S Esposito

Summary

Affiliation: University of Milan
Country: Italy

Publications

  1. ncbi Differences in nasopharyngeal bacterial flora in children with nonsevere recurrent acute otitis media and chronic otitis media with effusion: implications for management
    Paola Marchisio
    Department of Pediatrics, University of Milan, Italy
    Pediatr Infect Dis J 22:262-8. 2003
  2. ncbi Management of paediatric Lyme disease in non-endemic and endemic areas: data from the Registry of the Italian Society for Pediatric Infectious Diseases
    S Esposito
    Pediatric Clinic 1, Department of Pathophysiology and Transplantation, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Via Commenda 9, 20122, Milan, Italy
    Eur J Clin Microbiol Infect Dis 32:523-9. 2013
  3. ncbi Can infants be protected by means of maternal vaccination?
    S Esposito
    Pediatric Clinic 1, Department of Pathophysiology and Transplantation, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    Clin Microbiol Infect 18:85-92. 2012
  4. ncbi Preventing influenza in younger children
    S Esposito
    Pediatric Clinic 1, Department of Pathophysiology and Transplantation, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    Clin Microbiol Infect 18:42-9. 2012
  5. ncbi Borrelia burgdorferi infection and Lyme disease in children
    Susanna Esposito
    Department of Maternal and Pediatric Sciences, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Via Commenda 9, 20122 Milan, Italy
    Int J Infect Dis 17:e153-8. 2013
  6. ncbi Debate around infection-dependent hemophagocytic syndrome in paediatrics
    Valentina Ansuini
    Pediatric Clinic 1, Department of Pathophysiology and Transplantation, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Via Commenda 9, 20122, Milan, Italy
    BMC Infect Dis 13:15. 2013
  7. ncbi Immunogenicity, safety and tolerability of vaccinations in premature infants
    Susanna Esposito
    Pediatric Clinic 1, Department of Pathophysiology and Transplantation, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    Expert Rev Vaccines 11:1199-209. 2012
  8. ncbi Should corticosteroids be used in bacterial meningitis in children?
    Susanna Esposito
    Pediatric Clinic, Department of Pathophysiology and Transplantation, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    Eur J Paediatr Neurol 17:24-8. 2013
  9. ncbi Pharmacotherapy for pneumococcal infections: an update
    Susanna Esposito
    Pediatric Clinic 1, Department of Pathophysiology and Transplantation, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Via Commenda 9, 20122 Milano, Italy
    Expert Opin Pharmacother 14:65-77. 2013
  10. ncbi The immunogenicity and safety of a single 0.5 mL dose of virosomal subunit influenza vaccine administered to unprimed children aged ≥6 to <36 months: data from a randomized, Phase III study
    Susanna Esposito
    Pediatric Clinic 1, Department of Pathophysiology and Transplantation, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Via Commenda 9, 20122 Milan, Italy
    Vaccine 30:7005-12. 2012

Detail Information

Publications139 found, 100 shown here

  1. ncbi Differences in nasopharyngeal bacterial flora in children with nonsevere recurrent acute otitis media and chronic otitis media with effusion: implications for management
    Paola Marchisio
    Department of Pediatrics, University of Milan, Italy
    Pediatr Infect Dis J 22:262-8. 2003
    ..The results of nasopharyngeal cultures should be taken into account to avoid treatment with drugs that are ineffective and likely to select resistant organisms...
  2. ncbi Management of paediatric Lyme disease in non-endemic and endemic areas: data from the Registry of the Italian Society for Pediatric Infectious Diseases
    S Esposito
    Pediatric Clinic 1, Department of Pathophysiology and Transplantation, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Via Commenda 9, 20122, Milan, Italy
    Eur J Clin Microbiol Infect Dis 32:523-9. 2013
    ..05). Paediatric LD is also present in areas of Italy in which it is not considered endemic, but knowledge concerning its management is generally poor among PID specialists and characterised by enormous gaps in non-endemic areas...
  3. ncbi Can infants be protected by means of maternal vaccination?
    S Esposito
    Pediatric Clinic 1, Department of Pathophysiology and Transplantation, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    Clin Microbiol Infect 18:85-92. 2012
    ..This review analyses the advantages and limitations of maternal immunization as revealed by experience and the main publications...
  4. ncbi Preventing influenza in younger children
    S Esposito
    Pediatric Clinic 1, Department of Pathophysiology and Transplantation, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    Clin Microbiol Infect 18:42-9. 2012
    ..However, further studies are needed to establish whether universal influenza vaccination in the first years of life should be recommended, and with which vaccine...
  5. ncbi Borrelia burgdorferi infection and Lyme disease in children
    Susanna Esposito
    Department of Maternal and Pediatric Sciences, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Via Commenda 9, 20122 Milan, Italy
    Int J Infect Dis 17:e153-8. 2013
    ..This review of the currently available data will evaluate what may be the best approach to the diagnosis and treatment of B. burgdorferi infection and disease in the pediatric population...
  6. ncbi Debate around infection-dependent hemophagocytic syndrome in paediatrics
    Valentina Ansuini
    Pediatric Clinic 1, Department of Pathophysiology and Transplantation, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Via Commenda 9, 20122, Milan, Italy
    BMC Infect Dis 13:15. 2013
    ....
