Angelo Gatta

Summary

Affiliation: University of Padova
Country: Italy

Publications

  1. doi request reprint Hypoalbuminemia
    Angelo Gatta
    Department of Medicine, University of Padova, Padua, Italy
    Intern Emerg Med 7:S193-9. 2012
  2. ncbi request reprint Vasoactive factors and hemodynamic mechanisms in the pathophysiology of portal hypertension in cirrhosis
    Angelo Gatta
    Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Mol Aspects Med 29:119-29. 2008
  3. ncbi request reprint Hepatitis C virus reinfection in liver transplant patients: evaluation of liver damage progression with echo-color Doppler
    Massimo Bolognesi
    Department of Clinical and Experimental Medicine, University of Padua, Padua, Italy
    Liver Transpl 14:616-24. 2008
  4. doi request reprint Increased myoendothelial gap junctions mediate the enhanced response to epoxyeicosatrienoic acid and acetylcholine in mesenteric arterial vessels of cirrhotic rats
    Massimo Bolognesi
    Department of Clinical and Experimental Medicine, University of Padua, Padua, Italy
    Liver Int 31:881-90. 2011
  5. ncbi request reprint Carbon monoxide-mediated activation of large-conductance calcium-activated potassium channels contributes to mesenteric vasodilatation in cirrhotic rats
    Massimo Bolognesi
    Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
    J Pharmacol Exp Ther 321:187-94. 2007
  6. ncbi request reprint Mesenteric arteries responsiveness to acute variations of wall shear stress is impaired in rats with liver cirrhosis
    Anna Piva
    Clinica Medica 5, Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
    Scand J Gastroenterol 47:1003-13. 2012
  7. pmc IgM-linked SerpinB3 and SerpinB4 in sera of patients with chronic liver disease
    Alessandra Biasiolo
    Department of Medicine, University of Padova, Padova, Italy
    PLoS ONE 7:e40658. 2012
  8. ncbi request reprint Central nervous system alterations in liver cirrhosis: the role of portal-systemic shunt and portal hypoperfusion
    Franco Del Piccolo
    Clinica Medica 5, Department of Clinical and Experimental Medicine, University and Azienda Ospedaliera of Padova, Italy
    Metab Brain Dis 18:51-62. 2003
  9. doi request reprint Increased Th1 immune response in SERPINB3 transgenic mice during acute liver failure
    Gianmarco Villano
    Clinica Medica 5, Department of Medicine, University of Padova, Via Giustiniani, 2 35128 Padova
    Exp Biol Med (Maywood) 237:1474-82. 2012
  10. ncbi request reprint Acute liver rejection: accuracy and predictive values of doppler US measurements--initial experience
    Massimo Bolognesi
    Department of Clinical and Experimental Medicine, Institute of General Surgery, Clinica Medica 5, Policlinico Universitario, University of Padua, Via Giustiniani 2, 35128 Padua, Italy
    Radiology 235:651-8. 2005

Detail Information

Publications74

  1. doi request reprint Hypoalbuminemia
    Angelo Gatta
    Department of Medicine, University of Padova, Padua, Italy
    Intern Emerg Med 7:S193-9. 2012
    ....
  2. ncbi request reprint Vasoactive factors and hemodynamic mechanisms in the pathophysiology of portal hypertension in cirrhosis
    Angelo Gatta
    Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Mol Aspects Med 29:119-29. 2008
    ..Understanding the pathogenesis of portal hypertension could be of great utility in preventing and curing the complications of portal hypertension, such as esophageal varices, hepatic encephalopathy, ascites...
  3. ncbi request reprint Hepatitis C virus reinfection in liver transplant patients: evaluation of liver damage progression with echo-color Doppler
    Massimo Bolognesi
    Department of Clinical and Experimental Medicine, University of Padua, Padua, Italy
    Liver Transpl 14:616-24. 2008
    ..In conclusion, the information obtainable from splanchnic Doppler parameters can be used to monitor the progression of liver fibrosis in transplant patients with HCV reinfection...
  4. doi request reprint Increased myoendothelial gap junctions mediate the enhanced response to epoxyeicosatrienoic acid and acetylcholine in mesenteric arterial vessels of cirrhotic rats
    Massimo Bolognesi
    Department of Clinical and Experimental Medicine, University of Padua, Padua, Italy
    Liver Int 31:881-90. 2011
    ..Cirrhotic portal hypertension is characterized by mesenteric arterial vasodilation and hyporeactivity to vasoconstrictors...
