Davide Grassi

Summary

Affiliation: University of L'Aquila
Country: Italy

Publications

  1. ncbi request reprint Short-term administration of dark chocolate is followed by a significant increase in insulin sensitivity and a decrease in blood pressure in healthy persons
    Davide Grassi
    Department of Internal Medicine and Public Health, University of L Aquila, L Aquila, Italy
    Am J Clin Nutr 81:611-4. 2005
  2. ncbi request reprint Cocoa reduces blood pressure and insulin resistance and improves endothelium-dependent vasodilation in hypertensives
    Davide Grassi
    Dipartimento Internal Medicine and Public Health, University of L Aquila, Piazzale Salvatore Tommasi 1, 67100 Coppito, L Aquila, Italy
    Hypertension 46:398-405. 2005
  3. ncbi request reprint C-reactive protein: interaction with the vascular endothelium and possible role in human atherosclerosis
    Claudio Ferri
    Department of Internal Medicine and Public Health, University of L Aquila, L Aquila, Italy
    Curr Pharm Des 13:1631-45. 2007
  4. ncbi request reprint Blood pressure is reduced and insulin sensitivity increased in glucose-intolerant, hypertensive subjects after 15 days of consuming high-polyphenol dark chocolate
    Davide Grassi
    Department of Internal Medicine and Public Health, University of L Aquila, 67100 L Aquila, Italy
    J Nutr 138:1671-6. 2008
  5. doi request reprint Black tea consumption dose-dependently improves flow-mediated dilation in healthy males
    Davide Grassi
    Department of Internal Medicine and Public Health, University of L Aquila, L Aquila, Italy
    J Hypertens 27:774-81. 2009
  6. doi request reprint Protective effects of flavanol-rich dark chocolate on endothelial function and wave reflection during acute hyperglycemia
    Davide Grassi
    University of L Aquila, Department of Internal Medicine and Public Health, Viale S Salvatore, Delta 6 Medicina, 67100 Coppito, L Aquila, Italy
    Hypertension 60:827-32. 2012
  7. pmc Flavonoids: antioxidants against atherosclerosis
    Davide Grassi
    Department of Internal Medicine and Public Health, University of L Aquila, L Aquila, 67100 Italy
    Nutrients 2:889-902. 2010
  8. ncbi request reprint Cardiovascular risk and endothelial dysfunction: the preferential route for atherosclerosis
    Davide Grassi
    Department of Internal Medicine and Public Health, University of L Aquila, Viale S Salvatore, Delta 6 Medicina, 67100 Coppito L Aquila, Italy
    Curr Pharm Biotechnol 12:1343-53. 2011
  9. ncbi request reprint Flavonoids, vascular function and cardiovascular protection
    Davide Grassi
    Department of Internal Medicine and Public Health, University of L Aquila, Coppito, Italy
    Curr Pharm Des 15:1072-84. 2009
  10. ncbi request reprint Oxidative stress and endothelial dysfunction: say NO to cigarette smoking!
    Davide Grassi
    Department of Internal Medicine and Public Health, University of L Aquila, Viale S Salvatore, Delta 6 Medicina, 67100 Coppito AQ, Italy
    Curr Pharm Des 16:2539-50. 2010

