Manuela Ferracin

Summary

Affiliation: University of Ferrara
Country: Italy

Publications

  1. pmc miR-125b targets erythropoietin and its receptor and their expression correlates with metastatic potential and ERBB2/HER2 expression
    Manuela Ferracin
    Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy
    Mol Cancer 12:130. 2013
  2. doi request reprint MicroRNAs: toward the clinic for breast cancer patients
    Manuela Ferracin
    Department of Experimental and Diagnostic Medicine, University of Ferrara, Ferrara, Italy
    Semin Oncol 38:764-75. 2011
  3. doi request reprint Micromarkers: miRNAs in cancer diagnosis and prognosis
    Manuela Ferracin
    Dipartimento di Medicina Sperimentale e Diagnostica, Universita di Ferrara, Via Luigi Borsari 46, Ferrara, Italy
    Expert Rev Mol Diagn 10:297-308. 2010
  4. pmc MicroRNA profiling for the identification of cancers with unknown primary tissue-of-origin
    Manuela Ferracin
    Dipartimento di Medicina Sperimentale e Diagnostica, Universita di Ferrara, Ferrara, Italy
    J Pathol 225:43-53. 2011
  5. pmc MicroRNAs involvement in fludarabine refractory chronic lymphocytic leukemia
    Manuela Ferracin
    Dipartimento di Medicina Sperimentale e Diagnostica Università di Ferrara, Ferrara, Italy
    Mol Cancer 9:123. 2010
  6. pmc mRNA/microRNA gene expression profile in microsatellite unstable colorectal cancer
    Giovanni Lanza
    Department of Experimental and Diagnostic Medicine and Interdepartment Center for Cancer Research, University of Ferrara, Ferrara, Italy
    Mol Cancer 6:54. 2007
  7. ncbi request reprint Absolute quantification of cell-free microRNAs in cancer patients
    Manuela Ferracin
    Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy
    Oncotarget 6:14545-55. 2015
  8. doi request reprint Liver tumorigenicity promoted by microRNA-221 in a mouse transgenic model
    Elisa Callegari
    Dipartimento di Medicina Sperimentale e Diagnostica, Universita di Ferrara, Ferrara, Italy
    Hepatology 56:1025-33. 2012
  9. ncbi request reprint Identification of differentially expressed microRNAs by microarray: a possible role for microRNA genes in pituitary adenomas
    Arianna Bottoni
    Department of Biomedical Sciences and Advanced Therapies, Section of Endocrinology, University of Ferrara, Ferrara, Italy
    J Cell Physiol 210:370-7. 2007
  10. doi request reprint MicroRNAs dysregulation in human malignant pleural mesothelioma
    Veronica Balatti
    Department of Morphology and Embryology, Section of Cellular Biology and Molecular Genetics, and Center of Biotechnology, University of Ferrara, Ferrara, Italy
    J Thorac Oncol 6:844-51. 2011

