Research Topics
Species | Annarosa FloreaniSummaryAffiliation: University of Padova Country: Italy Publications
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Detail Information
Publications
Hepatic Methionine-enkephalin may interfere with response to antiviral therapy in chronic hepatitis CAnnarosa Floreani
Department of Surgical and Gastroenterological Sciences, University of Padova, Padova, Italy
Eur J Gastroenterol Hepatol 24:427-30. 2012..Thus, it was hypothesized that liver-derived endogenous opioids, which also bind to opioid receptors, may interfere with the response to antiviral therapy with interferon...
A 4-year treatment with clodronate plus calcium and vitamin D supplements does not improve bone mass in primary biliary cirrhosisA Floreani
Department of Surgical and Gastroenterological Sciences, University of Padova, Padova, Italy
Dig Liver Dis 39:544-8. 2007..5 t-score as a cut-off for medical treatment, while no treatment is recommended in the case of osteopenia (t-scores ranging from -1.0 to -2.5)...- Long-term persistence of anti-HBs after vaccination against HBV: an 18 year experience in health care workersAnnarosa Floreani
Department of Surgical and Gastroenterological Sciences, University of Padua, Via Giustiniani 2, 35128 Padua, Italy
Vaccine 22:607-10. 2004..Overall, the anti-HBs seroprotection rate was 95.4% (102 subjects). Based on GMT results, no booster dose is necessary in healthy adults for at least 10 years after primary immunization... - Pegylated interferon alpha-2b plus ribavirin for naive patients with HCV-related cirrhosisAnnarosa Floreani
Department of Surgical and Gastroenterological Sciences, University of Padova, Padova, Italy
J Clin Gastroenterol 42:734-7. 2008..Data on the efficacy of antiviral therapy in patients with HCV-related compensated cirrhosis are generally drawn from analyzing subgroups in larger trials... - Is osteoporosis a peculiar association with primary biliary cirrhosis?Annarosa Floreani
Div Gastroenterologia, Via Giustiniani, 2, Padova 35128, Italy
World J Gastroenterol 11:5347-50. 2005.... - Hepatobiliary phospholipid transporter ABCB4, MDR3 gene variants in a large cohort of Italian women with intrahepatic cholestasis of pregnancyA Floreani
Department of Surgical and Gastroenterological Sciences, Padua University, Padova, Italy
Dig Liver Dis 40:366-70. 2008..Intrahepatic cholestasis of pregnancy is a multifactorial disorder of pregnancy associated with a genetic background... - Fatal hepatic decompensation in a bone marrow transplant recipient with HBV-related cirrhosis following lamivudine withdrawalAnnarosa Floreani
Department of Surgical and Gastroenterological Sciences, University of Padova, Italy
Gastroenterol Clin Biol 30:307-9. 2006..In conclusion, this case shows that physicians should avoid discontinuing nucleoside therapy in patients with HBV infection who undergo immunosuppression for concomitant neoplastic conditions... - Primary biliary cirrhosis: when and why does the disease develop?A Floreani
Department of Surgical and Gastroenterological Sciences, University of Padova, Padua, Italy
Dig Liver Dis 38:272-5. 2006..A temporal association between Borrelia Burgdorferi infection and diagnosis of primary biliary cirrhosis was observed... - Is hepatitis C virus a risk factor for thyroid autoimmunity?A Floreani
Department of Surgical and Gastroenterological Sciences, University of Padova, Italy
J Viral Hepat 13:272-7. 2006.... - A novel multidrug-resistance protein 2 gene mutation identifies a subgroup of patients with primary biliary cirrhosis and pruritusAnnarosa Floreani
Department of Surgical and Gastroenterological Sciences, University of Padova, Italy
Hepatology 43:1152-4. 2006..This heterozygous mutation was significantly associated with the presence of pruritus... - An open population screening study for HFE gene major mutations proves the low prevalence of C282Y mutation in Central ItalyA Floreani