  7. ncbi Immunogenicity, safety and tolerability of vaccinations in premature infants
    Susanna Esposito
    Pediatric Clinic 1, Department of Pathophysiology and Transplantation, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    Expert Rev Vaccines 11:1199-209. 2012
    ..However, there is an urgent need for further studies concerning the use of recently marketed vaccines and those that will be marketed in the near future...
  8. ncbi Should corticosteroids be used in bacterial meningitis in children?
    Susanna Esposito
    Pediatric Clinic, Department of Pathophysiology and Transplantation, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    Eur J Paediatr Neurol 17:24-8. 2013
    ....
  9. ncbi Pharmacotherapy for pneumococcal infections: an update
    Susanna Esposito
    Pediatric Clinic 1, Department of Pathophysiology and Transplantation, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Via Commenda 9, 20122 Milano, Italy
    Expert Opin Pharmacother 14:65-77. 2013
    ....
  10. ncbi The immunogenicity and safety of a single 0.5 mL dose of virosomal subunit influenza vaccine administered to unprimed children aged ≥6 to <36 months: data from a randomized, Phase III study
    Susanna Esposito
    Pediatric Clinic 1, Department of Pathophysiology and Transplantation, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Via Commenda 9, 20122 Milan, Italy
    Vaccine 30:7005-12. 2012
    ..Our results show that a single 0.5 mL dose effectively and safely provided long-term immunogenicity to all three influenza strains in unprimed children aged at least 6 to <36 months...
  11. ncbi Circulation of different rhinovirus groups among children with lower respiratory tract infection in Kiremba, Burundi
    S Esposito
    Pediatric Clinic 1, Department of Pathophysiology and Transplantation, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Via Commenda 9, 20122, Milan, Italy
    Eur J Clin Microbiol Infect Dis 31:3251-6. 2012
    ..01) and RV-C with wheezing (p < 0.05). In Burundi, RVs are frequently detected in children with LRTIs. RV-A seems to be the most important species and is identified mainly in patients with bronchitis and CAP...
  12. ncbi Adenovirus 36 infection and obesity
    Susanna Esposito
    Pediatric Clinic 1, Department of Pathophysiology and Transplantation, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    J Clin Virol 55:95-100. 2012
    ..If it is demonstrated that AD-36 does play a role in obesity, it will be important to investigate possible vaccines against the infection itself or antiviral drugs capable of inhibiting disease progression...
  13. ncbi Severe vitamin B12 deficiency in an exclusively breastfed 5-month-old Italian infant born to a mother receiving multivitamin supplementation during pregnancy
    Sophie Guez
    Pediatric Clinic 1, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milano, Italy
    BMC Pediatr 12:85. 2012
    ..In infants, vitamin B12 deficiency may be due to an inborn error of absorption and metabolism, or nutritional problems...
  14. ncbi Antibody response of healthy children to pandemic A/H1N1/2009 influenza virus
    Susanna Esposito
    Department of Maternal and Pediatric Sciences, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Via Commenda 9, 20122 Milan, Italy
    Virol J 8:563. 2011
    ....
  15. ncbi Antibiotic therapy for pediatric community-acquired pneumonia: do we know when, what and for how long to treat?
    Susanna Esposito
    Department of Maternal and Pediatric Sciences, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    Pediatr Infect Dis J 31:e78-85. 2012
    ..Finally, further efforts are needed to increase vaccination coverage against respiratory pathogens and to conduct prospective studies of their impact...
  16. ncbi Unsolved problems in the approach to pediatric community-acquired pneumonia
    Susanna Esposito
    Department of Maternal and Pediatric Sciences, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda, Ospedale Maggiore Policlinico, Milan, Italy
    Curr Opin Infect Dis 25:286-91. 2012
    ..This review discusses unsolved problems concerning pediatric community-acquired pneumonia (CAP) and identifies the areas of research that need to be developed...
  17. ncbi Live attenuated intranasal influenza vaccine
    Susanna Esposito
    Department of Maternal and Pediatric Sciences, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    Hum Vaccin Immunother 8:76-80. 2012
    ..Further studies are needed to solve these problems and to evaluate the possible role of LAIV in the annual vaccination of the general population...
  18. ncbi Recommendations for the use of influenza vaccine in pediatrics
    Susanna Esposito
    Department of Maternal and Pediatric Sciences, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    Hum Vaccin Immunother 8:102-6. 2012
    ....
  19. ncbi Viral shedding in children infected by pandemic A/H1N1/2009 influenza virus
    Susanna Esposito
    Department of Maternal and Pediatric Sciences, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    Virol J 8:349. 2011
    ....
  20. ncbi Clinical importance and impact on the households of oseltamivir-resistant seasonal A/H1N1 influenza virus in healthy children in Italy
    Susanna Esposito
    Department of Maternal and Pediatric Sciences, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    Virol J 7:202. 2010
    ....
