Giuseppe Gerna

Summary

Affiliation: University of Pavia
Country: Italy

Publications

  1. pmc Enterovirus genotype EV-104 in humans, Italy, 2008-2009
    Antonio Piralla
    Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico Policlinico, San Matteo, Pavia, Italy
    Emerg Infect Dis 16:1018-21. 2010
  2. pmc Monitoring of human cytomegalovirus and virus-specific T-cell response in young patients receiving allogeneic hematopoietic stem cell transplantation
    Daniele Lilleri
    Laboratori Sperimentali di Ricerca, Area Trapiantologica, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    PLoS ONE 7:e41648. 2012
  3. pmc Fetal human cytomegalovirus transmission correlates with delayed maternal antibodies to gH/gL/pUL128-130-131 complex during primary infection
    Daniele Lilleri
    Laboratori Sperimentali di Ricerca, Area Trapiantologica, Fondazione Istituto Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy
    PLoS ONE 8:e59863. 2013
  4. doi request reprint Maternal, fetal and neonatal diagnosis of congenital human cytomegalovirus infection
    Maria Grazia Revello
    Servizio di Virologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy 39 0382502644 39 0382502599
    Expert Opin Med Diagn 2:547-63. 2008
  5. ncbi request reprint Human cytomegalovirus end-organ disease is associated with high or low systemic viral load in preemptively treated solid-organ transplant recipients
    Giuseppe Gerna
    Laboratori Sperimentali di Ricerca, Area Trapiantologica, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    New Microbiol 35:279-87. 2012
  6. ncbi request reprint Endothelial cells and CMV dissemination
    Giuseppe Gerna
    Laboratori Sperimentali di Ricerca, Area Trapiantologica, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy
    Future Microbiol 7:441-4. 2012
  7. doi request reprint Prophylaxis followed by preemptive therapy versus preemptive therapy for prevention of human cytomegalovirus disease in pediatric patients undergoing liver transplantation
    Giuseppe Gerna
    Servizio di Virologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    Transplantation 86:163-6. 2008
  8. ncbi request reprint In vitro model for the study of the dissociation of increasing antigenemia and decreasing DNAemia and viremia during treatment of human cytomegalovirus infection with ganciclovir in transplant recipients
    Giuseppe Gerna
    Servizio di Virologia, Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy
    J Infect Dis 188:1639-47. 2003
  9. ncbi request reprint Monitoring of human cytomegalovirus-specific CD4 and CD8 T-cell immunity in patients receiving solid organ transplantation
    G Gerna
    Servizio di Virologia, Universita di Pavia, Pavia, Italy
    Am J Transplant 6:2356-64. 2006
  10. ncbi request reprint Human cytomegalovirus pp67 mRNAemia versus pp65 antigenemia for guiding preemptive therapy in heart and lung transplant recipients: a prospective, randomized, controlled, open-label trial
    Giuseppe Gerna
    Servizio di Virologia, IRCCS Policlinico San Matteo, 27100 Pavia, Italy
    Transplantation 75:1012-9. 2003

Detail Information

Publications114 found, 100 shown here

  1. pmc Enterovirus genotype EV-104 in humans, Italy, 2008-2009
    Antonio Piralla
    Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico Policlinico, San Matteo, Pavia, Italy
    Emerg Infect Dis 16:1018-21. 2010
    ..EV-104 is closely related to human rhinoviruses; thus, both types of viruses should be sought in respiratory syndromes...
  2. pmc Monitoring of human cytomegalovirus and virus-specific T-cell response in young patients receiving allogeneic hematopoietic stem cell transplantation
    Daniele Lilleri
    Laboratori Sperimentali di Ricerca, Area Trapiantologica, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    PLoS ONE 7:e41648. 2012
    ..The decision to treat HCMV infection in young HSCT recipients may be taken by combining virological and immunological findings...
  3. pmc Fetal human cytomegalovirus transmission correlates with delayed maternal antibodies to gH/gL/pUL128-130-131 complex during primary infection
    Daniele Lilleri
    Laboratori Sperimentali di Ricerca, Area Trapiantologica, Fondazione Istituto Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy
    PLoS ONE 8:e59863. 2013
    ..Taken together, these findings indicate that the HCMV pentamer complex is a major target of the antibody-mediated maternal immunity...
  4. doi request reprint Maternal, fetal and neonatal diagnosis of congenital human cytomegalovirus infection
    Maria Grazia Revello
    Servizio di Virologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy 39 0382502644 39 0382502599
    Expert Opin Med Diagn 2:547-63. 2008
    ..Conclusions: Without an HCMV vaccine, diagnosis of primary infection in the mother and of congenital infection in the fetus/newborn are key factors for management of congenital HCMV infection...
  5. ncbi request reprint Human cytomegalovirus end-organ disease is associated with high or low systemic viral load in preemptively treated solid-organ transplant recipients
    Giuseppe Gerna
    Laboratori Sperimentali di Ricerca, Area Trapiantologica, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    New Microbiol 35:279-87. 2012
    ....
  6. ncbi request reprint Endothelial cells and CMV dissemination
    Giuseppe Gerna
    Laboratori Sperimentali di Ricerca, Area Trapiantologica, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy
    Future Microbiol 7:441-4. 2012
    ....
  7. doi request reprint Prophylaxis followed by preemptive therapy versus preemptive therapy for prevention of human cytomegalovirus disease in pediatric patients undergoing liver transplantation
    Giuseppe Gerna
    Servizio di Virologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    Transplantation 86:163-6. 2008
    ..Therefore, the trial was interrupted and prophylaxis replaced with preemptive therapy alone. In parallel, the development of T-cell-mediated immune response was found to be comparable in both arms...
  8. ncbi request reprint In vitro model for the study of the dissociation of increasing antigenemia and decreasing DNAemia and viremia during treatment of human cytomegalovirus infection with ganciclovir in transplant recipients
    Giuseppe Gerna
    Servizio di Virologia, Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy
    J Infect Dis 188:1639-47. 2003
    ..The conclusion for clinicians is that antiviral therapy must be changed only in the latter case...