  5. ncbi request reprint Carbon monoxide-mediated activation of large-conductance calcium-activated potassium channels contributes to mesenteric vasodilatation in cirrhotic rats
    Massimo Bolognesi
    Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
    J Pharmacol Exp Ther 321:187-94. 2007
    ....
  6. ncbi request reprint Mesenteric arteries responsiveness to acute variations of wall shear stress is impaired in rats with liver cirrhosis
    Anna Piva
    Clinica Medica 5, Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
    Scand J Gastroenterol 47:1003-13. 2012
    ..The aim of this study was to assess the vasodilation induced by wall shear stress (WSS) and acute changes in blood flow in the mesenteric arteries in an experimental model of liver cirrhosis...
  7. pmc IgM-linked SerpinB3 and SerpinB4 in sera of patients with chronic liver disease
    Alessandra Biasiolo
    Department of Medicine, University of Padova, Padova, Italy
    PLoS ONE 7:e40658. 2012
    ..As reported, high levels of circulating SCCA-IgM immunocomplexes in patients with cirrhosis are significantly associated with HCC development...
  8. ncbi request reprint Central nervous system alterations in liver cirrhosis: the role of portal-systemic shunt and portal hypoperfusion
    Franco Del Piccolo
    Clinica Medica 5, Department of Clinical and Experimental Medicine, University and Azienda Ospedaliera of Padova, Italy
    Metab Brain Dis 18:51-62. 2003
    ..In conclusion, portal liver hypoperfusion and decreased liver function were associated with an increased risk of CNSD in cirrhotic patients, whereas PUV patency per se was not...
  9. doi request reprint Increased Th1 immune response in SERPINB3 transgenic mice during acute liver failure
    Gianmarco Villano
    Clinica Medica 5, Department of Medicine, University of Padova, Via Giustiniani, 2 35128 Padova
    Exp Biol Med (Maywood) 237:1474-82. 2012
    ..In conclusion, in acute liver failure SERPINB3 determines an enhanced inflammatory background, mainly mediated by higher levels of Th1 proinflammatory cytokines...
  10. ncbi request reprint Acute liver rejection: accuracy and predictive values of doppler US measurements--initial experience
    Massimo Bolognesi
    Department of Clinical and Experimental Medicine, Institute of General Surgery, Clinica Medica 5, Policlinico Universitario, University of Padua, Via Giustiniani 2, 35128 Padua, Italy
    Radiology 235:651-8. 2005
    ....
  11. ncbi request reprint Different hemodynamic patterns of alcoholic and viral endstage cirrhosis: analysis of explanted liver weight, degree of fibrosis and splanchnic Doppler parameters
    Massimo Bolognesi
    Department of Clinical and Experimental Medicine, University of Padua, Italy
    Scand J Gastroenterol 42:256-62. 2007
    ..The objective of this study was to investigate the role of the etiology of liver disease on the relationship between liver blood flow and liver pathology in endstage cirrhosis...
  12. ncbi request reprint Detection of minimal hepatic encephalopathy: normalization and optimization of the Psychometric Hepatic Encephalopathy Score. A neuropsychological and quantified EEG study
    Piero Amodio
    Department of Clinical and Experimental Medicine, CIRMANMEC, University of Padua, Via Giustiniani, 2, 35128 Padua, Italy
    J Hepatol 49:346-53. 2008
    ..We aimed at standardizing PHES in Italy and comparing Italian, German and Spanish norms in EEG characterized cirrhotic patients...
  13. doi request reprint SERPINB3 modulates TGF-beta expression in chronic liver disease
    Cristian Turato
    I O V IRCCS, Padua, Italy
    Lab Invest 90:1016-23. 2010
    ..In conclusion, chronically damaged hepatocytes produce SERPINB3 and TGF-beta, and the anti-protease activity of this serpin might be implicated in TGF-beta1 induction...
  14. doi request reprint Excessive daytime sleepiness and hepatic encephalopathy: it is worth asking
    Michele De Rui
    Department of Medicine, University of Padova, Padova, Italy
    Metab Brain Dis 28:245-8. 2013
    ..These data support the appropriateness of adding a yes/no question on the presence of excessive daytime sleepiness to routine assessment of patients with cirrhosis, to help identify those who do not need further, formal HE screening...
