Stefano Gonnelli

Summary

Affiliation: University of Siena
Country: Italy

Publications

  1. doi request reprint Effects of intravenous zoledronate and ibandronate on carotid intima-media thickness, lipids and FGF-23 in postmenopausal osteoporotic women
    S Gonnelli
    Department of Medicine, Surgery and Neuroscience, University of Siena, Italy Electronic address
    Bone 61:27-32. 2014
  2. doi request reprint Relationship between quantitative ultrasound parameters at the calcaneus and health-related quality of life in postmenopausal italian women: the FEDRO study
    Stefano Gonnelli
    Department of Internal Medicine, Endocrine Metabolic Science and Biochemistry, University of Siena, Policlinico Le Scotte, Viale Bracci 2, 53100, Siena, Italy
    Calcif Tissue Int 93:487-94. 2013
  3. doi request reprint New-onset hypercholesterolemia as an unusual presenting manifestation of eosinophilic gastroenteritis
    Stefano Gonnelli
    Department of Internal Medicine, Endocrine Metabolic Science and Biochemistry, University of Siena, Policlinico Le Scotte, Viale Bracci 2, 53100 Siena, Italy
    J Clin Lipidol 7:229-33. 2013
  4. doi request reprint The associations of body composition and fat distribution with bone mineral density in elderly Italian men and women
    Stefano Gonnelli
    Department of Internal Medicine, Endocrine Metabolic Science and Biochemistry, University of Siena, Siena, Italy
    J Clin Densitom 16:168-77. 2013
  5. doi request reprint The assessment of vertebral fractures in elderly women with recent hip fractures: the BREAK Study
    S Gonnelli
    Department of Internal Medicine, Endocrine Metabolic Science and Biochemistry, University of Siena, Policlinico Le Scotte, Viale Bracci 2, 53100, Siena, Italy
    Osteoporos Int 24:1151-9. 2013
  6. ncbi request reprint Changes in bone turnover and in bone mass in women with breast cancer switched from tamoxifen to exemestane
    S Gonnelli
    Department of Internal Medicine, Endocrine Metabolic Science and Biochemistry, University of Siena, Policlinico Le Scotte, Viale Bracci 2, 53100 Siena, Italy
    Bone 40:205-10. 2007
  7. ncbi request reprint Teriparatide's effects on quantitative ultrasound parameters and bone density in women with established osteoporosis
    S Gonnelli
    Department of Internal Medicine, Endocrine Metabolic Science and Biochemistry, University of Siena Policlinico Le Scotte, Viale Bracci 2, 53100, Siena, Italy
    Osteoporos Int 17:1524-31. 2006
  8. ncbi request reprint Osteoprotegerin (OPG) and receptor activator of NF-kB ligand (RANK-L) serum levels in patients on chronic hemodialysis
    S Gonnelli
    Department of Internal Medicine, Endocrine Metabolic Sciences and Biochemistry, University of Siena, Siena, Italy
    J Endocrinol Invest 28:534-9. 2005
  9. ncbi request reprint Quantitative ultrasound and dual-energy X-ray absorptiometry in the prediction of fragility fracture in men
    Stefano Gonnelli
    Department of Internal Medicine, Endocrine Metabolic Science and Biochemistry, University of Siena, Policlinico Le Scotte, Viale Bracci 2, 53100 Siena, Italy
    Osteoporos Int 16:963-8. 2005
  10. ncbi request reprint Usefulness of QUS in follow-up
    Stefano Gonnelli
    Department of Internal Medicine, Endocrine Metabolic Science and Biochemistry, University of Siena, Policlinico Le Scote, Siena, Italy
    Aging Clin Exp Res 19:15-7. 2007

Detail Information

Publications44

  1. doi request reprint Effects of intravenous zoledronate and ibandronate on carotid intima-media thickness, lipids and FGF-23 in postmenopausal osteoporotic women
    S Gonnelli
    Department of Medicine, Surgery and Neuroscience, University of Siena, Italy Electronic address
    Bone 61:27-32. 2014
    ..This study aimed to evaluate the effects of one year with zoledronate or ibandronate given intravenously on lipid profile and on carotid artery intima-media thickness (CA-IMT)...