  21. ncbi Collection by trained pediatricians or parents of mid-turbinate nasal flocked swabs for the detection of influenza viruses in childhood
    Susanna Esposito
    Department of Maternal and Pediatric Sciences, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    Virol J 7:85. 2010
    ..Moreover, the direct involvement of parents significantly increases patient acceptance, thus simplifying collection and suggesting that this novel swab design should be considered for epidemiological surveys and vaccine efficacy studies...
  22. ncbi Meropenem vs standard of care for treatment of late onset sepsis in children of less than 90 days of age: study protocol for a randomised controlled trial
    Irja Lutsar
    Institute of Microbiology, University of Tartu, Estonia
    Trials 12:215. 2011
    ..The study will start recruitment in September 2011; the total duration is of 24 months. TRIAL REGISTRATION: EudraCT 2011-001515-31...
  23. ncbi Knowledge of human papillomavirus infection and its prevention among adolescents and parents in the greater Milan area, Northern Italy
    Claudio Pelucchi
    Department of Epidemiology, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    BMC Public Health 10:378. 2010
    ..The aim of this study was to provide data on the knowledge of Italian adolescents and parents concerning human papillomavirus (HPV) infection and its prevention in order to allow the development of adequate training programmes...
  24. ncbi Five-year follow-up of children with perinatal HIV-1 infection receiving early highly active antiretroviral therapy
    Elena Chiappini
    Department of Pediatrics, University of Florence, Florence, Italy
    BMC Infect Dis 9:140. 2009
    ..Nevertheless, data about long-term follow-up of early treated children are lacking...
  25. ncbi The rational use of influenza vaccines in healthy children and children with underlying conditions
    Susanna Esposito
    Department of Maternal and Pediatric Sciences, University of Milan, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy
    Curr Opin Infect Dis 22:244-9. 2009
    ..This review discusses why influenza should be considered an important clinical problem even in healthy children, and what can be expected from the use of influenza vaccines in pediatrics...
  26. ncbi The global state of influenza in children
    Susanna Esposito
    Institute of Pediatrics, University of Milan Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy
    Pediatr Infect Dis J 27:S149-53. 2008
    ....
  27. ncbi Vaccines and preterm neonates: why, when, and with what
    Susanna Esposito
    Department of Maternal and Pediatric Sciences, Universita degli Studi di Milano, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy
    Early Hum Dev 85:S43-5. 2009
    ..It is therefore essential to make every effort to convince pediatricians and parents that compliance with these recommendations will not cause any clinical problems...
  28. ncbi Differences in vaccinations in European Union
    Susanna Esposito
    Institute of Pediatrics, University of Milan, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy
    Hum Vaccin 4:313-5. 2008
    ....
  29. ncbi Rhinosinusitis management in pediatrics: an overview
    S Esposito
    Department of Maternal and Pediatric Sciences, University of Milan, Fondazione IRCCS, Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy
    Int J Immunopathol Pharmacol 23:53-5. 2010
    ....
  30. ncbi From clinical practice to guidelines: how to recognize rhinosinusitis in children
    S Esposito
    Institute of Pediatrics, University of Milan, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy
    Pediatr Allergy Immunol 18:53-5. 2007
    ..Under these circumstances, computed tomography is the preferred evaluation. Together with their clinical judgment, these suggestions may be useful for pediatricians in diagnosing this common condition...
  31. ncbi Knowledge of vaccination of allergic children among Italian primary care pediatricians, hospital pediatricians and pediatric residents
    Susanna Esposito
    Department of Maternal and Pediatric Sciences, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Via Commenda 9, 20122 Milano, Italy
    Vaccine 28:7569-75. 2010
    ....
  32. ncbi Evaluation of a rapid bedside test for the quantitative determination of C-reactive protein
    Susanna Esposito
    Institute of Pediatrics, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, University of Milan, Italy
    Clin Chem Lab Med 43:438-40. 2005
    ....
  33. ncbi Clinical and socioeconomic impact of different types and subtypes of seasonal influenza viruses in children during influenza seasons 2007/2008 and 2008/2009
    Susanna Esposito
    Department of Maternal and Pediatric Sciences, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    BMC Infect Dis 11:271. 2011
    ..This study evaluates the clinical presentation and socio-economic impact of laboratory-confirmed influenza A/H1N1, A/H3N2 or B infection in children attending an Emergency Room because of influenza-like illness...
  34. ncbi Different influenza vaccine formulations and adjuvants for childhood influenza vaccination
    Susanna Esposito
    Department of Maternal and Pediatric Sciences, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Via Commenda 9, 20122 Milan, Italy
    Vaccine 29:7535-41. 2011
    ....
  35. ncbi Immunogenicity and safety of human papillomavirus-16/18 AS04-adjuvanted vaccine administered according to an alternative dosing schedule compared with the standard dosing schedule in healthy women aged 15 to 25 years: results from a randomized study
    Susanna Esposito
    Department of Maternal and Pediatric Sciences, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milano, Italy
    Pediatr Infect Dis J 30:e49-55. 2011
    ..This study (NCT00552279) evaluated the vaccine when administered according to an alternative dosing schedule (0-1-12 months) compared with the standard dosing schedule (0-1-6 months)...