Collaborators

Detail Information

Publications22

  1. ncbi request reprint Short-term administration of dark chocolate is followed by a significant increase in insulin sensitivity and a decrease in blood pressure in healthy persons
    Davide Grassi
    Department of Internal Medicine and Public Health, University of L Aquila, L Aquila, Italy
    Am J Clin Nutr 81:611-4. 2005
    ..In turn, nitric oxide bioavailability deeply influences insulin-stimulated glucose uptake and vascular tone. Thus, flavanols may also exert positive metabolic and pressor effects...
  2. ncbi request reprint Cocoa reduces blood pressure and insulin resistance and improves endothelium-dependent vasodilation in hypertensives
    Davide Grassi
    Dipartimento Internal Medicine and Public Health, University of L Aquila, Piazzale Salvatore Tommasi 1, 67100 Coppito, L Aquila, Italy
    Hypertension 46:398-405. 2005
    ..These results suggest that, while balancing total calorie intake, flavanols from cocoa products may provide some cardiovascular benefit if included as part of a healthy diet for patients with EH...
  3. ncbi request reprint C-reactive protein: interaction with the vascular endothelium and possible role in human atherosclerosis
    Claudio Ferri
    Department of Internal Medicine and Public Health, University of L Aquila, L Aquila, Italy
    Curr Pharm Des 13:1631-45. 2007
    ..Then, we have discussed how to measure circulating CRP and the more recent findings on the suggested role of circulating CRP as a novel cardiovascular risk factor...
  4. ncbi request reprint Blood pressure is reduced and insulin sensitivity increased in glucose-intolerant, hypertensive subjects after 15 days of consuming high-polyphenol dark chocolate
    Davide Grassi
    Department of Internal Medicine and Public Health, University of L Aquila, 67100 L Aquila, Italy
    J Nutr 138:1671-6. 2008
    ..These findings suggest flavanol-rich, low-energy cocoa food products may have a positive impact on CVD risk factors...
  5. doi request reprint Black tea consumption dose-dependently improves flow-mediated dilation in healthy males
    Davide Grassi
    Department of Internal Medicine and Public Health, University of L Aquila, L Aquila, Italy
    J Hypertens 27:774-81. 2009
    ..Further, no study has evaluated the dose-response curve. Our study aimed to test the effects of various doses of black tea on vascular function, BP and insulin resistance...
  6. doi request reprint Protective effects of flavanol-rich dark chocolate on endothelial function and wave reflection during acute hyperglycemia
    Davide Grassi
    University of L Aquila, Department of Internal Medicine and Public Health, Viale S Salvatore, Delta 6 Medicina, 67100 Coppito, L Aquila, Italy
    Hypertension 60:827-32. 2012
    ..These results suggest cocoa flavanols may contribute to vascular health by reducing the postprandial impairment of arterial function associated with the pathogenesis of atherosclerosis...
  7. pmc Flavonoids: antioxidants against atherosclerosis
    Davide Grassi
    Department of Internal Medicine and Public Health, University of L Aquila, L Aquila, 67100 Italy
    Nutrients 2:889-902. 2010
    ..Dietary flavonoids represent a range of polyphenolic compounds naturally occurring in plant foods. Flavonoids are potentially involved in cardiovascular prevention mainly by decreasing oxidative stress and increasing NO bioavailability...
  8. ncbi request reprint Cardiovascular risk and endothelial dysfunction: the preferential route for atherosclerosis
    Davide Grassi
    Department of Internal Medicine and Public Health, University of L Aquila, Viale S Salvatore, Delta 6 Medicina, 67100 Coppito L Aquila, Italy
    Curr Pharm Biotechnol 12:1343-53. 2011
    ..The concepts of "endothelial dysfunction" and "endothelial activation" referring to different alterations in endothelial phenotype, may contribute to the development and clinical expression of atherosclerosis...
  9. ncbi request reprint Flavonoids, vascular function and cardiovascular protection
    Davide Grassi
    Department of Internal Medicine and Public Health, University of L Aquila, Coppito, Italy
    Curr Pharm Des 15:1072-84. 2009
    ....
  10. ncbi request reprint Oxidative stress and endothelial dysfunction: say NO to cigarette smoking!
    Davide Grassi
    Department of Internal Medicine and Public Health, University of L Aquila, Viale S Salvatore, Delta 6 Medicina, 67100 Coppito AQ, Italy
    Curr Pharm Des 16:2539-50. 2010
    ....
  11. doi request reprint Blood pressure and cardiovascular risk: what about cocoa and chocolate?
    Davide Grassi
    Department of Internal Medicine and Public Health, University of L Aquila, L Aquila, Italy
    Arch Biochem Biophys 501:112-5. 2010
    ..Cocoa consumption could play a pivotal role in human health...