  2. doi request reprint Relationship between quantitative ultrasound parameters at the calcaneus and health-related quality of life in postmenopausal italian women: the FEDRO study
    Stefano Gonnelli
    Department of Internal Medicine, Endocrine Metabolic Science and Biochemistry, University of Siena, Policlinico Le Scotte, Viale Bracci 2, 53100, Siena, Italy
    Calcif Tissue Int 93:487-94. 2013
    ..Therefore, QUS at the calcaneus may have a role in early strategies to prevent HRQoL impairment and osteoporosis exacerbation...
  3. doi request reprint New-onset hypercholesterolemia as an unusual presenting manifestation of eosinophilic gastroenteritis
    Stefano Gonnelli
    Department of Internal Medicine, Endocrine Metabolic Science and Biochemistry, University of Siena, Policlinico Le Scotte, Viale Bracci 2, 53100 Siena, Italy
    J Clin Lipidol 7:229-33. 2013
    ..The patient has been successfully treated with prednisone and budesonide. Hypercholesterolemia may be an early manifestation of a serious underlying disease, among which eosinophilic gastroenteritis should also be considered...
  4. doi request reprint The associations of body composition and fat distribution with bone mineral density in elderly Italian men and women
    Stefano Gonnelli
    Department of Internal Medicine, Endocrine Metabolic Science and Biochemistry, University of Siena, Siena, Italy
    J Clin Densitom 16:168-77. 2013
    ..In conclusion, the role of LM seems more important in males, whereas in women the role of FM prevails with negative associations between gynoid fat and BMD...
  5. doi request reprint The assessment of vertebral fractures in elderly women with recent hip fractures: the BREAK Study
    S Gonnelli
    Department of Internal Medicine, Endocrine Metabolic Science and Biochemistry, University of Siena, Policlinico Le Scotte, Viale Bracci 2, 53100, Siena, Italy
    Osteoporos Int 24:1151-9. 2013
    ..The burden of vertebral fractures expressed by the Spinal Deformity Index (SDI) is more strictly associated with the trochanteric than the cervical localization of hip fracture and may influence short-term functional outcomes...
  6. ncbi request reprint Changes in bone turnover and in bone mass in women with breast cancer switched from tamoxifen to exemestane
    S Gonnelli
    Department of Internal Medicine, Endocrine Metabolic Science and Biochemistry, University of Siena, Policlinico Le Scotte, Viale Bracci 2, 53100 Siena, Italy
    Bone 40:205-10. 2007
    ..Therefore, the postmenopausal women switched from tamoxifen to exemestane should be monitored for bone loss especially if other risk factors for osteoporosis are present...
  7. ncbi request reprint Teriparatide's effects on quantitative ultrasound parameters and bone density in women with established osteoporosis
    S Gonnelli
    Department of Internal Medicine, Endocrine Metabolic Science and Biochemistry, University of Siena Policlinico Le Scotte, Viale Bracci 2, 53100, Siena, Italy
    Osteoporos Int 17:1524-31. 2006
    ....
  8. ncbi request reprint Osteoprotegerin (OPG) and receptor activator of NF-kB ligand (RANK-L) serum levels in patients on chronic hemodialysis
    S Gonnelli
    Department of Internal Medicine, Endocrine Metabolic Sciences and Biochemistry, University of Siena, Siena, Italy
    J Endocrinol Invest 28:534-9. 2005
    ..39) no relationship was found. In conclusion, our findings showed that, although both OPG and RANK-L are accumulated in hemodialysis patients, only RANK-L and the balance between OPG and RANK-L seem to be related to osteoclast activity...