  36. ncbi Impact on respiratory tract infections of heptavalent pneumococcal conjugate vaccine administered at 3, 5 and 11 months of age
    Susanna Esposito
    Institute of Pediatrics, University of Milan, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy
    Respir Res 8:12. 2007
    ..This study was designed to evaluate the impact of PCV-7 administered at 3, 5 and 11 months of age on respiratory tract infections in very young children...
  37. ncbi Influenza vaccination among healthcare workers in a multidisciplinary University hospital in Italy
    Susanna Esposito
    Institute of Pediatrics, University of Milan, IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy
    BMC Public Health 8:422. 2008
    ..The aim of this study was to evaluate the current vaccination status of the HCWs in one of Italy's largest multidisciplinary University Hospitals...
  38. ncbi Altered cardiac rhythm in infants with bronchiolitis and respiratory syncytial virus infection
    Susanna Esposito
    Department of Maternal and Pediatric Sciences, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    BMC Infect Dis 10:305. 2010
    ..The aim of this study was to verify the real frequency of heart involvement in patients with bronchiolitis associated with RSV infection, and whether infants with mild or moderate disease also risk heart malfunction...
  39. ncbi Mycoplasma pneumoniae and Chlamydia pneumoniae infections in children with pneumonia. Mowgli Study Group
    S Esposito
    Paediatric Dept I, Istituto di Ricerca e di Cura a Carattere Scientifico, Maggiore Hospital, Milan, Italy
    Eur Respir J 17:241-5. 2001
    ..The priorities for future research include the development of rapid, easily accessible and cost-effective diagnostic tests useful for each episode of pneumonia in children...
  40. ncbi Clinical and socio-economic impact of influenza and respiratory syncytial virus infection on healthy children and their households
    S Esposito
    Institute of Pediatrics, Fondazione IRCCS 'Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, University of Milan, Milan, Italy
    Clin Microbiol Infect 11:933-6. 2005
    ..The fact that influenza has a similar global clinical impact on the community to that of RSV infection, but represents a greater socio-economic burden, may contribute to broadening the acceptance of influenza vaccination...
  41. ncbi Use of complementary and alternative medicine in children with recurrent acute otitis media in Italy
    P Marchisio
    Department of Maternal and Paediatric Sciences, Università degli Studi di Milano and Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    Int J Immunopathol Pharmacol 24:441-9. 2011
    ..Together with the fact that paediatricians are the main prescribers, this is worrying because of the current lack of evidence regarding the efficacy, safety and cost-effectiveness of CAM in the prevention of RAOM...
  42. ncbi Emerging role of Mycoplasma pneumoniae and Chlamydia pneumoniae in paediatric respiratory-tract infections
    N Principi
    Department of Paediatrics, Azienda Ospedaliera Istituti Clinici di Perfezionamento, Milan, Italy
    Lancet Infect Dis 1:334-44. 2001
    ..However, a number of therapeutic issues remain unsolved...
  43. ncbi Role of Mycoplasma pneumoniae and Chlamydia pneumoniae in children with community-acquired lower respiratory tract infections
    N Principi
    Pediatric Department I, University of Milan, Milan, Italy
    Clin Infect Dis 32:1281-9. 2001
    ..pneumoniae and/or C. pneumoniae plays a significant role in community-acquired LRTIs in children of all ages and that such infections have a more complicated course when not treated with adequate antimicrobial agents...
  44. ncbi Role of respiratory pathogens in infants hospitalized for a first episode of wheezing and their impact on recurrences
    S Bosis
    Institute of Paediatrics, University of Milan, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy
    Clin Microbiol Infect 14:677-84. 2008
    ..A high viral load seems to be strictly related to the likelihood of recurrence...
  45. ncbi Efficacy of increasing dosages of clarithromycin for treatment of experimental Mycoplasma pneumoniae pneumonia
    C Tagliabue
    Department of Maternal and Pediatric Sciences, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    J Antimicrob Chemother 66:2323-9. 2011
    ..We evaluated the efficacy of increasing dosages of clarithromycin for the optimized therapy of M. pneumoniae respiratory infection in a mouse model...
  46. ncbi Effectiveness of a propolis and zinc solution in preventing acute otitis media in children with a history of recurrent acute otitis media
    P Marchisio
    Department of Maternal and Pediatric Sciences, University of Milan, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    Int J Immunopathol Pharmacol 23:567-75. 2010
    ..No effect can be expected on respiratory infections other than AOM...
  47. ncbi Recurrent respiratory tract infections in pediatric age: a population-based survey of the therapeutic role of macrolides
    N Principi
    Pediatric Department I, University of Milan, Italy
    J Chemother 15:53-9. 2003
    ....
  48. ncbi Seasonal variations in nasopharyngeal carriage of respiratory pathogens in healthy Italian children attending day-care centres or schools
    P Marchisio
    Pediatric Department 1, University of Milan, Italy
    J Med Microbiol 50:1095-9. 2001
    ..However, although statistically significant, the difference was slight and had limited clinical relevance. Therefore, seasonal influence on the nasopharyngeal carriage of respiratory pathogens in healthy children was negligible...