Department of Surgical and Gastroenterological Sciences, University of Padu, Via Giustiniani 2, 35128 Padua, Italy
Aliment Pharmacol Ther 26:577-86. 2007..The C282Y mutation in the HFE gene is responsible for most cases of hereditary haemochromatosis... - Intrahepatic cholestasis of pregnancy: three novel MDR3 gene mutationsA Floreani
Department of Surgical and Gastroenterological Sciences, University of Padova, Padova, Italy
Aliment Pharmacol Ther 23:1649-53. 2006..The aetiology of intrahepatic cholestasis of pregnancy is unknown, but more than 10 different MDR3 gene mutations have recently been identified... - Type I autoimmune hepatitis: clinical course and outcome in an Italian multicentre studyA Floreani
Department of Surgical and Gastroenterological Sciences, University of Padova, Padova, Italy
Aliment Pharmacol Ther 24:1051-7. 2006..Many reports of autoimmune hepatitis (AIH) were written in the 'pre-Hepatitis C era' and data on the natural history are still incomplete... - Liver diseases in the elderly: an updateAnnarosa Floreani
Department of Surgical and Gastroenterological Sciences, University of Padova, Padova, Italy
Dig Dis 25:138-43. 2007..Moreover, some therapeutic approaches, especially antiviral therapy and liver transplantation, should be discussed also in selected groups of elderly patients... - Preventative therapy in primary biliary cirrhosisAnnarosa Floreani
Department of Surgical and Gastroenterological Sciences, University of Padova, Via Giustiniani, 2, 35128 Padova, Italy
Clin Liver Dis 7:911-21. 2003..For the time being, however, the only practical preventative management is in regards to the complications of PBC, namely osteopenia and portal hypertension... - Hepatic expression of endocannabinoid receptors and their novel polymorphisms in primary biliary cirrhosisAnnarosa Floreani
Department of Surgical and Gastroenterological Sciences, University of Padua, Via Giustiniani, 2, 35128 Padua, Italy
J Gastroenterol 45:68-76. 2010..The endocannabinoid system (EC) has emerged as a crucial mediator in a variety of pathophysiological conditions... - Retreatment of patients with chronic hepatitis C relapsers to a previous antiviral treatmentAnnarosa Floreani
Department of Surgical and Gastroenterological Sciences, University of Padova, Italy
Eur J Gastroenterol Hepatol 23:711-5. 2011..The efficacy of retreatment with pegylated interferon (PEG-IFN) plus ribavirin for patients relapsing after a previous treatment remains to be fully elucidated, although extended treatment seems to be the best option in such cases... - Female patients in fertile age with chronic hepatitis C, easy genotype, and persistently normal transaminases have a 100% chance to reach a sustained virological responseAnnarosa Floreani
Department of Surgical and Gastroenterological Sciences, University of Padova, Via Giustiniani, 2 35128 Padova, Italy
Eur J Gastroenterol Hepatol 23:997-1003. 2011..Patients with chronic hepatitis C and persistently normal alanine transaminase levels have recently been included in the guidelines for antiviral treatment... - Performance and utility of transient elastography and noninvasive markers of liver fibrosis in primary biliary cirrhosisAnnarosa Floreani
Department of Surgical and Gastroenterological Sciences, University of Padova, Padua, Italy
Dig Liver Dis 43:887-92. 2011..The performance of transient elastography in primary biliary cirrhosis has yet to be fully established... - Sex hormone profile and endometrial cancer risk in primary biliary cirrhosis: a case-control studyAnnarosa Floreani
Division of Gastroenterologia, Department of Surgical Sciences, University of Padova, Via Giustiniani 2, 35128, Padova, Italy
Eur J Obstet Gynecol Reprod Biol 103:154-7. 2002..To investigate the sex hormone profile and endometrial histology in primary biliary cirrhosis (PBC)... - A 35-year follow-up of a large cohort of patients with primary biliary cirrhosis seen at a single centreAnnarosa Floreani