  9. ncbi request reprint Quantitative ultrasound and dual-energy X-ray absorptiometry in the prediction of fragility fracture in men
    Stefano Gonnelli
    Department of Internal Medicine, Endocrine Metabolic Science and Biochemistry, University of Siena, Policlinico Le Scotte, Viale Bracci 2, 53100 Siena, Italy
    Osteoporos Int 16:963-8. 2005
    ..QUS seems to play an independent and complementary role, with respect to DXA, in order to enhance the power for predicting osteoporotic fractures in men...
  10. ncbi request reprint Usefulness of QUS in follow-up
    Stefano Gonnelli
    Department of Internal Medicine, Endocrine Metabolic Science and Biochemistry, University of Siena, Policlinico Le Scote, Siena, Italy
    Aging Clin Exp Res 19:15-7. 2007
    ..If the results are confirmed by further investigations QUS may represent an important non-invasive tool for a more comprehensive investigation of the skeletal effects of therapeutic interventions and particularly the anabolic agents...
  11. doi request reprint Bone ultrasonography at phalanxes in patients with Rett syndrome: a 3-year longitudinal study
    S Gonnelli
    Department of Internal Medicine, Endocrine Metabolic Science and Biochemistry, University of Siena, Policlinico Le Scotte, Viale Bracci 2, 53100 Siena, Italy
    Bone 42:737-42. 2008
    ..In conclusion our results suggest the usefulness of QUS parameters at phalanxes in the monitoring of bone status in Rett patients. Low levels of 25OHD and ambulatory impairment play a key role in the skeletal deterioration in Rett girls...
  12. doi request reprint The relationship of ghrelin and adiponectin with bone mineral density and bone turnover markers in elderly men
    S Gonnelli
    Department of Internal Medicine, Endocrine Metabolic Science and Biochemistry, University of Siena, Policlinico Le Scotte, Viale Bracci 2, 53100, Siena, Italy
    Calcif Tissue Int 83:55-60. 2008
    ..Further studies are needed to elucidate the role of adipocytokines in bone metabolism...
  13. pmc Aromatase inhibitors, efficacy and metabolic risk in the treatment of postmenopausal women with early breast cancer
    Stefano Gonnelli
    Department of Internal Medicine, Endocrine Metabolic Science and Biochemistry, University of Siena, Policlinico Le Scotte, Viale Bracci 2, 53100 Siena, Italy
    Clin Interv Aging 3:647-57. 2008
    ..An adequate monitoring of bone mineral density (BMD) and lipid profile could be recommended for post-menopausal women candidate to AIs...
  14. doi request reprint Effect of inhaled glucocorticoids and beta(2) agonists on vertebral fracture risk in COPD patients: the EOLO study
    S Gonnelli
    Department of Internal Medicine, Endocrine Metabolic Science, and Biochemistry, University of Siena, Policlinico Le Scotte, Viale Bracci 2, 53100 Siena, Italy
    Calcif Tissue Int 87:137-43. 2010
    ..28, and OR = 1.40, CI 1.06-1.82, respectively). In conclusion, in COPD patients high doses of inhaled GCs, but not beta(2) agonists, are associated with an increased risk of vertebral fractures and a reduction of QUS at the calcaneus...
  15. doi request reprint The association of body composition and sex hormones with quantitative ultrasound parameters at the calcaneus and phalanxes in elderly women
    S Gonnelli
    Department of Internal Medicine, Endocrine Metabolic Science and Biochemistry, University of Siena, Policlinico Le Scotte, Italy
    Calcif Tissue Int 89:456-63. 2011
    ..In postmenopausal women QUS parameters at the calcaneus and at phalanxes are significantly, but diversely, associated with body composition, sex hormones, 25OHD, and bone turnover markers...
  16. ncbi request reprint Calcium bioavailability from a new calcium-fortified orange beverage, compared with milk, in healthy volunteers
    Stefano Gonnelli
    Department of Internal Medicine, Endocrine Metabolic Sciences and Biochemistry, University of Siena, Italy
    Int J Vitam Nutr Res 77:249-54. 2007
    ..1 +/- 14.0% for milk and -27.9 +/- 15.3% for orange beverage). We can conclude that the bioavailability of calcium from this new calcium-enriched orange beverage is similar to that of milk...