Collaborators

Detail Information

Publications21

  1. pmc miR-125b targets erythropoietin and its receptor and their expression correlates with metastatic potential and ERBB2/HER2 expression
    Manuela Ferracin
    Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy
    Mol Cancer 12:130. 2013
    ..Here, we investigated its targets in breast cancer cell lines after miRNA-mimic transfection. We examined the interactions of the validated targets with ERBB2 oncogene and the correlation of miR-125b expression with clinical variables...
  2. doi request reprint MicroRNAs: toward the clinic for breast cancer patients
    Manuela Ferracin
    Department of Experimental and Diagnostic Medicine, University of Ferrara, Ferrara, Italy
    Semin Oncol 38:764-75. 2011
    ..In this review, we describe current knowledge of the role of microRNAs in breast cancer...
  3. doi request reprint Micromarkers: miRNAs in cancer diagnosis and prognosis
    Manuela Ferracin
    Dipartimento di Medicina Sperimentale e Diagnostica, Universita di Ferrara, Via Luigi Borsari 46, Ferrara, Italy
    Expert Rev Mol Diagn 10:297-308. 2010
    ..In addition, circulating miRNAs are expected to provide improved specificity and/or sensitivity over presently available markers...
  4. pmc MicroRNA profiling for the identification of cancers with unknown primary tissue-of-origin
    Manuela Ferracin
    Dipartimento di Medicina Sperimentale e Diagnostica, Universita di Ferrara, Ferrara, Italy
    J Pathol 225:43-53. 2011
    ....
  5. pmc MicroRNAs involvement in fludarabine refractory chronic lymphocytic leukemia
    Manuela Ferracin
    Dipartimento di Medicina Sperimentale e Diagnostica Università di Ferrara, Ferrara, Italy
    Mol Cancer 9:123. 2010
    ....
  6. pmc mRNA/microRNA gene expression profile in microsatellite unstable colorectal cancer
    Giovanni Lanza
    Department of Experimental and Diagnostic Medicine and Interdepartment Center for Cancer Research, University of Ferrara, Ferrara, Italy
    Mol Cancer 6:54. 2007
    ..Colorectal cancer develops through two main genetic instability pathways characterized by distinct pathologic features and clinical outcome...
  7. ncbi request reprint Absolute quantification of cell-free microRNAs in cancer patients
    Manuela Ferracin
    Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy
    Oncotarget 6:14545-55. 2015
    ..66 and 0.73 respectively. This study finally powers the use of cell-free miRNAs as cancer biomarkers and propose miR-181a-5p as a diagnostic breast cancer biomarker. ..
  8. doi request reprint Liver tumorigenicity promoted by microRNA-221 in a mouse transgenic model
    Elisa Callegari
    Dipartimento di Medicina Sperimentale e Diagnostica, Universita di Ferrara, Ferrara, Italy
    Hepatology 56:1025-33. 2012
    ..To validate the tumor-promoting effect of miR-221, we showed that in vivo delivery of anti-miR-221 oligonucleotides leads to a significant reduction of the number and size of tumor nodules...
  9. ncbi request reprint Identification of differentially expressed microRNAs by microarray: a possible role for microRNA genes in pituitary adenomas
    Arianna Bottoni
    Department of Biomedical Sciences and Advanced Therapies, Section of Endocrinology, University of Ferrara, Ferrara, Italy
    J Cell Physiol 210:370-7. 2007
    ..Predictive miRNAs could be potentially useful diagnostic markers, improving the classification of pituitary adenomas...
  10. doi request reprint MicroRNAs dysregulation in human malignant pleural mesothelioma
    Veronica Balatti
    Department of Morphology and Embryology, Section of Cellular Biology and Molecular Genetics, and Center of Biotechnology, University of Ferrara, Ferrara, Italy
    J Thorac Oncol 6:844-51. 2011
    ..Recent studies have shown the differential expression of mature miRNAs in several human cancers, suggesting their potential role as oncogenes or tumor suppressor genes...
  11. ncbi request reprint MicroRNAs in human cancer: from research to therapy
    Massimo Negrini
    Dipartimento di Medicina Sperimentale e Diagnostica, Centro Interdipartimentale per la Ricerca sul Cancro, Universita di Ferrara, Via Luigi Borsari 46, 44100 Ferrara, Italy
    J Cell Sci 120:1833-40. 2007
    ..Finally, miRNAs can be used as diagnostic markers, and their potential as therapeutic molecules has moved miRNAs from the area of basic research to the field of cancer biotechnology...
  12. doi request reprint Quantification of circulating miRNAs by droplet digital PCR: comparison of EvaGreen- and TaqMan-based chemistries
    Elena Miotto
    Department of Morphology, Surgery, and Experimental Medicine, Pathology Oncology and Experimental Biology Section, University of Ferrara, Ferrara, Italy
    Cancer Epidemiol Biomarkers Prev 23:2638-42. 2014
    ..See all the articles in this CEBP Focus section, "Biomarkers, Biospecimens, and New Technologies in Molecular Epidemiology."..
  13. doi request reprint Gene expression changes in progression of cervical neoplasia revealed by microarray analysis of cervical neoplastic keratinocytes
    John Charles Rotondo
    Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Via Fossato di Mortara 64 b, Ferrara, Italy
    J Cell Physiol 230:806-12. 2015
    ..Phosphoglycerate dehydrogenase is likely to be associated with tumorigenesis and may be a potential prognostic marker for CIN progression...
  14. doi request reprint Clinical monoclonal B lymphocytosis versus Rai 0 chronic lymphocytic leukemia: A comparison of cellular, cytogenetic, molecular, and clinical features
    Fortunato Morabito
    Authors Affiliations Department of Onco Hematology, A O of Cosenza, Cosenza Department of Clinical Sciences and Community Health, University of Milano and Hematology 1 CTMO, Foundation IRCCS Ca Granda Ospedale Maggiore Policlinico, Milano SS Molecular Diagnostics, Scientific Direction, and Direzione Scientifica, IRCCS, San Martino IST, Genoa Department of Experimental and Diagnostic Medicine, University of Ferrara, Ferrara Division of Hematology, A O Arcispedale Santa Maria Nuova IRCCS, Reggio Emilia Division of Hematology, University of Messina, Messina Department of Oncology and Hematology, Pugliese Ciaccio Hospital University of Magna Graecia and Cancer Center, Catanzaro Division of Hematology, Department of Biomedical Sciences, University of Catania and Ferrarotto Hospital, Catania and Division of Hematology, Department of Clinical and Experimental Medicine, Amedeo Avogadro University of Eastern Piedmont, Novara, Italy
    Clin Cancer Res 19:5890-900. 2013
    ....
  15. pmc Oncogenic role of miR-483-3p at the IGF2/483 locus
    Angelo Veronese
    Dipartimento di Medicina Sperimentale e Diagnostica, Universita di Ferrara, Ferrara, Italy
    Cancer Res 70:3140-9. 2010
    ..Our results indicate that miR-483-3p could function as an antiapoptotic oncogene in various human cancers and reveal a new, potentially important target for anticancer therapy...
  16. doi request reprint Altered miRNA expression in T regulatory cells in course of multiple sclerosis
    Giuseppe De Santis
    Section of Neurology, Department of Medical and Surgical Sciences of the Communication and Behaviour, University of Ferrara, Ferrara, Italy
    J Neuroimmunol 226:165-71. 2010
    ..Recently, microRNAs (miRNAs) have been involved in autoimmune disorders and their loss-of-function in immune cells was shown to facilitate systemic autoimmune disorders. Here, we analyzed the miRNA expression profile in Tregs from MS-RR...
  17. doi request reprint MicroRNA profiles in hippocampal granule cells and plasma of rats with pilocarpine-induced epilepsy--comparison with human epileptic samples
    Paolo Roncon
    Department of Medical Sciences, Section of Pharmacology and Neuroscience Center, University of Ferrara, Italy
    Sci Rep 5:14143. 2015
    ..Two main clusters were identified that segregated controls from all other groups. Those miRNAs that are altered in plasma before the first spontaneous seizure, like miR-9a-3p, may be proposed as putative biomarkers of epileptogenesis. ..
  18. pmc Genetic subclonal complexity and miR125a-5p down-regulation identify a subset of patients with inferior outcome in low-risk CLL patients
    Gian Matteo Rigolin
    Hematology Section, Department of Medical Sciences, University of Ferrara, University Hospital Arcispedale S Anna, Ferrara, Italy
    Oncotarget 5:140-9. 2014
    ....
  19. doi request reprint Micromarkers 2.0: an update on the role of microRNAs in cancer diagnosis and prognosis
    Manuela Ferracin
    a Department of Morphology, Surgery and Experimental Medicine and Laboratory for Technologies of Advanced Therapies LTTA, University of Ferrara, Ferrara, Italy
    Expert Rev Mol Diagn 15:1369-81. 2015
    ..This review presents an update on cancer diagnostic and prognostic microRNAs, discusses novel tools for prognostic microRNAs identification and evaluates the possible translation of these discoveries to the clinic. ..
  20. pmc Identification of miRNAs differentially expressed in human epilepsy with or without granule cell pathology
    Silvia Zucchini
    Department of Medical Sciences, Section of Pharmacology and Neuroscience Center, University of Ferrara, Ferrara, Italy National Institute of Neuroscience, Torino, Italy Laboratory for Technologies of Advanced Therapies LTTA, University of Ferrara, Ferrara, Italy
    PLoS ONE 9:e105521. 2014
    ..Thus, miR487a could be the first identified element of a miRNA signature that may be useful for prognostic evaluation of post-surgical epilepsy and may drive mechanistic studies leading to the identification of therapeutic targets. ..
  21. pmc Increase of microRNA-210, decrease of raptor gene expression and alteration of mammalian target of rapamycin regulated proteins following mithramycin treatment of human erythroid cells
    Nicoletta Bianchi
    Department of Life Sciences and Biotechnology, Ferrara University, Ferrara, Italy
    PLoS ONE 10:e0121567. 2015
    ..In conclusion, microRNA-210 and raptor are involved in mithramycin-mediated erythroid differentiation of K562 cells and participate to the fine-tuning and control of γ-globin gene expression in erythroid precursor cells. ..