Research Topics
| Roberto GaspariniSummaryAffiliation: University of Genoa Country: Italy Publications
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Detail Information
Publications
Effectiveness of adjuvanted seasonal influenza vaccines (Inflexal V (®) and Fluad (®) ) in preventing hospitalization for influenza and pneumonia in the elderly: A matched case-control studyRoberto Gasparini
Department of Health Sciences Genoa University Genoa, Italy Inter University Centre for Research on Influenza and other Transmitted Infections CIRI IT
Hum Vaccin Immunother 9:144-52. 2013....
Neisseria meningitidis, pathogenetic mechanisms to overcome the human immune defencesR Gasparini
Department of Health Sciences, University of Genoa, Italy
J Prev Med Hyg 53:50-5. 2012..NadA is known to be involved in cell adhesion and invasion and in the induction of proinflammatory cytokines. Neisserial heparin binding antigen (NHBA) binds heparin, thus increasing the resistance of the bacterium in the serum...- Aflunov(®): a prepandemic influenza vaccineRoberto Gasparini
Department of Health Science, University of Genoa Italy, Via Pastore, 1 16132, Genoa, Italy
Expert Rev Vaccines 11:145-57. 2012..This vaccine could be very useful in the event of adaptation of the H5N1 virus to humans, which could cause a new pandemic... - Clinical and socioeconomic impact of seasonal and pandemic influenza in adults and the elderlyRoberto Gasparini
Department of Health Sciences, University of Genoa, Genova, Italy
Hum Vaccin Immunother 8:21-8. 2012..Estimating the influenza burden is a useful aid to determining the best influenza vaccination strategy and preventive and clinical treatments... - Influenza and respiratory syncytial virus in infants and children: relationship with attendance at a paediatric emergency unit and characteristics of the circulating strainsR Gasparini
Interuniversity Centre for Research on Influenza and Viral Infections CIRI IV, Department of Health Sciences, University of Genoa, Italy
Eur J Clin Microbiol Infect Dis 26:619-28. 2007..A/H3N2 strains belonged to two clusters, A/Panama/2007/99-like and A/Fujian/411/02-like, a new variant. This paper discusses the possible role of the identified flu strains in determining EUARs among the population by age class... - Human papillomavirus vaccination: what is the best choice? A comparison of 16 strategies by means of a decisional modelR Gasparini
Department of Health Sciences of Genoa University, Genoa, Italy
Epidemiol Infect 137:794-802. 2009..Indeed, it could generate interesting savings for the National Health Service and a rapid HPV immunization of young girls... 
Randomized trial on the safety, tolerability, and immunogenicity of MenACWY-CRM, an investigational quadrivalent meningococcal glycoconjugate vaccine, administered concomitantly with a combined tetanus, reduced diphtheria, and acellular pertussis vaccine Roberto Gasparini
Department of Health Sciences, University of Genoa, Via Pastore 1, 16132 Genoa, Italy
Clin Vaccine Immunol 17:537-44. 2010..These results indicate that the investigational MenACWY-CRM vaccine is well tolerated and immunogenic and that it can be coadministered with Tdap to adolescents and young adults...- Meningococcal glycoconjugate vaccinesRoberto Gasparini
Department of Health Sciences, Genoa University, Genoa, Italy
Hum Vaccin 7:170-82. 2011..This review highlights the evolution of conjugate meningococcal vaccines in general and discusses how this kind of vaccine can contribute to preventing meningococcal disease... - Live attenuated influenza vaccine--a reviewR Gasparini
Department of Health Sciences, University of Genoa, Italy
J Prev Med Hyg 52:95-101. 2011..However, a more widespread use of these vaccines is to be recommended, especially in children, as the more acceptable way of administration can favour parental compliance... - Safety and tolerability of bivalent HPV vaccine: an Italian post-licensure studyRoberto Gasparini
Department of Health Science, University of Genoa, Genoa, Italy
Hum Vaccin 7:136-46. 2011..That tolerability proved to be better than in clinical studies could be explained by the absence of the typical apprehension felt by subjects involved in clinical experimentation... - Cost-benefit evaluation of influenza vaccination in the elderly in the Italian region of LiguriaR Gasparini
