Lauro
    UO Chirurgia dei Trapianti di Fegato e Multiorgano, University of Bologna, Policlinico S Orsola Malpighi, PAD 25, Via Massarenti 9, 40138 Bologna, Italy
    Transplant Proc 38:1696-8. 2006
    ..We report our experience with intestinal and multivisceral transplantation in Italy...
  9. doi request reprint Model for End-Stage Liver Disease (MELD) system to allocate and to share livers: experience of two Italian centers
    M Ravaioli
    Department of Liver and Multi organ Transplantation, Sant Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
    Transplant Proc 40:1814-5. 2008
    ..The use of the Model for End-stage Liver Disease (MELD) score to prioritize patients on liver waiting lists and to share organs among centers was effective according to US data, but few reports are available in Europe...
  10. doi request reprint Liver transplantation for recurrent hepatocellular carcinoma on cirrhosis after liver resection: University of Bologna experience
    M Del Gaudio
    Liver and Multiorgan Transplantation Unit, S Orsola Malpighi Hospital, University of Bologna Italy, Bologna, Italy
    Am J Transplant 8:1177-85. 2008
    ..73%, p = NS) and disease-free (48% vs. 71%, p = NS) survival rates were obtained for SLT and primary LT for HCC, respectively. LR is a valid treatment for small HCC and in the event of recurrence, SLT is a safe and effective procedure...
  11. doi request reprint Comprehensive surgical intestinal rescue and transplantation program in adult patients: Bologna experience
    C Zanfi
    Sant Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
    Transplant Proc 42:39-41. 2010
    ..Intestinal transplant surgery is thought to rescue patients in whom complications of total parenteral nutrition (TPN) develop...
  12. ncbi request reprint Rejection episodes and 3-year graft survival under sirolimus and tacrolimus treatment after adult intestinal transplantation
    A Lauro
    U O Chirurgia dei Trapianti di Fegato e Multiorgano, University of Bologna, Policlinico S Orsola Malpighi, Massarenti no 9, Bologna 40138, Italy
    Transplant Proc 39:1629-31. 2007
    ..We focused on Sirolimus (Rapamycin) to examine effects on rejection and graft survival following intestinal transplantation...
  13. ncbi request reprint Daclizumab and alemtuzumab as induction agents in adult intestinal and multivisceral transplantation: A comparison of two different regimens on 29 recipients during the early post-operative period
    A Lauro
    Liver and Multiorgan Transplant Unit, S Orsola Malpighi Hospital, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy
    Dig Liver Dis 39:253-6. 2007
    ..Induction therapy has been recently adopted for intestinal transplant...
  14. doi request reprint Liver transplantation for hepatocellular carcinoma: results of down-staging in patients initially outside the Milan selection criteria
    M Ravaioli
    Department of Liver and Multi organ Transplantation, Pathology Division of The F Addarii Institute, Sant Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
    Am J Transplant 8:2547-57. 2008
    ..The actuarial intention-to-treat survival was 27/48 patients (56.3%) in the down-staging and 81/129 cases (62.8%) in the Milan group, p = n.s. The proposed down-staging criteria provide a comparable outcome to the conventional criteria...
  15. ncbi request reprint Italian experience in adult clinical intestinal and multivisceral transplantation: 6 years later
    A Lauro
    Liver and Multiorgan Transplant Unit, University of Bologna, Policlinico S Orsola Malpighi, Bologna, Italy
    Transplant Proc 39:1987-91. 2007
    ..All patients were adults of median age at transplant of 34.7 years and mean weight 59.6 kg. All recipients were on total parenteral nutrition for a mean time of 38.8 months. Mean donor/recipient body weight ratio was 1.1...
  16. doi request reprint Harm and benefits of primary liver resection and salvage transplantation for hepatocellular carcinoma
    A Cucchetti
    Liver and Multiorgan Transplant Unit, University of Bologna, Italy
    Am J Transplant 10:619-27. 2010
    ..An increased proportion of HCC candidates and/or an increased median time-to-transplant could lead to a benefit for waiting-list patients that outweighs this harm...
  17. ncbi request reprint Incidence, clinical significance, and outcome of vascular alterations in intestinal biopsies after isolated small bowel transplantation: a single-center experience
    M Cescon
    Liver and Multiorgan Transplant Unit, Department of Surgery and Transplantation, Padiglione 25, Policlinico Sant Orsola Malpighi, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy
    Transplant Proc 38:1728-30. 2006
    ..Mild and moderate vascular alterations in intestinal biopsies after isolated small bowel transplantation (SBT) have uncertain clinical significance...
  18. ncbi request reprint Recovery from liver dysfunction after adult isolated intestinal transplantation without liver grafting
    A Lauro
    UO Chirurgia dei Trapianti di Fegato e Multiorgano, Bologna, Italy
    Transplant Proc 38:3620-4. 2006
    ..We sought to evaluate liver function recovery after isolated intestinal transplantation in adults with irreversible intestinal failure...
