Alberto Falorni

Summary

Affiliation: University of Perugia
Country: Italy

Publications

  1. ncbi Therapy of adrenal insufficiency: an update
    Alberto Falorni
    Department of Internal Medicine, Section of Internal Medicine and Endocrine and Metabolic Sciences, University of Perugia, Via E dal Pozzo, Perugia, 06126, Italy
    Endocrine 43:514-28. 2013
  2. ncbi Viral and murine interleukin-10 are correctly processed and retain their biological activity when produced in tobacco
    Luisa Bortesi
    Scientific and Technologic Department, University of Verona, Strada Le Grazie 15, Verona, Italy
    BMC Biotechnol 9:22. 2009
  3. ncbi Measuring adrenal autoantibody response: interlaboratory concordance in the first international serum exchange for the determination of 21-hydroxylase autoantibodies
    Alberto Falorni
    Department of Internal Medicine, Section of Internal Medicine and Endocrine and Metabolic Sciences, University of Perugia, 06126 Perugia, Italy
    Clin Immunol 140:291-9. 2011
  4. ncbi Cytotoxic T lymphocyte antigen-4 Ala17 polymorphism is a genetic marker of autoimmune adrenal insufficiency: Italian association study and meta-analysis of European studies
    Annalisa Brozzetti
    Section of Internal Medicine and Endocrine and Metabolic Sciences, Department of Internal Medicine, University of Perugia, Via Enrico Dal Pozzo, 06126 Perugia, Italy
    Eur J Endocrinol 162:361-9. 2010
  5. ncbi Autoantibody responses in autoimmune ovarian insufficiency and in Addison's disease are IgG1 dominated and suggest a predominant, but not exclusive, Th1 type of response
    Annalisa Brozzetti
    Department of Internal Medicine, University of Perugia, Perugia, Italy
    Eur J Endocrinol 163:309-17. 2010
  6. ncbi Italian addison network study: update of diagnostic criteria for the etiological classification of primary adrenal insufficiency
    Alberto Falorni
    Department of Internal Medicine, University of Perugia, 06126 Perugia, Italy
    J Clin Endocrinol Metab 89:1598-604. 2004
  7. ncbi Progressive decline of residual follicle pool after clinical diagnosis of autoimmune ovarian insufficiency
    Alberto Falorni
    Department of Internal Medicine, Section of Internal Medicine and Endocrine and Metabolic Sciences, University of Perugia, Perugia, Italy
    Clin Endocrinol (Oxf) 77:453-8. 2012
  8. ncbi Corticotrope hypersecretion coupled with cortisol hypo-responsiveness to stimuli is present in patients with autoimmune endocrine diseases: evidence for subclinical primary hypoadrenalism?
    Roberta Giordano
    Department of Internal Medicine, Division of Endocrinology and Metabolism, University of Turin, Ospedale Molinette, C so Dogliotti 14 10126 Turin, Italy
    Eur J Endocrinol 155:421-8. 2006
  9. ncbi Mapping of human autoantibody epitopes on aromatic L-amino acid decarboxylase
    Paola Candeloro
    Department of Internal Medicine, Section of Internal Medicine and Endocrine and Metabolic Sciences, Via E dal Pozzo, 06126 Perugia, Italy
    J Clin Endocrinol Metab 92:1096-105. 2007
  10. ncbi Dehydroepiandrosterone, 17alpha-hydroxyprogesterone and aldosterone responses to the low-dose (1 micro g) ACTH test in subjects with preclinical adrenal autoimmunity
    Stefano Laureti
    Department of Internal Medicine and Endocrine and Metabolic Sciences, University of Perugia, Italy
    Clin Endocrinol (Oxf) 57:677-83. 2002

