Diego Ferone

Summary

Affiliation: University of Genoa
Country: Italy

Publications

  1. ncbi request reprint Sympathovagal imbalance in acromegalic patients
    Eugenia Resmini
    Department of Endocrinology and Metabolism, Center of Excellence for Biomedical Research, University of Genova, Genova, Italy
    J Clin Endocrinol Metab 91:115-20. 2006
  2. doi request reprint Italian Society of Endocrinology Career Award Lecture: from somatostatin to…somatomedin
    D Ferone
    Endocrinology Unit, Department of Internal Medicine and Medical Specialties and Center of Excellence for Biomedical Research, IRCCS AOU San Martino IST, University of Genoa, Italy
    J Endocrinol Invest 35:869-74. 2012
  3. doi request reprint Immunohistochemical localization and quantitative expression of somatostatin receptors in normal human spleen and thymus: Implications for the in vivo visualization during somatostatin receptor scintigraphy
    D Ferone
    Department of Endocrinological and Medical Sciences and Center of Excellence for Biomedical Research, University of Genoa, Viale Benedetto XV, 6 16132 Genoa, Italy
    J Endocrinol Invest 35:528-34. 2012
  4. doi request reprint Correlation of in vitro and in vivo somatotropic adenoma responsiveness to somatostatin analogs and dopamine agonists with immunohistochemical evaluation of somatostatin and dopamine receptors and electron microscopy
    Diego Ferone
    Department of Internal Medicine, Erasmus Medical Center, 3015 GE Rotterdam, The Netherlands
    J Clin Endocrinol Metab 93:1412-7. 2008
  5. ncbi request reprint Treatment of a pituitary metastasis from a neuroendocrine tumour: case report and literature review
    Umberto Goglia
    Department of Endocrinological and Medical Sciences and Center of Excellence for Biomedical Research, University of Genova, Viale Benedetto XV, 6, Genova 16132, Italy
    Pituitary 11:93-102. 2008
  6. ncbi request reprint Preclinical and clinical experiences with the role of dopamine receptors in the treatment of pituitary adenomas
    Diego Ferone
    Department of Endocrinological and Medical Sciences and Center of Excellence for Biomedical Research, University of Genova, Genova, Italy
    Eur J Endocrinol 156:S37-43. 2007
  7. doi request reprint The clinical-molecular interface of somatostatin, dopamine and their receptors in pituitary pathophysiology
    Diego Ferone
    Department of Endocrinological and Medical Sciences and Center of Excellence for Biomedical Research, University of Genova, Italy
    J Mol Endocrinol 42:361-70. 2009
  8. ncbi request reprint Neuroendocrine-immune interactions: the role of cortistatin/somatostatin system
    Diego Ferone
    Department of Endocrinological and Metabolic Sciences, University of Genova, Viale Benedetto XV, 6, 16132 Genova, Italy
    Ann N Y Acad Sci 1069:129-44. 2006
  9. ncbi request reprint Potential indications for somatostatin analogues: immune system and limphoproliferative disorders
    D Ferone
    Department of Endocrinological and Metabolic Sciences, University of Genova, Italy
    J Endocrinol Invest 28:111-7. 2005
  10. ncbi request reprint Initial staging of lymphoma with octreotide and other receptor imaging agents
    Diego Ferone
    Department of Endocrinological and Metabolic Sciences, University of Genoa, Viale Benedetto XV 6, 16132 Genoa, Italy
    Semin Nucl Med 35:176-85. 2005

Collaborators

Detail Information

Publications70

  1. ncbi request reprint Sympathovagal imbalance in acromegalic patients
    Eugenia Resmini
    Department of Endocrinology and Metabolism, Center of Excellence for Biomedical Research, University of Genova, Genova, Italy
    J Clin Endocrinol Metab 91:115-20. 2006
    ..Sympathovagal imbalance is a common finding in diabetes and is considered to be a cardiovascular risk factor. No data are available on sympathovagal balance (SB) in acromegalic patients...