  19. ncbi request reprint Twenty-five consecutive isolated intestinal transplants in adult patients: a five-yr clinical experience
    A Lauro
    Liver and Multiorgan Transplant Unit, University of Bologna Policlinico S Orsola Malpighi, Bologna, Italy
    Clin Transplant 21:177-85. 2007
    ....
  20. ncbi request reprint Steroids in intestinal transplantation
    A Dazzi
    UO Chirurgia dei Trapianti di Fegato e Multiorgano, University of Bologna, Bologna, Italy
    Clin Transplant 21:265-8. 2007
    ..We evaluated the impact of steroids on survival and post-transplant complications in our experience...
  21. ncbi request reprint Comparison between the fifth and sixth editions of the AJCC/UICC TNM staging systems for hepatocellular carcinoma: multicentric study on 393 cirrhotic resected patients
    G Varotti
    Liver and Multiorgan Transplant Unit, S Orsola Hospital, University of Bologna, Bologna, Italy
    Eur J Surg Oncol 31:760-7. 2005
    ..To compare the prognostic efficacy of the 5th and 6th edition of the TNM staging system for HCC...
  22. doi request reprint Sirolimus in liver transplant recipients: a large single-center experience
    M Vivarelli
    Department of Surgery and Transplantation, University of Bologna, S Orsola Hospital, Italy
    Transplant Proc 42:2579-84. 2010
    ..In conclusion, SRL was an effective immunosuppressant even when used in a CNI-sparing regimen. It was beneficial for patients with recently developed renal dysfunction or neurological disorders...
  23. doi request reprint Psychological adaptation and quality of life of adult intestinal transplant recipients: University of Bologna experience
    L Golfieri
    OU Liver and Multiorgan Transplant Surgery, University of Bologna, Bologna, Italy
    Transplant Proc 42:42-4. 2010
    ..Quality of life and psychological well-being can be seen as important outcome measures of transplantation surgery...
  24. doi request reprint Kidney transplantation combined with other organs in Bologna: an update
    R Bertelli
    Department of Surgery, Intensive Care and Transplantation, Sant Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
    Transplant Proc 40:1867-8. 2008
    ..We retrospectively reviewed our experience in combined liver-kidney (L-KT) and heart-kidney (H-KT) transplantations...
  25. ncbi request reprint The role of liver surgery in the treatment of non-colorectal non-neuroendocrine metastases (NCRNNE). Analysis of 134 resected patients
    G Ercolani
    Department of Emergency, Surgery and Transplants, General Surgery and Transplant Unit, Sant Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
    Minerva Chir 64:551-8. 2009
    ..The aim of this study was to evaluate the role of surgery in the treatment of non-colorectal, non-neuroendocrine (NCRNNE) liver metastases...
  26. ncbi request reprint Liver transplantation with the Meld system: a prospective study from a single European center
    M Ravaioli
    Liver and Multi organ Transplantation, Sant Orsola Malpighi Hospital, University of Bologna, Italy
    Am J Transplant 6:1572-7. 2006
    ..4% vs. 14.9%, p = n.s.) as was the 1-year patient survival on the list (83% vs. 84%, p = n.s.). The Meld allocation system improved the outcome of patients with or without HCC on the list...
  27. ncbi request reprint Interferon-alpha plus ribavirin and amantadine in patients with post-transplant hepatitis C: results of a pilot study
    P Andreone
    Department of Internal Medicine, Cardioangiology and Hepatology, University of Bologna, Italy
    Dig Liver Dis 33:693-7. 2001
    ..Recurrence of hepatitis C after liver transplantation is almost constant and may lead to graft loss. The results of treatment with interferon and/or other agents have been controversial...
  28. ncbi request reprint Isolated resection of segment 8 for liver tumors: a new approach for anatomical segmentectomy
    A Mazziotti
    University of Bologna, S Orsola Hospital, Via Massarenti 9, 40138 Bologna, Italy
    Arch Surg 135:1224-9. 2000
    ..The few reports that deal with isolated resection of section 8 generally describe the use of a deep wedge transparenchymal transection...
  29. ncbi request reprint Coping strategies in intestinal transplantation
    L Golfieri
    Liver and Multiorgan Transplant Unit, Policlinico S Orsola Malpighi, University of Bologna, Bologna, Italy
    Transplant Proc 39:1992-4. 2007
    ..The result suggested that assessment of coping strategies should be explored in intestinal transplant to encourage the use of action-oriented methods and discourage those with possible negative effects...
  30. ncbi request reprint Efficacy of MELD score in predicting survival after liver retransplantation
    M Ravaioli
    Department of Liver and Multiorgan Transplantation, Sant Orsola Malpighi Hospital, University of Bologna, 40138 Bologna, Italy
    Transplant Proc 36:2748-9. 2004
    ..We retrospectively investigated the efficacy of the MELD score to predict the outcome of liver retransplantation and serve as selection criteria...
