Research Topics
Genomes and GenesSpecies | N GiordanoSummaryAffiliation: University of Siena Country: Italy Publications
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Detail Information
Publications
Expression of RXFP1 in skin of scleroderma patients and control subjectsN Giordano
Department of Internal Medicine, Endocrine and Metabolic Sciences and Biochemistry, University of Siena, Siena University Hospital Santa Maria alle Scotte, Viale Bracci, Siena, Italy
Scand J Rheumatol 41:391-5. 2012..The aim of this study was to define the pattern of expression of LGR7 in different types of human skin cells and to compare normal skin with lesional and unaffected skin from patients with limited SSc (lSSc)...
Cytokine modulation by endothelin-1 and possible therapeutic implications in systemic sclerosisN Giordano
Department of Internal Medicine, Endocrine Metabolic Sciences and Biochemistry, University of Siena, Siena, Italy
J Biol Regul Homeost Agents 25:487-92. 2011..The aim of this review is to clarify the ET-1 role in SSc, in particular the relationship between ET-1 and cytokine expression, adding another element to the understanding of scleroderma disease...
Bosentan treatment for Raynauds phenomenon and skin fibrosis in patients with Systemic Sclerosis and pulmonary arterial hypertension: an open-label, observational, retrospective studyN Giordano
Department of Internal Medicine, Endocrine Metabolic Sciences and Biochemistry, University of Siena, Italy
Int J Immunopathol Pharmacol 23:1185-94. 2010..01) in the whole cohort. The present data suggest that Bosentan is effective in stabilizing the microcirculation involvement and in improving skin fibrosis irrespective of scleroderma patterns...
Immune and autoimmune disorders in HCV chronic liver disease: personal experience and commentary on literatureNicola Giordano
Department of Internal Medicine, Endocrine Metabolic Sciences and Biochemistry, University of Siena, Italy
New Microbiol 28:311-7. 2005..5%), autoimmune anemia (0.3%) and oral lichen planus (0.3%). We claim that HCV liver infection is able to induce immune and autoimmune perturbations, without playing a significant role in the pathogenesis of a well-defined disorder...
Serum relaxin in systemic sclerosisNicola Giordano
Department of Internal Medicine, Endocrine Metabolic Sciences and Biochemistry, University of Siena, Siena, Italy
J Rheumatol 32:2164-6. 2005..To evaluate serum levels of relaxin (RLX), a hormone with acknowledged antifibrotic activity, in patients with systemic sclerosis (SSc)...
Possible pathogenetic role of antiphospholipid antibodies in a clinical case of human immunodeficiency virus infection with peripheral polyneuropathy and arterial thrombosisNicola Giordano
Department of Internal Medicine, Endocrine Metabolic Sciences and Biochemistry, University of Siena, Italy
New Microbiol 28:261-3. 2005..We suggest that the evaluation of serum antiphospholipid antibodies levels in HIV infection is fundamental both from an exploratory point of view and for starting the best treatment...
Acute hepatitis induced by cyproterone acetateN Giordano
Institute of Internal Medicine, University of Siena, Italy
Ann Pharmacother 35:1053-5. 2001..To report a case of acute hepatitis resulting from the use of cyproterone acetate, an adjuvant treatment for prostate cancer...
IgG and IgM antiganglioside M1 antibodies in primary Sjogren's syndrome with and without peripheral neuropathyN Giordano
Department of Internal Medicine, University of Siena, Viale Bracci 1, 53100 Siena, Italy
Clin Rheumatol 22:256-8. 2003
Hyperuricemia and gout in thyroid endocrine disordersN Giordano
Institute of Internal Medicine, University of Siena, Italy
Clin Exp Rheumatol 19:661-5. 2001..The present study evaluates the prevalence of hyperuricemia and gout in patients affected by primary hypothyroidism and hyperthyroidism...
