Stefania Gonfloni

Summary

Affiliation: University of Rome Tor Vergata
Country: Italy

Publications

  1. ncbi request reprint Inhibition of the c-Abl-TAp63 pathway protects mouse oocytes from chemotherapy-induced death
    Stefania Gonfloni
    Department of Biology, University of Rome Tor Vergata, Rome, Italy
    Nat Med 15:1179-85. 2009
  2. ncbi request reprint DNA damage stress response in germ cells: role of c-Abl and clinical implications
    S Gonfloni
    Department of Biology, University of Rome, Tor Vergata, Rome, Italy
    Oncogene 29:6193-202. 2010
  3. ncbi request reprint P53 and Sirt1: routes of metabolism and genome stability
    Stefania Gonfloni
    Department of Biology, University of Rome Tor Vergata, Via della Ricerca Scientifica, 00133 Rome, Italy Laboratoire de Biologie Mol├ęculaire et Cellulaire du Cancer, Kirchberg Hospital, 9 rue Edward Steichen, 2540 Luxembourg, Luxembourg Electronic address
    Biochem Pharmacol 92:149-56. 2014
  4. pmc Oxidative Stress, DNA Damage, and c-Abl Signaling: At the Crossroad in Neurodegenerative Diseases?
    Stefania Gonfloni
    Department of Biology, University of Rome Tor Vergata, Via della Ricerca Scientifica, 00133 Rome, Italy
    Int J Cell Biol 2012:683097. 2012
  5. ncbi request reprint Targeting DNA damage response: threshold, chromatin landscape and beyond
    Stefania Gonfloni
    Department of Biology, University of Rome Tor Vergata, Via della Ricerca Scientifica, I 00133 Rome, Italy
    Pharmacol Ther 138:46-52. 2013
  6. pmc Parkinson’S disease: a complex interplay of mitochondrial DNA alterations and oxidative stress
    Sarah Ciccone
    Department of Biology, University of Rome Tor Vergata, Via della Ricerca Scientifica, 00133 Rome, Italy
    Int J Mol Sci 14:2388-409. 2013
  7. ncbi request reprint DNA damage response: the emerging role of c-Abl as a regulatory switch?
    Emiliano Maiani
    Department of Biology, University of Rome Tor Vergata, Via della Ricerca Scientifica, I 00133 Rome, Italy
    Biochem Pharmacol 82:1269-76. 2011

Collaborators

Detail Information

Publications7

  1. ncbi request reprint Inhibition of the c-Abl-TAp63 pathway protects mouse oocytes from chemotherapy-induced death
    Stefania Gonfloni
    Department of Biology, University of Rome Tor Vergata, Rome, Italy
    Nat Med 15:1179-85. 2009
    ..Moreover, they suggest a new use for imatinib, aimed at preserving oocytes of the follicle reserve during chemotherapeutic treatments...
  2. ncbi request reprint DNA damage stress response in germ cells: role of c-Abl and clinical implications
    S Gonfloni
    Department of Biology, University of Rome, Tor Vergata, Rome, Italy
    Oncogene 29:6193-202. 2010
    ....
  3. ncbi request reprint P53 and Sirt1: routes of metabolism and genome stability
    Stefania Gonfloni
    Department of Biology, University of Rome Tor Vergata, Via della Ricerca Scientifica, 00133 Rome, Italy Laboratoire de Biologie Mol├ęculaire et Cellulaire du Cancer, Kirchberg Hospital, 9 rue Edward Steichen, 2540 Luxembourg, Luxembourg Electronic address
    Biochem Pharmacol 92:149-56. 2014
    ..In this review, we will focus on the interplay between p53 and SIRT1. We will discuss their roles as nodes for possible therapeutic intervention. ..
  4. pmc Oxidative Stress, DNA Damage, and c-Abl Signaling: At the Crossroad in Neurodegenerative Diseases?
    Stefania Gonfloni
    Department of Biology, University of Rome Tor Vergata, Via della Ricerca Scientifica, 00133 Rome, Italy
    Int J Cell Biol 2012:683097. 2012
    ..Finally, we propose that this may have an impact in the development of new therapeutic strategies...
  5. ncbi request reprint Targeting DNA damage response: threshold, chromatin landscape and beyond
    Stefania Gonfloni
    Department of Biology, University of Rome Tor Vergata, Via della Ricerca Scientifica, I 00133 Rome, Italy
    Pharmacol Ther 138:46-52. 2013
    ..This review focuses on the interplay between histone modifications and the chromatin-mediated response to DNA damage...
  6. pmc Parkinson’S disease: a complex interplay of mitochondrial DNA alterations and oxidative stress
    Sarah Ciccone
    Department of Biology, University of Rome Tor Vergata, Via della Ricerca Scientifica, 00133 Rome, Italy
    Int J Mol Sci 14:2388-409. 2013
    ..This review focuses on recently described networks most likely involved in an integrated manner in the course of PD...
  7. ncbi request reprint DNA damage response: the emerging role of c-Abl as a regulatory switch?
    Emiliano Maiani
    Department of Biology, University of Rome Tor Vergata, Via della Ricerca Scientifica, I 00133 Rome, Italy
    Biochem Pharmacol 82:1269-76. 2011
    ..However, a fine-tuning of nuclear outcomes, through pharmacological inhibition of c-Abl, may provide novel paradigms for DDR and, potentially, therapeutic strategies for cancer treatment...