P Fioretto

Summary

Affiliation: University of Padova
Country: Italy

Publications

  1. doi request reprint Reversal of diabetic nephropathy: lessons from pancreas transplantation
    Paola Fioretto
    Department of Medicine, University of Padova Medical School, Padova, Italy
    J Nephrol 25:13-8. 2012
  2. doi request reprint Effects of pancreas transplantation on the prevention and reversal of diabetic nephropathy
    Paola Fioretto
    Department of Medical and Surgical Sciences, University of Padova Medical School, Padova, Italy
    Contrib Nephrol 170:237-46. 2011
  3. pmc Tacrolimus and cyclosporine nephrotoxicity in native kidneys of pancreas transplant recipients
    Paola Fioretto
    Department of Medical and Surgical Sciences, University of Padova Medical School, Padova, Italy
    Clin J Am Soc Nephrol 6:101-6. 2011
  4. doi request reprint Residual microvascular risk in diabetes: unmet needs and future directions
    Paola Fioretto
    Department of Medical and Surgical Sciences, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Nat Rev Endocrinol 6:19-25. 2010
  5. doi request reprint The kidney in diabetes: dynamic pathways of injury and repair. The Camillo Golgi Lecture 2007
    P Fioretto
    Department of Medical and Surgical Sciences, University of Padua, Via Giustininiani n 2, 35128, Padua, Italy
    Diabetologia 51:1347-55. 2008
  6. ncbi request reprint Renal protection in diabetes: role of glycemic control
    Paola Fioretto
    Department of Medical and Surgical Sciences, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    J Am Soc Nephrol 17:S86-9. 2006
  7. ncbi request reprint Remodeling of renal interstitial and tubular lesions in pancreas transplant recipients
    P Fioretto
    Department of Medical and Surgical Sciences, University of Padua Medical School, Padua, Italy
    Kidney Int 69:907-12. 2006
  8. ncbi request reprint Antihypertensive treatment and multifactorial approach for renal protection in diabetes
    Paola Fioretto
    Department of Medical and Surgical Sciences, University of Padova Medical School, Padova, Italy
    J Am Soc Nephrol 16:S18-21. 2005
  9. ncbi request reprint Risk predictors in patients with diabetic nephropathy
    P Fioretto
    Department of Medical and Surgical Sciences, University of Padova Medical School, Via Giustiniani, n 2, Padova 35128, Italy
    Curr Diab Rep 1:245-50. 2001
  10. ncbi request reprint Patterns of renal injury in NIDDM patients with microalbuminuria
    P Fioretto
    Department of Internal Medicine, University of Padova Medical School, Italy
    Diabetologia 39:1569-76. 1996