  2. doi request reprint Italian Society of Endocrinology Career Award Lecture: from somatostatin to…somatomedin
    D Ferone
    Endocrinology Unit, Department of Internal Medicine and Medical Specialties and Center of Excellence for Biomedical Research, IRCCS AOU San Martino IST, University of Genoa, Italy
    J Endocrinol Invest 35:869-74. 2012
    ..Furthermore, functional consequences of such an interaction in modulation of signaling pathways linked to pathological conditions specifically in cancer are discussed...
  3. doi request reprint Immunohistochemical localization and quantitative expression of somatostatin receptors in normal human spleen and thymus: Implications for the in vivo visualization during somatostatin receptor scintigraphy
    D Ferone
    Department of Endocrinological and Medical Sciences and Center of Excellence for Biomedical Research, University of Genoa, Viale Benedetto XV, 6 16132 Genoa, Italy
    J Endocrinol Invest 35:528-34. 2012
    ..While the spleen is clearly visualized, the thymus is not depicted, although both contain SSR...
  4. doi request reprint Correlation of in vitro and in vivo somatotropic adenoma responsiveness to somatostatin analogs and dopamine agonists with immunohistochemical evaluation of somatostatin and dopamine receptors and electron microscopy
    Diego Ferone
    Department of Internal Medicine, Erasmus Medical Center, 3015 GE Rotterdam, The Netherlands
    J Clin Endocrinol Metab 93:1412-7. 2008
    ..In nine cases, GH and PRL content was further studied by immunoelectron microscopy...
  5. ncbi request reprint Treatment of a pituitary metastasis from a neuroendocrine tumour: case report and literature review
    Umberto Goglia
    Department of Endocrinological and Medical Sciences and Center of Excellence for Biomedical Research, University of Genova, Viale Benedetto XV, 6, Genova 16132, Italy
    Pituitary 11:93-102. 2008
    ..To our knowledge, this is the first case of combined treatment using "cold" and radiolabelled octreotide in a pituitary metastasis from a neuroendocrine tumour...
  6. ncbi request reprint Preclinical and clinical experiences with the role of dopamine receptors in the treatment of pituitary adenomas
    Diego Ferone
    Department of Endocrinological and Medical Sciences and Center of Excellence for Biomedical Research, University of Genova, Genova, Italy
    Eur J Endocrinol 156:S37-43. 2007
    ....
  7. doi request reprint The clinical-molecular interface of somatostatin, dopamine and their receptors in pituitary pathophysiology
    Diego Ferone
    Department of Endocrinological and Medical Sciences and Center of Excellence for Biomedical Research, University of Genova, Italy
    J Mol Endocrinol 42:361-70. 2009
    ....
  8. ncbi request reprint Neuroendocrine-immune interactions: the role of cortistatin/somatostatin system
    Diego Ferone
    Department of Endocrinological and Metabolic Sciences, University of Genova, Viale Benedetto XV, 6, 16132 Genova, Italy
    Ann N Y Acad Sci 1069:129-44. 2006
    ..However, CST has also properties distinct from SS, and the higher expression of CST in immune cells supports the hypothesis that CST rather than SS may act as a potential endogenous ligand for SSRs in the human immune system...
  9. ncbi request reprint Potential indications for somatostatin analogues: immune system and limphoproliferative disorders
    D Ferone
    Department of Endocrinological and Metabolic Sciences, University of Genova, Italy
    J Endocrinol Invest 28:111-7. 2005
    ....
  10. ncbi request reprint Initial staging of lymphoma with octreotide and other receptor imaging agents
    Diego Ferone
    Department of Endocrinological and Metabolic Sciences, University of Genoa, Viale Benedetto XV 6, 16132 Genoa, Italy
    Semin Nucl Med 35:176-85. 2005
    ..Recent findings emerging from in vitro studies on somatostatin receptor physiology in immune cells will certainly reopen and expand the potential applications of somatostatin analogs for in vivo diagnostic and therapeutic options...
  11. ncbi request reprint Somatostatin and dopamine receptor expression in lung carcinoma cells and effects of chimeric somatostatin-dopamine molecules on cell proliferation
    Diego Ferone
    Dept of Endocrinological and Metabolic Sciences, University of Genoa, Viale Benedetto XV 6, 16132 Genoa, Italy
    Am J Physiol Endocrinol Metab 289:E1044-50. 2005
    ..The Calu-6 cell line, constitutively expressing SSR and DR, provides a suitable model to elucidate the mechanism of action of SSA and DA on regulation of cell growth and to characterize the interaction between SSR and DR...