  31. doi request reprint Criteria for diagnosing benign portal vein thrombosis in the assessment of patients with cirrhosis and hepatocellular carcinoma for liver transplantation
    Fabio Piscaglia
    Division of Internal Medicine, Department of Digestive Disease and Internal Medicine, St Orsola Malpighi University Hospital, Bologna, Italy
    Liver Transpl 16:658-67. 2010
    ..In conclusion, for a patient with HCC and portal vein thrombosis, appropriate investigations can establish whether the thrombosis is benign; patients with HCC and benign portal vein thrombosis are candidates for liver transplantation...
  32. ncbi request reprint Liver resection for hepatocellular carcinoma in cirrhotics and noncirrhotics. Evaluation of clinicopathologic features and comparison of risk factors for long-term survival and tumour recurrence in a single centre
    G L Grazi
    Department of Surgery and Transplantation, Sant Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
    Aliment Pharmacol Ther 17:119-29. 2003
    ..Differences in risk factors for survival and recurrence after liver resection for hepatocellular carcinoma (HCC) in patients with or without cirrhosis are not fully clarified...
  33. ncbi request reprint Surgical approach to complicated intestinal failure for benign disease in adult patients: transplantation or surgical rehabilitation?
    A Lauro
    UO Chirurgia dei Trapianti di Fegato e Multiorgano, University of Bologna, Italy
    Transplant Proc 38:1145-7. 2006
    ..At a 2-year mean follow-up, deaths occurred only in the transplant population. Therefore, intestinal surgical rescue, if successful, is optimal in adult patients...
  34. ncbi request reprint Prosthesis jump graft: an unusual arterial reconstruction in liver transplantation
    E Jovine
    Second Department of Surgery, University of Bologna, S Orsola Hospital, Italy
    Transplantation 65:288-90. 1998
    ..Delaware, Flagstaff, AZ) with an excellent outcome 3 years after the transplant. The prosthesis was necessary because of the impossibility of using the donor iliac arterial grafts due to the presence of widespread atherosclerotic damage...
  35. ncbi request reprint Expression of connective tissue growth factor is a prognostic marker for patients with intrahepatic cholangiocarcinoma
    A Gardini
    Department of Surgery and Transplantation, Surgical Unit, Policlinico S Orsola Malpighi, University of Bologna, Bologna, Italy
    Dig Liver Dis 37:269-74. 2005
    ..Connective tissue growth factor is a member of the 'CCN' protein family. Consistent with its profibrotic properties, it is over-expressed in several human epithelial malignancies...
  36. ncbi request reprint Combined heart and liver transplantation in four adults with familial amyloidosis: experience of a single center
    B Nardo
    Department of Surgery, ICU and Transplantation, University of Bologna, Bologna, Italy
    Transplant Proc 36:645-7. 2004
    ..However, the most compromised patients are more likely to display intraoperative risks, postoperative complications, and worsening of extracardiac, extrahepatic symptoms...
  37. ncbi request reprint Review article: liver transplantation for HCC. Treatment options on the waiting list
    L Bolondi
    Division of Internal Medicine, Department of Internal Medicine and Gastroenterology and Division of General and Transplantation Surgery, University of Bologna, S Orsola Malpighi Hospital, Bologna, Italy
    Aliment Pharmacol Ther 17:145-50. 2003
    ..However, the overall efficacy of this approach will be established only in some years...
  38. ncbi request reprint Clinical trial: peg-interferon alfa-2b and ribavirin for the treatment of genotype-1 hepatitis C recurrence after liver transplantation
    F Lodato
    Department of Digestive Diseases and Internal Medicine, Azienda Ospedaliero Universitaria Policlinico Sant Orsola Malpighi, Bologna, Italy
    Aliment Pharmacol Ther 28:450-7. 2008
    ..Treatment of hepatitis C virus (HCV) recurrence after liver transplantation (LT) is difficult with low response rates...
  39. ncbi request reprint Successful treatment of rhinomaxillary form of mucormycosis infection after liver transplantation: a case report
    G Vetrone
    Liver and Multi organ Transplantation, Sant Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
    Transplant Proc 38:1445-7. 2006
    ..This condition can be successfully treated with early diagnosis and a combination of aggressive surgery and antifungal therapy...
  40. ncbi request reprint Autonomic dysfunction and hyperdynamic circulation in cirrhosis with ascites
    F Trevisani
    Department of Internal Medicine, Cardioangiology and Hepatology, University of Bologna, Italy
    Hepatology 30:1387-92. 1999
    ..46; P =.013). Even closer correlations were found with vagal score. AD (mainly VD) may be involved in the pathogenesis of the hyperdynamic circulatory syndrome of patients with advanced cirrhosis...
  41. ncbi request reprint Mirizzi syndrome with cholecysto-choledocal fistula with a high CA19-9 level mimicking biliary malignancies: a case report
    A Principe
    Department of Surgery and Transplantation, University of Bologna, Italy
    Hepatogastroenterology 50:1259-62. 2003
    ..In cases such as ours with extensive fibrosis and inflamed tissue mimicking cholangiocarcinoma or gallbladder carcinoma, a wide hepaticojejunostomy is required to establish adequate biliary drainage...