  49. ncbi Hypertonic saline is more effective than normal saline in seasonal allergic rhinitis in children
    P Marchisio
    Department of Pathophysiology and Transplantation, University of Milan, Italy
    Int J Immunopathol Pharmacol 25:721-30. 2012
    ..Our data suggest that nasal irrigation with hypertonic saline might be included in the wide spectrum of therapies recommended for grass-pollen AR...
  50. ncbi Exhaled nitric oxide levels in children with chronic adenotonsillar disease
    S Torretta
    Otorhinolaryngological Clinic, Department of Specialist Surgical Sciences, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy
    Int J Immunopathol Pharmacol 24:471-80. 2011
    ....
  51. ncbi Role of atypical bacteria in children undergoing tonsillectomy because of severely recurrent acute tonsillopharyngitis
    S Esposito
    Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Institute of Pediatrics, University of Milan, Via Commenda 9, 20122, Milano, Italy
    Eur J Clin Microbiol Infect Dis 27:1233-7. 2008
    ..pneumoniae, and that tonsillectomy seems to be effective in reducing the recurrence of both AT and acute respiratory disease during 12 months follow-up postsurgery...
  52. ncbi Asthma in children: are chlamydia or mycoplasma involved?
    S Esposito
    Paediatric Department I, University of Milan, Italy
    Paediatr Drugs 3:159-68. 2001
    ..Carefully controlled randomised trials are clearly warranted to determine whether infection with atypical bacteria is really associated with asthma and to define the appropriate role of antimicrobial treatment...
  53. ncbi Effect of highly active antiretroviral therapy on cardiovascular involvement in children with human immunodeficiency virus infection
    Anna Plebani
    Institute of Pediatrics, University of Milan, Milan, Italy
    Pediatr Infect Dis J 23:559-63. 2004
    ....
  54. ncbi Zidovudine therapy and HIV type 1 mutations in children with symptomatic HIV type 1 infection: effect of switching to didanosine or zidovudine plus didanosine therapy. Italian Multicenter Study Group on HIV Mutations in Children
    N Principi
    Pediatric Department 4, University of Milan, Italy
    AIDS Res Hum Retroviruses 14:1653-9. 1998
    ..These results suggest that genotypic resistance assays, together with viral load, may prove useful for rational treatment decisions both at the start of therapy and with failure...
  55. ncbi Role of atypical bacteria and azithromycin therapy for children with recurrent respiratory tract infections
    Susanna Esposito
    Institute of Pediatrics, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, University of Milan, Milan, Italy
    Pediatr Infect Dis J 24:438-44. 2005
    ..CONCLUSIONS: Atypical bacteria seem to play a role among children with RRTIs, and prolonged azithromycin therapy can significantly improve the acute episodes and reduce the risk of recurrences...
  56. ncbi Insights into infectious otitis media
    P Marchisio
    Departments of Mother and Child, University of Milan, Policlinico, Mangiagalli e Regina Elena, Milan, Italy
    Int J Immunopathol Pharmacol 23:20-3. 2010
    ..In recent years new data have been gathered regarding different microbiological aspects of otitis media. This new knowledge may contribute toward the development and implementation of therapeutic and preventive strategies...
  57. ncbi Theoretic coverage of heptavalent pneumococcal conjugate vaccine in the prevention of community-acquired pneumonia in children in Italy
    Susanna Esposito
    Pediatric Department I, Via Commenda 9, 20122 Milan, Italy
    Vaccine 21:2704-7. 2003
    ..This study confirms the significant role of S. pneumoniae in pediatric CAP, and highlights the importance of pneumococcal conjugate vaccines in preventing it during the first years of life...
  58. ncbi Burden of influenza in healthy children and their households
    N Principi
    Institute of Paediatrics, University of Milan, Milan, Italy
    Arch Dis Child 89:1002-7. 2004
    ..A prospective, multicentre study was conducted to evaluate the burden of laboratory confirmed influenza in healthy children and their household contacts...
  59. ncbi Use of antimicrobial agents for community-acquired lower respiratory tract infections in hospitalised children
    S Esposito
    Pediatric Department 1, University of Milan, Italy
    Eur J Clin Microbiol Infect Dis 20:647-50. 2001
    ..In order to contain costs and limit the risk of resistant bacteria emerging, it is urgent that pediatricians and parents be educated in the proper use of antibiotics...
  60. ncbi Nasal nitric oxide in children with adenoidal hypertrophy: a preliminary study
    S Torretta
    Division of Otolaryngology, Department of Specialist Surgical Sciences, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy
    Int J Pediatr Otorhinolaryngol 74:689-93. 2010
    ....
  61. ncbi Guidelines for the diagnosis and treatment of acute and subacute rhinosinusitis in children
    S Esposito
    Institute of Pediatrics, University of Milan, Milan, Italy
    J Chemother 20:147-57. 2008
    ..These guidelines are based on the 125 that were considered truly relevant and reflect the most widely shared positions concerning the diagnosis and treatment of acute, subacute and recurrent rhinosinusitis in children...
  62. ncbi Diagnostic accuracy of the nasal obstruction index in detecting adenoid hypertrophy in children without allergy
    S Torretta
    Department of Specialist Surgical Sciences, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy
    Int J Pediatr Otorhinolaryngol 75:57-61. 2011
    ..The aim of this study was to verify the diagnostic accuracy of the NOI in detecting AH by comparing NOI scores with NFE findings in a selected series of non-allergic children affected by nasal obstruction...