  9. ncbi request reprint Monitoring of human cytomegalovirus-specific CD4 and CD8 T-cell immunity in patients receiving solid organ transplantation
    G Gerna
    Servizio di Virologia, Universita di Pavia, Pavia, Italy
    Am J Transplant 6:2356-64. 2006
    ..5%) were affected by HCMV infections requiring antiviral treatment (p = <0.0001). Simultaneous monitoring of HCMV infection and HCMV-specific T-cell immunity predicts T-cell-mediated control of HCMV infection...
  10. ncbi request reprint Human cytomegalovirus pp67 mRNAemia versus pp65 antigenemia for guiding preemptive therapy in heart and lung transplant recipients: a prospective, randomized, controlled, open-label trial
    Giuseppe Gerna
    Servizio di Virologia, IRCCS Policlinico San Matteo, 27100 Pavia, Italy
    Transplantation 75:1012-9. 2003
    ..However, standardized protocols are not available. In particular, whether a qualitative molecular assay for detection of a late (pp67) HCMV mRNA represents a valuable alternative to quantitative antigenemia remains to be defined...
  11. ncbi request reprint Evaluation of cytomegalovirus DNAaemia versus pp65-antigenaemia cutoff for guiding preemptive therapy in transplant recipients: a randomized study
    Giuseppe Gerna
    Servizio di Virologia, Fondazione, IRCCS Policlinico San Matteo, Pavia, Italy
    Antivir Ther 12:63-72. 2007
    ..Antiviral treatment was started in both seropositive and seronegative patients when levels greater than 300,000 DNA copies/ml blood or 100 pp65-positive leukocytes in the relevant arm were reached...
  12. ncbi request reprint Rescue of human cytomegalovirus strain AD169 tropism for both leukocytes and human endothelial cells
    Giuseppe Gerna
    Servizio di Virologia, IRCCS Policlinico San Matteo, 27100 Pavia, Italy
    J Gen Virol 84:1431-6. 2003
    ..The lack of a 15 kb DNA fragment in the strain AD169 genome does not prevent the rescue of these biological functions, thus indicating that they are likely to be encoded by viral genes located elsewhere...
  13. ncbi request reprint Monitoring transplant patients for human cytomegalovirus: Diagnostic update
    Giuseppe Gerna
    Virology Service, IRCCS Policlinico San Matteo, Pavia, Italy
    Herpes 13:4-11. 2006
    ....
  14. doi request reprint Human cytomegalovirus serum neutralizing antibodies block virus infection of endothelial/epithelial cells, but not fibroblasts, early during primary infection
    Giuseppe Gerna
    Servizio di Virologia, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy
    J Gen Virol 89:853-65. 2008
    ..Hence, conventional determination of the neutralizing activity of human sera in fibroblasts is misleading. Antibodies to pUL131A, pUL130 and pUL128 appear to display a major HCMV-neutralizing and dissemination-inhibiting activity...
  15. ncbi request reprint Pathogenesis of human cytomegalovirus infection and cellular targets
    Giuseppe Gerna
    Servizio di Virologia, IRCCS Policlinico San Matteo, Pavia, Italy
    Hum Immunol 65:381-6. 2004
    ..The interaction of endothelial cells and leukocytes with subsequent spreading of infection to smooth muscle cells may be a major pathogenetic mechanism at the basis of this important vascular disease...
  16. ncbi request reprint Genetic variability of human coronavirus OC43-, 229E-, and NL63-like strains and their association with lower respiratory tract infections of hospitalized infants and immunocompromised patients
    Giuseppe Gerna
    Servizio di Virologia, IRCCS Policlinico San Matteo, and Dipartimento di Pediatria, Universita di Pavia, Pavia, Italy
    J Med Virol 78:938-49. 2006
    ..Finally, hCoVs should be screened routinely for in both infants and immunocompromised patients with acute respiratory infection...
  17. doi request reprint Validation of a DNAemia cutoff for preemptive therapy of cytomegalovirus infection in adult hematopoietic stem cell transplant recipients
    G Gerna
    Servizio di Virologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    Bone Marrow Transplant 41:873-9. 2008
    ..In conclusion, our study shows that the use of a cutoff significantly reduces the number of patients requiring antiviral treatment, thus sparing unnecessary drug administration...
  18. ncbi request reprint Dendritic-cell infection by human cytomegalovirus is restricted to strains carrying functional UL131-128 genes and mediates efficient viral antigen presentation to CD8+ T cells
    Giuseppe Gerna
    Servizio di Virologia, IRCCS Policlinico San Matteo, 27100 Pavia, Italy
    J Gen Virol 86:275-84. 2005
    ..DC incubated with inactivated crude whole viral antigen preparations were only capable of eliciting a significant CD4+-mediated immune response...
  19. ncbi request reprint Impact of human metapneumovirus and human cytomegalovirus versus other respiratory viruses on the lower respiratory tract infections of lung transplant recipients
    Giuseppe Gerna
    Servizio di Virologia, IRCCS Policlinico San Matteo, Universita di Pavia, Pavia, Italy
    J Med Virol 78:408-16. 2006
    ....
  20. ncbi request reprint Correlation of viral load as determined by real-time RT-PCR and clinical characteristics of respiratory syncytial virus lower respiratory tract infections in early infancy
    G Gerna
    Servizio di Virologia, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy
    J Clin Virol 41:45-8. 2008
    ..In infants hospitalized for a lower respiratory tract infection (RTI) caused by respiratory syncytial virus (RSV), the correlation between viral load (VL) and patient clinical characteristics remains to be defined...