Collaborators

Detail Information

Publications26

  1. ncbi Therapy of adrenal insufficiency: an update
    Alberto Falorni
    Department of Internal Medicine, Section of Internal Medicine and Endocrine and Metabolic Sciences, University of Perugia, Via E dal Pozzo, Perugia, 06126, Italy
    Endocrine 43:514-28. 2013
    ..Future clinical trials of immunomodulation or immunoprevention will test the possibility to delay (or prevent) the autoimmune destruction of the adrenal gland in autoimmune Addison's disease...
  2. ncbi Viral and murine interleukin-10 are correctly processed and retain their biological activity when produced in tobacco
    Luisa Bortesi
    Scientific and Technologic Department, University of Verona, Strada Le Grazie 15, Verona, Italy
    BMC Biotechnol 9:22. 2009
    ..We investigated the ability of tobacco plants to produce high levels of biologically-active viral and murine IL-10...
  3. ncbi Measuring adrenal autoantibody response: interlaboratory concordance in the first international serum exchange for the determination of 21-hydroxylase autoantibodies
    Alberto Falorni
    Department of Internal Medicine, Section of Internal Medicine and Endocrine and Metabolic Sciences, University of Perugia, 06126 Perugia, Italy
    Clin Immunol 140:291-9. 2011
    ..A standardization international program for 21OHAb measurement is strongly needed...
  4. ncbi Cytotoxic T lymphocyte antigen-4 Ala17 polymorphism is a genetic marker of autoimmune adrenal insufficiency: Italian association study and meta-analysis of European studies
    Annalisa Brozzetti
    Section of Internal Medicine and Endocrine and Metabolic Sciences, Department of Internal Medicine, University of Perugia, Via Enrico Dal Pozzo, 06126 Perugia, Italy
    Eur J Endocrinol 162:361-9. 2010
    ..We tested the human leukocyte antigen (HLA)-independent association of CTLA4+49 (A/G) (Ala 17) and/or CTLA4 CT60 (A/G) polymorphism with AAD...
  5. ncbi Autoantibody responses in autoimmune ovarian insufficiency and in Addison's disease are IgG1 dominated and suggest a predominant, but not exclusive, Th1 type of response
    Annalisa Brozzetti
    Department of Internal Medicine, University of Perugia, Perugia, Italy
    Eur J Endocrinol 163:309-17. 2010
    ..The aim of the study was to analyze IgG subclass specificity of autoantibodies related to adrenal and ovarian autoimmunity...
  6. ncbi Italian addison network study: update of diagnostic criteria for the etiological classification of primary adrenal insufficiency
    Alberto Falorni
    Department of Internal Medicine, University of Perugia, 06126 Perugia, Italy
    J Clin Endocrinol Metab 89:1598-604. 2004
    ..Lastly, we developed a comprehensive flowchart for the classification of PAI for use in routine clinical practice...
  7. ncbi Progressive decline of residual follicle pool after clinical diagnosis of autoimmune ovarian insufficiency
    Alberto Falorni
    Department of Internal Medicine, Section of Internal Medicine and Endocrine and Metabolic Sciences, University of Perugia, Perugia, Italy
    Clin Endocrinol (Oxf) 77:453-8. 2012
    ..Anti-müllerian hormone (AMH) is the best marker of the residual follicular pool...
  8. ncbi Corticotrope hypersecretion coupled with cortisol hypo-responsiveness to stimuli is present in patients with autoimmune endocrine diseases: evidence for subclinical primary hypoadrenalism?
    Roberta Giordano
    Department of Internal Medicine, Division of Endocrinology and Metabolism, University of Turin, Ospedale Molinette, C so Dogliotti 14 10126 Turin, Italy
    Eur J Endocrinol 155:421-8. 2006
    ..We investigated the function of the hypothalamic-pituitary-adrenal axis in a group of patients with autoimmune diseases (AP) without any symptoms and signs of hypoadrenalism...
  9. ncbi Mapping of human autoantibody epitopes on aromatic L-amino acid decarboxylase
    Paola Candeloro
    Department of Internal Medicine, Section of Internal Medicine and Endocrine and Metabolic Sciences, Via E dal Pozzo, 06126 Perugia, Italy
    J Clin Endocrinol Metab 92:1096-105. 2007
    ..Little information is currently available on AADC autoantibody epitopes and on the interrelation between autoantibody-mediated inhibition of enzymatic activity and epitope specificity...
  10. ncbi Dehydroepiandrosterone, 17alpha-hydroxyprogesterone and aldosterone responses to the low-dose (1 micro g) ACTH test in subjects with preclinical adrenal autoimmunity
    Stefano Laureti
    Department of Internal Medicine and Endocrine and Metabolic Sciences, University of Perugia, Italy
    Clin Endocrinol (Oxf) 57:677-83. 2002
    ....
  11. ncbi Retrovirus-like long-terminal repeat DQ-LTR13 and genetic susceptibility to type 1 diabetes and autoimmune Addison's disease
    Giovanni Gambelunghe
    Department of Internal Medicine, University of Perugia, Via E dal Pozzo, I 06126 Perugia, Italy
    Diabetes 54:900-5. 2005
    ..We provide conclusive evidence that the genetic association of DQ-LTR13 with type 1 diabetes and AAD is primarily due to a LD with DQB1*0302 and DRB1*0403...
  12. ncbi Humoral responses in type 1 diabetes mellitus
    Alberto Falorni
    Department of Internal Medicine, University of Perugia, Perugia, Italy
    Rev Endocr Metab Disord 4:281-90. 2003