  15. doi request reprint 11,12-EET increases porto-sinusoidal resistance and may play a role in endothelial dysfunction of portal hypertension
    David Sacerdoti
    Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, 35100 Padova, Italy
    Prostaglandins Other Lipid Mediat 96:72-5. 2011
    ..In conclusion, 20HETE and EETs increase portal resistance; EETs, but not 20-HETE, mediate in part the pressure response to ET-1 in the portal circulation and may be involved in pathophysiology of portal hypertension...
  16. ncbi request reprint Improving the inhibitory control task to detect minimal hepatic encephalopathy
    Piero Amodio
    Department of Clinical and Experimental Medicine, University of Padua, Padua, Italy
    Gastroenterology 139:510-8, 518.e1-2. 2010
    ..We assessed the efficacy of ICT compared with recommended diagnostic standards...
  17. doi request reprint Clinical significance of worsening portal hypertension during long-term medical treatment in patients with cirrhosis who had been classified as early good-responders on haemodynamic criteria
    Carlo Merkel
    Department of Clinical and Experimental Medicine, University of Padua, Italy
    J Hepatol 52:45-53. 2010
    ..However, it is not known whether the effect remains unchanged over the treatment period...
  18. doi request reprint How to improve care in outpatients with cirrhosis and ascites: a new model of care coordination by consultant hepatologists
    Filippo Morando
    Department of Medicine, DIMED, Italy
    J Hepatol 59:257-64. 2013
    ....
  19. doi request reprint Evaluation of the Acute Kidney Injury Network criteria in hospitalized patients with cirrhosis and ascites
    Salvatore Piano
    Department of Medicine DIMED, University of Padova, Padova, Italy
    J Hepatol 59:482-9. 2013
    ..AKIN stage 1 was defined as an increase in sCr ≥ 0.3mg/dl or increase in sCr ≥ 1.5-fold to 2-fold from baseline. AKI diagnosed with the two different criteria was evaluated for the prediction of in-hospital mortality...
  20. doi request reprint Severe acute hepatitis B in a treatment-naïve patient with antiviral drug resistant mutations in the polymerase gene
    Filippo Morando
    Department of Medicine, DIMED, University of Padova, Italy
    J Med Virol 85:210-3. 2013
    ..Finally, this case report seems to support the use of tenofovir for the immediate treatment of severe acute hepatitis B...
  21. doi request reprint Simple tools for complex syndromes: a three-level difficulty test for hepatic encephalopathy
    Sara Montagnese
    Department of Medicine, University of Padova, Padova, Italy
    Dig Liver Dis 44:957-60. 2012
    ..Despite the impact of hepatic encephalopathy on quality of life and prognosis, easily administered tests for its diagnosis are still lacking...
  22. doi request reprint Increased EETs participate in peripheral endothelial dysfunction of cirrhosis
    David Sacerdoti
    Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, 35100 Padova, Italy
    Prostaglandins Other Lipid Mediat 98:129-32. 2012
    ..In conclusion, EETs participate in the control of peripheral circulation of normal subjects and in the pathophysiology of peripheral vasodilatation of cirrhotic patients with ascites...
  23. doi request reprint Heme oxygenase regulates renal arterial resistance and sodium excretion in cirrhotic rats
    Marco Di Pascoli
    Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
    J Hepatol 54:258-64. 2011
    ..The aim of this study was to verify the role played by HO in regulating renal arterial resistance and Na(+) excretion in cirrhosis...
  24. doi request reprint Different biochemical correlates for different neuropsychiatric abnormalities in patients with cirrhosis
    Sara Montagnese
    Department of Clinical and Experimental Medicine, University of Padua, Padua, Italy
    Hepatology 53:558-66. 2011
    ..Seven patients were lost to follow-up; of the remaining 65, 20 died and 14 underwent transplantation; 15 developed HE requiring hospitalization. PHES and EEG performance were independent predictors of HE and death (P < 0.05)...
  25. doi request reprint The hunter and the pianist: two hepatic encephalopathy tales
    Sara Montagnese
    Department of Clinical and Experimental Medicine, University of Padua, Italy
    J Clin Gastroenterol 45:563-6. 2011
    ..A prospective study with accurate history taking, use of comprehensive assessment protocols, and modeling/critical interpretation of the test results is required to confirm this hypothesis...