  12. ncbi request reprint Novel chimeric somatostatin analogs: facts and perspectives
    Diego Ferone
    Department of Endocrinological and Medical Sciences DiSEM and Center of Excellence for Biomedical Research, University of Genova, Viale Benedetto XV, 6, 16132 Genova, Italy
    Eur J Endocrinol 156:S23-8. 2007
    ..However, these recent observations form the basis for the application of new interesting strategies for the treatment of not only pituitary tumors but also other human malignancies...
  13. ncbi request reprint The role of somatostatin analogs in the management of immunoproliferative disease
    D Ferone
    Department of Endocrinological and Metabolic Sciences, University of Genova, Italy
    J Endocrinol Invest 26:103-8. 2003
  14. ncbi request reprint Somatostatin receptor distribution and function in immune system
    D Ferone
    Department of Endocrinological and Metabolic Sciences Di S E M, University of Genova, Viale Benedetto XV 6, Genoa 16132, Italy
    Dig Liver Dis 36:S68-77. 2004
    ..We also discuss the wide distribution of somatostatin and its specific five receptor subtypes in immune cell lines, as well as throughout animal and human lymphoid organs, in both normal and pathological conditions...
  15. ncbi request reprint Quantitative and functional expression of somatostatin receptor subtypes in human thymocytes
    Diego Ferone
    Department of Internal Medicine, Erasmus Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands
    Am J Physiol Endocrinol Metab 283:E1056-66. 2002
    ....
  16. ncbi request reprint Current diagnostic guidelines for biochemical diagnosis of acromegaly
    D Ferone
    Department of Endocrinological and Metabolic Sciences DiSEM, University of Genoa, Genoa, Italy
    Minerva Endocrinol 29:207-23. 2004
    ..The present review discuss principally the biochemical diagnosis of acromegaly based on these articles and on the experience collected in an endocrinological unit considered as reference center for pituitary diseases...
  17. ncbi request reprint Rapid pituitary tumor shrinkage with dissociation between antiproliferative and antisecretory effects of a long-acting octreotide in an acromegalic patient
    Eugenia Resmini
    Department of Endocrinology and Metabolism, University of Genova, Viale Benedetto XV 6, 16132 Genoa, Italy
    J Clin Endocrinol Metab 92:1592-9. 2007
    ..However, the mechanisms of action of SSAs in inhibiting tumor growth and hormonal secretion are only partially understood, and the two effects may occur independently...
  18. doi request reprint Balance between somatostatin and D2 receptor expression drives TSH-secreting adenoma response to somatostatin analogues and dopastatins
    Federico Gatto
    Department of Internal Medicine and Center of Excellence for Biomedical Research, University of Genoa, Viale Benedetto XV 2, Genoa, Italy
    Clin Endocrinol (Oxf) 76:407-14. 2012
    ..Clinically available sst(2) -preferring analogues, octreotide and lanreotide, induce normalization of hormone levels in approximately 90% of patients and tumour shrinkage in 45%...
  19. ncbi request reprint Dopamine receptor expression and function in corticotroph ectopic tumors
    Rosario Pivonello
    Department of Internal Medicine, Erasmus Medical Center, 3015 GE Rotterdam, The Netherlands
    J Clin Endocrinol Metab 92:65-9. 2007
    ..Dopamine receptor (DR) expression and dopamine agonist (DA) effectiveness have never been demonstrated in neuroendocrine tumors associated with ectopic ACTH syndrome (EAS)...
  20. doi request reprint Role of dopamine receptors in normal and tumoral pituitary corticotropic cells and adrenal cells
    Mara Boschetti
    Department of Endocrinology and Medical Sciences, University of Genova, Genova, Italy
    Neuroendocrinology 92:17-22. 2010
    ..Dopamine-agonists may decrease cortisol levels in a number of these patients, strengthening the current (re)emerging interest in DRs as possible targets for medical treatment of CS...
  21. ncbi request reprint Effect of different therapeutic modalities on spontaneous GH secretion in acromegalic patients
    Eugenia Resmini
    Department of Endocrinological and Metabolic Sciences, University of Genova, Genova, Italy
    Clin Endocrinol (Oxf) 63:294-7. 2005
    ....