Section of Hygiene and Preventive Medicine, Department of Health Sciences, University of Genoa, Via Pastore 1, 16132 Genova, Italy
Vaccine 20:B50-4. 2002..We were also able to establish that the vaccine coverage among elderly individuals was 63%. Our study, though carried out during a low epidemic year, confirms the economic advantage of vaccination in the elderly... - Seroprevalence of bactericidal antibody against Neisseria meningitidis serogroup C in pre-vaccinal era: the Italian epidemiological scenarioR Gasparini
Department of Health Sciences, University of Genoa, Via Pastore 1, 16132 Genoa, Italy
Vaccine 27:3435-8. 2009..High titres were observed in 3-, 8-, 9- and 17-year-old subjects. Our results therefore indicate that meningococcus C has the highest probability of spreading among 1-4, 8-10 and 14-17-year-old subjects in Italy... - Cross-protection by MF59-adjuvanted influenza vaccine: neutralizing and haemagglutination-inhibiting antibody activity against A(H3N2) drifted influenza virusesFilippo Ansaldi
CIRI IV, Department of Health Sciences, University of Genoa, Genoa, Italy
Vaccine 26:1525-9. 2008..Thus, MF59-adjuvanted vaccine confers greater immunogenicity than non-adjuvanted vaccines in vulnerable populations... - Burden of rotavirus-associated and non-rotavirus-associated diarrhea among nonhospitalized individuals in central Italy: a 1-year sentinel-based epidemiological and virological surveillanceFilippo Ansaldi
Department of Health Sciences, University of Genoa, Genoa, Italy
Clin Infect Dis 46:e51-5. 2008..1% and 41.7%, respectively). Approximately one-third of gastroenteritis cases requiring an office visit or telephone consultation were attributable to rotavirus infection... - Neutralizing and hemagglutination-inhibiting activities of antibodies elicited by the 2004-2005 influenza vaccine against drifted virusesFilippo Ansaldi
Department of Health Sciences, University of Genoa, Via Pastore 1, 16100 Genoa, Italy
Clin Vaccine Immunol 13:162-4. 2006.... - Hepatitis A incidence and hospital-based seroprevalence in Italy: a nation-wide studyFilippo Ansaldi
Department of Health Sciences, University of Genoa, Via Pastore 1, Genoa, Italy
Eur J Epidemiol 23:45-53. 2008..In the period from 1998 to 2005, the incidence drastically decreased (average of 3.2/100,000 inhabitants), reaching a minimum of 2/100,000 inhabitants in 2005... - Molecular characterization of a new variant of rotavirus P[8]G9 predominant in a sentinel-based survey in central ItalyFilippo Ansaldi
Department of Health Sciences, University of Genoa, Via Pastore 1, 16100 Genoa, Italy
J Clin Microbiol 45:1011-5. 2007.... - Sexual behaviour and risk factors for the acquisition of human papillomavirus infections in young people in Italy: suggestions for future vaccination policiesDonatella Panatto
Department of Health Sciences, University of Genoa, Via Pastore, 1 16132, Genoa, Italy
BMC Public Health 12:623. 2012..We surveyed sexual habits among young people in order to provide information that might orient decision-makers in adopting HPV multi-cohort vaccination policies... - New A/H3N2 influenza variant: a small genetic evolution but a heavy burden on the Italian population during the 2004-2005 seasonFilippo Ansaldi
CIRI-IV, Department of Health Sciences, University of Genoa, Genoa, Italy
J Clin Microbiol 43:3027-9. 2005 - Burden of the 1999-2008 seasonal influenza epidemics in Italy: comparison with the H1N1v (A/California/07/09) pandemicPiero Luigi Lai
Department of Health Sciences, University of Genoa, Via Pastore, Genoa, Italy
Hum Vaccin 7:217-25. 2011.... - Different seroprevalence and molecular epidemiology patterns of hepatitis C virus infection in ItalyFilippo Ansaldi
Department of Health Sciences, University of Genoa, Genoa, Italy
J Med Virol 76:327-32. 2005.... - Neisseria meningitidis B vaccinesDonatella Panatto
Department of Health Sciences, University of Genoa, Via Pastore 1, 16132, Genoa, Italy
Expert Rev Vaccines 10:1337-51. 2011..The aims of this article are to describe the most recent developments in meningococcal B vaccines and to discuss how these vaccines can contribute to containing meningococcal disease... - Sexual behaviour in Ligurian (Northern Italy) adolescents and young people: suggestions for HPV vaccination policiesDonatella Panatto
Department of Health Sciences of Genoa University, Via Pastore 1, 16132 Genoa, Italy