  21. ncbi request reprint The human bocavirus role in acute respiratory tract infections of pediatric patients as defined by viral load quantification
    Giuseppe Gerna
    Servizio di Virologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    New Microbiol 30:383-92. 2007
    ..Below this cut-off, hBoV appeared to be an innocent bystander or a persistent virus. Although hBoV may be frequently detected in children with upper or lower ARTI, in less than 50% young patients it appears to be potentially pathogenic...
  22. ncbi request reprint Prospective study of human metapneumovirus infection: diagnosis, typing and virus quantification in nasopharyngeal secretions from pediatric patients
    Giuseppe Gerna
    Servizio di Virologia, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy
    J Clin Virol 40:236-40. 2007
    ..During the winter-spring seasons 2004-2005 and 2005-2006, 965 nasopharyngeal aspirates from 871 patients were examined for human metapneumovirus (hMPV) by both monoclonal antibodies (MAbs) and reverse transcription (RT)-PCR...
  23. doi request reprint Preemptive therapy for systemic and pulmonary human cytomegalovirus infection in lung transplant recipients
    G Gerna
    Servizio di Virologia, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy
    Am J Transplant 9:1142-50. 2009
    ..In addition, monitoring the HCMV-specific T-cell immune response appears useful for predicting control of HCMV infection in the posttransplant period...
  24. ncbi request reprint The attenuated Towne strain of human cytomegalovirus may revert to both endothelial cell tropism and leuko- (neutrophil- and monocyte-) tropism in vitro
    Giuseppe Gerna
    Servizio di Virologia, IRCCS Policlinico San Matteo, 27100 Pavia, Italy
    J Gen Virol 83:1993-2000. 2002
    ..Viral genes involved in endothelial cell tropism and leukotropism remain to be identified. However, reversion of attenuated strains to pathogenicity in vivo cannot be excluded a priori...
  25. ncbi request reprint Management of human cytomegalovirus infection in transplantation: validation of virologic cut-offs for preemptive therapy and immunological cut-offs for protection
    Giuseppe Gerna
    Laboratori Sperimentali di Ricerca, Area Trapiantologica, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    New Microbiol 34:229-54. 2011
    ..However, anti-rejection in SOTR and anti- GvHD in HSCTR steroid therapies make patients susceptible to HCMV infection, even in the presence of protective levels of specific T-cells...
  26. pmc Human cytomegalovirus replicates abortively in polymorphonuclear leukocytes after transfer from infected endothelial cells via transient microfusion events
    G Gerna
    Servizio di Virologia, Area Infettivologica, Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, 27100 Pavia, Italy
    J Virol 74:5629-38. 2000
    ....
  27. pmc Human cytomegalovirus immediate-early mRNA detection by nucleic acid sequence-based amplification as a new parameter for preemptive therapy in bone marrow transplant recipients
    G Gerna
    Servizio di Virologia, Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Universita di Pavia, 27100 Pavia, Italy
    J Clin Microbiol 38:1845-53. 2000
    ..HCMV IE mRNA detection may represent a useful parameter for initiation of preemptive therapy in BMT recipients...
  28. ncbi request reprint Human cytomegalovirus immediate-early mRNAemia versus pp65 antigenemia for guiding pre-emptive therapy in children and young adults undergoing hematopoietic stem cell transplantation: a prospective, randomized, open-label trial
    Giuseppe Gerna
    Servizio di Virologia, Division di Oncoematologia Pediatrica, Istituto di Ricovero e Cura a Carattee Scientifico Policlinico San Matteo, Pavia, Italy
    Blood 101:5053-60. 2003
    ..Although these data indicate that IEmRNA determination does not offer advantages in terms of treatment duration, it can safely replace antigenemia, while semiautomation is the major advantage of the NASBA procedure...
  29. ncbi request reprint Human respiratory coronavirus HKU1 versus other coronavirus infections in Italian hospitalised patients
    Giuseppe Gerna
    Servizio di Virologia, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy
    J Clin Virol 38:244-50. 2007
    ..Human respiratory coronavirus (hCoV) HKU1 infections were reported for the first time in 2005 in Hong Kong...
  30. ncbi request reprint Declining levels of rescued lymphoproliferative response to human cytomegalovirus (HCMV) in AIDS patients with or without HCMV disease following long-term HAART
    G Gerna
    Servizio di Virologia, IRCCS Policlinico San Matteo, Pavia, Italy
    J Acquir Immune Defic Syndr 28:320-31. 2001
    ..All patients had previously undergone antiretroviral monotherapy or dual therapy before initiating HAART...
  31. pmc Human cytomegalovirus and human umbilical vein endothelial cells: restriction of primary isolation to blood samples and susceptibilities of clinical isolates from other sources to adaptation
    Giuseppe Gerna
    Servizio di Virologia, IRCCS Policlinico San Matteo, 27100 Pavia, Italy
    J Clin Microbiol 40:233-8. 2002
    ....
  32. ncbi request reprint Lack of transmission to polymorphonuclear leukocytes and human umbilical vein endothelial cells as a marker of attenuation of human cytomegalovirus
    Giuseppe Gerna
    Servizio di Virologia, IRCCS Policlinico San Matteo, Pavia, Italy
    J Med Virol 66:335-9. 2002
    ....
  33. ncbi request reprint Correlation of rhinovirus load in the respiratory tract and clinical symptoms in hospitalized immunocompetent and immunocompromised patients
    G Gerna
    Servizio di Virologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    J Med Virol 81:1498-507. 2009
    ....
  34. doi request reprint Virologic and immunologic monitoring of cytomegalovirus to guide preemptive therapy in solid-organ transplantation
    G Gerna
    Laboratori Sperimentali di Ricerca, Area Trapiantologica, Fondazione IRCCS Policlinico San Matteo, Pavia 27100, Italy
    Am J Transplant 11:2463-71. 2011
    ..4/μL blood appears to be protective against HCMV disease. This result does not apply to patients undergoing antirejection treatment, or reconstituting HCMV-specific CD8+ T cells only...