Department of Surgical and Gastroenterological Sciences, University of Padova, Padova, Italy
Liver Int 31:361-8. 2011..The natural history of primary biliary cirrhosis (PBC) is still debated... - Prevalence of coeliac disease in primary biliary cirrhosis and of antimitochondrial antibodies in adult coeliac disease patients in ItalyA Floreani
Department of Surgical and Gastroenterological Sciences, University of Padova, Italy
Dig Liver Dis 34:258-61. 2002..Although an association between primary biliary cirrhosis and coeliac disease has recently been reported in Northern Europe, there are still conflicting data concerning this issue... - Performance of enhanced liver fibrosis plasma markers in asymptomatic individuals with ZZ α1-antitrypsin deficiencySabina Janciauskiene
Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany
Eur J Gastroenterol Hepatol 23:716-20. 2011..We hypothesized that the plasma markers for liver fibrosis, necrosis, and apoptosis may identify AATD individuals at higher risk for liver diseases... - Mass spectrometry measurement of plasma hepcidin for the prediction of iron overloadAnnarosa Floreani
Department of Surgical and Gastroenterological Sciences, University of Padova, Padova, Italy
Clin Chem Lab Med 49:197-206. 2011..The aims of the study were 1) to assess the performance of this method in different conditions of iron metabolism disorders; 2) to assess the diagnostic validity of non-invasive serum biomarkers in the identification of iron overload... - Lack of higher frequency of the chemokine receptor 5-delta32/delta32 genotype in hepatitis CAnna Maria Tommasi
Department of Surgical and Gastroenterological Sciences, University of Padova, Italy
J Clin Gastroenterol 40:440-3. 2006..The aim of the present study was to verify whether this mutation occurs in an Italian population with hepatitis C and whether it is an adverse host factor indicative of severity of liver disease and response to antiviral therapy... - Plasma adiponectin levels in primary biliary cirrhosis: a novel perspective for link between hypercholesterolemia and protection against atherosclerosisAnnarosa Floreani
Department of Surgical and Gastroenterological Sciences, University of Padova, Padova, Italy
Am J Gastroenterol 103:1959-65. 2008..High serum adiponectin levels appear to play a protective role in the development of either metabolic syndrome or cardiovascular disease... - Primary biliary cirrhosis and hepatitis C virus infectionAnnarosa Floreani
Department of Surgical and Gastroenterological Sciences, University of Padua, Via Giustiniani 2, 35128 Padua, Italy
Am J Gastroenterol 98:2757-62. 2003..44, p < 0.05). CONCLUSION: HCV-infected PBC patients are characterized by a biochemical profile with a modest rise in cholestatic enzymes but a high risk of developing HCC during follow-up... - Clinical course and outcome of autoimmune hepatitis/primary sclerosing cholangitis overlap syndromeAnnarosa Floreani
Department of Surgical and Gastroenterological Sciences, University of Padova, Padova, Italy
Am J Gastroenterol 100:1516-22. 2005..8117, p < 0.01) CONCLUSION: Patients with AIH/PSC overlap syndrome seem to benefit from immunosuppression + UDCA therapy, survival is apparently better than in "classical" PSC condition... - Endogenous interferon-alpha level is increased in hepatitis C virus (HCV)-positive pregnant womenDelia Maria Paternoster
Department of Gynecological Science and Human Reproduction, University of Padua, Padua, Italy
J Clin Gastroenterol 42:204-7. 2008..However, other cofactors influencing the vertical transmission are still debated... - Occupational risk of blood-borne viruses in healthcare workers: a 5-year surveillance programVincenzo Baldo
Department of Environmental Medicine and Public Health, Institute of Hygiene, University of Padua, Italy