  22. ncbi request reprint Dopamine receptor expression and function in corticotroph pituitary tumors
    Rosario Pivonello
    Department of Internal Medicine, Erasmus Medical Center, 3015 GE Rotterdam, The Netherlands
    J Clin Endocrinol Metab 89:2452-62. 2004
    ..The effectiveness of cabergoline in normalizing cortisol secretion in 40% of cases supports its therapeutic use in the management of Cushing's disease...
  23. doi request reprint The pathology of the ulnar nerve in acromegaly
    Alberto Tagliafico
    Department of Radiology R, University of Genova, Viale Benedetto XV, 6, I 16132 Genova, Italy
    Eur J Endocrinol 159:369-73. 2008
    ..Acromegalic patients may complain of sensory disturbances in their hands. Cubital tunnel syndrome, the ulnar nerve neuropathy at the cubital tunnel (UCT), in acromegalic patients has never been reported...
  24. doi request reprint β-Arrestin 1 and 2 and G protein-coupled receptor kinase 2 expression in pituitary adenomas: role in the regulation of response to somatostatin analogue treatment in patients with acromegaly
    Federico Gatto
    Erasmus Medical Center, Room Ee 530b, Doctor Molewaterplein 50, 3015 GE Rotterdam, The Netherlands
    Endocrinology 154:4715-25. 2013
    ..Arrestin 1 and GRK2 seem to have a role in modulating GH secretion during SSA treatment. ..
  25. doi request reprint Biochemical diagnosis and assessment of disease activity in acromegaly: a two-decade experience
    Francesco M Minuto
    Department of Endocrine and Medical Sciences, University of Genova, Viale Benedetto XV 6, 16132, Genoa, Italy
    Pituitary 15:215-21. 2012
    ..In this case, the basal and T120 GH values can replace multiple sampling. Different treatment modalities do not influence the discordance rate between GH and IGF-I...
  26. doi request reprint In vivo and in vitro response to octreotide LAR in a TSH-secreting adenoma: characterization of somatostatin receptor expression and role of subtype 5
    Federico Gatto
    Department of Endocrine and Medical Sciences DiSEM and Center of Excellence for Biomedical Research, University of Genova, Viale Benedetto XV, 6, 16132 Genova, Italy
    Pituitary 14:141-7. 2011
    ..The role of D2R should be further explored considering that the presence of D2R can influence SSTRs functionality...
  27. ncbi request reprint Assessment of disease activity in acromegaly by means of a single blood sample: comparison of the 120th minute postglucose value with spontaneous GH secretion and with the IGF system
    Francesco Minuto
    Department of Endocrinology and Metabolism, University of Genova, Genova, Italy
    Clin Endocrinol (Oxf) 61:138-44. 2004
    ..With the aim of simplifying the follow-up protocol in these patients we also tested if one single sample taken after glucose load could replace the nadir value...
  28. doi request reprint Immunoreactivity score using an anti-sst2A receptor monoclonal antibody strongly predicts the biochemical response to adjuvant treatment with somatostatin analogs in acromegaly
    Federico Gatto
    Department of Internal Medicine, Erasmus MC, 3015 GE Rotterdam, The Netherlands
    J Clin Endocrinol Metab 98:E66-71. 2013
    ..Recently, a new rabbit monoclonal anti-sst2A antibody (clone UMB-1) has been validated as a reliable method to selectively detect sst2A protein levels in formalin-fixed tissues...
  29. doi request reprint Increased mammographic breast density in acromegaly: quantitative and qualitative assessment
    Alberto Tagliafico
    Department of Radiology, National Institute for Cancer Research IST, University of Genova, Genova 16132, Italy
    Eur J Endocrinol 164:335-40. 2011
    ..Mammographic density is a strong independent risk factor for breast cancer, whose prevalence in acromegaly is still controversial...
  30. doi request reprint Effect of environment on growth: auxological and hormonal parameters in African and Italian children
    Mara Boschetti
    Department of Endocrinological and Medical Sciences, University of Genova, Genova, Italy
    Growth Horm IGF Res 19:238-41. 2009
    ....
