F Fusi

Summary

Affiliation: University of Siena
Country: Italy

Publications

  1. Fusi F, Cavalli M, Mulholland D, Crouch N, Coombes P, Dawson G, et al. Cardamonin is a bifunctional vasodilator that inhibits Ca(v)1.2 current and stimulates K(Ca)1.1 current in rat tail artery myocytes. J Pharmacol Exp Ther. 2010;332:531-40 pubmed publisher
    ..1 current, may represent a scaffold for the design of novel drugs of potential interest for treatment of systemic hypertension. ..
  2. Fusi F, Saponara S, Gagov H, Sgaragli G. Effects of some sterically hindered phenols on whole-cell Ca(2+) current of guinea-pig gastric fundus smooth muscle cells. Br J Pharmacol. 2001;132:1326-32 pubmed
    ..5. We conclude that the inhibition of I(Ca(L)) by BHA and DTBHA is qualitatively similar to that of a Ca(2+) channel blocker and is characterized by the stabilizing effect of the inactivated state of the channel...
  3. Fusi F, Ferrara A, Koorbanally C, Crouch N, Mulholland D, Sgaragli G. Vascular myorelaxing activity of isolates from South African Hyacinthaceae partly mediated by activation of soluble guanylyl cyclase in rat aortic ring preparations. J Pharm Pharmacol. 2008;60:489-97 pubmed publisher
    ..To our knowledge, this has been the first account describing the vasodilating activity of homoisoflavonoids: compound 3 proved an effective vasorelaxing agent, partly acting via the activation of soluble guanylyl cyclase...

Locale

Detail Information

Publications3

  1. Fusi F, Cavalli M, Mulholland D, Crouch N, Coombes P, Dawson G, et al. Cardamonin is a bifunctional vasodilator that inhibits Ca(v)1.2 current and stimulates K(Ca)1.1 current in rat tail artery myocytes. J Pharmacol Exp Ther. 2010;332:531-40 pubmed publisher
    ..1 current, may represent a scaffold for the design of novel drugs of potential interest for treatment of systemic hypertension. ..
  2. Fusi F, Saponara S, Gagov H, Sgaragli G. Effects of some sterically hindered phenols on whole-cell Ca(2+) current of guinea-pig gastric fundus smooth muscle cells. Br J Pharmacol. 2001;132:1326-32 pubmed
    ..5. We conclude that the inhibition of I(Ca(L)) by BHA and DTBHA is qualitatively similar to that of a Ca(2+) channel blocker and is characterized by the stabilizing effect of the inactivated state of the channel...
  3. Fusi F, Ferrara A, Koorbanally C, Crouch N, Mulholland D, Sgaragli G. Vascular myorelaxing activity of isolates from South African Hyacinthaceae partly mediated by activation of soluble guanylyl cyclase in rat aortic ring preparations. J Pharm Pharmacol. 2008;60:489-97 pubmed publisher
    ..To our knowledge, this has been the first account describing the vasodilating activity of homoisoflavonoids: compound 3 proved an effective vasorelaxing agent, partly acting via the activation of soluble guanylyl cyclase...