Infect Control Hosp Epidemiol 23:325-7. 2002..7 [+/- 1.6] years), there was no increase in transaminases or seroconversions to any of the viral markers. CONCLUSION: Our accurate postexposure follow-up revealed a lack of transmission of HBV, HCV, and HIV... - Intra-hepatic cholestasis of pregnancy in hepatitis C virus infectionDelia M Paternoster
Department of Obstetrics, University of Padua, Italy
Acta Obstet Gynecol Scand 81:99-103. 2002.... - Epidemiological aspect of traumatic brain injury in Northeast ItalyVincenzo Baldo
Department of Environmental Medicine and Public Health, Institute of Hygiene, University of Padua, Padova, Italy
Eur J Epidemiol 18:1059-63. 2003..Traumatic brain injuries (TBIs) remain an important public health problem in developed countries. Hospital records were reviewed to ascertain the epidemiology of TBIs in Northeast Italy... - Circulating soluble-CD30 (sCD30) in patients with HCV-related chronic hepatitis and in patients with alcoholic liver diseaseFranca De Lazzari
Gastroenterology Unit, Department of Surgery and Gastroenterological Science, University of Padua, Via Giustiniani 2, 35128 Padova, Italy
Hepatogastroenterology 49:231-4. 2002..The aims were: 1) to evaluate sCD30 levels in patients with (a) alcoholic liver diseases and (b) HCV-related chronic hepatitis before and after interferon treatment; 2) to correlate sCD30 concentrations with IgE and IgA serum levels... 
Immunogenicity of three different influenza vaccines against homologous and heterologous strains in nursing home elderly residentsVincenzo Baldo
Department of Environmental Medicine and Public Health, Institute of Hygiene, University of Padua, Via Loredan 18, 35151 Padua, Italy
Clin Dev Immunol 2010:517198. 2010....- Liver disorders in the elderlyAnnarosa Floreani
Dept of Surgical and Gastroenterological Sciences, University of Padova, Via Giustiniani 2, Padua, Italy
Best Pract Res Clin Gastroenterol 23:909-17. 2009..The age of an end stage liver disease will increase over the next years, thus we will expects an increasing number of decompensated liver disease and hepatocellular carcinomas... - Response of influenza vaccines against heterovariant influenza virus strains in adults with chronic diseasesV Baldo
Department of Environmental Medicine and Public Health, Institute of Hygiene, University of Padua, Padua, Italy
J Clin Immunol 27:542-7. 2007.... - Relationship between apoptosis, tumour necrosis factor, and cell proliferation in chronic cholestasisA Floreani
Department of Surgical and Gastroenterological Sciences, University of Padua, Italy
Dig Liver Dis 33:570-5. 2001..Lymphocytic infiltration and apoptosis have both been suggested to mediate the destruction of hepatocytes and biliary epithelium in primary biliary cirrhosis... - HCV infection in haemodialysed patients: a role for serum IL-10 and TGF-beta1 in liver damage?P Burra
Gastroenterology Section, Department of Surgical and Gastroenterological Sciences, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
Dig Liver Dis 40:827-33. 2008..IL-10 and TGF-beta1 could play a role in this setting as, IL-10 down-regulates hepatic fibrosis, while TGF-beta1 is a pro-fibrotic cytokine... - Treatment of primary sclerosing cholangitis with low-dose ursodeoxycholic acid: results of a retrospective Italian multicentre surveyL Okolicsanyi
University of Parma, Parma, Italy
Dig Liver Dis 35:325-31. 2003..Ursodeoxycholic acid has been shown to be a useful agent, however the drug dosage and its effect on the clinical course are still under debate... - Cytokine, infiltrating macrophage and T cell-mediated response to development of primary and secondary human liver cancerM Bortolami
Department of Surgical and Gastroenterological Sciences, University of Padua, Italy
Dig Liver Dis 34:794-801. 2002.... - Bone metabolism and gonad function in male patients undergoing liver transplantation: a two-year longitudinal studyA Floreani