  17. ncbi request reprint Heel ultrasonography in monitoring alendronate therapy: a four-year longitudinal study
    S Gonnelli
    Institute of Internal Medicine, University of Siena, Italy
    Osteoporos Int 13:415-21. 2002
    ..2 years for BMD, SOS, BUA and Stiffness respectively. Therefore, although the spinal BMD remains the optimal method, QUS at the heel, and in particular Stiffness, seems to be a sensitive tool for monitoring the response to alendronate...
  18. ncbi request reprint Feasibility of quantitative ultrasound measurements on the humerus of newborn infants for the assessment of the skeletal status
    S Gonnelli
    Department of Internal Medicine, Metabolic and Endocrinological Science and Biochemistry, Policlinico Le Scotte, University of Siena, Viale Bracci, 53100 Siena, Italy
    Osteoporos Int 15:541-6. 2004
    ..BTT and, above all, hBTT, appears to be the best parameter for both evaluation of skeletal status at birth and monitoring of bone growth in the first year of life...
  19. ncbi request reprint Alendronate treatment in men with primary osteoporosis: a three-year longitudinal study
    S Gonnelli
    Department of Internal Medicine, Endocrine Metabolic Science and Biochemistry, University of Siena, Italy
    Calcif Tissue Int 73:133-9. 2003
    ..BMD at the lumbar spine appears to be the best method for monitoring the effect of alendronate on bone mass in osteoporotic men...
  20. ncbi request reprint The use of ultrasound in the assessment of bone status
    S Gonnelli
    Institute of Internal Medicine, University of Siena, Italy
    J Endocrinol Invest 25:389-97. 2002
    ....
  21. ncbi request reprint Quantitative ultrasound and bone mineral density in patients with primary hyperparathyroidism before and after surgical treatment
    S Gonnelli
    Institute of Internal Medicine, University of Siena, Italy
    Osteoporos Int 11:255-60. 2000
    ..The combined use of BMD and QUS could improve the assessment of skeletal status in patients with PHPT before and after surgery...
  22. doi request reprint Accuracy of different reduced versions of a validated food-frequency questionnaire in italian men and women
    S Gonnelli
    Department of Internal Medicine, Endocrine Metabolic Science and Biochemistry, University of Siena, Policlinico Le Scotte, Viale Bracci 2, 53100, Siena, Italy
    Calcif Tissue Int 85:221-7. 2009
    ..ROC analysis and posttest probability calculated by positive likelihood ratio may represent an optimal method for assessing the accuracy of FFQs...
  23. ncbi request reprint Longitudinal association between sex hormone levels, bone loss, and bone turnover in elderly men
    Luigi Gennari
    Department of Internal Medicine, Endocrine Metabolic Sciences and Biochemistry, University of Siena, 53100 Siena, Italy
    J Clin Endocrinol Metab 88:5327-33. 2003
    ..In conclusion, results from the present study indicate an important role of estrogens, and particularly of the ability to aromatize T to E(2), in the regulation of bone loss and bone metabolism in elderly men...
  24. ncbi request reprint In vivo performance evaluation of the Achilles Insight QUS device
    Chiara Cepollaro
    Department of Internal Medicine, Endocrine Metabolic Science and Biochemistry, University of Siena, Siena, Italy
    J Clin Densitom 8:341-6. 2005
    ..The high correlation and the similar ability to identify postmenopausal women with vertebral fracture suggest the possibility of using the database of Achilles plus for Achilles Insight...
  25. doi request reprint Quantitative ultrasound and dual-energy x-ray absorptiometry in children and adolescents with neurofibromatosis of type 1
    Carla Caffarelli
    Department of Internal Medicine, Endocrine Metabolic Science and Biochemistry, University of Siena, Siena, Italy
    J Clin Densitom 13:77-83. 2010
    ..In conclusion, our results suggest that aBMD and QUS represent useful tools in evaluating the impairment of bone status in NF1 subjects...