Collaborators

Detail Information

Publications31

  1. doi request reprint Reversal of diabetic nephropathy: lessons from pancreas transplantation
    Paola Fioretto
    Department of Medicine, University of Padova Medical School, Padova, Italy
    J Nephrol 25:13-8. 2012
    ....
  2. doi request reprint Effects of pancreas transplantation on the prevention and reversal of diabetic nephropathy
    Paola Fioretto
    Department of Medical and Surgical Sciences, University of Padova Medical School, Padova, Italy
    Contrib Nephrol 170:237-46. 2011
    ..Thus, the lesions of DN are reversible by long-term normoglycemia, and that it is possible in humans associated with substantial architectural remodeling and healing of glomerular, tubular, and interstitial structures...
  3. pmc Tacrolimus and cyclosporine nephrotoxicity in native kidneys of pancreas transplant recipients
    Paola Fioretto
    Department of Medical and Surgical Sciences, University of Padova Medical School, Padova, Italy
    Clin J Am Soc Nephrol 6:101-6. 2011
    ....
  4. doi request reprint Residual microvascular risk in diabetes: unmet needs and future directions
    Paola Fioretto
    Department of Medical and Surgical Sciences, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Nat Rev Endocrinol 6:19-25. 2010
    ..In this Review, we highlight an urgent need to address the issue of microvascular residual risk in patients with or at risk of type 2 diabetes mellitus...
  5. doi request reprint The kidney in diabetes: dynamic pathways of injury and repair. The Camillo Golgi Lecture 2007
    P Fioretto
    Department of Medical and Surgical Sciences, University of Padua, Via Giustininiani n 2, 35128, Padua, Italy
    Diabetologia 51:1347-55. 2008
    ..Finally, the evidence and the possible significance of reversibility of diabetic renal lesions will be discussed, as well as future directions for research in this field...
  6. ncbi request reprint Renal protection in diabetes: role of glycemic control
    Paola Fioretto
    Department of Medical and Surgical Sciences, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    J Am Soc Nephrol 17:S86-9. 2006
    ..Therefore, a target of glycated hemoglobin levels <7% should be recommended in all patients with diabetes...
  7. ncbi request reprint Remodeling of renal interstitial and tubular lesions in pancreas transplant recipients
    P Fioretto
    Department of Medical and Surgical Sciences, University of Padua Medical School, Padua, Italy
    Kidney Int 69:907-12. 2006
    ..In contrast, there was no improvement in the arteriolar lesions. Whether this is due to long-term normoglycemia, reduction of CSA dose or other mechanisms is unclear...
  8. ncbi request reprint Antihypertensive treatment and multifactorial approach for renal protection in diabetes
    Paola Fioretto
    Department of Medical and Surgical Sciences, University of Padova Medical School, Padova, Italy
    J Am Soc Nephrol 16:S18-21. 2005
    ..In conclusion, a target-driven, long-term, intensified intervention aimed at multiple risk factors should be recommended in patients with diabetes to preserve their kidney function...
  9. ncbi request reprint Risk predictors in patients with diabetic nephropathy
    P Fioretto
    Department of Medical and Surgical Sciences, University of Padova Medical School, Via Giustiniani, n 2, Padova 35128, Italy
    Curr Diab Rep 1:245-50. 2001
    ..To date the best available predictor of overt nephropathy is microalbuminuria. In this article we review the validity of microalbuminuria as a predictor of overt nephropathy and consider other markers of nephropathy risk...
  10. ncbi request reprint Patterns of renal injury in NIDDM patients with microalbuminuria
    P Fioretto
    Department of Internal Medicine, University of Padova Medical School, Italy
    Diabetologia 39:1569-76. 1996
    ....
  11. ncbi request reprint Acute-phase markers of inflammation and glomerular structure in patients with type 2 diabetes
    Michele Dalla Vestra
    Department of Medical and Surgical Sciences, University of Padova Medical School, Padova, Italy
    J Am Soc Nephrol 16:S78-82. 2005
    ..25 P < 0.05). In conclusion, this study demonstrates that acute-phase markers of inflammation are associated with nephropathy status and GBM thickening, suggesting a role for inflammation in the pathogenesis of diabetic glomerulopathy...
  12. ncbi request reprint Role of mesangial expansion in the pathogenesis of diabetic nephropathy
    M Dalla Vestra
    Department of Medical and Surgical Sciences, University of Padua, Italy
    J Nephrol 14:S51-7. 2001
    ..This is a new concept in nephrology, and the understanding of the mechanisms involved in the glomerular architectural remodelling might have important clinical and therapeutic implications...
  13. ncbi request reprint Down-regulation of glomerular matrix metalloproteinase-2 gene in human NIDDM
    D Del Prete
    Institute of Internal Medicine, University of Padova, Italy
    Diabetologia 40:1449-54. 1997
    ..MMP2 gene down-regulation seems to be a molecular epiphenomenon of diabetes, rather than a marker of diabetic nephropathy...
  14. ncbi request reprint Is podocyte injury relevant in diabetic nephropathy? Studies in patients with type 2 diabetes
    Michele Dalla Vestra
    Department of Medical and Surgical Sciences, University of Padova Medical School, Padova, Italy
    Diabetes 52:1031-5. 2003
    ..These findings also suggest that in white type 2 diabetic patients, the density of podocytes may be functionally more relevant than the absolute number...
  15. ncbi request reprint Effect of lercanidipine compared with ramipril on albumin excretion rate in hypertensive Type 2 diabetic patients with microalbuminuria: DIAL study (diabete, ipertensione, albuminuria, lercanidipina)
    M Dalla Vestra
    Dipartimento di Scienze Mediche e Chirurgiche, Clinica Medica I, Universita di Padova, Italy
    Diabetes Nutr Metab 17:259-66. 2004
    ..Indeed, both lercanidipine and ramipril treatments resulted in a significant reduction in AER without a statistically significant difference between the two groups...
  16. pmc Histopathology of diabetic nephropathy
    Paola Fioretto
    Department of Medical and Surgical Sciences, University of Padova Medical School, Via Giustiniana 2, 35128 Padua, Italy
    Semin Nephrol 27:195-207. 2007
    ..Finally, evidence is presented that the reversal of established lesions of diabetic nephropathy is possible...