  35. ncbi request reprint Surveillance of influenza virus B circulation in Northern Italy: summer-fall 2008 isolation of three strains and phylogenetic analysis
    Giuseppe Gerna
    Servizio di Virologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    New Microbiol 32:405-10. 2009
    ..Surveillance of influenza virus circulation in Western countries also during the summer-fall season may help to trace and anticipate the appearance of new influenza virus variants...
  36. ncbi request reprint Monoclonal antibodies versus reverse transcription-PCR for detection of respiratory viruses in a patient population with respiratory tract infections admitted to hospital
    Francesca Rovida
    Servizio di Virologia, IRCCS Policlinico San Matteo, Pavia, Italy
    J Med Virol 75:336-47. 2005
    ....
  37. ncbi request reprint Detection and pathogenicity of human metapneumovirus respiratory infection in pediatric Italian patients during a winter--spring season
    Antonella Sarasini
    Servizio di Virologia IRCCS Policlinico San Matteo and University of Pavia, Via Taramelli 5, 27100 Pavia, Italy
    J Clin Virol 35:59-68. 2006
    ..Some diagnostic, epidemiological and clinical features of the recently discovered human metapneumovirus remain to be investigated...
  38. doi request reprint Human cytomegalovirus-specific CD4+ and CD8+ T-cell reconstitution in adult allogeneic hematopoietic stem cell transplant recipients and immune control of viral infection
    Daniele Lilleri
    Servizio di Virologia, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy
    Haematologica 93:248-56. 2008
    ..We investigated the development of human cytomegalovirus-specific T cells in adult recipients of hematopoietic stem cell transplants...
  39. doi request reprint Human cytomegalovirus-specific CD4(+) and CD8(+) T-cell response determination: comparison of short-term (24h) assays vs long-term (7-day) infected dendritic cell assay in the immunocompetent and the immunocompromised host
    Paola Zelini
    Service of Virology and Microbiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    Clin Immunol 136:269-81. 2010
    ..A significant correlation between iDC-activated T-cells and T-cells activated by either iCL or the pep-pool was observed. In conclusion, whenever a rapid result is needed, short-term assays may efficiently replace the iDC assay...
  40. ncbi request reprint Monitoring of human cytomegalovirus (HCMV)-specific CD4+ T cell frequency by cytokine flow cytometry as a possible indicator for discontinuation of HCMV secondary prophylaxis in HAART-treated AIDS patients
    Daniele Lilleri
    Servizio di Virologia, IRCCS Policlinico San Matteo, Via Taramelli 5, 27100 Pavia, Italy
    J Clin Virol 29:297-307. 2004
    ....
  41. doi request reprint Human cytomegalovirus-specific CD4+ and CD8+ T cell responses in primary infection of the immunocompetent and the immunocompromised host
    Daniele Lilleri
    Servizio di Virologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    Clin Immunol 131:395-403. 2009
    ..Thus, the development of cell-mediated immune response in primary HCMV infection may be missed when looking at pp65 and IE-1 peptide-stimulated T-cells only...
  42. ncbi request reprint Human cytomegalovirus double resistance in a donor-positive/recipient-negative lung transplant patient with an impaired CD4-mediated specific immune response
    Fausto Baldanti
    Servizio di Virologia and Laboratori Sperimentali di Ricerca, IRCCS Policlinico San Matteo, 27100 Pavia, Italy
    J Antimicrob Chemother 53:536-9. 2004
    ..Emergence of human cytomegalovirus (HCMV) resistance to ganciclovir in solid-organ transplant recipients has been found to be mostly associated with primary HCMV infection...
  43. pmc Gln145Met/Leu changes in human immunodeficiency virus type 1 reverse transcriptase confer resistance to nucleoside and nonnucleoside analogs and impair virus replication
    Stefania Paolucci
    Servizio di Virologia, IRCCS Policlinico San Matteo, Pavia, Italy
    Antimicrob Agents Chemother 48:4611-7. 2004
    ..This finding may explain the lower frequency of Gln145Met/Leu mutations observed compared with the frequencies of Gln151Met/Leu mutations and the insertion at position 69 in HAART-experienced patients...
  44. ncbi request reprint Lymphoproliferative response in primary human cytomegalovirus (HCMV) infection is delayed in HCMV transmitter mothers
    Maria Grazia Revello
    Servizio di Virologia, Istituto di Ricovero e Cura a Carattere Scientifico, Policlinico San Matteo, Pavia, Italy
    J Infect Dis 193:269-76. 2006
    ..The T cell-mediated immune response to human cytomegalovirus (HCMV) after primary infection, as well as the determinants of intrauterine transmission, are poorly understood...
  45. ncbi request reprint Clinically-based determination of safe DNAemia cutoff levels for preemptive therapy or human cytomegalovirus infections in solid organ and hematopoietic stem cell transplant recipients
    Daniele Lilleri
    Servizio di Virologia, IRCCS Policlinico San Matteo, Pavia, Italy
    J Med Virol 73:412-8. 2004
    ..Retrospective DNAemia cutoff values will be verified for safety in prospective trials...
  46. doi request reprint Serum antibody response to the gH/gL/pUL128-131 five-protein complex of human cytomegalovirus (HCMV) in primary and reactivated HCMV infections
    Emilia Genini
    SC Virologia e Microbiologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    J Clin Virol 52:113-8. 2011
    ..Recently, a new human cytomegalovirus (HCMV) glycoprotein complex has been identified and potentially proposed as a vaccine...
  47. ncbi request reprint Prospective simultaneous quantification of human cytomegalovirus-specific CD4+ and CD8+ T-cell reconstitution in young recipients of allogeneic hematopoietic stem cell transplants
    Daniele Lilleri
    Servizio di Virologia, Instituto di Ricovero e Cura a Carattere Scientifico San Matteo, 27100 Pavia, Italy
    Blood 108:1406-12. 2006
    ....
