Giovanni Grasso

Summary

Affiliation: University of Palermo
Country: Italy

Publications

  1. ncbi request reprint The role of erythropoietin in neuroprotection: therapeutic perspectives
    Giovanni Grasso
    Department of Neurosurgery, University of Palermo, Palermo, Italy
    Drug News Perspect 20:315-20. 2007
  2. pmc Unusual recurrence of trigeminal neuralgia after microvascular decompression by muscle interposal
    Giovanni Grasso
    Neurosurgical Clinic, Department of Clinic Neurosciences, University of Palermo, Palermo, Italy
    Med Sci Monit 17:CS43-6. 2011
  3. ncbi request reprint Neuroprotective potential of erythropoietin and darbepoetin alfa in an experimental model of sciatic nerve injury. Laboratory investigation
    Giovanni Grasso
    Neurosurgical Clinic, Department of Clinical Neurosciences, University of Palermo, Italy
    J Neurosurg Spine 7:645-51. 2007
  4. ncbi request reprint Erythropoietin: a new paradigm for neuroprotection
    Giovanni Grasso
    Department of Neurosurgery, University of Palermo School of Medicine, Via del Vespro, 90100 Palermo, Italy
    J Neurosurg Anesthesiol 18:91-2. 2006
  5. ncbi request reprint Neuroprotective effect of erythropoietin and darbepoetin alfa after experimental intracerebral hemorrhage
    Giovanni Grasso
    Neurosurgical Clinic, Department of Clinical Neurosciences, University of Palermo, Palermo, Italy
    Neurosurgery 65:763-9; discussion 769-70. 2009
  6. ncbi request reprint Aneurysm clipping following endovascular coil embolization: a report of two cases
    Giovanni Grasso
    Department of Clinic Neurosciences, Neurosurgical Clinic, University of Palermo, Palermo, Italy
    Med Sci Monit 15:CS63-6. 2009
  7. ncbi request reprint Chronic inflammation causing spinal cord compression in human immunodeficiency virus infection
    Giovanni Grasso
    Neurosurgical Clinic, Department of Clinical Neuroscience, University of Palermo, Italy
    Med Sci Monit 14:CS134-7. 2008
  8. ncbi request reprint Neuroprotection by erythropoietin administration after experimental traumatic brain injury
    Giovanni Grasso
    Department of Clinical Neurosciences, Neurosurgical Clinic, University of Palermo, Italy
    Brain Res 1182:99-105. 2007
  9. ncbi request reprint Erythropoietin and erythropoietin receptor expression after experimental spinal cord injury encourages therapy by exogenous erythropoietin
    Giovanni Grasso
    Department of Neurosurgery, University of Messina, Messina, Italy
    Neurosurgery 56:821-7; discussion 821-7. 2005
  10. pmc Beneficial effects of systemic administration of recombinant human erythropoietin in rabbits subjected to subarachnoid hemorrhage
    Giovanni Grasso
    Department of Neurosurgery, University of Messina, 98122 Messina, Italy
    Proc Natl Acad Sci U S A 99:5627-31. 2002

Collaborators

  • Francesco Tomasello
  • M Buemi
  • Vincenzo Fodale
  • Alfredo Conti
  • Gioacchino Calapai
  • Gerardo Caruso
  • Fabio Carletti
  • Thomas Coleman
  • M Brines
  • P Ghezzi
  • L Torup
  • G Cavaletti
  • A Quartarone
  • R Latini
  • Fortunato Battaglia
  • Roberto Bianchi
  • Cetty Alafaci
  • Alessio Sturiale
  • Alessandra Sfacteria
  • Marcel Leist
  • Maria A Catania
  • Serhat Erbayraktar
  • Marco Bonifazi
  • Maria Bellomo
  • Necati Gokmen
  • Zubeyde Erbayraktar
  • Carla Cerami-Hand
  • Lone Helboe
  • Anthony Cerami
  • Pia Villa
  • Qiao wen Xie
  • Maddalena Fratelli
  • Thomas Sager
  • Osman Yilmaz
  • Søren Christensen
  • Marcello Passalacqua
  • Mariella Caffo
  • Francesco Maria Salpietro
  • Eleonora Crasci
  • Tina Colombo
  • Alessandra Gilardini
  • Maurizio D'Incalci
  • Davide Bolignano
  • Giuseppe Piedemonte
  • Giuseppe Coppolino
  • Patrizia Beccaglia
  • Norberto Oggioni
  • Giuseppe Lauria
  • Virginia Rodriguez-Menendez
  • Susanna Campo
  • Annalisa Canta
  • Giulia De Michele
  • Sara Martone
  • Marzia Mencarelli
  • A P Caputi
  • Leda Lodi
  • Herbert Marini
  • Michela Muscettola
  • Rosario Giuffrida
  • Andrea Felici
  • Giancarlo Carli
  • Anna Lisa Suman
  • Mauro Giacca
  • Elena B Adamo
  • R Marini
  • Fraqncesco Squadrito
  • Carmen Mannucci
  • Caterina Cambiaggi
  • Costanza Savino
  • Marina Bianchi
  • Mette Nielsen
  • Jacob Nielsen
  • Anna Kirstine Larsen
  • Lars O Pedersen
  • Jens Gerwien
  • Pekka Kallunki
  • Lars Østergaard Pedersen
  • Jean Paul Wuerth
  • Domenicantonio Collufio
  • Simona Casagrande
  • Francesco M Salpietro
  • Concetta Alafaci
  • Antonio Morabito
  • Jens Gerwein
  • Mads Kreilgaard
  • Marie Aavang Geist
  • Achille P Caputi
  • Maria C Marciano
  • Alessandra Parisi
  • Francesco Squadrito