  31. doi request reprint Secondary diabetes associated with principal endocrinopathies: the impact of new treatment modalities
    Eugenia Resmini
    Department of Endocrinology and Medical Sciences, Center of Excellence for Biomedical Research, University of Genoa, Viale Benedetto XV, 6, 16132, Genoa, Italy
    Acta Diabetol 46:85-95. 2009
    ..Indeed, it has been demonstrated that insulin glargine, given once daily, reduces the risk of hypoglycaemia compared with other formulations, and can facilitate a more aggressive insulin treatment in this class of patients...
  32. ncbi request reprint [Somatostatin receptors in immune system cells]
    D Ferone
    Dipartimento di Scienze Endocrinologiche e Metaboliche, Universita degli Studi, Genova, Italy
    Minerva Endocrinol 26:165-73. 2001
    ..The expression of ssR has been found in vivo and in vitro, also in pathological sites in patients with autoimmune and granulomatous diseases like rheumatoid arthritis and sarcoidosis...
  33. pmc Five-year longitudinal evaluation of quality of life in a cohort of patients with differentiated thyroid carcinoma
    Massimo Giusti
    Department of Endocrine and Medical Sciences, University of Genoa, I 16100 Genoa, Italy
    J Zhejiang Univ Sci B 12:163-73. 2011
    ..Our data indicate that special attention should be paid to QoL in older DTC subjects and those with more severe staging on diagnosis...
  34. doi request reprint Ultrasound of peripheral nerves in acromegaly: changes at 1-year follow-up
    Eugenia Resmini
    Department of Endocrinology and Medical Sciences DiSEM, Center of Excellence for Biomedical Research, University of Genoa, Genoa, Italy
    Clin Endocrinol (Oxf) 71:220-5. 2009
    ..We have previously demonstrated peripheral nerve enlargement in acromegaly...
  35. ncbi request reprint Novel insights in dopamine receptor physiology
    Rosario Pivonello
    Departments of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands, Molecular and Clinical Endocrinology and Oncology, Federico II University, Via Sergio Pansini, 5, 80131 Naples, Italy
    Eur J Endocrinol 156:S13-21. 2007
    ..In addition, the recent findings on the relationship between dopamine receptors and neuroendocrine tumors are summarized...
  36. doi request reprint Vitamin D increases circulating IGF1 in adults: potential implication for the treatment of GH deficiency
    Pietro Ameri
    Internal Medicine Unit, Department of Internal Medicine, Centre of Excellence for Biomedical Research, IRCCS AOU San Martino IST, University of Genova, Viale Benedetto XV, 6, 16132 Genova, Italy
    Eur J Endocrinol 169:767-72. 2013
    ..Previous studies suggested that vitamin D modulates circulating IGF1. We investigated this effect in adults and its clinical relevance in the management of GH deficiency (GHD)...
  37. doi request reprint Diffuse endocrine system, neuroendocrine tumors and immunity: what's new?
    Pietro Ameri
    Department of Internal Medicine and Center of Excellence for Biomedical Research, University of Genoa, Genoa, Italy
    Neuroendocrinology 95:267-76. 2012
    ....
  38. doi request reprint Overexpression of stromal cell-derived factor 1 and its receptor CXCR4 induces autocrine/paracrine cell proliferation in human pituitary adenomas
    Federica Barbieri
    Laboratory of Pharmacology, Department of Oncology, Biology and Genetics, University of Genova, Viale Benedetto XV 2, Genoa, Italy
    Clin Cancer Res 14:5022-32. 2008
    ..We evaluated the expression of the chemokine stromal cell-derived factor 1 (SDF1) and its receptor CXCR4 in human pituitary adenomas and normal pituitary tissues and their role in cell proliferation...
  39. doi request reprint Leptin, ghrelin, and adiponectin evaluation in transsexual subjects during hormonal treatments
    Eugenia Resmini
    Department of Endocrinology and Medical Sciences, University of Genova, Viale Benedetto XV, 6, 16132 Genova, Italy
    J Androl 29:580-5. 2008
    ..This latter observation suggests that F-to-M transsexual patients could have a higher cardiovascular risk...