  48. ncbi request reprint Simultaneous quantification of human cytomegalovirus (HCMV)-specific CD4+ and CD8+ T cells by a novel method using monocyte-derived HCMV-infected immature dendritic cells
    Laura Lozza
    Servizio di Virologia, IRCCS Policlinico San Matteo, Pavia, Italy
    Eur J Immunol 35:1795-804. 2005
    ..The novel ex vivo assay enables the simultaneous evaluation of HCMV-specific CD4(+) and CD8(+) T cell responses and may be a useful tool for monitoring HCMV-specific T cell activity in immunocompromised transplanted patients...
  49. ncbi request reprint NNRTI-selected mutations at codon 190 of human immunodeficiency virus type 1 reverse transcriptase decrease susceptibility to stavudine and zidovudine
    Stefania Paolucci
    Servizio di Virologia, IRCCS Policlinico San Matteo, 27100 Pavia, Italy
    Antiviral Res 76:99-103. 2007
    ..Selection of double mutants, with further decrease in NRTI susceptibility, might be favoured by the compensatory effect of T215Y on the reduction of RT catalytic efficiency associated with G190S...
  50. doi request reprint Antibodies against neutralization epitopes of human cytomegalovirus gH/gL/pUL128-130-131 complex and virus spreading may correlate with virus control in vivo
    Daniele Lilleri
    Laboratori Sperimentali di Ricerca, Area Trapiantologica, Fondazione IRCCS Policlinico San Matteo, 27100, Pavia, Italy
    J Clin Immunol 32:1324-31. 2012
    ..Purpose of this study was to verify whether in vitro activities of these antibodies may correlate with protection in vivo...
  51. doi request reprint Human rhinovirus and human respiratory enterovirus (EV68 and EV104) infections in hospitalized patients in Italy, 2008-2009
    Antonio Piralla
    S S Virologia Molecolare, S C Virologia e Microbiologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    Diagn Microbiol Infect Dis 73:162-7. 2012
    ..001). HRVs are often the cause of LRTI in children less than 5 years, frequently in association with a high viral load...
  52. doi request reprint Human cytomegalovirus-specific T cell reconstitution in young patients receiving T cell-depleted, allogeneic hematopoietic stem cell transplantation
    Daniele Lilleri
    Servizio di Virologia, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Universita di Pavia, Pavia, Italy
    J Infect Dis 199:829-36. 2009
    ..Scarce data on this subject are available for children receiving a T cell-depleted HSCT...
  53. ncbi request reprint Rapid typing, subtyping and RNA quantification of influenza virus type A strains in respiratory secretions
    Elena Percivalle
    Servizio di Virologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    New Microbiol 31:319-27. 2008
    ..In conclusion, typing and subtyping of influenza virus type A strains may benefit from both MAbs and RT-PCR, while viral RNA quantification may provide an indication of symptom onset...
  54. ncbi request reprint Human respiratory syncytial virus (hRSV) RNA quantification in nasopharyngeal secretions identifies the hRSV etiologic role in acute respiratory tract infections of hospitalized infants
    Giulia Campanini
    Servizio di Virologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    J Clin Virol 39:119-24. 2007
    ..HRSV RNA quantification may help in affording this issue...
  55. ncbi request reprint Novel recombinant phenotypic assay for clonal analysis of reverse transcriptase mutations conferring drug resistance to HIV-1 variants
    Stefania Paolucci
    Servizio di Virologia and Laboratori Sperimentali di Ricerca, IRCCS Policlinico San Matteo, 27100 Pavia, Italy
    J Antimicrob Chemother 53:766-71. 2004
    ..A novel rapid reverse transcriptase (RT) recombinant HIV-1 drug-susceptibility assay was developed to evaluate resistance to RT inhibitors...
  56. ncbi request reprint Development of human cytomegalovirus-specific T cell immunity during primary infection of pregnant women and its correlation with virus transmission to the fetus
    Daniele Lilleri
    Servizio di Virologia, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico, Policlinico San Matteo, Pavia, Italy
    J Infect Dis 195:1062-70. 2007
    ..We sought to study the development of human cytomegalovirus (HCMV)-specific T cell-mediated immune responses during primary HCMV infection in pregnancy...
  57. ncbi request reprint Multiple relapses of human cytomegalovirus retinitis during HAART in an AIDS patient with reconstitution of CD4+ T cell count in the absence of HCMV-specific CD4+ T cell response
    Daniele Lilleri
    Servizio di Virologia, IRCCS Policlinico S Matteo, 27100 Pavia, Italy
    J Clin Virol 26:95-100. 2003
    ..However, cases of HCMV disease in HIV-infected patients treated with HAART have been reported...
  58. ncbi request reprint Molecular epidemiology of primary human cytomegalovirus infection in pregnant women and their families
    Maria Grazia Revello
    Servizio di Virologia, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy
    J Med Virol 80:1415-25. 2008
    ..A child rather than the husband was the virus source for the great majority of pregnant women. No association was observed between UL144 polymorphisms and intrauterine transmission...
  59. doi request reprint Human parechovirus infections in patients admitted to hospital in Northern Italy, 2008-2010
    Antonio Piralla
    Virology and Microbiology Department, Molecular Virology Unit, Foundation IRCCS Policlinico San Matteo, Pavia, Italy
    J Med Virol 84:686-90. 2012
    ..Although not circulating at high frequency and unlikely to cause respiratory syndrome, HPeV was associated with severe clinical syndromes in a minority of newborns...
  60. ncbi request reprint Rising antigenemia levels may be misleading in pre-emptive therapy of human cytomegalovirus infection in allogeneic hematopoietic stem cell transplant recipients
    Giuseppe Gerna
    Servizio di Virologia, Oncoematologia Pediatrica, and Centro Trapianti di Midollo Osseo, Divisione di Ematologia, IRCCS Policlinico San Matteo, 27100 Pavia, Italy
    Haematologica 90:526-33. 2005
    ..This raises some doubts about the therapeutic decisions to be taken...