Detail Information

Publications35

  1. ncbi request reprint The role of erythropoietin in neuroprotection: therapeutic perspectives
    Giovanni Grasso
    Department of Neurosurgery, University of Palermo, Palermo, Italy
    Drug News Perspect 20:315-20. 2007
    ..The successful trial using EPO in patients with ischemic stroke and the large body of experimental evidence encourages intensive evaluation of this cytokine to support safe and larger clinical trials in the near future...
  2. pmc Unusual recurrence of trigeminal neuralgia after microvascular decompression by muscle interposal
    Giovanni Grasso
    Neurosurgical Clinic, Department of Clinic Neurosciences, University of Palermo, Palermo, Italy
    Med Sci Monit 17:CS43-6. 2011
    ..However, re-operation should be considered in selected patients...
  3. ncbi request reprint Neuroprotective potential of erythropoietin and darbepoetin alfa in an experimental model of sciatic nerve injury. Laboratory investigation
    Giovanni Grasso
    Neurosurgical Clinic, Department of Clinical Neurosciences, University of Palermo, Italy
    J Neurosurg Spine 7:645-51. 2007
    ....
  4. ncbi request reprint Erythropoietin: a new paradigm for neuroprotection
    Giovanni Grasso
    Department of Neurosurgery, University of Palermo School of Medicine, Via del Vespro, 90100 Palermo, Italy
    J Neurosurg Anesthesiol 18:91-2. 2006
  5. ncbi request reprint Neuroprotective effect of erythropoietin and darbepoetin alfa after experimental intracerebral hemorrhage
    Giovanni Grasso
    Neurosurgical Clinic, Department of Clinical Neurosciences, University of Palermo, Palermo, Italy
    Neurosurgery 65:763-9; discussion 769-70. 2009
    ..The objectives of this study were to analyze whether the systemic administration of recombinant human EPO (rHuEPO) and its long-lasting derivative darbepoetin alfa expedited functional recovery and brain damage in a rat model of ICH...
  6. ncbi request reprint Aneurysm clipping following endovascular coil embolization: a report of two cases
    Giovanni Grasso
    Department of Clinic Neurosciences, Neurosurgical Clinic, University of Palermo, Palermo, Italy
    Med Sci Monit 15:CS63-6. 2009
    ..This procedure is attractive as a minimally invasive approach to treat cerebral aneurysms; however, is not devoid of complications or failure and retreatment, with either a surgical or endovascular technique, may often be required...
  7. ncbi request reprint Chronic inflammation causing spinal cord compression in human immunodeficiency virus infection
    Giovanni Grasso
    Neurosurgical Clinic, Department of Clinical Neuroscience, University of Palermo, Italy
    Med Sci Monit 14:CS134-7. 2008
    ..Although rarely reported, spinal cord compression, in the setting of AIDS, has been associated with primary lymphoma or opportunistic infections...
  8. ncbi request reprint Neuroprotection by erythropoietin administration after experimental traumatic brain injury
    Giovanni Grasso
    Department of Clinical Neurosciences, Neurosurgical Clinic, University of Palermo, Italy
    Brain Res 1182:99-105. 2007
    ..4+/-5.4 mm3 versus 37.1+/-5.3 mm3, P<0.05). EPO, administered in its recombinant form, affords significant neuroprotection in experimental TBI model and may hold promise for future clinical applications...
  9. ncbi request reprint Erythropoietin and erythropoietin receptor expression after experimental spinal cord injury encourages therapy by exogenous erythropoietin
    Giovanni Grasso
    Department of Neurosurgery, University of Messina, Messina, Italy
    Neurosurgery 56:821-7; discussion 821-7. 2005
    ....
  10. pmc Beneficial effects of systemic administration of recombinant human erythropoietin in rabbits subjected to subarachnoid hemorrhage
    Giovanni Grasso
    Department of Neurosurgery, University of Messina, 98122 Messina, Italy
    Proc Natl Acad Sci U S A 99:5627-31. 2002
    ..05), ischemic neuronal damage (P < 0.001), and subsequent neurological deterioration (P < 0.05). These observations suggest that r-Hu-EPO may provide an effective treatment to reduce the post-SAH morbidity...
  11. ncbi request reprint Amelioration of spinal cord compressive injury by pharmacological preconditioning with erythropoietin and a nonerythropoietic erythropoietin derivative
    Giovanni Grasso