  26. ncbi request reprint Sleep-wake abnormalities in patients with cirrhosis
    Sara Montagnese
    Department of Medicine, University of Padova, Italy
    Hepatology 59:705-12. 2014
    ..A separate section will cover the available information on their pathophysiology. Finally, etiological treatment will be briefly discussed...
  27. doi request reprint Continuous recurrence of type 1 hepatorenal syndrome and long-term treatment with terlipressin and albumin: a new exception to MELD score in the allocation system to liver transplantation?
    Salvatore Piano
    Department of Clinical and Experimental Medicine, University of Padova, Italy
    J Hepatol 55:491-6. 2011
    ..Subsequent recurrence of type 1 hepatorenal syndrome may require long-term treatment with terlipressin and albumin...
  28. doi request reprint Splenic Doppler impedance indices estimate splenic congestion in patients with right-sided or congestive heart failure
    Massimo Bolognesi
    Department of Clinical and Experimental Medicine, University of Padua, Padua, Italy
    Ultrasound Med Biol 38:21-7. 2012
    ..011) (34 patients). In conclusion, splenic PI is a measurement of splenic congestion caused by an increase in venous outflow resistance. It can estimate splenic congestion in patients with right-sided or congestive heart failure...
  29. ncbi request reprint SERPINB3 induces epithelial-mesenchymal transition
    Santina Quarta
    Department of Clinical and Experimental Medicine, University of Padova, Italy
    J Pathol 221:343-56. 2010
    ....
  30. ncbi request reprint Attention dysfunction in cirrhotic patients: an inquiry on the role of executive control, attention orienting and focusing
    Piero Amodio
    Department of Clinical and Experimental Medicine, Cirmanmec University of Padova, Italy
    Metab Brain Dis 20:115-27. 2005
    ..8, p < 0.06]. In contrast, attention orienting and focusing were maintained. In conclusion, the AAS is more sensitive than the PAS to the early stages of hepatic encephalopathy...
  31. ncbi request reprint The role of nitric oxide in the pathogenesis of systemic and splanchnic vasodilation in cirrhotic rats before and after the onset of ascites
    Paolo Angeli
    Department of Clinical and Experimental Medicine, University of Padua, Via Giustiniani 2, Padova 35100, Italy
    Liver Int 25:429-37. 2005
    ..The role of nitric oxide (NO) in the pathogenesis of splanchnic arterial vasodilation in cirrhosis has been recently debated by some experimental studies...
  32. ncbi request reprint Central nervous system alterations in liver cirrhosis: the role of portal-systemic shunt and portal hypoperfusion
    Franco Del Piccolo
    Department of Clinical and Experimental Medicine, Clinica Medica 5, University and Azienda Ospedaliera of Padova, Italy
    Metab Brain Dis 17:347-58. 2002
    ..In conclusion, portal liver hypoperfusion and decreased liver function were associated with an increased risk of central nervous system dysfunction in cirrhotic patients, whereas PUV patency per se was not...
  33. ncbi request reprint Cognitive impairment and electroencephalographic alterations before and after liver transplantation: What is reversible?
    Francesca Campagna
    Department of Medicine, University of Padua, Padua, Italy
    Liver Transpl 20:977-86. 2014
    ..Liver Transpl 20:977-986, 2014. © 2014 AASLD. ..
  34. ncbi request reprint Rat mesenteric arterial dilator response to 11,12-epoxyeicosatrienoic acid is mediated by activating heme oxygenase
    David Sacerdoti
    Dept of Clinical and Experimental Medicine, Univ of Padova, Italy, Via Giustiniani 2, 35100 Padova, Italy
    Am J Physiol Heart Circ Physiol 291:H1999-2002. 2006
    ..We conclude that the rat mesenteric vasodilator action of 11,12-EET is mediated via an increase in HO activity and an activation of calcium-activated potassium channels...
  35. ncbi request reprint Top-down and bottom-up processes in the extrastriate cortex of cirrhotic patients: an ERP study
    Sami Schiff
    Department of Clinical and Experimental Medicine, University of Padua, Via Giustiniani, 2, 35128, Padova, Italy
    Clin Neurophysiol 117:1728-36. 2006
    ..This study aims to evaluate the efficiency of top-down and bottom-up processes in the extrastriate cortex of cirrhotic patients without overt hepatic encephalopathy (HE)...