  63. ncbi Nasopharyngeal carriage of Streptococcus pneumoniae in healthy children: implications for the use of heptavalent pneumococcal conjugate vaccine
    Paola Marchisio
    University of Milan, Via Commenda 9, 20122 Milan, Italy
    Emerg Infect Dis 8:479-84. 2002
    ..pneumoniae. Most isolated strains are covered by the heptavalent conjugate vaccine, especially in the first years of life, suggesting that its use could reduce the incidence of pneumococcal disease...
  64. ncbi Clinical presentation of meningococcal disease in childhood
    C Sabatini
    Pediatric Clinic 1, University of Milan, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    J Prev Med Hyg 53:116-9. 2012
    ....
  65. ncbi Meningitis complicated by subdural empyema and deafness caused by pneumoccoccal serotype 7F in a 17-month-old child: a case report
    S Bosis
    Pediatric Clinic 1, University of Milan, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    J Prev Med Hyg 53:98-100. 2012
    ..The 7F strain is not contained in PCV7 (the only vaccine on the market at the time of the onset of meningitis) but is included in the new pediatric 13-valent PCV, which may therefore prevent cases such as this in the future...
  66. ncbi New insights into pediatric rhinosinusitis
    N Principi
    Institute of Pediatrics, University of Milan, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy
    Pediatr Allergy Immunol 18:7-9. 2007
    ....
  67. ncbi Medical education and attitudes about acute otitis media guidelines: a survey of Italian pediatricians and otolaryngologists
    Paola Marchisio
    Department of Pediatrics, University of Milan, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy
    Pediatr Infect Dis J 28:1-4. 2009
    ..Limited data are available concerning medical education in acute otitis media (AOM), and the association between medical education and attitudes about AOM guidelines has never been explored...
  68. ncbi Role of vitamin D in children with respiratory tract infection
    S Esposito
    Pediatric Clinic 1, Department of Pathophysiology and Transplantation, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    Int J Immunopathol Pharmacol 26:1-13. 2013
    ....
  69. ncbi [Acute, subacute and recurrent bacterial rhinosinusitis in pediatrics: guidelines of the Study Group of the Italian Society for Pediatric Infectious Diseases (SITIP)]
    S Esposito
    Istituto di Pediatria, , Fondazione IRCCS Ospedale Maggiore Policlinico Mangiagalli e Regina Elena, Milano, Italy
    Minerva Pediatr 59:474-5. 2007
  70. ncbi Long-term pertussis-specific immunity after primary vaccination with a combined diphtheria, tetanus, tricomponent acellular pertussis, and hepatitis B vaccine in comparison with that after natural infection
    S Esposito
    Pediatric Department I, University of Milan, Milan, University of Palermo, Palermo, Italy
    Infect Immun 69:4516-20. 2001
    ..pertussis...
  71. ncbi The impact of steroids given with macrolide therapy on experimental Mycoplasma pneumoniae respiratory infection
    C Tagliabue
    Institute of Pediatrics, University of Milan Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ospedale Maggiore Policlinico, Milan, Italy
    J Infect Dis 198:1180-8. 2008
    ..We evaluated the efficacy of clarithromycin, dexamethasone, and combination therapy for M. pneumoniae respiratory infection...
  72. ncbi Effect of a rapid influenza diagnosis
    S Esposito
    Paediatric Department I, University of Milan, Italy
    Arch Dis Child 88:525-6. 2003
  73. ncbi Submental dermoid cyst: a rare clinical entity in early pediatric age
    P Capaccio
    Division of Otolaryngology, Department of Specialist Surgical Sciences, Fondazione I R C C S Ca Granda, Ospedale Maggiore Policlinico, University of Milan, Milan, Italy
    Pediatr Med Chir 33:92-4. 2011
    ..US followed by MRI is the gold standard for the non-invasive diagnostic differentiation of dermoid cysts from other submental swellings and submental excision remains the best surgical option...
  74. ncbi The Charta of Milan: basic criteria for the appropriate and accurate use of antibiotics: recommendations of the Italian Society of Chemotherapy
    F Scaglione
    Dipartimento de Farmacologia, Chemioterapia e Tossicologia, Universita Degli Studi de Milano, Italy
    J Chemother 21:475-81. 2009
    ..This article summarizes the recommendations drawn up by the Italian Society of Chemotherapy regarding the proper use of antimicrobial agents for infectious diseases...
  75. ncbi [Efficacy of the heptavalent pneumococcal vaccine against meningitis, pneumonia and acute otitis media in pediatric age. Theoretical coverage offered by the heptavalent conjugate vaccine in Italy]
    N Principi
    Clinica Pediatrica I, Universita degli Studi di Milano
    Ann Ig 14:21-30. 2002
    ..We hope that this vaccine can be systematically prescribed also in Italy: this could permit to reduce the number of both common and severe pneumococcal diseases at the moment largely present among italian children...