    Department of Neurosurgery, University of Palermo, Italy
    J Neurosurg Spine 4:310-8. 2006
    ....
  12. ncbi request reprint Does administration of recombinant human erythropoietin attenuate the increase of S-100 protein observed in cerebrospinal fluid after experimental subarachnoid hemorrhage?
    Giovanni Grasso
    Department of Neurosurgery, University of Messina, Policlinico Universitario, Italy
    J Neurosurg 96:565-70. 2002
    ....
  13. ncbi request reprint Assessment of human brain water content by cerebral bioelectrical impedance analysis: a new technique and its application to cerebral pathological conditions
    Giovanni Grasso
    Department of Neurosurgery, University of Messina, Messina, Italy
    Neurosurgery 50:1064-72; discussion 1072-4. 2002
    ..We present a quantitative, in vivo, bioelectrical impedance analysis (BIA) method and propose its use for the accurate assessment of brain water content among human subjects...
  14. ncbi request reprint Cerebellar hematoma in a patient with Marfan syndrome
    Marcello Passalacqua
    Department of Neurosurgery, University of Messina, Italy
    Med Sci Monit 9:CS77-9. 2003
    ..Few case reports have associated Marfan syndrome with vascular malformations of the brain and spinal cord. In this regard, association with intracranial aneurysm has been vaguely proposed...
  15. ncbi request reprint Landmarks for vertebral artery repositioning in bulbar compression syndrome: anatomic and microsurgical nuances
    Giovanni Grasso
    Department of Neurosurgery, University of Messina, Messina, Italy
    Neurosurgery 56:160-4; discussion 160-4. 2005
    ....
  16. ncbi request reprint An overview of new pharmacological treatments for cerebrovascular dysfunction after experimental subarachnoid hemorrhage
    Giovanni Grasso
    Department of Neurosurgery, University of Messina, Via C Valeria 1, 98122, Messina, Italy
    Brain Res Brain Res Rev 44:49-63. 2004
    ..In addition, it points out rHuEPO, which may hold promise in future clinical trials to prevent the occurrence of vasospasm and cerebral ischemia after SAH...
  17. doi request reprint Typical trigeminal neuralgia by an atypical compression: case report and review of the literature
    Giovanni Grasso
    University of Palermo, Department of Experimental Biomedicine and Clinical Neurosciences, Neurosurgical Clinic, Palermo, Italy
    Turk Neurosurg 24:82-5. 2014
    ..Although neurovascular compression is often associated with trigeminal neuralgia, other intracranial pathologies can result in compression along the nerve...
  18. ncbi request reprint Cyberknife radiosurgery for cranial plasma cell tumor
    Cetty Alafaci
    University of Messina, Department of Neurosurgery, Messina, Italy
    Turk Neurosurg 24:272-5. 2014
    ..A technical description of this case is provided. To our knowledge, this is the first case of successful Cyberknife radiosurgery of multifocal intracranial plasmacytoma. ..
  19. ncbi request reprint Hemostasis in brain tumor surgery using the Aquamantys system
    Giovanni Grasso
    Section of Neurosurgery, Department of Experimental Biomedicine and Clinical Neurosciences BioNeC, University of Palermo, Palermo, Italy
    Med Sci Monit 20:538-43. 2014
    ....
  20. ncbi request reprint Erythropoiesis and neuroprotection: two sides of the same coin?
    Giovanni Grasso
    Department of Neurosurgery, University of Messina, Messina, Italy
    Lancet Neurol 2:332. 2003
  21. ncbi request reprint Brain and cancer: the protective role of erythropoietin
    Michele Buemi
    Chair of Nephrology, Department of Internal Medicine, University of Messina, Italy
    Med Res Rev 25:245-59. 2005
    ....
  22. ncbi request reprint Derivatives of erythropoietin that are tissue protective but not erythropoietic
    Marcel Leist
    H Lundbeck A S, 2500 Valby, Denmark
    Science 305:239-42. 2004
    ....
  23. ncbi request reprint Erythropoietin as a tissue-protective cytokine in brain injury: what do we know and where do we go?
    Giovanni Grasso
    University of Messina, Messina, Italy
    Neuroscientist 10:93-8. 2004
    ..Here, the authors characterize the biology of the local tissue-protective system, review data that support this concept, and suggest why non-hematopoietic analogues of EPO may be better choices as therapeutics...