  12. ncbi request reprint Tea, flavonoids, and nitric oxide-mediated vascular reactivity
    Davide Grassi
    Department of Internal Medicine and Public Health, University of L Aquila, 67100 L Aquila, Italy
    J Nutr 138:1554S-1560S. 2008
    ..Thus, because tea is a popular beverage worldwide, and several studies have shown that it is protective against CVD, further studies are needed to determine the role of tea in primary and secondary cardiovascular prevention...
  13. doi request reprint Benefits in cognitive function, blood pressure, and insulin resistance through cocoa flavanol consumption in elderly subjects with mild cognitive impairment: the Cocoa, Cognition, and Aging (CoCoA) study
    Giovambattista Desideri
    University of L Aquila, Department of Life, Health, and Environmental Sciences, Viale S Salvatore, Delta 6 Medicina, 67100 Coppito, L Aquila, Italy
    Hypertension 60:794-801. 2012
    ..This effect appears mediated in part by an improvement in insulin sensitivity...
  14. pmc Different effects of angiotensin converting enzyme inhibitors on endothelin-1 and nitric oxide balance in human vascular endothelial cells: evidence of an oxidant-sensitive pathway
    Giovambattista Desideri
    Department of Internal Medicine and Public Health, University of L Aquila, Piazzale S Tommasi 1, 67100 Coppito, L Aquila, Italy
    Mediators Inflamm 2008:305087. 2008
    ..In conclusion, among the four tested ACE-I, zofenoprilat was more effective in improving endothelin-1/nitric oxide balance in HUVECs likely because of its greater antioxidant properties...
  15. ncbi request reprint Enhanced plasma soluble CD40 ligand levels in essential hypertensive patients with blunted nocturnal blood pressure decrease
    Giovambattista Desideri
    Department of Internal Medicine and Public Health, University of L Aquila, Piazzale Salvatore Tommasi 1, 67100 Coppito, L Aquila, Italy
    Am J Hypertens 20:70-6; discussion 77. 2007
    ..Therefore, we evaluated the relationship between circulating sCD40L levels, circadian BP profile, and early carotid atherosclerosis in essential hypertensives...
  16. doi request reprint Soluble CD40 ligand is predictive of combined cardiovascular morbidity and mortality in patients on haemodialysis at a relatively short-term follow-up
    Giovambattista Desideri
    Department of Internal Medicine and Public Health, University of L Aquila, L Aquila, Italy
    Nephrol Dial Transplant 26:2983-8. 2011
    ....
  17. ncbi request reprint Cardiovascular risk and cardiometabolic protection: role of glitazones
    Luisa Petrazzi
    Department of Internal Medicine and Public Health, University of L Aquila, L Aquila Italy
    J Nephrol 21:826-35. 2008
    ..Additional large-scale trials are awaited to clarify the of role TZDs in cardiovascular outcomes...
  18. pmc Chronic hyperuricemia, uric acid deposit and cardiovascular risk
    Davide Grassi
    University of L Aquila Department of Internal Medicine and Public Health San Salvatore Hospital Italy
    Curr Pharm Des 19:2432-8. 2013
    ..The value of uric acid as a biomarker and as a potential therapeutic target for tailored old and novel "cardiometabolic" treatments will be also discussed...
  19. doi request reprint Endothelium/nitric oxide mechanism mediates vasorelaxation and counteracts vasoconstriction induced by low concentration of flavanols
    Annalisa Aggio
    Department of Internal Medicine and Public Health, University of L Aquila, Viale S Salvatore, Delta 6 Medicina, 67100, Coppito, AQ, Italy
    Eur J Nutr 52:263-72. 2013
    ..The aim of our study was to investigate the effects of two flavanols at different doses on arterial functional state...
  20. ncbi request reprint Cognitive decline as a consequence of essential hypertension
    Davide Grassi
    Department of Internal Medicine and Public Health, University of L Aquila, L Aquila, Italy
    Curr Pharm Des 17:3032-8. 2011
    ..New randomized controlled trials are needed to definitively clarify clinical advantages and specifically elucidate the relationship between anti-hypertensive treatments and cognitive function or dementia...
  21. doi request reprint Enhanced proatherogenic inflammation after recombinant human TSH administration in patients monitored for thyroid cancer remnant
    Giovambattista Desideri
    Department of Internal Medicine and Public Health, University of L Aquila, Italy
    Clin Endocrinol (Oxf) 71:429-33. 2009
    ..To evaluate the effect of recombinant human TSH (rhTSH) on biomarkers of vascular endothelial cell and platelet activation in patients monitored for thyroid carcinoma remnant...
  22. ncbi request reprint Cocoa beans, endothelial function and aging: an unexpected friendship?
    Claudio Ferri
    J Hypertens 24:1471-4. 2006