  42. doi request reprint MiR-221 controls CDKN1C/p57 and CDKN1B/p27 expression in human hepatocellular carcinoma
    F Fornari
    1Dipartimento di Medicina Interna e Gastroenterologia e Centro di Ricerca Biomedica Applicata, Universita di Bologna, Policlinico S Orsola, Bologna, Italy
    Oncogene 27:5651-61. 2008
    ..These findings establish a basis toward the development of therapeutic strategies aimed at blocking miR-221 in HCC...
  43. ncbi request reprint Increased serum level of xanthine oxidoreductase in liver transplanted patients
    M G Battelli
    Department of Experimental Pathology, University of Bologna, Bologna, Italy
    J Biol Regul Homeost Agents 25:77-84. 2011
    ..We report the elevation of serum XOR during the three weeks following LT for the first time, as well as the influence of the graft reperfusion technique on XOR serum levels...
  44. ncbi request reprint Early onset aggressive hereditary amyloidosis: report of an Italian family with TTR Arg47 mutation
    F Salvi
    Department of Neurological Sciences, University of Bologna at Bellaria Hospital, Bologna, Italy
    Neurol Sci 26:140-2. 2005
    ..Patients with Arg47 or other aggressive TTR amyloidoses should be considered high priority patients for orthotopic liver transplantation...
  45. ncbi request reprint Posttransplant lymphoproliferative disorders in liver transplanted patients: a report of four cases
    S Lorenzini
    Department of Internal Medicine, Cardioangiology and Hepatology, University of Bologna, and Department of Gastroenterology and Internal Medicine, Orsola Malpighi Hospital, Bologna, Italy
    Transplant Proc 38:1477-80. 2006
    ..They are often the result of Epstein-Barr virus (EBV)-induced proliferation of B-lymphocytes in the setting of immunosuppression...
  46. ncbi request reprint Diagnostic dilemmas in biliary strictures mimicking cholangiocarcinoma
    A Principe
    Department of Surgery and Transplantation, University of Bologna, Italy
    Hepatogastroenterology 50:1246-9. 2003
    ..Bile duct strictures may be malignant or benign. In the absence of previous biliary surgery a precise preoperative diagnosis is often difficult, in particular when a tumor mass is absent in the preoperative radiologic findings...
  47. ncbi request reprint Use of prosthetic mesh in difficult abdominal wall closure after small bowel transplantation in adults
    F Di Benedetto
    Liver and Multiorgan Transplant Unit, Sant Orsola Malpighi Hospital, University of Bologna, Massarenti no 9, Bologna 40138, Italy
    Transplant Proc 37:2272-4. 2005
    ..The last patient had mesh as a bridge for a subsequent myocutaneous flap from the thigh. All patients are in good health with well-functioning grafts and no need for parenteral nutrition. No enterocutaneous fistulae were detected...
  48. ncbi request reprint Liver transplantation for hepatocellular carcinoma: further considerations on selection criteria
    Matteo Ravaioli
    Department of Surgery and Transplantation, Surgical Unit, Sant Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
    Liver Transpl 10:1195-202. 2004
    ..In conclusion, the efficacy of tumor selection criteria must be analyzed with the use of preoperative data, to avoid bias of the postoperative evaluation. Tumor volume and alfa-fetoprotein level may improve the selection of patients...
  49. doi request reprint Successful liver transplantation from a 95-year-old donor to a patient with MELD score 36 and delayed graft arterialization
    Gian Luca Grazi
    Am J Transplant 8:725-6. 2008
  50. ncbi request reprint Modified outflow reconstruction with a venous patch in domino liver transplantation
    Matteo Cescon
    Liver and Multiorgan Transplant Unit, Department of Surgery and Transplantation, University of Bologna, Bologna, Italy
    Liver Transpl 13:1756-7. 2007
  51. ncbi request reprint Results of lis2t, a multicenter, randomized study comparing cyclosporine microemulsion with C2 monitoring and tacrolimus with C0 monitoring in de novo liver transplantation
    Gary Levy
    University Health Network, The Toronto Hospital, Toronto, Canada
    Transplantation 77:1632-8. 2004
    ..The incidence of adverse events is comparable except for a significantly higher incidence of diabetes mellitus and diarrhea in the tacrolimus group. Both agents are effective primary immunosuppressants in liver transplant recipients...
  52. ncbi request reprint A new priority policy for patients with hepatocellular carcinoma awaiting liver transplantation within the model for end-stage liver disease system
    Fabio Piscaglia
    Department of Internal Medicine and Gastroenterology, Sant Orsola Malpighi Hospital, Bologna, Italy
    Liver Transpl 13:857-66. 2007
    ..This model allows the timely transplantation of patients with HCC without severely affecting the outcome of patients without HCC...
  53. ncbi request reprint Double-blind comparison of hepatitis C histological recurrence Rate in HCV+ Liver transplant recipients given basiliximab + steroids or basiliximab + placebo, in addition to cyclosporine and azathioprine
    Franco Filipponi
    Liver Transplantation Unit, University of Pisa, Hospital of Cisanello, Via Paradisa 2, 56100 Pisa, Italy
    Transplantation 78:1488-95. 2004
    ..Hepatitis C virus (HCV) recurrence in HCV+ liver transplant recipients is almost inevitable and may be promoted by immunosuppression. We compared the amount of liver damage with regard to usage of steroids and basiliximab...