  40. doi request reprint Computed tomography colonography in acromegaly
    Eugenia Resmini
    Department of Endocrine and Medical Sciences, University of Genova, Viale Benedetto XV, 6, 16132 Genova, Italy
    J Clin Endocrinol Metab 94:218-22. 2009
    ..The aim of our study was to assess the feasibility and to evaluate the results of computed tomography (CT)-colonography in acromegaly...
  41. ncbi request reprint Somatostatin receptor expression in thymic tumors
    Diego Ferone
    Department of Endocrinology and Medical Sciences and Center of Excellence for Biomedical Research, University of Genova, Viale Benedetto XV, 6, Genova
    Front Biosci (Landmark Ed) 14:3304-9. 2009
    ..SRS provides immediate visualization of primary and metastatic lesions, while IHC reveals SSR subtype expression. This joined approach could help to select SS analogs beneficial for therapy...
  42. ncbi request reprint Sonographic depiction of trigger fingers in acromegaly
    Alberto Tagliafico
    Department of Radiology, University of Genoa, 16128 Genoa, Italy
    J Ultrasound Med 28:1441-6. 2009
    ..The purpose of this study was to compare the prevalence of trigger fingers in patients with acromegaly versus an unaffected control group...
  43. ncbi request reprint Ultrasound measurement of median and ulnar nerve cross-sectional area in acromegaly
    Alberto Tagliafico
    Department of Radiology, University of Genova, Viale Benedetto XV, 6, 16132 Genova, Italy
    J Clin Endocrinol Metab 93:905-9. 2008
    ..Acromegalic patients may complain of sensory disturbances in their hands...
  44. doi request reprint Interactions between vitamin D and IGF-I: from physiology to clinical practice
    Pietro Ameri
    Division of Endocrinology, Department of Medicine, New York University School of Medicine, New York, NY, USA
    Clin Endocrinol (Oxf) 79:457-63. 2013
    ..Current evidence indicates that, in breast tumours, vitamin D modulates the IGF-I/IGFBP ratio to decrease proliferation and increase apoptosis. ..
  45. doi request reprint Polycythemia as rare secondary direct manifestation of acromegaly: management and single-centre epidemiological data
    Gabriele Zoppoli
    Department of Internal Medicine, University of Genoa, Genoa, Italy
    Pituitary 15:209-14. 2012
    ..In conclusions, polycythemia can be a direct, albeit rare, secondary manifestation of acromegaly, that must be considered during the diagnostic work-up of acromegalic patients presenting with such disorder...
  46. pmc Metabolic and cardiovascular risk in patients with a history of differentiated thyroid carcinoma: A case-controlled cohort study
    Massimo Giusti
    Clinica Endocrinologica, Azienda Ospedaliera Universitaria San Martino, Genoa, Italy
    Thyroid Res 1:2. 2008
    ..These findings underline the need for adequate L-T4 titration...
  47. pmc Long-term outcome of low-activity radioiodine administration preceded by adjuvant recombinant human TSH pretreatment in elderly subjects with multinodular goiter
    Massimo Giusti
    Clinica Endocrinologica, Azienda Ospedaliera Universitaria San Martino, Genoa, Italy
    Thyroid Res 2:6. 2009
    ..The long-term effect of radioiodine therapy on thyroid volume (TV) and function after recombinant human (rh) TSH pre-treatment was evaluated...
  48. ncbi request reprint Somatostatin and dopamine receptors
    Diego Ferone
    Department of Endocrinology and Medical Sciences DiSEM, University of Genoa, Genoa, Italy
    Tumori 96:802-5. 2010
    ..Receptor profile characterization is crucial for the accurate selection of patients potentially responsive to a given therapy...
  49. ncbi request reprint Evidence of prolonged orocecal transit time and small intestinal bacterial overgrowth in acromegalic patients
    Eugenia Resmini
    Department of Endocrine and Medical Sciences DiSEM, University of Genova, Viale Benedetto XV, 6, Genova, Italy
    J Clin Endocrinol Metab 92:2119-24. 2007
    ..Gastrointestinal abnormalities in acromegaly include dolichomegacolon, slow colonic transit, and increased prevalence of colonic polyps. Conversely, no data are available on the small intestine...
