Roberto De Giorgio
Affiliation: University of Bologna
De Giorgio R, Giancola F, Boschetti E, Abdo H, Lardeux B, Neunlist M. Enteric glia and neuroprotection: basic and clinical aspects. Am J Physiol Gastrointest Liver Physiol. 2012;303:G887-93 pubmed publisher
..Additional studies on EGC neuroprotective capacity are expected to improve knowledge of gut diseases and pave the way for targeted therapeutic strategies of underlying neuropathies. ..
Volta U, Caio G, De Giorgio R, Henriksen C, Skodje G, Lundin K. Non-celiac gluten sensitivity: a work-in-progress entity in the spectrum of wheat-related disorders. Best Pract Res Clin Gastroenterol. 2015;29:477-91 pubmed publisher
..Although currently limited to a research setting, double-blind, placebo-controlled, cross-over trial strategy is recommended to confirm the diagnosis. Treatment is based on dietary restriction with special care to nutrient intake. ..
Bianco F, Bonora E, Natarajan D, Vargiolu M, Thapar N, Torresan F, et al
. Prucalopride exerts neuroprotection in human enteric neurons. Am J Physiol Gastrointest Liver Physiol. 2016;310:G768-75 pubmed publisher
..Our data pave the way for novel therapeutic implications of full 5-HT4 agonists in gut dysmotility characterized by neuronal degeneration, which go beyond the well-known enterokinetic effect. ..
Volta U, Caio G, Boschetti E, Giancola F, Rhoden K, Ruggeri E, et al
. Seronegative celiac disease: Shedding light on an obscure clinical entity. Dig Liver Dis. 2016;48:1018-22 pubmed publisher
De Giorgio R, Bianco F, Latorre R, Caio G, Clavenzani P, Bonora E. Enteric neuropathies: Yesterday, Today and Tomorrow. Adv Exp Med Biol. 2016;891:123-33 pubmed publisher
De Giorgio R, Pironi L, Rinaldi R, Boschetti E, Caporali L, Capristo M, et al
. Liver transplantation for mitochondrial neurogastrointestinal encephalomyopathy. Ann Neurol. 2016;80:448-55 pubmed publisher
..Serum levels of toxic nucleosides rapidly normalized. At 400 days of follow-up, the patient's clinical conditions are stable. We propose liver transplantation as a new therapy for MNGIE. Ann Neurol 2016;80:448-455. ..
De Giorgio R, Ricciardiello L, Naponelli V, Selgrad M, Piazzi G, Felicani C, et al
. Chronic intestinal pseudo-obstruction related to viral infections. Transplant Proc. 2010;42:9-14 pubmed publisher
..The review thus provides some new perspectives in the pathophysiology and perhaps targeted treatment of CIIPO. ..
Bonora E, Bianco F, Cordeddu L, Bamshad M, Francescatto L, Dowless D, et al
. Mutations in RAD21 disrupt regulation of APOB in patients with chronic intestinal pseudo-obstruction. Gastroenterology. 2015;148:771-782.e11 pubmed publisher
..Reduced expression of rad21 in zebrafish, and dysregulation of these target genes, disrupts intestinal transit and the development of enteric neurons. ..