  26. ncbi request reprint A polymorphic CYP19 TTTA repeat influences aromatase activity and estrogen levels in elderly men: effects on bone metabolism
    Luigi Gennari
    Department of Internal Medicine, University of Florence, 50139 Florence, Italy
    J Clin Endocrinol Metab 89:2803-10. 2004
    ..In conclusion, differences in estrogen levels due to polymorphism at the aromatase CYP19 gene may predispose men to increased age-related bone loss and fracture risk...
  27. ncbi request reprint Osteoporosis and risk of fracture in patients with diabetes: an update
    Andrea Montagnani
    Metabolic Bone Diseases and Osteoporosis Unit, Department of Internal Medicine, Misericordia Hospital, Via Senese, Grosseto, Italy
    Aging Clin Exp Res 23:84-90. 2011
    ..Lastly, patients with osteoporosis and diabetes should be offered the same pharmacological treatments as non-diabetics, although specific trials on the effects of anti-osteoporotic drugs in the diabetic population are lacking...
  28. ncbi request reprint Dual X-ray absorptiometry and bone ultrasonography in patients with Rett syndrome
    C Cepollaro
    Institute of Internal Medicine, University of Siena, Policlinico Le Scotte, Italy
    Calcif Tissue Int 69:259-62. 2001
    ..Whatever the cause, girls with RS present abnormal bone status with an increase in the risk of fracture...
  29. ncbi request reprint 18q-syndrome and ectodermal dysplasia syndrome: description of a child and his family
    R Zannolli
    Department of Pediatrics, Obstetrics and Reproductive Medicine, Section of Pediatrics, Policlinico Le Scotte, University of Siena, Siena, Italy
    Am J Med Genet A 116:192-9. 2003
    ..Most of these abnormalities were not explained by the 18q- deletion. The family pedigree suggested the presence of a subtle involvement of ectodermal and/or mesodermal structures. Karyotypes of the other family members were normal...
  30. ncbi request reprint Urinary calcium excretion in the monitoring of bone metastases from prostatic carcinoma
    G Francini
    Medical Oncology Division, Institute of Internal Medicine, University of Siena, Siena, Italy
    Cancer 92:1468-74. 2001
    ....
  31. ncbi request reprint Usefulness of bone quantitative ultrasound in management of osteoporosis in men
    A Montagnani
    Institute of Internal Medicine, University of Siena, Policlinico Le Scotte, Viale Bracci, 53100 Siena, Italy
    J Clin Densitom 4:231-7. 2001
    ..In conclusion, our data show that QUS parameters are reduced in osteoporotic males; however, only BTT was comparable to DXA parameters in the prediction of fracture risk in men...
  32. ncbi request reprint Quantitative ultrasound in the assessment of skeletal status in uremic patients
    A Montagnani
    Institute of Internal Medicine, University of Siena, Italy
    J Clin Densitom 2:389-95. 1999
    ..Our results seem to demonstrate that US parameters are a useful tool in the assessment of skeletal status in patients on maintenance dialysis...
  33. ncbi request reprint PTH in the pathogenesis and treatment of glucocorticoid-induced osteoporosis
    C Gennari
    Institute of Internal Medicine, University of Siena, Italy
    Front Horm Res 30:184-97. 2002
  34. ncbi request reprint Graphic trace analysis of ultrasound at the phalanges may differentiate between subjects with primary hyperparathyroidism and with osteoporosis: a pilot study
    A Montagnani
    Institute of Internal Medicine, University of Siena, Policlinico Le Scotte, Italy
    Osteoporos Int 13:222-7. 2002
    ..This suggests that the QUS signal could be a useful instrument in discriminating and studying some of the bone alterations typical of metabolic bone diseases...
  35. doi request reprint The effects on lipid serum levels of a 2-year adjuvant treatment with exemestane after tamoxifen in postmenopausal women with early breast cancer
    A Montagnani
    Department of Internal Medicine, Endocrine Metabolic Sciences and Biochemistry, University of Siena, Italy
    Eur J Intern Med 19:592-7. 2008
    ..The aim of this study was to evaluate the effects on lipid profile and body composition of the shift from tamoxifen to exemestane...