Department of Surgical and Gastroenterological Sciences, University of Padua, Italy
Osteoporos Int 12:749-54. 2001..Thus a high proportion of men with end-stage liver disease do have osteoporosis. After OLTx, an early recovery of gonad function is observed, followed by an increase in bone mass, which occurs from the sixth month onward... - Comparison of three different influenza vaccines in institutionalised elderlyV Baldo
Department of Environmental Medicine and Public Health, Institute of Hygiene, University of Padua, Via Loredan 18, 35151, Padua, Italy
Vaccine 19:3472-5. 2001..Our results suggest that immune response to influenza vaccination in institutionalised elderly is satisfactory... - MF59-adjuvanted influenza vaccine confers superior immunogenicity in adult subjects (18-60 years of age) with chronic diseases who are at risk of post-influenza complicationsV Baldo
Department of Environmental Medicine and Public Health, Institute of Hygiene, University of Padua, Padua, Italy
Vaccine 25:3955-61. 2007.... - Autosomal dominant benign recurrent intrahepatic cholestasis (BRIC) unlinked to 18q21 and 2q24A Floreani
Department of Surgical and Gastroenterological Sciences, University of Padova, Padova, Italy
Am J Med Genet 95:450-3. 2000..Segregation of haplotypes excluded the two regions in our family. These findings suggest further genetic heterogeneity of the origin of BRIC... - Plasma antioxidant levels in chronic cholestatic liver diseasesA Floreani
Department of Surgical and Gastroenterological Sciences, University of Padova, Italy
Aliment Pharmacol Ther 14:353-8. 2000..It has been suggested that oxygen-derived free radicals may be involved in the pathogenesis of chronic liver damage... - Chronic cholestasis associated with Turner's syndromeA Floreani
Department of Surgical and Gastroenterological Sciences, University of Padova, Italy
Digestion 60:587-9. 1999..A review of the few cases described in the literature and our own case reports support the hypothesis that liver disease in Turner's syndrome may have a variety of expressions including cholestasis... - Hepatic and extrahepatic malignancies in primary biliary cirrhosisA Floreani
Department of Surgical and Gastroenterological Sciences, University of Padova, Padova, Italy
Hepatology 29:1425-8. 1999..HCC has a relatively high prevalence in PBC and HCV superinfection may play an important part in favoring HCC. The incidence of breast cancer is not significantly higher in PBC than in the general population of the same area... - Sleep-Wake profiles in patients with primary biliary cirrhosisSara Montagnese
Department of Medicine, University of Padova, Padova, Italy
Liver Int 33:203-9. 2013..Impaired sleep quality and daytime sleepiness have been described in patients with primary biliary cirrhosis (PBC). However, no information is available on their sleep timing/diurnal preference... - Gastroduodenal and intestinal permeability in primary biliary cirrhosisVincenza Di Leo
Department of Surgical and Gastroenterological Sciences, University of Padova, Italy
Eur J Gastroenterol Hepatol 15:967-73. 2003..CONCLUSIONS: Gastrointestinal permeability is increased in PBC. Portal hypertension contributes to altered gastric mucosal permeability in non-PBC cirrhosis, whereas different epithelial dysfunction can be hypothesized in PBC... - Imaging of primary sclerosing cholangitis: preliminary results by two new non-invasive techniquesV Macchi
Section of Anatomy, Department of Human Anatomy and Physiology, University of Padova, Padua, Italy
Dig Liver Dis 36:614-21. 2004..Since computerised tomographic cholangiography offers additional information about biliary excretion, it may be proposed as an integrative technique in the diagnosis and follow-up of patients with primary sclerosing cholangitis... - Viral load in HCV RNA-positive pregnant womenD M Paternoster