  54. pmc Modification of acid-base balance in cirrhotic patients undergoing liver resection for hepatocellular carcinoma
    Alessandro Cucchetti
    Department of Surgery and Transplantation, Policlinico Sant Orsola Malpighi, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy
    Ann Surg 245:902-8. 2007
    ..To examine modifications of acid-base balance of cirrhotic patients undergoing hepatectomy for hepatocellular carcinoma (HCC)...
  55. ncbi request reprint Laboratory test variability and model for end-stage liver disease score calculation: effect on liver allocation and proposal for adjustment
    Matteo Ravaioli
    Liver and Multiorgan Transplantation, Sant Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
    Transplantation 83:919-24. 2007
    ..The use of the Model for End-Stage Liver Disease (MELD) score to prioritize patients on liver waiting lists must take the bias of different laboratories into account...
  56. ncbi request reprint Long-term survival after two-stage hepatectomy for colorectal metastases: a case report
    Giorgio Ercolani
    Department of Surgery and Transplantation, University of Bologna, S Orsola Malpighi Hospital, Bologna, Italy
    Hepatogastroenterology 51:592-4. 2004
    ..A case of long-term survival after two-stage hepatectomy for colorectal metastases is reported. Considerations on technical aspects, interval between the two liver resections, role of adjuvant chemotherapy and indications are discussed...
  57. ncbi request reprint Semiannual and annual surveillance of cirrhotic patients for hepatocellular carcinoma: effects on cancer stage and patient survival (Italian experience)
    Franco Trevisani
    Dipartimento di Medicina Interna, Cardioangiologia, Epatologia, Semeiotica Medica, Universita di Bologna, Italy
    Am J Gastroenterol 97:734-44. 2002
    ..However, it has not been proved that this procedure can improve patient survival...
  58. doi request reprint Improving the outcome of liver transplantation with very old donors with updated selection and management criteria
    Matteo Cescon
    Liver and Multiorgan Transplant Unit, Department of Surgery and Transplantation, University of Bologna, Bologna, Italy
    Liver Transpl 14:672-9. 2008
    ..04; group 2 versus group 3, P = 0.03). In conclusion, older donor grafts managed with routine graft biopsy and short ischemia time may work effectively, regardless of the severity of the recipient's liver disease...
  59. ncbi request reprint Xanthine oxidoreductase activity in human liver disease
    Fiorenzo Stirpe
    Department of Experimental Pathology, University of Bologna, Italy
    Am J Gastroenterol 97:2079-85. 2002
    ....
  60. pmc Liver resection for hepatocellular carcinoma on cirrhosis: univariate and multivariate analysis of risk factors for intrahepatic recurrence
    Giorgio Ercolani
    Department of Surgery and Transplantation, Surgical Unit, S Orsola Hospital, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy
    Ann Surg 237:536-43. 2003
    ..To evaluate prognostic factors that could affect disease-free survival and recurrence after liver resection for hepatocellular carcinoma (HCC) on cirrhosis...
  61. ncbi request reprint Speech disorder related to tacrolimus-induced pontine myelinolysis after orthotopic liver transplantation
    Matteo Ravaioli
    Transpl Int 16:507-9. 2003
  62. ncbi request reprint Combined heart and liver transplantation for familial amyloidotic neuropathy: considerations from the hepatic point of view
    Gian Luca Grazi
    Department of Surgery and Transplantation, University of Bologna, Bologna, Italy
    Liver Transpl 9:986-92. 2003
    ..However, the most compromised patients are more exposed to intraoperative risks, postoperative complications, and worsening of extracardiac and extrahepatic symptoms. The need for VVB remains to be evaluated...
  63. doi request reprint Liver transplantation for hepatocellular carcinoma under calcineurin inhibitors: reassessment of risk factors for tumor recurrence
    Marco Vivarelli
    Department of Surgery and Transplantation, University of Bologna, S Orsola Hospital, Via Massarenti 9, Bologna, Italy
    Ann Surg 248:857-62. 2008
    ..We assessed the effect of tacrolimus on recurrence of hepatocellular carcinoma (HCC) after liver transplantation (LT) and compared it with that of the other calcineurin inhibitor, cyclosporine...
  64. ncbi request reprint Operative risk by the lidocaine test (MEGX) in resected patients for HCC on cirrhosis
    Matteo Ravaioli
    Department of Surgery and Transplantation, Surgical Unit, Policlinico S Orsola Malpighi, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy
    Hepatogastroenterology 50:1552-5. 2003
    ..The purpose of this study was to evaluate the clinical usefulness of the preoperative lidocaine test (MEGX) in cirrhotic patients who were candidates for curative liver resection for hepatocellular carcinoma...
  65. ncbi request reprint Long-term survival of recipients of liver grafts from donors older than 80 years: is it achievable?