  61. doi request reprint Comparative evaluation of eight commercial human cytomegalovirus IgG avidity assays
    Maria Grazia Revello
    SC Ostetricia e Ginecologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    J Clin Virol 48:255-9. 2010
    ..Determination of HCMV-specific IgG avidity is considered an useful approach for distinguishing IgM antibody due to primary HCMV infection from IgM antibody elicited during non-primary infection...
  62. pmc Multicluster nosocomial outbreak of parainfluenza virus type 3 infection in a pediatric oncohematology unit: a phylogenetic study
    Antonio Piralla
    Servizio di Virologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    Haematologica 94:833-9. 2009
    ..Human parainfluenza virus type 3 (hPIV-3) has been reported to cause nosocomial outbreaks of respiratory infection, in particular among hematopoietic stem cell transplantation recipients...
  63. ncbi request reprint Clinical and biologic aspects of human cytomegalovirus resistance to antiviral drugs
    Fausto Baldanti
    Servizio di Virologia, IRCCS Policlinico San Matteo, Pavia, Italy
    Hum Immunol 65:403-9. 2004
    ....
  64. doi request reprint Human cytomegalovirus load measurement and its applications for pre-emptive therapy in patients undergoing hematopoietic stem cell transplantation
    Fausto Baldanti
    Servizio di Virologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    Hematol Oncol 26:123-30. 2008
    ....
  65. doi request reprint Human cytomegalovirus (HCMV) DNAemia in the mother at amniocentesis as a risk factor for iatrogenic HCMV infection of the fetus
    Maria Grazia Revello
    Servizio di Virologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    J Infect Dis 197:593-6. 2008
    ..Therefore, maternal HCMV DNAemia is not a significant risk factor for iatrogenic HCMV transmission to the fetus during amniocentesis...
  66. pmc Prenatal diagnosis of congenital human cytomegalovirus infection in amniotic fluid by nucleic acid sequence-based amplification assay
    M Grazia Revello
    Servizio di Virologia, Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, 27100 Pavia, Italy
    J Clin Microbiol 41:1772-4. 2003
    ....
  67. ncbi request reprint Preconceptional primary human cytomegalovirus infection and risk of congenital infection
    Maria Grazia Revello
    Servizio di Virologia, Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy
    J Infect Dis 193:783-7. 2006
    ..Although a safe time interval between primary infection and initiation of pregnancy still needs to be defined, documented information can now be provided during counseling...
  68. ncbi request reprint Amino acid insertions at position 35 of HIV-1 protease interfere with virus replication without modifying antiviral drug susceptibility
    Stefania Paolucci
    Servizio di Virologia, IRCCS Policlinico San Matteo, 27100 Pavia, Italy
    Antiviral Res 69:181-5. 2006
    ..Comparison of ins35TN+res.muts and ins35G+res.muts with respect to the corresponding recombinant rescue mutants showed that ins35TN decreased the replication rate of the PI-resistant strain, while ins35G had a protective effect...
  69. doi request reprint Role of prenatal diagnosis and counseling in the management of 735 pregnancies complicated by primary human cytomegalovirus infection: a 20-year experience
    Maria Grazia Revello
    SC Ostetricia e Ginecologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    J Clin Virol 50:303-7. 2011
    ..The burden of congenital human cytomegalovirus (HCMV) infection is well recognized. However, screening for maternal infection remains controversial in view of diagnostic challenges, counseling difficulties, and absence of medical treatment...
  70. pmc Rapid detection of human metapneumovirus strains in nasopharyngeal aspirates and shell vial cultures by monoclonal antibodies
    Elena Percivalle
    Servizio di Virologia, IRCCS Policlinico San Matteo, 27100 Pavia, Italy
    J Clin Microbiol 43:3443-6. 2005
    ..9%, 94.1%, 94.4%, and 72.7%, respectively. Monoclonal antibodies are useful for direct hMPV detection...
  71. ncbi request reprint Genomes of the endothelial cell-tropic variant and the parental Toledo strain of human cytomegalovirus are highly divergent
    Fausto Baldanti
    Servizio di Virologia, IRCCS Policlinico San Matteo, Pavia, Italy
    J Med Virol 69:76-81. 2003
    ..In conclusion, the degree of dissimilarity between the two genomes suggests that the endothelial cell-tropic variant of the Toledo strain could have originated from a recombination event...
  72. ncbi request reprint Use of a DNAemia cut-off for monitoring human cytomegalovirus infection reduces the number of preemptively treated children and young adults receiving hematopoietic stem-cell transplantation compared with qualitative pp65 antigenemia
    Daniele Lilleri
    Servizio di Virologia, Universita di Pavia, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico IRCCS Policlinico San Matteo, Pavia, Italy
    Blood 110:2757-60. 2007
    ..259), the number of patients treated was significantly lower in the DNAemia arm (18% vs 31%, P = .026). No patient developed HCMV disease. The use of a DNAemia cut-off avoids unnecessary antiviral treatment...
  73. ncbi request reprint Nevirapine-selected mutations Y181I/C of HIV-1 reverse transcriptase confer cross-resistance to stavudine
    Fausto Baldanti
    Servizio di Virologia, IRCCS Policlinico San Matteo, Pavia, Italy
    AIDS 17:1568-70. 2003
    ..A previously unnoticed role of Y181I/C RT changes selected by nevirapine or other NNRTI in determining stavudine resistance is documented...
  74. ncbi request reprint In vitro selection of human cytomegalovirus variants unable to transfer virus and virus products from infected cells to polymorphonuclear leukocytes and to grow in endothelial cells
    M Grazia Revello
    Servizio di Virologia, Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, 27100 Pavia, Italy
    J Gen Virol 82:1429-38. 2001
    ..These findings link EC and PMNL tropism and suggest that PMNL tropism is a late HCMV function...