  76. ncbi Present and future of influenza prevention in pediatrics
    Nicola Principi
    Department of Maternal and Pediatric Sciences, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda, Ospedale Maggiore Policlinico, Via Commenda 9, 20122 Milano, Italy
    Expert Opin Biol Ther 11:641-53. 2011
    ..A number of different approaches seem to be promising in adults, but there is an urgent need for new strategies when using old vaccines in children or testing new vaccines in pediatric trials...
  77. ncbi Pediatric influenza prevention and control
    Nicola Principi
    Institute of Pediatrics, University of Milan, Milan, Italy
    Emerg Infect Dis 10:574-80. 2004
    ....
  78. ncbi Influenza A/H1N1 MF59-adjuvanted vaccine in preterm and term children aged 6 to 23 months
    Susanna Esposito
    Department of Maternal and Pediatric Sciences, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Via Commenda 9, 20122 Milano, Italy
    Pediatrics 127:e1161-8. 2011
    ..This study was designed to evaluate the immunogenicity, safety, and tolerability of a monovalent 2009 pandemic influenza A/H1N1 MF59-adjuvanted vaccine in children aged 6 to 23 months who had different gestational ages (GAs) at birth...
  79. ncbi Safety and immunogenicity of a 13-valent pneumococcal conjugate vaccine compared to those of a 7-valent pneumococcal conjugate vaccine given as a three-dose series with routine vaccines in healthy infants and toddlers
    Susanna Esposito
    Department of Maternal and Pediatric Sciences, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    Clin Vaccine Immunol 17:1017-26. 2010
    ....
  80. ncbi Unusual otolaryngological manifestations of certain systemic bacterial and fungal infections in children
    Lorenzo Pignataro
    Department of Otolaryngological and Ophthalmological Sciences, University of Milan, Fondazione IRCCS, Ospedale Maggiore Policlinico, Mangiagalli and Regina Elena, Milan, Italy
    Int J Pediatr Otorhinolaryngol 73:S33-7. 2009
    ..This paper reviews certain systemic bacterial and fungal diseases presenting ENT manifestations in the pediatric population from an otolaryngological perspective...
  81. ncbi Mycoplasma pneumoniae and Chlamydia pneumoniae cause lower respiratory tract disease in paediatric patients
    Nicola Principi
    Paediatric Department I, University of Milan, Milan, Italy
    Curr Opin Infect Dis 15:295-300. 2002
    ..Carefully randomized and controlled trials are clearly needed to examine the effectiveness of different antibiotics against M. pneumoniae or C. pneumoniae and the optimal duration of therapy in various patient populations...
  82. ncbi Detection of respiratory viruses and atypical bacteria in children's tonsils and adenoids
    Lorenzo Drago
    Laboratory of Microbiology, Department of Preclinical Sciences, LITA Vialba, Via GB Grassi 74, University of Milan, Milan 20157, Italy
    J Clin Microbiol 46:369-70. 2008
    ..Viruses were detected in 47.7% of the children and 37.3% of the specimens, with adenovirus and parainfluenza viruses being the most frequently detected microorganisms...
  83. ncbi Aetiology of acute pharyngitis: the role of atypical bacteria
    Susanna Esposito
    Institute of Paediatrics, IRCCS Maggiore Hospital, University of Milan, Milan, Italy
    J Med Microbiol 53:645-51. 2004
    ..pneumoniae seems to be mainly a co-pathogen. To avoid the risk of an incorrect therapeutic approach, simple laboratory investigations that allow rapid identification of M. pneumoniae infections are urgently needed...
  84. ncbi Evaluation of rapid assay for detection of Streptococcus pneumoniae urinary antigen among infants and young children with possible invasive pneumococcal disease
    Susanna Esposito
    Institute of Pediatrics, University of Milan, Via Commenda 9, 20122 Milan, Italy
    Pediatr Infect Dis J 23:365-7. 2004
    ....
  85. ncbi Impact of human bocavirus on children and their families
    Susanna Esposito
    Institute of Pediatrics, University of Milan, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Via Commenda 9, 20122 Milano, Italy
    J Clin Microbiol 46:1337-42. 2008
    ....
  86. ncbi Are we ready for universal influenza vaccination in paediatrics?
    Nicola Principi
    Institute of Paediatrics of the University of Milan, Italy
    Lancet Infect Dis 4:75-83. 2004
    ....
  87. ncbi Antigen-based assays for the identification of influenza virus and respiratory syncytial virus: why and how to use them in pediatric practice
    Nicola Principi
    Department of Maternal and Pediatric Sciences, University of Milan, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, 20122 Milano, Italy
    Clin Lab Med 29:649-60. 2009
    ..The most recently marketed tests are similarly effective in identifying viruses, and so pediatricians should choose those that are less expensive, less time consuming, and easier to perform and to interpret...
  88. ncbi Emerging resistance to antibiotics against respiratory bacteria: impact on therapy of community-acquired pneumonia in children
    Susanna Esposito
    Pediatric Department I, University of Milan, Via Commenda 9, 20122 Milan, Italy
    Drug Resist Updat 5:73-87. 2002
    ..We here discuss the prevalence of different etiologic agents in CAP of children, the diagnostic criteria, problems related to antibiotic resistance, therapeutic strategies, and future implications...