Serum proteome of patients with systemic sclerosis: molecular analysis of expression and prevalence of haptoglobin alpha chain isoformsR Guerranti
Department of Internal Medicine, Endocrine and Metabolic Sciences and Biochemistry, Faculty of Medicine, University of Siena, Siena, Italy
Int J Immunopathol Pharmacol 23:901-9. 2010..According to our results, the c and e spots can be considered markers for SSc and thus be of use for the early diagnosis of connective tissue disorders and in establishing appropriate treatment...
Efficacy and safety of a musically modulated electromagnetic field (TAMMEF) in patients affected by knee osteoarthritisE Battisti
Department of Medical Physics, University of Siena, Italy
Clin Exp Rheumatol 22:568-72. 2004..In our study we want to value the effects of the TAMMEF (Therapeutic Application of a Musically Modulated Electromagnetic Field) system, which field is piloted by a musical signal...
Comparison between the analgesic and therapeutic effects of a musically modulated electromagnetic field (TAMMEF) and those of a 100 Hz electromagnetic field: blind experiment on patients suffering from cervical spondylosis or shoulder periarthritisM Rigato
Department of Physics, Section of Medical Physics University of Sienna, Italy
J Med Eng Technol 26:253-8. 2002..One group was exposed to the new TAMMEF, another group to the usual ELF, and the third group to simulated treatment. The results show that the effects of the new TAMMEF therapy are equivalent to those obtained with the ELF...
Prevalence of Paget's disease of bone in ItalyLuigi Gennari
Department of Internal Medicine, Endocrine Metabolic Sciences and Biochemistry, University of Siena, Siena, and Department of Radiology, U O A I S Giovanni Battista Hospital of Torino, Italy
J Bone Miner Res 20:1845-50. 2005..7% to 2.4%, were higher in males than in females, and slightly differed between the two towns. Unlike previous studies in populations of British descent, no secular trend for a decreasing prevalence emerged...
Alterations in adenylate kinase activity in human PBMCs after in vitro exposure to electromagnetic field: comparison between extremely low frequency electromagnetic field (ELF) and therapeutic application of a musically modulated electromagnetic field (TAAntonietta Albanese
TAMMEF Centre, University of Siena, Siena 53100, Italy
J Biomed Biotechnol 2009:717941. 2009..In contrast, TAMMEF fields may be useful for maintaining and regulating the cellular electrical charge...
In vitro exposure of human osteoarthritic chondrocytes to ELF fields and new therapeutic application of musically modulated electromagnetic fields: biological evidenceD Vannoni
Department of Internal Medicine, Endocrine Metabolic Sciences and Biochemistry, University of Siena, Italy
J Biol Regul Homeost Agents 26:39-49. 2012..We can conclude that both ELF and TAMMEF systems could be recommended for OA therapy and represent a valid non-pharmacological approach to the treatment of this pathology...
Magnetic resonance imaging in Tietze's syndromeL Volterrani
Department of Human Pathology and Oncology, Department of Clinical and Immunological Science, University of Siena, Siena, Italy
Clin Exp Rheumatol 26:848-53. 2008..To evaluate the usefulness of magnetic resonance imaging (MRI) in Tietze's syndrome which, to our knowledge, has not previously been reported in the literature...
H pylori infection and systemic antibodies to CagA and heat shock protein 60 in patients with coronary heart diseaseCristina Lenzi
Department of Internal Medicine Endocrine-Metabolic Sciences and Biochemistry, University of Siena, Siena, Italy
World J Gastroenterol 12:7815-20. 2006..007). CONCLUSION: CagA positive H pylori infection may concur to the development of CHD; high levels of anti-Hsp60 antibodies may constitute a marker and/or a concomitant pathogenic factor of the disease...
HLA antigens and primary osteoarthritis of the handDaniela Merlotti
Department of Internal Medicine, University of Siena, Italy
J Rheumatol 30:1298-304. 2003..Haplotype analysis showed an association of B35-DQ1, B40-DQ1, and DR2-DQ1 with increased OA risk. CONCLUSION: Our results suggest a role of the HLA system in the etiopathogenesis of primary OA of the hand...
Is polymyalgia rheumatica caused by infectious agents?Ranuccio Nuti
J Rheumatol 32:200-1. 2005
