Affiliation: University of Florence
Sticchi E, Giusti B, Cordisco A, Gori A, Sereni A, Sofi F, et al
. Role of lipoprotein (a) and LPA KIV2 repeat polymorphism in bicuspid aortic valve stenosis and calcification: a proof of concept study. Intern Emerg Med. 2018;: pubmed publisher
..043] were also found. In conclusion, present data suggest the potential role for Lp(a) as a possible risk marker useful to stratify, among BAV patients, those with a higher chance to develop valvular calcifications and aortic stenosis. ..
Giusti B, Galora S, Saracini C, Pratesi G, Gensini G, Pulli R, et al
. Role of rs1466535 low density lipoprotein receptor-related protein 1 (LRP1) gene polymorphism in carotid artery disease. Atherosclerosis. 2014;237:135-7 pubmed publisher
..Our result suggests this polymorphism in the LRP1 gene is not associated with atherosclerosis in general as it is not associated with CAS (this study), whereas it is strictly associated with AAA (our previous paper). ..
Giusti B, Marini M, Rossi L, Lapini I, Magi A, Capalbo A, et al
. Gene expression profile of rat left ventricles reveals persisting changes following chronic mild exercise protocol: implications for cardioprotection. BMC Genomics. 2009;10:342 pubmed publisher
Magi A, D Aurizio R, Palombo F, Cifola I, Tattini L, Semeraro R, et al
. Characterization and identification of hidden rare variants in the human genome. BMC Genomics. 2015;16:340 pubmed publisher
..For this reason, also future resequencing experiments, based on GRCh38, will benefit from RAREVATOR analysis results. RAREVATOR is freely available at http://sourceforge.net/projects/rarevator . ..
Giusti B, Gori A, Marcucci R, Abbate R. Relation of CYP2C19 loss-of-function polymorphism to the occurrence of stent thrombosis. Expert Opin Drug Metab Toxicol. 2010;6:393-407 pubmed publisher
Giusti B, Gori A, Marcucci R, Sestini I, Saracini C, Paniccia R, et al
. Role of glycoprotein Ia gene polymorphisms in determining platelet function in myocardial infarction patients undergoing percutaneous coronary intervention on dual antiplatelet treatment. Atherosclerosis. 2008;196:341-8 pubmed
Giusti B, Gori A, Marcucci R, Sestini I, Saracini C, Sticchi E, et al
. Role of C677T and A1298C MTHFR, A2756G MTR and -786 C/T eNOS gene polymorphisms in atrial fibrillation susceptibility. PLoS ONE. 2007;2:e495 pubmed
..8 (1.68-4.54 95%CI) in Q2 to 12.9 (7.96-21.06 95%CI) in Q4. Our data demonstrated the four polymorphisms, although able, at least in part, to affect Hcy, were not associated with an increased risk of NVAF per se or in combination. ..
Giusti B, Sestini I, Saracini C, Sticchi E, Bolli P, Magi A, et al
. High-throughput multiplex single-nucleotide polymorphism (SNP) analysis in genes involved in methionine metabolism. Biochem Genet. 2008;46:406-23 pubmed publisher
..2% concordance. We also performed a haplotype analysis. This approach could represent a useful tool to investigate the genotype-phenotype correlation and the association of these genes with hyperhomocysteinemia and correlated diseases. ..
Giusti B, Rossi L, Lapini I, Magi A, Pratesi G, Lavitrano M, et al
. Gene expression profiling of peripheral blood in patients with abdominal aortic aneurysm. Eur J Vasc Endovasc Surg. 2009;38:104-12 pubmed publisher
..Our data underline the power of microarrays in identifying further molecular perturbations associated with AAA. ..