  75. ncbi request reprint Human cytomegalovirus UL131A, UL130 and UL128 genes are highly conserved among field isolates
    F Baldanti
    Servizio di Virologia, IRCCS Policlinico San Matteo, Pavia, Italy
    Arch Virol 151:1225-33. 2006
    ..The conservation of the UL131A-UL128 locus is consistent with the conclusion that the three encoded proteins are all essential for growth of HCMV in endothelial cells and virus transfer to leukocytes...
  76. doi request reprint Monitoring human cytomegalovirus infection in transplant recipients
    Fausto Baldanti
    Servizio di Virologia, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy
    J Clin Virol 41:237-41. 2008
    ..To understand the mechanism behind long-term control of HCMV infection in transplant recipients, the HCMV-specific T-cell response must be evaluated...
  77. ncbi request reprint Higher levels of HIV DNA in memory and naive CD4(+) T cell subsets of viremic compared to non-viremic patients after 18 and 24 months of HAART
    F Baldanti
    Servizio di Virologia, Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Via Taramelli 5, 27100 Pavia, Italy
    Antiviral Res 50:197-206. 2001
    ..Immunological reconstitution following HAART might potentially be hampered in viremic patients despite the absolute increase in CD4(+) T cell counts...
  78. ncbi request reprint Prenatal diagnostic and prognostic value of human cytomegalovirus load and IgM antibody response in blood of congenitally infected fetuses
    M Grazia Revello
    Servizio di Virologia, IRCCS Policlinico San Matteo, 27100 Pavia, Italy
    J Infect Dis 180:1320-3. 1999
    ..Taken together, virologic, laboratory, and ultrasound findings may contribute to a better prognostic definition of fetal HCMV infection...
  79. pmc Diagnosis and management of human cytomegalovirus infection in the mother, fetus, and newborn infant
    Maria Grazia Revello
    Servizio di Virologia, IRCCS Policlinico San Matteo, 27100 Pavia, Italy
    Clin Microbiol Rev 15:680-715. 2002
    ....
  80. ncbi request reprint Comparison of a new Light Diagnostics and the CMV Brite to an in-house developed human cytomegalovirus antigenemia assay
    Elena Percivalle
    Servizio di Virologia, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy
    J Clin Virol 43:13-7. 2008
    ..Antigenemia, i.e. detection and quantification of human cytomegalovirus (HCMV) peripheral blood pp65-positive leukocytes, is still one of the two major assays available for diagnosis and monitoring of HCMV infections...
  81. doi request reprint Human cytomegalovirus tropism for endothelial/epithelial cells: scientific background and clinical implications
    M Grazia Revello
    Servizio di Virologia, Fondazione IRCCS Policlinico San Matteo, Pavia 27100, Italy
    Rev Med Virol 20:136-55. 2010
    ..However, the level of cooperation between humoral immunity and the well-established T-cell protection remains to be defined...
  82. ncbi request reprint Pathogenesis and prenatal diagnosis of human cytomegalovirus infection
    Maria Grazia Revello
    Servizio di Virologia, IRCCS Policlinico San Matteo, Pavia, Italy
    J Clin Virol 29:71-83. 2004
    ..Finally, the identification of reliable prognostic markers of fetal disease remains the ultimate goal and a major challenge...
  83. doi request reprint Clinical severity and molecular typing of human rhinovirus C strains during a fall outbreak affecting hospitalized patients
    A Piralla
    Servizio di Virologia, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy
    J Clin Virol 45:311-7. 2009
    ..The circulation rate and the clinical severity of infections caused by members of the new human rhinovirus C (HRV-C) species remain to be defined...
  84. ncbi request reprint Z-isomers of 2-hydroxymethylcyclopropylidenemethyl adenine (synadenol) and guanine (synguanol) are active against ganciclovir- and foscarnet-resistant human cytomegalovirus UL97 mutants
    Fausto Baldanti
    Servizio di Virologia, IRCCS Policlinico S Matteo, 27100 Pavia, Italy
    Antiviral Res 56:273-8. 2002
    ....
  85. ncbi request reprint Diagnostic and prognostic value of human cytomegalovirus load and IgM antibody in blood of congenitally infected newborns
    M G Revello
    Servizio di Virologia, IRCCS Policlinico San Matteo, Pavia, Italy
    J Clin Virol 14:57-66. 1999
    ..However, very little is known about the presence, levels and duration of HCMV pp65 antigenemia, viremia and DNAemia in congenitally infected newborns...
  86. ncbi request reprint Human cytomegalovirus in blood of immunocompetent persons during primary infection: prognostic implications for pregnancy
    M G Revello
    Institute of Infectious Diseases, University of Pavia, IRCCS Policlinico San Matteo, Italy
    J Infect Dis 177:1170-5. 1998
    ..Invasive procedures in the presence of maternal leukoDNAemia did not seem to interfere with vertical transmission of HCMV infection...
  87. doi request reprint Human cytomegalovirus-specific memory CD8+ and CD4+ T cell differentiation after primary infection
    Daniele Lilleri
    Servizio di Virologia, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy
    J Infect Dis 198:536-43. 2008
    ..The development of human cytomegalovirus (HCMV)-specific T cell immunity after primary infection and its correlation with virus transmission to the fetus were investigated...
  88. pmc Phylogenetic patterns of human respiratory picornavirus species, including the newly identified group C rhinoviruses, during a 1-year surveillance of a hospitalized patient population in Italy
    Antonio Piralla
    S S Virologia Molecolare, S C Virologia e Microbiologia, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy
    J Clin Microbiol 49:373-6. 2011
    ..Sequencing of the picornavirus VP4/VP2 region allowed molecular typing of HRV-A and HRV-B and provisional typing of HRV-C...
  89. ncbi request reprint Mutations in the UL97 ORF of ganciclovir-resistant clinical cytomegalovirus isolates differentially affect GCV phosphorylation as determined in a recombinant vaccinia virus system
    Fausto Baldanti
    Servizio di Virologia, IRCCS Policlinico S Matteo, 27100 Pavia, Italy
    Antiviral Res 54:59-67. 2002
    ..3 and 5.2%). Mutations in a region homologous to the domain IX had a lower impact on GCV phosphorylation (15.8-51.8%). The relevance of pUL97 mutation G598S in inducing GCV resistance was demonstrated for the first time...