  36. pmc Hepatic progenitor cells express SerpinB3
    Gianmarco Villano
    Department of Medicine DIMED, University of Padua, Via Giustiniani 2, Padua 35128, Italy
    BMC Cell Biol 15:5. 2014
    ..Liver cDNA was amplified using specific primers for mouse-homologous SerpinB3 isoforms and automatically sequenced...
  37. ncbi request reprint Renal failure and bacterial infections in patients with cirrhosis: epidemiology and clinical features
    Silvano Fasolato
    Department of Clinical and Experimental Medicine, General Hospital and University of Padova, Padova, Italy
    Hepatology 45:223-9. 2007
    ..A progressive form of renal failure occurs only as a consequence of biliary or gastrointestinal tract infections, SBP, and UTI...
  38. doi request reprint Monoclonal gammopathy after liver transplantation: a risk factor for long-term medical complications other than malignancies
    Alessandra Galioto
    Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
    Transpl Int 25:25-33. 2012
    ..Permanent MGUS after LT does not entail a significant risk of malignancy, but it is associated with a higher risk of serious infections and CKD...
  39. ncbi request reprint Progressive increase of SCCA-IgM immune complexes in cirrhotic patients is associated with development of hepatocellular carcinoma
    Patrizia Pontisso
    Clinica Medica 5, Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
    Int J Cancer 119:735-40. 2006
    ....
  40. doi request reprint Nifedipine versus carvedilol in the treatment of de novo arterial hypertension after liver transplantation: results of a controlled clinical trial
    Alessandra Galioto
    Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
    Liver Transpl 14:1020-8. 2008
    ..In responders to carvedilol, but not in responders to nifedipine, the daily dose of tacrolimus at 1 year should be reduced to 50% compared to the baseline dose to maintain the blood trough level in the therapeutic range...
  41. ncbi request reprint Assessment of alcohol consumption in liver transplant candidates and recipients: the best combination of the tools available
    Salvatore Piano
    Department of Medicine, University of Padua, Padua, Italy
    Liver Transpl 20:815-22. 2014
    ..In conclusion, the combination of AUDIT-c and uEtG improves the detection of alcohol consumption in LTCs and LTRs. Therefore, they should be used routinely for these patients...
  42. doi request reprint SERPINB3 expression on B-cell surface in autoimmune diseases and hepatitis C virus-related chronic liver infection
    Laura Vidalino
    Department of Medicine, University of Padua, Via Giustiniani 2, Italy
    Exp Biol Med (Maywood) 237:793-802. 2012
    ..These results may suggest a role for SERPINB3 in B-cell defects typically found in viral infections and autoimmune disorders...
  43. doi request reprint Over-expression of SERPINB3 in hepatoblastoma: a possible insight into the genesis of this tumour?
    Cristian Turato
    Istituto Oncologico Veneto IOV IRCCS, Padua, Italy
    Eur J Cancer 48:1219-26. 2012
    ....
  44. ncbi request reprint Profiles of HCV core protein and viremia in chronic hepatitis C: possible protective role of core antigen in liver damage
    Alessandro Carabaich
    Clinica Medica 5, Department of Clinical and Experimental Medicine, University of Padova, Italy
    J Med Virol 76:55-60. 2005
    ..The finding of an excess of lipid-associated core particles in a subset of viremic patients without biochemical activity of liver disease suggests their protective effect in liver cell damage...
  45. ncbi request reprint Alterations in thyroid Doppler arterial resistance indices, volume and hormones in cirrhosis: relationships with splanchnic haemodynamics
    Luisa Spadaro
    Department of Clinical and Experimental Medicine, Azienda Ospedaliera and University of Padua, Padua, Italy
    Ultrasound Med Biol 30:19-25. 2004
    ..01). In conclusion, thyroid is involved, primarily and secondarily, in the haemodynamic alterations of cirrhosis; a reduction in vasodilator FT3 may play a role in the pathophysiology...
  46. ncbi request reprint SERPINB3, apoptosis and autoimmunity
    Laura Vidalino
    Clinica Medica 5, Department of Clinical and Experimental Medicine, University of Padua, Italy
    Autoimmun Rev 9:108-12. 2009
    ..Since defective programmed cell death represents a critical feature of autoimmunity, the involvement of SERPINB3 in this pathological field deserves further studies...