  24. ncbi request reprint Changes in salivary cortisol and corticosteroid receptor-alpha mRNA expression following a 3-week multidisciplinary treatment program in patients with fibromyalgia
    Marco Bonifazi
    Dipartimento di Fisiologia, Via Aldo Moro, Universita degli Studi di Siena, I 53100 Siena, Italy
    Psychoneuroendocrinology 31:1076-86. 2006
    ....
  25. pmc Erythropoietin mediates tissue protection through an erythropoietin and common beta-subunit heteroreceptor
    Michael Brines
    Kenneth S Warren Institute, Ossining, NY 10563, USA
    Proc Natl Acad Sci U S A 101:14907-12. 2004
    ..These data support the concept that EpoR and betacR comprise a tissue-protective heteroreceptor...
  26. ncbi request reprint Erythropoietin prevents cognition impairment induced by transient brain ischemia in gerbils
    Maria A Catania
    Department of Clinical and Experimental Medicine and Pharmacology, Section of Pharmacology, School of Medicine, University of Messina, Via Consolare Valeria, Policlinico Universitario Torre Biologica No 5 piano 98124 Messina, Italy
    Eur J Pharmacol 437:147-50. 2002
    ..These data indicate that recombinant human erythropoietin neuroprotective effects in brain ischemia are associated with the preservation of learning function...
  27. ncbi request reprint Brain dysfunction in uremia: a question of cortical hyperexcitability?
    Fortunato Battaglia
    Department of Physiology and Pharmacology, City University of New York Medical School, New York, NY, USA
    Clin Neurophysiol 116:1507-14. 2005
    ..To investigate whether patients with end-stage renal disease (ESRD) in different stages of the disease and undergoing different treatments display alterations in cortical excitability...
  28. ncbi request reprint Recombinant human erythropoietin (rHuEPO): more than just the correction of uremic anemia
    Michele Buemi
    Department of Internal Medicine, University of Messina, Italy
    J Nephrol 15:97-103. 2002
    ....
  29. pmc Asialoerythropoietin is a nonerythropoietic cytokine with broad neuroprotective activity in vivo
    Serhat Erbayraktar
    The Kenneth S Warren Institute, Kitchawan, NY 10562, USA
    Proc Natl Acad Sci U S A 100:6741-6. 2003
    ..These data suggest that nonerythropoietic variants of rhEPO can cross the blood-brain barrier and provide neuroprotection...
  30. ncbi request reprint Neuroprotective properties of xenon and helium in an in vitro model of traumatic brain injury: one small step or one big jump?
    Vincenzo Fodale
    Crit Care Med 36:647-8. 2008
  31. ncbi request reprint Vascular endothelial growth factor induces brain erythropoietin expression?
    Maria Bellomo
    Department of Biochemical, Physiological and Nutritional Sciences, Section of Physiology and Human Nutrition, AOU Policinico G Martino, University of Messina, Italy
    Funct Neurol 21:87-91. 2006
    ..This finding could help to clarify the functional role of EPO and the molecular mechanisms by which VEGF might mediate its effects in the brain...
  32. ncbi request reprint A new computed-assisted technique for experimental sciatic nerve function analysis
    Giovanni Grasso
    Department of Veterinary Pathology, University of Messina, Messina, Italy
    Med Sci Monit 10:BR1-3. 2004
    ..This study aimed to assess a novel, rapid, computerized method for assessment of SSI in a rat model of sciatic nerve injury...
  33. ncbi request reprint The cholinergic system in Down's syndrome
    Vincenzo Fodale
    Department of Neurosciences, Psychiatric and Anesthesiological Sciences, University of Messina, Policlinico Universitario G Martino, Via C Valeria, Messina, Italy
    J Intellect Disabil 10:261-74. 2006
    ....
  34. ncbi request reprint Cisplatin-induced peripheral neuropathy: neuroprotection by erythropoietin without affecting tumour growth
    Roberto Bianchi
    Mario Negri Institute of Pharmacological Research, Milan, Italy
    Eur J Cancer 43:710-7. 2007
    ..0 and 1.5 mg/kg twice a week for four weeks) was neuroprotective without influencing the effectiveness of the treatment or tumour growth. EPO thus appears to be an effective neuroprotectant that does not interfere with tumour treatment...
  35. ncbi request reprint Erythropoietin and its lost receptor
    Alessio Sturiale
    Nephrol Dial Transplant 22:1484-5. 2007