    Matteo Cescon
    Department of Surgery and Transplantation, Sant Orsola Malpighi Hospital, University of Bologna, Italy
    Liver Transpl 9:1174-80. 2003
    ..Long-term patient and graft survival seem to be achievable, but the high rate and rapidity of HCV reinfection remain a major concern for HCV(+) patients...
  66. pmc The role of lymphadenectomy for liver tumors: further considerations on the appropriateness of treatment strategy
    Giorgio Ercolani
    Departments of Surgery and Transplantation, Sant Orsola Hospital, University of Bologna, Bologna, Italy
    Ann Surg 239:202-9. 2004
    ..To evaluate the role of regional lymphadenectomy in patients with liver tumors...
  67. ncbi request reprint Influence of prognostic factors on the outcome of liver transplantation for hepatocellular carcinoma on cirrhosis: a univariate and multivariate analysis
    Massimo Del Gaudio
    Department of Liver Transplantation, University of Bologna S Orsola Hospital, Via Massarenti, 9, 40138 Bologna, Italy
    Hepatogastroenterology 51:510-4. 2004
    ..The purpose of this study is to select the best candidates for liver transplantation considering several prognostic factors that are related to tumor characteristics...
  68. ncbi request reprint Univariate and multivariate analysis of prognostic factors in the surgical treatment of hepatocellular carcinoma in cirrhotic patients
    Giovanni Ramacciato
    Department of General Surgery, Hepato Biliary Pancreatic Unit, University of Rome La Sapienza II Faculty of Medicine, Sant Andrea Hospital, Rome, Italy
    Hepatogastroenterology 53:898-903. 2006
    ..Evaluation of the short- and long-term outcome of liver resections for HCC in cirrhotic patients...
  69. ncbi request reprint Recovery from liver failure after hepatectomy for hepatocellular carcinoma in cirrhosis: meaning of the model for end-stage liver disease
    Alessandro Cucchetti
    Department of Surgery and Transplantation, University of Bologna, Policlinico S Orsola Malpighi, Bologna, Italy
    J Am Coll Surg 203:670-6. 2006
    ..The model for end-stage liver disease (MELD) is considered an index of hepatic functional reserve, and its assessment on postoperative course may properly identify individuals at risk of liver failure...
  70. ncbi request reprint Sirolimus as the main immunosuppressant in the early postoperative period following liver transplantation: a report of six cases and review of the literature
    Marco Vivarelli
    Department of Surgery and Transplantation, University of Bologna, S Orsola Hospital, Bologna, Italy
    Transpl Int 19:1022-5. 2006
    ..In this cohort of patients, the use of sirolimus appeared safe and provided an adequate prophylaxis against rejection, even though the drug was administered in the immediate postoperative period after LT...
  71. ncbi request reprint Split-liver transplantation with pediatric donors: a multicenter experience
    Matteo Cescon
    Centro Trapianti di Fegato, Chirurgia III, Ospedali Riuniti, Bergamo, Italy
    Transplantation 79:1148-53. 2005
    ..Outcomes of split-liver transplantation (SLT) with pediatric donors have never been specifically reported...
  72. ncbi request reprint Liver allocation for hepatocellular carcinoma: a European Center policy in the pre-MELD era
    Matteo Ravaioli
    Department of Liver and Multiorgan Transplantation, Sant Orsola Malpighi Hospital, University of Bologna, Italy
    Transplantation 81:525-30. 2006
    ..Policies to decrease dropout during waiting time for liver transplantation (LT) are under debate...
  73. ncbi request reprint Plasma total homocysteine and cardiovascular risk in patients submitted to liver transplantation
    Giampaolo Bianchi
    Dipartimento di Medicina Interna, Cardioangiologia, Epatologia, Universita di Bologna, Policlinico S Orsola Malpighi, Bologna, Italy
    Liver Transpl 12:105-11. 2006
    ..In conclusion, high Hcy may be involved in the pathogenesis of cardiovascular events in OLT patients. The usefulness of Hcy-lowering therapy remains to be verified...
  74. ncbi request reprint Partial necrosis on hepatocellular carcinoma nodules facilitates tumor recurrence after liver transplantation
    Matteo Ravaioli
    Department of Liver and Multi organ Transplantation, Sant Orsola Malpighi Hospital, University of Bologna, Italy
    Transplantation 78:1780-6. 2004
    ..The presence of partial necrosis in hepatocellular carcinoma (HCC) nodules is a common histologic finding after liver transplantation, but its correlation with tumor recurrence has never been investigated...
  75. ncbi request reprint Mobilization of bone marrow-derived hematopoietic and endothelial stem cells after orthotopic liver transplantation and liver resection
    Roberto M Lemoli
    Institute of Hematology and Medical Oncology L and A Seragnoli, Bologna, Italy
    Stem Cells 24:2817-25. 2006
    ....
  76. ncbi request reprint Tumor doubling time predicts recurrence after surgery and describes the histological pattern of hepatocellular carcinoma on cirrhosis
    Alessandro Cucchetti
    Dipartimento di Discipline Chirurgiche, Rianimatorie e dei Trapianti, University of Bologna, Policlinico S Orsola, Via Massarenti 9, 40138 Bologna, Italy
    J Hepatol 43:310-6. 2005
    ..The prognostic significance of HCC doubling time (DT) after surgery has never been investigated...