  90. ncbi request reprint Multicenter quality control study for human cytomegalovirus DNAemia quantification
    Daniele Lilleri
    Servizio di Virologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    New Microbiol 32:245-53. 2009
    ..Based on these data, standardized cutoffs established for pre-emptive therapy in different transplantation centers should provide comparable clinical and virological results among centers...
  91. ncbi request reprint Diagnosis and outcome of preconceptional and periconceptional primary human cytomegalovirus infections
    Maria Grazia Revello
    Servizio di Virologia, Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy
    J Infect Dis 186:553-7. 2002
    ..Periconceptional primary HCMV infection seems to bear a higher risk of unfavorable outcome than preconceptional infection, and counseling should be adjusted accordingly...
  92. ncbi request reprint Infusion of autologous Epstein-Barr virus (EBV)-specific cytotoxic T cells for prevention of EBV-related lymphoproliferative disorder in solid organ transplant recipients with evidence of active virus replication
    Patrizia Comoli
    Department of Pediatrics, Immunology Laboratory, IRCCS Policlinico S Matteo, P le Golgi 2, 27100 Pavia, Italy
    Blood 99:2592-8. 2002
    ..This approach may, therefore, be safely used as prophylaxis of EBV-related lymphoproliferative disorders in these patients, following a strategy of preemptive therapy guided by EBV DNA levels...
  93. ncbi request reprint Human cytomegalovirus resistance to antiviral drugs: diagnosis, monitoring and clinical impact
    Fausto Baldanti
    Servizio di Virologia, IRCCS Policlinico San Matteo, 27100 Pavia, Italy
    J Antimicrob Chemother 52:324-30. 2003
    ....
  94. pmc Rising levels of human cytomegalovirus (HCMV) antigenemia during initial antiviral treatment of solid-organ transplant recipients with primary HCMV infection
    G Gerna
    Viral Diagnostic Service, IRCCS Policlinico San Matteo, Pavia, Italy
    J Clin Microbiol 36:1113-6. 1998
    ..043). Thus, shifting to an alternative antiviral drug based solely on increasing antigenemia levels is not justified in this group of patients...
  95. ncbi request reprint Analysis of HIV drug-resistant quasispecies in plasma, peripheral blood mononuclear cells and viral isolates from treatment-naive and HAART patients
    S Paolucci
    Servizio di Virologia, IRCCS Policlinico S. Matteo, Italy
    J Med Virol 65:207-17. 2001
    ..These findings may have important implications in the understanding of the selection process of drug-resistant variants under drug pressure...
  96. pmc Comparative analysis of human cytomegalovirus-specific CD4(+) T-cell frequency and lymphoproliferative response in human immunodeficiency virus-positive patients
    G Piccinini
    Servizio di Virologia, IRCCS Policlinico San Matteo, Pavia, Italy
    Clin Diagn Lab Immunol 8:1225-30. 2001
    ..It could facilitate wider screening of anti-HCMV T-helper activity in HIV-infected patients, with potential benefits for clinicians in deciding strategies of discontinuation or maintenance of anti-HCMV therapy...
  97. ncbi request reprint Human cytomegalovirus immediate-early messenger RNA in blood of pregnant women with primary infection and of congenitally infected newborns
    M G Revello
    Servizio di Virologia, Istituto di Ricovero e Cura a Carattere Scientifico, Policlinico San Matteo, 27100 Pavia, Italy
    J Infect Dis 184:1078-81. 2001
    ..IEmRNA was not detected in HCMV-immune individuals with remote or recurrent HCMV infection or in uninfected newborns. IEmRNA determination appears to be a valuable tool for early diagnosis of both primary and congenital HCMV infection...
  98. ncbi request reprint The immunosuppression and potential for EBV reactivation of fludarabine combined with cyclophosphamide and dexamethasone in patients with lymphoproliferative disorders
    M Lazzarino
    Institute of Haematology, University of Pavia, Division of Haematology, IRCCS Policlinico S Matteo, Pavia, Italy
    Br J Haematol 107:877-82. 1999
    ..T-cell dysfunction, however, is not associated with higher incidence of clinical opportunistic infections and does not adversely influence clinical outcome...
  99. ncbi request reprint Inconsistent responses of cytomegalovirus-specific T cells to pp65 and IE-1 versus infected dendritic cells in organ transplant recipients
    D Lilleri
    Servizio di Virologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    Am J Transplant 7:1997-2005. 2007
    ..In conclusion, the use of pp65 and IE-1 peptide mixtures for rapid monitoring of HCMV-specific T-cell responses in solid organ transplant recipients underestimates the actual T-cell immune response against HCMV...
  100. ncbi request reprint Changing circulation rate of human metapneumovirus strains and types among hospitalized pediatric patients during three consecutive winter-spring seasons. Brief report
    G Gerna
    Servizio di Virologia, IRCCS Policlinico San Matteo, Pavia, Italy
    Arch Virol 150:2365-75. 2005
    ..In conclusion, the 4 hMPV subtypes circulated yearly in Northern Italy flanking hRSV as major respiratory pathogens in the infantile patient population...
  101. ncbi request reprint Incidence of human cytomegalovirus infection in patients with refractory solid tumors receiving nonmyeloablative allogeneic stem cell transplants versus recipients of standard SCT for hematologic malignancies
    A Zambelli
    U O Oncologia Medica I, IRCCS, Fondazione Salvatore Maugeri, Pavia, Italy
    Biol Blood Marrow Transplant 11:423-8. 2005
    ..001) and earlier ( P = .001) than in NST patients. Patients affected with solid tumors undergoing NST had a reduced and delayed incidence of HCMV active infection...