Department of Obstetrics and Gynecology, Institute of Hygiene, University of Padua, Italy
Am J Gastroenterol 96:2751-4. 2001..Quantitative PCR testing is expensive and pointless. Any decision for elective cesarean section in HCV RNA+ mothers should be confirmed by other studies... - Epidemiology of HCV infectionV Baldo
Department of Environmental Medicine and Public Health, Institute of Hygiene, University of Padua, Padua, Italy
Curr Pharm Des 14:1646-54. 2008..4%). HCV prevention relies on identifying and counseling uninfected persons at risk of contracting hepatitis C... - Cytotoxic T-lymphocyte-associated antigen-4 single nucleotide polymorphisms and haplotypes in primary biliary cirrhosisPeter Donaldson
Centre for Liver Research, School of Clinical Medical Sciences, The Faculty of Medical Sciences, Newcastle University, Framlington Place, Newcastle upon Tyne, United Kingdom
Clin Gastroenterol Hepatol 5:755-60. 2007..However, there has been considerable debate over the validity of these associations and the precise location of the disease-promoting polymorphism... - HLA class II alleles, genotypes, haplotypes, and amino acids in primary biliary cirrhosis: a large-scale studyPeter T Donaldson
School of Clinical Medical Sciences Hepatology, Faculty of Medical Sciences, University of Newcastle, Newcastle upon Tyne, and Institute of Liver Studies, Kings College Hospital, London, UK
Hepatology 44:667-74. 2006..042, OR=0.65 in the UK patients; and 10% versus 31%, P=.00092, OR=0.25 in the Italian patients). In conclusion, a complex relationship exists between HLA and PBC, and some genetic associations may be population specific... - Are elderly patients poor candidates for pegylated interferon plus ribavirin in the treatment of chronic hepatitis C?Annarosa Floreani
J Am Geriatr Soc 54:549-50. 2006 - Alcohol is an important co-factor for both steatosis and fibrosis in Northern Italian patients with chronic hepatitis CPaolo Fabris
Department of Infectious Diseases and Tropical Medicine, S Bortolo Hospital, Viale Rodolfi 37, Vicenza, Italy
J Hepatol 41:644-51. 2004..To evaluate: (1) the relationship between steatosis and either host or viral factors; (2) the correlation between steatosis and fibrosis in patients with CHC... - Changing epidemiology of HCV and HBV infections in Northern Italy: a survey in the general populationPaolo Fabris
Department of Infectious Diseases and Tropical Medicine, S Bortolo Hospital, Vicenza, Italy
J Clin Gastroenterol 42:527-32. 2008.... - Mucosal IgA defect in primary biliary cirrhosisAnnarosa Floreani
Am J Gastroenterol 97:508-10. 2002 - Intrafamilial transmission of hepatitis C virus infectionEliseo Minola
Department of Infectious Diseases, Bergamo Hospital, Bergamo, Italy
Eur J Epidemiol 21:293-7. 2006..Sexual transmission may not be the main route of transmission though, since IVD use in the sexual partners themselves was independently associated with HCV infection... - Primary biliary cirrhosis: report of a focus study groupNora V Bergasa
State University of New York, Downstate Medical Center, Brooklyn, NY 11203, USA
Hepatology 40:1013-20. 2004 - Platelet count/spleen diameter ratio for the noninvasive diagnosis of esophageal varices: results of a multicenter, prospective, validation studyEdoardo G Giannini
Department of Internal Medicine, University of Genoa, Genoa, Italy
Am J Gastroenterol 101:2511-9. 2006..CONCLUSIONS: The platelet count/spleen diameter ratio may be proposed as a safe and reproducible means to improve the management of cirrhotic patients who should undergo screening endoscopy for EV... - Response to influenza vaccine in people with non-protective HI antibody titersVincenzo Baldo
Eur J Epidemiol 21:843-5. 2006..31; 95% CI: 1.37-3.89). The results suggest that antibody response to vaccine is satisfactory in elderly people previously lacking a protective antibody titer, and that the adjuvanted vaccine reveals a better immunogenicity...