  50. pmc Institutional experience of PTH evaluation on fine-needle washing after aspiration biopsy to locate hyperfunctioning parathyroid tissue
    Massimo Giusti
    Department of Endocrinology, San Martino University Hospital, I 16100 Genoa, Italy
    J Zhejiang Univ Sci B 10:323-30. 2009
    ..Of all the procedures used, PTH-FNAB appears to be the method of choice when the target is US suggestive and reachable. PTH-FNAB appears to be a useful method of guiding surgical intervention...
  51. ncbi request reprint Rationale for treating cancer with somatostatin analogs
    F Minuto
    Department of Endocrinology and Metabolism, University of Genoa, Genoa, Italy
    J Endocrinol Invest 26:117-9. 2003
  52. doi request reprint High prevalence of vitamin D deficiency and its association with left ventricular dilation: an echocardiography study in elderly patients with chronic heart failure
    P Ameri
    Department of Endocrinological and Medical Sciences, University of Genova, Genova, Italy
    Nutr Metab Cardiovasc Dis 20:633-40. 2010
    ..Differently from previous investigations, LV function was assessed by transthoracic echocardiography, to provide easily reproducible results...
  53. ncbi request reprint A unique association of clinical "persistent müllerian duct syndrome" and syringoid carcinoma of the perineal-scrotal skin: a consequence of urologic surgery?
    Umberto Goglia
    Department of Endocrinology and Medical Sciences and Centre of Excellence for Biomedical Research, San Martino Hospital, Genova, Italy
    J Androl 29:15-9. 2008
  54. doi request reprint Effects of uremia and inflammation on growth hormone resistance in patients with chronic kidney diseases
    Giacomo Garibotto
    Division of Nephrology, Department of Internal Medicine, Genoa, Italy
    Kidney Int 74:937-45. 2008
    ..Our results support the hypothesis that uremia with inflammation, but not uremia per se, inhibits downstream growth hormone signaling contributing to muscle atrophy...
  55. doi request reprint Identification of a novel mutation in exon 1 of androgen receptor gene in an azoospermic patient with mild androgen insensitivity syndrome: case report and literature review
    Umberto Goglia
    Department of Endocrinological and Medical Sciences, University of Genova, Genova, Italy
    Fertil Steril 96:1165-9. 2011
    ..To report a case of an azoospermic subject with mild androgen insensitivity syndrome (MAIS) and review the relevant literature...
  56. ncbi request reprint Neuroendocrine aspects of immunolymphoproliferative diseases
    D Ferone
    Department of Internal Medicine, Erasmus University, Rotterdam, The Netherlands
    Ann Oncol 12:S125-30. 2001
    ..These concepts increase the possibility of a wider antitumor treatment with ligands for neuroepeptide receptors than in established 'classic' neuroendocrine tumors...
  57. ncbi request reprint Serum osteoprotegerin and soluble receptor activator of nuclear factor kappaB ligand levels in patients with a history of differentiated thyroid carcinoma: a case-controlled cohort study
    Massimo Giusti
    UO Clinica Endocrinologica, Azienda Ospedaliera Universitaria San Martino, Genoa, Italy
    Metabolism 56:699-707. 2007
    ..The correlation between circulating OPG and RANK-L levels was not significant. The increase in OPG with age indicates its protective role in bone loss. The cause of bone loss after long-term L-T4 load will be more extensively studied...
  58. ncbi request reprint Well-differentiated pancreatic tumor/carcinoma: insulinoma
    Wouter W de Herder
    Department of Internal Medicine, Section of Endocrinology, Erasmus MC, Rotterdam, The Netherlands
    Neuroendocrinology 84:183-8. 2006
  59. ncbi request reprint In vivo and in vitro expression of somatostatin receptors in two human thymomas with similar clinical presentation and different histological features
    D Ferone
    Department of Internal Medicine, Erasmus Medical Center Rotterdam, The Netherlands
    J Endocrinol Invest 24:522-8. 2001
    ..Finally, although more cases need to be evaluated, the lack of detection of SS mRNA in the tumor presenting a more aggressive phenotype (B2 thymoma) might have physiopathological or prognostic significance...