Vaccine 27:A6-10. 2009..Our findings suggest that current HPV vaccination should be implemented by introducing new cohorts, especially young girls (14-16 years)... - Epidemiological trend in tuberculosis in the Italian region of Liguria: impact of immigration and AIDSPaolo Crimi
Department of Health Sciences, University of Genoa, Italy
Eur J Public Health 15:339-42. 2005..It is for this reason that in the last decade all industrialized countries have intensified their controls on TB and a new reduction has been recently observed... - Burden of rotavirus disease and cost-effectiveness of universal vaccination in the Province of Genoa (Northern Italy)D Panatto
Department of Health Science, University of Genoa, Via Pastore 1, 16132 Genoa, Italy
Vaccine 27:3450-3. 2009..From the perspective of both the RHS and S, vaccination proved to be highly cost-effective... - Ostreopsis ovata and human health: epidemiological and clinical features of respiratory syndrome outbreaks from a two-year syndromic surveillance, 2005-06, in north-west ItalyP Durando
Department of Health Sciences, Section of Hygiene and Preventive Medicine, San Martino Hospital, University of Genoa, Genoa, Italy
Euro Surveill 12:E070607.1. 2007 - Assessment and prevention of radioactive risk due to 222Radon on University Premises in Genoa, ItalyD Panatto
Section of Hygiene and Preventive Medicine, Department of Health Sciences, University of Genoa, Italy
J Prev Med Hyg 47:134-7. 2006..Nevertheless, the value of the compound uncertainty index suggested that the real level of Radon contamination could have exceeded 400 Bq/m3 in selected spaces, a value requiring annual concentration tests... - Public health research literature on infectious diseases: coverage and gaps in EuropeP Durando
Department of Health Sciences, Section of Hygiene and Preventive Medicine, San Martino Hospital, University of Genoa, Genoa, Italy
Eur J Public Health 17:19-23. 2007..The aim was to gain an overall view of published research on IDs in Europe as part of the collaborative study SPHERE (Strengthening Public Health Research in Europe)... - Safety and immunogenicity of two influenza virus subunit vaccines, with or without MF59 adjuvant, administered to human immunodeficiency virus type 1-seropositive and -seronegative adultsP Durando
Department of Health Sciences, University of Genoa, 16132 Genoa, Italy
Clin Vaccine Immunol 15:253-9. 2008..The results showed good safety and immunogenicity for both vaccines under study for both uninfected and HIV-1-infected adults, confirming current recommendations for immunization of this high-risk category... - Combination hepatitis C virus antigen and antibody immunoassay as a new tool for early diagnosis of infectionF Ansaldi
Department of Health Sciences, University of Genoa, Genoa, Italy
J Viral Hepat 13:5-10. 2006.... - Survey of domestic accidents in the elderly in the Province of Genoa (northern Italy)D Panatto
Department of Health Science DiSSal, University of Genoa, Italy
J Prev Med Hyg 50:53-7. 2009..The aim of the present study was to evaluate the number, characteristics and causes of domestic accidents among the elderly... - Long-term decline of 137Cs concentration in honey in the second decade after the Chernobyl accidentDonatella Panatto
DiSSal Department of Heath Sciences, University of Genoa, Via Pastore 1, 16132 Genoa, Italy
Sci Total Environ 382:147-52. 2007..Long-term decline was calculated at 456 days, a value lower than those published from different food sources in the years following the accident. The rate of long-term decline decreases with time... - Comparison between a conventional subunit vaccine and the MF59-adjuvanted subunit influenza vaccine in the elderly: an evaluation of the safety, tolerability and immunogenicityD Sindoni
Department of Hygiene, Preventive Medicine and Public Health, University of Messina, Italy Department of Health Sciences, University of Genoa, Italy
J Prev Med Hyg 50:121-6. 2009..Both vaccines were generally well tolerated; no severe adverse events occurred in any of the subjects vaccinated, confirming the excellent safety profile of Fluad and Agrippal... - Performance testing of two new one-step real time PCR assays for detection of human influenza and avian influenza viruses isolated in humans and respiratory syncytial virusL Valle
CIRI-IV, Department of Health Sciences, University of Genoa, Italy
