Detail Information
Publications
Design, synthesis and in vitro antitumour activity of new heteroaryl ethylenesCosimo G Fortuna
Dipartimento di Scienze Chimiche, Universita degli Studi di Catania, Viale A Doria 6 95125, Catania, Italy
Eur J Med Chem 47:221-7. 2012..2-{(E)-2-[5'-(Dibutylamino)-2,2'-bithien-5-yl]vinyl}-1-methylquinolinium iodide exhibited in vitro antiproliferative activity two orders of magnitude higher than that of the most active compound previously synthesized in our laboratory...
Design and synthesis of trans 2-(furan-2-yl)vinyl heteroaromatic iodides with antitumour activityCosimo Gianluca Fortuna
Dipartimento di Scienze Chimiche, Universita di Catania, Viale A Doria, 6, 95125 Catania, Italy
Bioorg Med Chem 16:4150-9. 2008..The synthesis and in vitro antitumour tests on a breast carcinoma cell line (MCF7) confirmed VOLSURF predicted activity values...
Design, synthesis and biological evaluation of trans 2-(thiophen-2-yl)vinyl heteroaromatic iodidesCosimo G Fortuna
Dipartimento di Scienze Chimiche, Universita di Catania, Viale A Doria, Catania, Italy
Bioorg Med Chem 18:4516-23. 2010..An Almond model, derived to have an overall structural insight on the above compounds, supported the validity of Volsurf and provided guidelines for the synthesis of new compounds...
Synthesis and NLO properties of new trans 2-(thiophen-2-yl)vinyl heteroaromatic iodidesCosimo Gianluca Fortuna
Dipartimento di Scienze Chimiche, Universita di Catania, Viale A Doria, 6, 95125, Catania, Italy
Org Biomol Chem 9:1608-13. 2011....