  60. doi request reprint Somatostatin and dopamine receptor interaction in prostate and lung cancer cell lines
    M Arvigo
    Department of Endocrinological and Medical Sciences and Center of Excellence for Biomedical Research, Universita degli Studi di Genova, 16132 Genova, Italy
    J Endocrinol 207:309-17. 2010
    ..In conclusion, our data show a dynamic ligand-induced somatostatin and DA receptor interaction, which may be crucial for the antiproliferative effects of the new analogues...
  61. ncbi request reprint The role of somatostatin and somatostatin analogs in the pathophysiology of the human immune system
    V A S H Dalm
    Department of Internal Medicine, Erasmus MC, The Netherlands
    J Endocrinol Invest 26:94-102. 2003
  62. ncbi request reprint Pituitary tumor disappearance in a patient with newly diagnosed acromegaly primarily treated with octreotide LAR
    E Resmini
    Department of Endocrinological and Metabolic Sciences, University of Genoa, Genoa, Italy
    J Endocrinol Invest 28:166-9. 2005
    ..To our knowledge, this is the first case of complete radiological remission of pituitary tumor during octreotide LAR treatment in acromegaly...
  63. ncbi request reprint Replacement therapy and cardiovascular diseases
    M Boschetti
    Department of Endocrinology and Medical Sciences, University of Genoa, Genoa, Italy
    J Endocrinol Invest 31:85-90. 2008
    ..These data evidence the positive effects of GHRT in the prevention of premature atherosclerosis in adults with GHD, and encourage the early administration of replacement therapy...
  64. ncbi request reprint Somatostatin receptor scintigraphy in thoracic diseases
    P Ameri
    Department of Internal Medicine, University of Genoa, Genoa, Italy
    J Endocrinol Invest 30:889-902. 2007
    ..In this paper we review and discuss the role of SS receptor scintigraphy in diagnosis, staging or follow- up of thoracic SS receptor-positive lesions...
  65. ncbi request reprint The association of fasting insulin concentrations and colonic neoplasms in acromegaly: a colonoscopy-based study in 210 patients
    Annamaria Colao
    Department of Molecular, Clinical Endocrinology and Oncology, Section of Endocrinilogy, University Federico II of Naples, Via S Pansini 5, 80131 Naples, Italy
    J Clin Endocrinol Metab 92:3854-60. 2007
    ..Hyperinsulinemia is associated with colon carcinoma in the general population. Patients with acromegaly are considered to be at risk for developing colonic lesions and typically have hyperinsulinemia...
  66. ncbi request reprint Cabergoline plus lanreotide for ectopic Cushing's syndrome
    Rosario Pivonello
    N Engl J Med 352:2457-8. 2005
  67. ncbi request reprint In vivo and in vitro detection of dopamine d2 receptors in uveal melanomas
    Lisa Bodei
    Department of Nuclear Medicine, Erasmus University Medical Centre, Rotterdam, The Netherlands
    Cancer Biother Radiopharm 18:895-902. 2003
    ..Although further studies on larger series are needed, 123I-epidepride could represent a future tool to study the expression of D2R in other classes of neuroendocrine tumors...
  68. ncbi request reprint Systemic complications of acromegaly: epidemiology, pathogenesis, and management
    Annamaria Colao
    Department of Molecular and Clinical Endocrinology and Oncology, Federico II University of Naples, 80131 Naples, Italy
    Endocr Rev 25:102-52. 2004
    ..Finally, the most important cause of morbidity and functional disability of the disease is arthropathy, which can be reversed at an initial stage, but not if the disease is left untreated for several years...
  69. ncbi request reprint (99m)Technetium pentavalent dimercaptosuccinic acid scintigraphy in the follow-up of clinically nonfunctioning pituitary adenomas after radiotherapy
    Annamaria Colao
    Department of Clinical and Molecular Endocrinology and Oncology, University Federico II of Naples, Italy
    Clin Endocrinol (Oxf) 56:713-21. 2002
    ....
  70. ncbi request reprint Dopamine receptor expression and function in human normal adrenal gland and adrenal tumors
    Rosario Pivonello
    Department of Molecular and Clinical Endocrinology and Oncology, Federico II University, Via Sergio Pansini, 5, 80131 Naples, Italy
    J Clin Endocrinol Metab 89:4493-502. 2004
    ....