J Prev Med Hyg 47:127-33. 2006..DISCUSSION AND CONCLUSION: The new assays provide accurate and sensitive diagnosis of influenza and RSV infection and they represent a sensitive tool for virological surveillance and management of patient with ILI... - Antigenic characterisation of influenza B virus with a new microneutralisation assay: comparison to haemagglutination and sequence analysisFilippo Ansaldi
C I R I, Department of Health Sciences, University of Genoa, Genoa, Italy
J Med Virol 74:141-6. 2004.... - Can particulate air sampling predict microbial load in operating theatres for arthroplasty?Maria Luisa Cristina
Department of Health Sciences, University of Genoa, Genoa, Italy
PLoS ONE 7:e52809. 2012..5 µm and ≥5 µm). Consequently, microbiological monitoring remains the most suitable method of evaluating the quality of air in operating theatres... - Utility of virosomal adjuvated influenza vaccines: a review of the literatureR Gasparini
Department of Health Sciences, University of Genoa, Italy
J Prev Med Hyg 51:1-6. 2010.... - Silver zeolite antimicrobial activity in aluminium heating, ventilation and air conditioning system ductsR Rizzetto
Department of Health Sciences, University of Genoa, Italy
J Prev Med Hyg 49:26-33. 2008.... - Effectiveness of a 23-valent polysaccharide vaccine in preventing pneumonia and non-invasive pneumococcal infection in elderly people: a large-scale retrospective cohort studyF Ansaldi
Department of Health Sciences, University of Genoa, Genoa, Italy
J Int Med Res 33:490-500. 2005.... - Safety and immunogenicity of conventional subunit and MF59-adjuvanted influenza vaccines in human immunodeficiency virus-1-seropositive patientsG Gabutti
Laboratory of Hygiene, Department of Biological and Environmental Sciences and Technologies, Faculty of Sciences, University of Lecce, Lecce, Italy
J Int Med Res 33:406-16. 2005..These results confirmed the safety and immunogenicity of these currently available vaccines in HIV-1-seropositive patients, thus supporting the recommendation for influenza immunization in this high-risk category... - Burden of influenza in healthy children and their householdsN Principi
Institute of Paediatrics, University of Milan, Milan, Italy
Arch Dis Child 89:1002-7. 2004..A prospective, multicentre study was conducted to evaluate the burden of laboratory confirmed influenza in healthy children and their household contacts... - Surveillance of influenza in Apulia, Italy, 1999-2000, 2000-2001, 2001-2002, and 2002-2003 seasonsG Gabutti
Laboratory of Hygiene, Department of Biological and Environmental Sciences and Technologies, Di S Te B A, Faculty of Sciences, University of Lecce, via prov le Lecce Monteroni, 73100 Lecce, Italy
Med Mal Infect 34:469-76. 2004.... - Clinical and socio-economic impact of influenza and respiratory syncytial virus infection on healthy children and their householdsS Esposito
Institute of Pediatrics, Fondazione IRCCS 'Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, University of Milan, Milan, Italy
Clin Microbiol Infect 11:933-6. 2005..The fact that influenza has a similar global clinical impact on the community to that of RSV infection, but represents a greater socio-economic burden, may contribute to broadening the acceptance of influenza vaccination... - Increased immunogenicity of the MF59-adjuvanted influenza vaccine compared to a conventional subunit vaccine in elderly subjectsR Gasparini
Institute of Hygiene, University of Siena, Italy
Eur J Epidemiol 17:135-40. 2001.... - Molecular epidemiology of measles in Liguria, Italy: a tool for the elimination of the infectionF Ansaldi
J Prev Med Hyg 48:39-42. 2007 - Drug resistance among influenza A viruses isolated in Italy from 2000 to 2005: are the emergence of Adamantane-resistant viruses cause of concern?F Ansaldi
J Prev Med Hyg 47:1-3. 2006 - Seroprevalence of HTLV-I and HTLV-II infection among immigrants in northern ItalyF Ansaldi
Department of Public Medical Sciences, University of Trieste and IRCCS Burlo Garofolo, Italy
Eur J Epidemiol 18:583-8. 2003..2 in the open population; OR: 9.9 among prisoners), whereas sexual exposure was associated with HTLV-I seropositivity only for prisoners (OR: 14.3). No independent variable was related to HTLV-II infection... - [Human papillomavirus vaccination. Consensus Conference in pediatric age]G Bartolozzi
Dipartimento di Pediatria, Universita degli Studi di Firenze, Firenze
Minerva Pediatr 59:165-82. 2007....