  47. doi request reprint The effect of aging on auditory components of event-related brain potentials
    Sami Schiff
    Department of Clinical and Experimental Medicine, University of Padua, Via Giustiniani, 2, 35128 Padua, Italy CIRMANMEC, University of Padua, Italy
    Clin Neurophysiol 119:1795-802. 2008
    ..To describe auditory perceptual, pre-attentive, attention-related and cognitive processes along lifespan in normal people by a simple auditory oddball paradigm easily usable in clinical practice...
  48. ncbi request reprint Role of squamous cell carcinoma antigen-1 on liver cells after partial hepatectomy in transgenic mice
    Gianmarco Villano
    Department of Clinical and Experimental Medicine, University of Padova, I 35123 Padova, Italy
    Int J Mol Med 25:137-43. 2010
    ..In conclusion, transgenic mice expressing SCCA1 showed higher liver regenerative potential compared to wild-type mice, supporting the dual role of this serpin as an anti-apoptotic and pro-proliferative stimulus for liver cells in vivo...
  49. ncbi request reprint MicroRNAs and SerpinB3 in hepatocellular carcinoma
    Cristian Turato
    Department of Medicine, University of Padua, Via Giustiniani, 2, 35128 Padua, Italy
    Life Sci 100:9-17. 2014
    ..Recent data indicate that this serpin may enhance its oncogenic potential through inhibition of several tumor suppressive miRNAs, typically described in HCC. ..
  50. ncbi request reprint Chronic hepatitis B in children after e antigen seroclearance: final report of a 29-year longitudinal study
    Flavia Bortolotti
    Fifth Medical Clinic, University of Padova, Italy
    Hepatology 43:556-62. 2006
    ..Long-term monitoring is important, as is counseling on cofactors of liver damage, such as alcohol and drug abuse...
  51. doi request reprint An abnormal gene expression of the beta-adrenergic system contributes to the pathogenesis of cardiomyopathy in cirrhotic rats
    Giulio Ceolotto
    Department of Clinical and Experimental Medicine, University of Padova Medical School, Padova, Italy
    Hepatology 48:1913-23. 2008
    ..These results indicate that overexpression of Galpha(i2), PDE2a, and RGS2 down-regulates the beta-adrenergic signaling pathway, thus contributing to the pathogenesis of cirrhotic cardiomyopathy...
  52. ncbi request reprint Spontaneous bacterial peritonitis due to carbapenemase-producing Klebsiella pneumoniae: the last therapeutic challenge
    Salvatore Piano
    Department of Medicine, Unit of Hepatic Emergencies and Liver Transplantation, University of Padova, Padova, Italy
    Eur J Gastroenterol Hepatol 24:1234-7. 2012
    ..In this setting, we report the first case of nosocomial spontaneous bacterial peritonitis due to carbapenemase-producing K. pneumoniae...
  53. ncbi request reprint Characteristics of minimal hepatic encephalopathy
    Piero Amodio
    Clinica Medica 5, CIRMANMEC, University of Padova, Italy
    Metab Brain Dis 19:253-67. 2004
    ..The presence of minimal hepatic encephalopathy is not without clinical consequence; it has a detrimental effect on health-related quality of life, the ability to perform complex tasks such as driving, and on outcome...
  54. pmc Role of HO/CO in the Control of Peripheral Circulation in Humans
    David Sacerdoti
    Department of Clinical and Experimental Medicine, Clinica Medica 5, University of Padova, Via Giustiniani 2, 35100 Padova, Italy
    Int J Hypertens 2012:236180. 2012
    ..In conclusion, HO/CO participates in the control of peripheral circulation, independently from NO, and is involved in vasodilatation to ACh...
  55. ncbi request reprint Neurophysiological investigation of hepatic encephalopathy
    Piero Amodio
    Clinical Medicine 5 Department of Clinical and Experimental Medicine and CIRMANMEC, University of Padova, Padova, Italy
    Metab Brain Dis 20:369-79. 2005
    ..The rationale for the use of each of these tools together with their theoretical and practical role is reviewed...