  89. ncbi Socioeconomic impact of influenza on healthy children and their families
    Nicola Principi
    Peditric Department I, Univeristy of Milan, Milan, Italy
    Pediatr Infect Dis J 22:S207-10. 2003
    ..Therefore it is difficult to conclude whether the socioeconomic impact of influenza justifies vaccinating all children regardless of age or underlying chronic disorders...
  90. ncbi Impact of human coronavirus infections in otherwise healthy children who attended an emergency department
    Susanna Esposito
    Institute of Pediatrics, University of Milan, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy
    J Med Virol 78:1609-15. 2006
    ..The quantitative and qualitative role of HCoV-HKU1 genotype A is apparently very marginal...
  91. ncbi Videoendoscopic rehabilitation of iatrogenous Stensen-duct-acquired atresia in a patient with ring chromosome 21 syndrome and drooling
    Pasquale Capaccio
    Department of Otorhinolaryngological and Ophthalmological Sciences, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, University of Milan, 20122 Milan, Italy
    J Pediatr Surg 43:e17-20. 2008
    ..Other therapeutical options such as botulinum toxin therapy might be considered for the management of drooling in such young patients...
  92. ncbi Paediatric community-acquired pneumonia: current concept in pharmacological control
    Nicola Principi
    Paediatric Department I, University of Milan, Via Commenda 9, 20122 Milano, Italy
    Expert Opin Pharmacother 4:761-77. 2003
    ..In order to avoid unnecessary antibiotic use and limit the spread of antibiotic resistance, consensus guidelines for the management of CAP in childhood should be developed and used by practitioners in their offices and hospitals...
  93. ncbi No evidence for the effectiveness of systemic corticosteroids in acute pharyngitis, community-acquired pneumonia and acute otitis media
    N Principi
    Pediatric Clinic 1, Department of Pathophysiology and Transplantation, Universita degli Studi di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Via Commenda 9, 20122 Milano, Italy
    Eur J Clin Microbiol Infect Dis 32:151-60. 2013
    ....
  94. ncbi Human metapneumovirus in paediatric patients
    N Principi
    Institute of Pediatrics, University of Milan, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy
    Clin Microbiol Infect 12:301-8. 2006
    ..Further studies are also required to properly define hMPV diagnosis, treatment and prevention strategies...
  95. ncbi Fatty acid composition of plasma lipids in HIV-infected children. Comparison with seroreverters
    C Agostoni
    Pediatric Department V, University of Milan, Italy
    Acta Paediatr 89:172-6. 2000
    ..Compared to age-matched seroreverter subjects, HIV-seropositive children show a lipid fatty acid status suggestive of relative LA deficiency and increased turnover of the PUFA series...
  96. ncbi Characteristics of Streptococcus pneumoniae and atypical bacterial infections in children 2-5 years of age with community-acquired pneumonia
    Susanna Esposito
    Pediatric Department I, Istituto Ricerca e Cura a Carattere Scientifico Maggiore Hospital, University of Milan, 20122 Milan, Italy
    Clin Infect Dis 35:1345-52. 2002
    ....
  97. ncbi Impact of human metapneumovirus in childhood: comparison with respiratory syncytial virus and influenza viruses
    Samantha Bosis
    Institute of Pediatrics, University of Milan, Milan, Italy
    J Med Virol 75:101-4. 2005
    ..Results show that hMPV is an emerging cause of acute respiratory infection in childhood, and may have a significant clinical and socioeconomic impact on children and their families...
  98. ncbi Immunogenicity, safety and tolerability of heptavalent pneumococcal conjugate vaccine administered at 3, 5 and 11 months post-natally to pre- and full-term infants
    Susanna Esposito
    Institute of Pediatrics, University of Milan, Via Commenda 9, 20122 Milano, Italy
    Vaccine 23:1703-8. 2005
    ..These findings support the use of the simplified schedule that includes three doses of PCV7 in both PT and FT infants, and suggest that this may reduce costs, as well as problems related to vaccine supply and administration...
  99. ncbi Clinical and economic impact of influenza vaccination on healthy children aged 2-5 years
    Susanna Esposito
    Institute of Pediatrics, Pediatric Department 1, University of Milan, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Via Commenda 9, 20122 Milano, Italy
    Vaccine 24:629-35. 2006
    ..However, larger and longer running study spanning multiple seasons may be warranted before suggesting the universal vaccination of this group of subjects...
  100. ncbi Effectiveness of influenza vaccination of children with recurrent respiratory tract infections in reducing respiratory-related morbidity within the households
    Susanna Esposito
    Department of Pediatric I, University of Milan, Via Commenda 9, 20122, Milan, Italy
    Vaccine 21:3162-8. 2003
    ..This study shows that the benefits of influenza vaccination extend to children with RRTIs and their family members and encourages to recommend its use in such children...
  101. ncbi Acute tonsillopharyngitis associated with atypical bacterial infection in children: natural history and impact of macrolide therapy
    Susanna Esposito
    Institute of Pediatrics, University of Milan, Milano, Italy
    Clin Infect Dis 43:206-9. 2006
    ..pneumoniae and C. pneumoniae may have a negative outcome with a high risk of recurrence of respiratory illness...