  36. doi request reprint Vertebral fractures in patients with chronic obstructive pulmonary disease: the EOLO Study
    R Nuti
    Department of Internal Medicine, Endocrine Metabolic Science and Biochemistry, University of Siena, Policlinico Le Scotte, Viale Bracci 2, 53100 Siena, Italy
    Osteoporos Int 20:989-98. 2009
    ..The risk of vertebral fractures is strictly related to the severity of the disease. The use of glucocorticoids and the presence of low values of quantitative ultrasound (QUS) may represent additional risk factors...
  37. ncbi request reprint Malignant hypercalcemia in vulvar cancer
    R Bilenchi
    Department of Clinical Medicine and Immunological Sciences, University of Siena, Siena, Italy
    Minerva Ginecol 57:569-74. 2005
    ..To our knowledge, this is the first documented case with high serum concentrations of PTHrP and immunohistochemical confirmation of PTHrP production by neoplastic cells...
  38. ncbi request reprint Bone ultrasonography in glucocorticoid-induced osteoporosis
    C Cepollaro
    Department of Internal Medicine, Endocrine Metabolic Science and Biochemistry, University of Siena, Siena, Italy
    Osteoporos Int 16:743-8. 2005
    ..Further longitudinal studies are needed to define the role of QUS in the prediction of fracture risk and in the clinical management of GIO...
  39. ncbi request reprint Effect of simvastatin treatment on bone mineral density and bone turnover in hypercholesterolemic postmenopausal women: a 1-year longitudinal study
    A Montagnani
    Department of Internal Medicine, University of Siena, Italy
    Bone 32:427-33. 2003
    ..05) for both BMD-LS and BMD-Fn only at Month 12. In conclusion our results, although obtained from a small sample of postmenopausal hypercholesterolemic women, suggest a probable positive effect of simvastatin on bone formation and BMD...
  40. ncbi request reprint Changes in serum HDL and LDL cholesterol in patients with Paget's bone disease treated with pamidronate
    A Montagnani
    Institute of Internal Medicine, Policlinico Le Scotte, University of Siena, Viale Bracci, 53100 Siena, Italy
    Bone 32:15-9. 2003
    ....
  41. pmc Exemestane after tamoxifen as adjuvant hormonal therapy in postmenopausal women with breast cancer: effects on body composition and lipids
    G Francini
    Department of Human Pathology and Oncology, Medical Oncology Section, University of Siena, Siena, Italy
    Br J Cancer 95:153-8. 2006
    ..Our findings suggest that switching patients to adjuvant exemestane treatment after at least 2 years of tamoxifen therapy may be associated with an advantage over continuing adjuvant tamoxifen treatment in terms of body composition...
  42. pmc Implementing adherence to osteoporosis treatments
    Stefano Gonnelli
    Department of Internal Medicine, Endocrine Metabolic Science and Biochemistry, University of Siena, Italy
    Clin Cases Miner Bone Metab 6:193-6. 2009
    ..These findings underline the key role played by the physicians, above all GPs, in a strategy to improve adherence which now could be supported by the avaibility of new drugs and innovative administration routes...
  43. ncbi request reprint Validation of a food frequency questionnaire for nutritional calcium intake assessment in Italian women
    M Montomoli
    Institute of Internal Medicine, State University of Siena, Siena, Italy
    Eur J Clin Nutr 56:21-30. 2002
    ..To evaluate a food frequency questionnaire assessing calcium intake in women...
  44. doi request reprint Quantitative ultrasound in the management of osteoporosis: the 2007 ISCD Official Positions
    Marc Antoine Krieg
    Lausanne University Hospital, Lausanne, Switzerland
    J Clin Densitom 11:163-87. 2008
    ..The ISCD Official Positions on QUS resulting from this PDC, the rationale for their establishment, and recommendations for further study are presented here...