  56. ncbi request reprint 11,12-epoxyeicosatrienoic acid stimulates heme-oxygenase-1 in endothelial cells
    David Sacerdoti
    Department of Clinical and Experimental Medicine, Clinica Medica 5, University of Padova, Via Giustiniani 2, 35100 Padova, Italy
    Prostaglandins Other Lipid Mediat 82:155-61. 2007
    ..These findings identify a novel effect of EETs on endothelial HO-1 and indicate that the signaling pathway of EETs in endothelial cells is possibly via an increase in HO-1 expression and activity...
  57. ncbi request reprint Role of cytochrome P450-dependent arachidonic acid metabolites in liver physiology and pathophysiology
    David Sacerdoti
    Department of Clinical and Experimental Medicine, Azienda Ospedaliera and University of Padova, Clinica Medica 5, Via Giustiniani 2, 35100 Padova, Italy
    Prostaglandins Other Lipid Mediat 72:51-71. 2003
    ..They appear to be deeply involved in abnormalities related to liver diseases, particularly cirrhosis, and play a key role in the pathophysiology of portal hypertension and renal failure...
  58. ncbi request reprint Biological and clinical implications of HBV infection in peripheral blood mononuclear cells
    Patrizia Pontisso
    Clinica Medica 5, Department of Clinical and Experimental Medicine, University of Padua, Italy
    Autoimmun Rev 8:13-7. 2008
    ..HBV can also infect bone marrow cells and in vitro studies demonstrate a block of hematopoiesis by HBV, supporting clinical observations of isolate cases of aplastic anemia associated to the infection...
  59. doi request reprint Barcelona Clinic Liver Cancer staging and transplant survival benefit for patients with hepatocellular carcinoma: a multicentre, cohort study
    Alessandro Vitale
    Unità di Chirurgia Epatobiliare e Trapianto Epatico, Azienda Ospedaliera, Universita di Padova, Padova, Italy
    Lancet Oncol 12:654-62. 2011
    ..We aimed to create a prediction model linking the BCLC stage of patients with hepatocellular carcinoma to their 5-year liver transplant benefit...
  60. ncbi request reprint Olfactory deficits in patients affected by minimal hepatic encephalopathy: a pilot study
    Gesualdo M Zucco
    Department of General Psychology, University of Padua, Padova, Italy
    Chem Senses 31:273-8. 2006
    ..This pattern supports the notion that olfactory alterations related to cognitive dysfunction in patients with MHE may be linked to the pathophysiology of HE...
  61. ncbi request reprint Parenchymal transforming growth factor beta-1: its type II receptor and Smad signaling pathway correlate with inflammation and fibrosis in chronic liver disease of viral etiology
    Fiorella Calabrese
    Department of Pathology, University of Padua, Italy
    J Gastroenterol Hepatol 18:1302-8. 2003
    ..The aim of our study was to define TGF-beta system expression in hepatic parenchymal cells and its significance in patients with differing extents of chronic liver disease of viral etiology...
  62. doi request reprint Is female sex a significant favorable prognostic factor in hepatocellular carcinoma?
    Fabio Farinati
    Dipartimento di Scienze Chirurgiche e Gastroenterologiche, Università di Genova iUnità di Gastroenterologia, Ospedale Belcolle, Viterbo, Italy
    Eur J Gastroenterol Hepatol 21:1212-8. 2009
    ..As sex favorably modulates the natural history of chronic liver diseases and the risk for neoplastic evolution, our study aimed to ascertain whether female hepatocellular carcinoma (HCC) patients are also characterized by better prognosis...
  63. pmc Splanchnic vasodilation and hyperdynamic circulatory syndrome in cirrhosis
    Massimo Bolognesi
    Massimo Bolognesi, Marco Di Pascoli, Alberto Verardo, Angelo Gatta, Department of Internal Medicine DIMED, University of Padua, Azienda Ospedaliera Universita di Padova, 35128 Padova, Italy
    World J Gastroenterol 20:2555-63. 2014
    ..Understanding the pathophysiology of splanchnic vasodilatation and hyperdynamic circulatory syndrome is mandatory for the prevention and treatment of portal hypertension and its severe complications. ..
  64. ncbi request reprint Hepatitis C virus infection associated with liver-kidney microsomal antibody type 1 (LKM1) autoantibodies in children
    Flavia Bortolotti
    Department of Pediatrics, University of Padua, Padua, Italy
    J Pediatr 142:185-90. 2003
    ..To evaluate the clinical pattern and evolution of chronic hepatitis C in children with liver/kidney microsomal antibody type 1 autoantibodies (LKM1)...