  77. ncbi request reprint 12-month follow-up analysis of a multicenter, randomized, prospective trial in de novo liver transplant recipients (LIS2T) comparing cyclosporine microemulsion (C2 monitoring) and tacrolimus
    Gary Levy
    University Health Network, Toronto General Hospital, Toronto, ON, Canada
    Liver Transpl 12:1464-72. 2006
    ..More patients required antidiabetic therapy with tacrolimus regardless of diabetic status at baseline...
  78. ncbi request reprint The future challenge in the MELD era: how to match extended-use donors and sick recipients
    Matteo Ravaioli
    Transplantation 82:987-8. 2006
  79. pmc Feasibility and limits of split liver transplantation from pediatric donors: an italian multicenter experience
    Matteo Cescon
    Liver and Lung Transplantation Unit, Azienda Ospedaliera Ospedali Riuniti, Bergamo, Italy
    Ann Surg 244:805-14. 2006
    ..To report the results of a multicenter experience of split liver transplantation (SLT) with pediatric donors...
  80. ncbi request reprint Causes of early acute graft failure after liver transplantation: analysis of a 17-year single-centre experience
    Giovanni Varotti
    Department of Surgery and Transplantation, Liver and Multiorgan Transplantation Unit, S Orsola Hospital, University of Bologna, Italy
    Clin Transplant 19:492-500. 2005
    ..Nevertheless, a better understanding of the clinical situations and changes in treatment strategies have led to significant improvements in terms of graft and patient survival rates, now close to the survival rate of EAGF-free patients...
  81. ncbi request reprint Relevance of biologic markers in colorectal carcinoma: a comparative study of a broad panel
    Chiara Barozzi
    Pathology Division, Department of Oncohematology, F Addarii Institute, University School of Medicine, Bologna, Italy
    Cancer 94:647-57. 2002
    ....
  82. ncbi request reprint Impact of model for end-stage liver disease (MELD) score on prognosis after hepatectomy for hepatocellular carcinoma on cirrhosis
    Alessandro Cucchetti
    Department of Surgery and Transplantation, University of Bologna, Policlinico Sant Orsola Malpighi, Bologna, Italy
    Liver Transpl 12:966-71. 2006
    ..1%). In conclusion, the MELD score can accurately predict postoperative liver failure and morbidity of cirrhotic patients referred for resection of HCC and should be used to select the best candidates for hepatectomy...
  83. ncbi request reprint Impact of biliary complications in right lobe living donor liver transplantation
    Giovanni Ramacciato
    Department of Surgery and Transplantations, Liver and Multiorgan Transplantation Unit, S Orsola Hospital, University of Bologna, Italy
    Transpl Int 19:122-7. 2006
    ..Nevertheless, attention and surgical refinement can lead to a significant reduction of the biliary complication rate, improving graft and patient survival...
  84. ncbi request reprint Surgical therapy for hepatolithiasis: a Western experience
    Gaetano Vetrone
    Department of Liver and Multiorgan Transplantation, Sant Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
    J Am Coll Surg 202:306-12. 2006
    ..The goal of this study was to analyze the perioperative and longterm results of surgical therapy for hepatolithiasis...
  85. ncbi request reprint Application of a fluorescent PCR method for molecular diagnosis of posttransplant lymphoproliferative disorders on routine tissue sections
    Elisa Gruppioni
    Molecular and Transplantation Pathology Laboratory of the F Addarii Institute of Oncology, S Ozsola Malpighi Hospital, University of Bologna, Bologna, Italy
    Diagn Mol Pathol 14:170-6. 2005
    ..This rapid and straightforward procedure, which allows identification of a wide range of IgH rearrangements, could facilitate molecular analysis of PTLD in routine practice, while limiting consumption of valuable diagnostic material...
  86. ncbi request reprint Embryonal rhabdomyosarcoma of the orbit in a liver transplant recipient
    Matteo Cescon
    Department of Surgery and Transplantation, Policlinico S Orsola, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy
    Transpl Int 16:437-40. 2003
    ..Complete control of tumor growth was achieved, while no alterations of graft function were observed throughout the treatment period...
  87. ncbi request reprint GADD45-alpha expression in cirrhosis and hepatocellular carcinoma: relationship with DNA repair and proliferation
    Laura Gramantieri
    Center for Applied Biomedical Research CRBA, Saint Orsola Malpighi University Hospital, University of Bologna, 40138 Bologna, Italy
    Hum Pathol 36:1154-62. 2005
    ..GADD45-alpha protein levels were higher in HCCs with DNA-bound CDKN1A and PCNA, suggesting a possible role in DNA repair...
  88. ncbi request reprint Outcome of right hepatectomies in patients older than 70 years
    Matteo Cescon
    Department of Surgery and Transplantation, University of Bologna, Bologna, Italy
    Arch Surg 138:547-52. 2003
    ..The increasing number of elderly patients undergoing liver resections mandates updating of clinical outcomes on this specific population...