  17. ncbi request reprint Nitric oxide modulation of renal and cardiac hemodynamics in type 2 diabetes
    Michele Dalla Vestra
    Department of Medical and Surgical Sciences, Clinica Medica I, University of Padova, Via Giustiniani 2, 35128, Italy
    Eur J Endocrinol 146:687-94. 2002
    ..To evaluate endothelial function in type 2 diabetic patients with and without diabetic nephropathy...
  18. doi request reprint Bariatric surgery improves atherogenic LDL profile by triglyceride reduction
    Sabina Zambon
    Department of Medical and Surgical Sciences, University of Padova, Via Giustiniani, 2, 35128 Padova, Italy
    Obes Surg 19:190-5. 2009
    ..Objective of this study was to determine the relations between plasma phospholipid fatty acid composition and the presence of small dense LDL particles in morbidly obese patients treated with laparoscopic gastric banding (LAGB)...
  19. ncbi request reprint Quantitave and qualitative changes in vascular endothelial growth factor gene expression in glomeruli of patients with type 2 diabetes
    Elena Bortoloso
    Department of Medical and Surgical Sciences, Division of Nephrology, Laboratory of Molecular Biology, University of Padua, Padua, Italy
    Eur J Endocrinol 150:799-807. 2004
    ..VEGF plays an important role in the pathogenesis of diabetic retinopathy. This study examined the relationship between VEGF and its isoforms and the severity of diabetic nephropathy in type 2 diabetes...
  20. ncbi request reprint Effects of angiotensin converting enzyme inhibitors and calcium antagonists on atrial natriuretic peptide release and action and on albumin excretion rate in hypertensive insulin-dependent diabetic patients
    P Fioretto
    Istituto di Medicina Interna, Policlinico Universitario, Padova, Italy
    Am J Hypertens 5:837-46. 1992
    ....
  21. ncbi request reprint Effects of cigarette smoking on glomerular structure and function in type 2 diabetic patients
    Bruno Baggio
    Department of Medical and Surgical Sciences, University Hospital, Padua, Italy
    J Am Soc Nephrol 13:2730-6. 2002
    ..In conclusion, cigarette smoking affects glomerular structure and function in type 2 diabetes and may be an important factor for the onset and progression of diabetic nephropathy...
  22. ncbi request reprint Na/H and Li/Na exchange in red blood cells of normotensive and hypertensive patients with insulin dependent diabetes mellitus (IDDM)
    A Semplicini
    Institutes of Medicina Clinica and Medicina Interna, University of Padova, Italy
    Am J Hypertens 2:174-7. 1989
    ..21, n = 29). In conclusion this work confirms that Na/H and Li/Na CTT are function modes of the same transporter and that an increased activity of Na/H CTT might play a role in the blood pressure increase in IDDM...
  23. ncbi request reprint Cystatin C is a more sensitive marker than creatinine for the estimation of GFR in type 2 diabetic patients
    Michele Mussap
    Department of Laboratory Medicine, University of Padova, Padova, Italy
    Kidney Int 61:1453-61. 2002
    ..This study was designed to test whether serum cystatin C can replace serum creatinine for the early assessment of nephropathy in patients with type 2 diabetes...
  24. ncbi request reprint Arterial stiffness and cognition in elderly persons with impaired glucose tolerance and microalbuminuria
    Angela M Abbatecola
    Department of Geriatric Medicine and Metabolic Diseases, Second University of Naples, Italy, Piazza Miraglia 2, I 80138 Naples, Italy
    J Gerontol A Biol Sci Med Sci 63:991-6. 2008
    ....
  25. ncbi request reprint The angiotensin-converting enzyme DD genotype is associated with glomerulopathy lesions in type 2 diabetes
    Anna Solini
    Department of Internal Medicine, University of Ferrara Medical School, Ferrara, Italy
    Diabetes 51:251-5. 2002
    ..In conclusion, the ACE DD genotype is associated with diabetic glomerulopathy lesions, making the study of this polymorphism helpful in identifying those type 2 diabetic patients at higher risk of fast DN progression...
  26. ncbi request reprint Preventing microalbuminuria in type 2 diabetes
    Michael Mauer
    N Engl J Med 352:833-4; author reply 833-4. 2005
  27. ncbi request reprint Enhancing the predictive value of urinary albumin for diabetic nephropathy
    M Luiza Caramori
    Department of Medicine, University of Minnesota, Minneapolis, Minnesota 55455, USA
    J Am Soc Nephrol 17:339-52. 2006
    ..Thus, although further research in DN biomarkers and predictors is greatly needed, a careful integrated evaluation of currently available parameters can improve our ability to predict DN risk in individual patients...
  28. ncbi request reprint PC-1 amino acid variant Q121 is associated with a lower glomerular filtration rate in type 2 diabetic patients with abnormal albumin excretion rates
    Salvatore De Cosmo
    Unit of Endocrinology, Scientific Institute Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy
    Diabetes Care 26:2898-902. 2003
    ..To study the relationships between the PC-1 K121Q variant and diabetic nephropathy (DN) in patients with type 2 diabetes...
  29. ncbi request reprint Low glomerular filtration rate in normoalbuminuric type 1 diabetic patients: an indicator of more advanced glomerular lesions
    M Luiza Caramori
    Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA
    Diabetes 52:1036-40. 2003
    ..For these reasons, we suggest that regular measurements of GFR be performed in long-standing normoalbuminuric type 1 diabetic female diabetic patients, especially in those with retinopathy or hypertension...
  30. ncbi request reprint Insulin resistance and the cluster of abnormalities related to the metabolic syndrome are associated with reduced glomerular filtration rate in patients with type 2 diabetes
    Salvatore De Cosmo
    Unit of Endocrinology, Scientific Institute Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy
    Diabetes Care 29:432-4. 2006
  31. ncbi request reprint Cellular basis of diabetic nephropathy: IV. Antioxidant enzyme mRNA expression levels in skin fibroblasts of type 1 diabetic sibling pairs
    Maria Luiza Caramori
    Department of Pediatrics, University of Minnesota, M D 420 Delaware Street S E, Mayo Mail Code 491, Minneapolis, MN 55455, USA
    Nephrol Dial Transplant 21:3122-6. 2006
    ..Blunted cultured skin fibroblast (SF) antioxidant enzyme responses to hyperglycaemia are associated with diabetic nephropathy risk. The present study explores whether this association is, at least in part, genetically determined...