  65. ncbi request reprint Prevalence of liver disease in a population of asymptomatic persons with hepatitis C virus infection
    Alfredo Alberti
    Department of Clinical and Experimental Medicine, Clinica Medica 5, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Ann Intern Med 137:961-4. 2002
    ..The prevalence of significant liver disease in persons with asymptomatic hepatitis C virus (HCV) infection is unclear...
  66. ncbi request reprint Comparison between two high-dose methylprednisolone schedules in the treatment of acute hepatic cellular rejection in liver transplant recipients: a controlled clinical trial
    Roberta Volpin
    Department of Clinical and Experimental Medicine, University of Padua, Italy
    Liver Transpl 8:527-34. 2002
    ....
  67. ncbi request reprint Role of the heme oxygenases in abnormalities of the mesenteric circulation in cirrhotic rats
    David Sacerdoti
    Department of Clinical and Experimental Medicine, University and Azienda Ospedaliera of Padova, Italy
    J Pharmacol Exp Ther 308:636-43. 2004
    ..We propose that HO is an essential component in mechanisms that modulate reactivity of the mesenteric circulation in experimental hepatic cirrhosis in rats...
  68. ncbi request reprint A placebo-controlled clinical trial of nadolol in the prophylaxis of growth of small esophageal varices in cirrhosis
    Carlo Merkel
    Department of Clinical and Experimental Medicine, University of Padua, Padova, Italy
    Gastroenterology 127:476-84. 2004
    ..Beta-blockers are extensively used to prevent variceal bleeding in patients with large esophageal varices. It is not established if beta-blockers delay the growth of small varices...
  69. ncbi request reprint Change in portal flow after liver transplantation: effect on hepatic arterial resistance indices and role of spleen size
    Massimo Bolognesi
    Department of Clinical and Experimental Medicine, Institute of General Surgery, Intensive Care Unit, University of Padua, Via Giustiniani 2, 35128 Padua, Italy
    Hepatology 35:601-8. 2002
    ..A normal time course of portal-hepatic hemodynamics was detected in patients transplanted for acute liver failure...
  70. ncbi request reprint Variability of trail making test, symbol digit test and line trait test in normal people. A normative study taking into account age-dependent decline and sociobiological variables
    Piero Amodio
    Department of Clinical and Experimental Medicine, University of Padova, Italy
    Aging Clin Exp Res 14:117-31. 2002
    ..Even less is known about the reliability at re-testing. This study aimed at determining the reference range of these tests, taking into account sociobiological variables and age, and the re-testing effect...
  71. ncbi request reprint Mood, cognition and EEG changes during interferon alpha (alpha-IFN) treatment for chronic hepatitis C
    Piero Amodio
    Dipartimento di Medicina Clinica e Sperimentale, Clinica Medica 5, Policlinico Universitario, Via Giustiniani, 2, 35128, Padova, Italy
    J Affect Disord 84:93-8. 2005
    ..This study is aim to investigate concurrent long-term psychiatric, cognitive and neurophysiological measures of alpha-IFN neurotoxicity in the treatment of chronic viral hepatitis...
  72. ncbi request reprint Impairment of response inhibition precedes motor alteration in the early stage of liver cirrhosis: a behavioral and electrophysiological study
    Sami Schiff
    Department of Neurological and Vision Sciences, University of Verona, Verona, Italy
    Metab Brain Dis 20:381-92. 2005
    ..In conclusion, cirrhotic patients without overt HE display a psychomotor slowing, depending first lyon response inhibition and only later accompanied by impaired motor execution...
  73. ncbi request reprint Effect of potassium canrenoate, an anti-aldosterone agent, on incidence of ascites and variceal progression in cirrhosis
    Luigi Bolondi
    Division of Internal Medicine, Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
    Clin Gastroenterol Hepatol 4:1395-402. 2006
    ....
  74. ncbi request reprint Squamous cell carcinoma antigen-immunoglobulin M complexes as novel biomarkers for hepatocellular carcinoma
    Luca Beneduce
    Xeptagen S p A Life Biotechnology, Pozzuoli, Italy
    Cancer 103:2558-65. 2005
    ..The authors recently demonstrated that squamous cell carcinoma antigen (SCCA) variants were overexpressed remarkably in all surgically resected HCCs...