  89. ncbi request reprint Liver resection for multiple colorectal metastases: influence of parenchymal involvement and total tumor volume, vs number or location, on long-term survival
    Giorgio Ercolani
    Department of Surgery and Transplantation, S Orsola Malpighi Hospital, University of Bologna, Italy
    Arch Surg 137:1187-92. 2002
    ..Multiple and/or bilateral liver metastases are not absolute contraindications to surgical resection...
  90. ncbi request reprint Effect of ischemic preconditioning in whole liver transplantation from deceased donors. A pilot study
    Matteo Cescon
    Liver and Multiorgan Transplant Unit, Department of Surgery and Transplantation, University of Bologna, Bologna, Italy
    Liver Transpl 12:628-35. 2006
    ..007; IPC-, P = 0.003). Prereperfusion and postreperfusion apoptosis was minimal in both groups. In conclusion, IPC reduced ischemia/reperfusion injury through a decrease of hepatocellular necrosis, but it showed no clinical benefits...
  91. ncbi request reprint Histological recurrent hepatitis C after liver transplantation: Outcome and role of retransplantation
    Giorgio Ercolani
    Department of Surgery and Transplantation, Sant Orsola Malpighi, University of Bologna, Bologna, Italy
    Liver Transpl 12:1104-11. 2006
    ..Outcome is quite dismal in patients with early HCV recurrence requiring retransplantation within 1 yr of first OLT...
  92. ncbi request reprint The role of liver resections for noncolorectal, nonneuroendocrine metastases: experience with 142 observed cases
    Giorgio Ercolani
    Department of Surgery and Transplantation, University of Bologna, Hospital Sant Orsola Malpighi, Via Massarenti 9, 40138 Bologna, Italy
    Ann Surg Oncol 12:459-66. 2005
    ..To evaluate the role of liver resection for noncolorectal, nonneuroendocrine metastases, indications and results were retrospectively reviewed in 142 observed patients...
  93. ncbi request reprint Iliac approach for vascularization of an intestinal graft at retransplantation
    Gian Luca Grazi
    Transplantation 82:1112-3. 2006
  94. ncbi request reprint Detection of recipient's cells in liver graft using antibodies to mismatched HLA class I antigens
    Alberto Grassi
    University of Bologna S Orsola Hospital, Bologna, Italy
    Liver Transpl 10:1406-14. 2004
    ..Engraftment by R epithelial cells seems to be less important than previously reported...
  95. ncbi request reprint Hepatic artery stenosis in liver transplanted patients treated with pegylated interferon alpha-2b and ribavirin
    Maurizio Biselli
    Transplantation 78:953. 2004
  96. ncbi request reprint Adjuvant, adoptive immunotherapy with tumor infiltrating lymphocytes plus interleukin-2 after radical hepatic resection for colorectal liver metastases: 5-year analysis
    Andrea Gardini
    Department of Surgery and Transplantation, University of Bologna, Bologna, Italy
    J Surg Oncol 87:46-52. 2004
    ..We assessed the usefulness of immunotherapy with tumor infiltrating lymphocytes (TIL) plus Interleukin-2 (IL-2) as adjuvant treatment...
  97. pmc Predictive indices of morbidity and mortality after liver resection
    G Ercolani
    Ann Surg 244:635-7; author reply 637. 2006
  98. ncbi request reprint Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma
    Laura Gramantieri
    Dipartimento di Medicina Interna e Gastroenterologia e Centro di Ricerca Biomedica Applicata, Universita di Bologna, Bologna, Italy
    Cancer Res 67:6092-9. 2007
    ..These results indicate that cyclin G1 is a target of miR-122a and expand our knowledge of the molecular alterations involved in HCC pathogenesis and of the role of miRNAs in human cancer...
  99. ncbi request reprint Right-side approach to the left caudate lobe in the piggy-back technique of liver transplantation. A further step in maximizing preservation of the retrohepatic inferior vena cava
    Gian Luca Grazi
    Transpl Int 16:361-3. 2003
  100. ncbi request reprint Can antiplatelet prophylaxis reduce the incidence of hepatic artery thrombosis after liver transplantation?
    Marco Vivarelli
    Department of Surgery and Transplantation, University of Bologna, S Orsola Hospital, Bologna, Italy
    Liver Transpl 13:651-4. 2007
    ..There were no hemorrhagic complications associated with the use of aspirin. In conclusion,antiplatelet prophylaxis can effectively reduce the incidence of late HAT after LT, particularly in those patients at risk for this complication...
  101. ncbi request reprint Aberrant Notch3 and Notch4 expression in human hepatocellular carcinoma
    Laura Gramantieri
    Center for Applied Biomedical Research CRBA, University of Bologna and St Orsola Malpighi University Hospital, Bologna, Italy
    Liver Int 27:997-1007. 2007
    ..Notch signalling is altered in several solid tumours and it plays a role in growth inhibition and apoptosis of hepatocellular carcinoma (HCC)-derived cell lines, bile duct development and hepatocyte regeneration...