  13. ncbi BRAF(V599E) mutation is the leading genetic event in adult sporadic papillary thyroid carcinomas
    Efisio Puxeddu
    Dipartimento di Medicina Interna, Universita di Perugia, Perugia
    J Clin Endocrinol Metab 89:2414-20. 2004
    ....
  14. ncbi Association of genetic polymorphisms and autoimmune Addison's disease
    Alberto Falorni
    Department of Internal Medicine, Section of Internal Medicine and Endocrine and Metabolic Sciences, Via E dal Pozzo, 06126 Perugia, Italy
    Expert Rev Clin Immunol 4:441-56. 2008
    ..Other gene polymorphisms contributing to genetic risk for AAD are MHC2TA, the gene coding for class II transactivator, the master regulator of class II expression, cytotoxic T lymphocyte antigen-4, PTPN22 and the vitamin D receptor...
  15. ncbi Can NK cells be a therapeutic target in human type 1 diabetes?
    Francesco Dotta
    Diabetes Unit, Department of Internal Medicine, Endocrine and Metabolic Sciences and Biochemistry, University of Siena, Siena, Italy
    Eur J Immunol 38:2961-3. 2008
    ....
  16. ncbi Steroid-cell autoantibodies are preferentially expressed in women with premature ovarian failure who have adrenal autoimmunity
    Alberto Falorni
    Department of Internal Medicine, University of Perugia, Perugia, Italy
    Fertil Steril 78:270-9. 2002
    ..To determine the prevalence of steroid-cell autoantibodies, 3beta-hydroxysteroid dehydrogenase (3beta-HSD) antibodies, 17alpha-hydroxylase (17alpha-OH) antibodies, and P450 side-chain cleavage antibodies in premature ovarian failure...
  17. ncbi MICA A8: a new allele within MHC class I chain-related A transmembrane region with eight GCT repeats
    Giovanni Gambelunghe
    Department of Internal Medicine, Section of Internal Medicine and Endocrine and Metabolic Sciences, Perugia, Italy
    Hum Immunol 67:1005-7. 2006
    ..We named this allele, as a current nomenclature, MICA8...
  18. ncbi Diabetes-related antibodies in adult diabetic patients
    Alberto Falorni
    Department of Internal Medicine, University of Perugia, Via E dal Pozzo, I 06126 Perugia, Italy
    Best Pract Res Clin Endocrinol Metab 19:119-33. 2005
    ..GADA assay should be offered to every diabetic patient, and in cases of positivity screening for other autoimmune diseases should be carried out...
  19. ncbi Addison's disease
    Stefania Marzotti
    Department of Internal Medicine, Section of Internal Medicine and Endocrine and Metabolic Sciences, University of Perugia, Perugia, Italy
    Autoimmunity 37:333-6. 2004
  20. ncbi Inflammatory adipokines, high molecular weight adiponectin, and insulin resistance: a population-based survey in prepubertal schoolchildren
    Giuseppe Murdolo
    Section of Internal Medicine, Endocrine and Metabolic Sciences, Department of Internal Medicine, Perugia University, Perugia, Italy
    PLoS ONE 6:e17264. 2011
    ....
  21. ncbi Autoantibody profile and epitope mapping in latent autoimmune diabetes in adults
    Alberto Falorni
    Department of Internal Medicine, Section of Internal Medicine and Endocrine and Metabolic Sciences, University of Perugia, Perugia, Italy
    Ann N Y Acad Sci 958:99-106. 2002
    ..LADA should be considered a major component of the autoimmune polyendocrine syndromes, and screening for other autoimmune diseases should be performed in all LADA patients...
  22. ncbi Age-period-cohort analysis of 1990-2003 incidence time trends of childhood diabetes in Italy: the RIDI study
    Graziella Bruno
    Department of Internal Medicine, University of Turin, Turin, Italy
    Diabetes 59:2281-7. 2010
    ..To investigate age-period-cohort effects on the temporal trend of type 1 diabetes in children age 0-14 years in Italian registries...
  23. ncbi CTLA-4-Ig regulates tryptophan catabolism in vivo
    Ursula Grohmann
    Department of Experimental Medicine, University of Perugia, 06126 Perugia, Italy
    Nat Immunol 3:1097-101. 2002
    ..These data suggest that modulation of tryptophan catabolism is a means by which CTLA-4 functions in vivo and that CTLA-4 acts as a ligand for B7 receptor molecules that transduce intracellular signals...
  24. ncbi Autoantibodies in autoimmune polyendocrine syndrome type II
    Alberto Falorni
    Department of Internal Medicine, Section of Internal Medicine and Endocrine and Metabolic Sciences, University of Perugia, 06126 Perugia, Italy
    Endocrinol Metab Clin North Am 31:369-89, vii. 2002
    ..Screening for other organ-specific autoimmune diseases should be performed in every patient with at least one major disease component of APS-II...
  25. ncbi Pharmacological causes of hyperprolactinemia
    Daria La Torre
    Department of Internal Medicine, Section of Internal Medicine and Endocrine and Metabolic Sciences, University of Perugia Perugia, Italy
    Ther Clin Risk Manag 3:929-51. 2007
    ....
  26. ncbi CTLA-4 gene polymorphism contributes to the genetic risk for latent autoimmune diabetes in adults
    Anna Cosentino
    Department of Internal Medicine, Section of Internal Medicine and Endocrine and Metabolic Sciences, University of Perugia, Perugia, Italy
    Ann N Y Acad Sci 958:337-40. 2002
    ..028). The results of our study show that LADA is positively associated with the CTLA-4 A/G genotype, similarly to T1DM, thus providing further supporting evidence of the autoimmune origin of this form of diabetes mellitus of the adult...