Giuseppe Esposito

Summary

Affiliation: University of Rome La Sapienza
Country: Italy

Publications

  1. doi request reprint Cannabidiol in inflammatory bowel diseases: a brief overview
    Giuseppe Esposito
    Department of Physiology and Pharmacology Vittorio Erspamer, Faculty of Pharmacy and Medicine, Sapienza University of Rome, Italy
    Phytother Res 27:633-6. 2013
  2. pmc The antiprotozoal drug pentamidine ameliorates experimentally induced acute colitis in mice
    Giuseppe Esposito
    Department of Physiology and Pharmacology Vittorio Erspamer, University Sapienza of Rome, P le Aldo Moro 5, 00185 Rome, Italy
    J Neuroinflammation 9:277. 2012
  3. pmc Palmitoylethanolamide exerts neuroprotective effects in mixed neuroglial cultures and organotypic hippocampal slices via peroxisome proliferator-activated receptor-α
    Caterina Scuderi
    Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy
    J Neuroinflammation 9:49. 2012
  4. doi request reprint Palmitoylethanolamide counteracts reactive astrogliosis induced by β-amyloid peptide
    Caterina Scuderi
    Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy
    J Cell Mol Med 15:2664-74. 2011
  5. pmc Cannabidiol reduces Aβ-induced neuroinflammation and promotes hippocampal neurogenesis through PPARγ involvement
    Giuseppe Esposito
    Department of Physiology and Pharmacology Vittorio Erspamer, Sapienza University of Rome, Rome, Italy
    PLoS ONE 6:e28668. 2011
  6. doi request reprint Cannabidiol in medicine: a review of its therapeutic potential in CNS disorders
    Caterina Scuderi
    Department of Physiology and Pharmacology V Erspamer, Sapienza University of Rome, Rome, Italy
    Phytother Res 23:597-602. 2009
  7. ncbi request reprint Genomic and functional profiling of human Down syndrome neural progenitors implicates S100B and aquaporin 4 in cell injury
    Giuseppe Esposito
    Department of Human Physiology and Pharmacology, Vittorio Erspamer Faculty of Pharmacy, University of Rome La Sapienza, Rome, Italy
    Hum Mol Genet 17:440-57. 2008
  8. pmc S100B induces tau protein hyperphosphorylation via Dickopff-1 up-regulation and disrupts the Wnt pathway in human neural stem cells
    Giuseppe Esposito
    Department of Human Physiology and Pharmacology V Erspamer, Sapienza University of Rome, Rome, Italy
    J Cell Mol Med 12:914-27. 2008
  9. ncbi request reprint Opposing control of cannabinoid receptor stimulation on amyloid-beta-induced reactive gliosis: in vitro and in vivo evidence
    Giuseppe Esposito
    Department of Human Physiology and Pharmacology, University of Rome La Sapienza, Rome, Italy
    J Pharmacol Exp Ther 322:1144-52. 2007

Collaborators

Detail Information

Publications9

  1. doi request reprint Cannabidiol in inflammatory bowel diseases: a brief overview
    Giuseppe Esposito
    Department of Physiology and Pharmacology Vittorio Erspamer, Faculty of Pharmacy and Medicine, Sapienza University of Rome, Italy
    Phytother Res 27:633-6. 2013
    ..This strategic interaction makes CBD as a potential candidate for the development of a new class of anti-IBD drugs...
  2. pmc The antiprotozoal drug pentamidine ameliorates experimentally induced acute colitis in mice
    Giuseppe Esposito
    Department of Physiology and Pharmacology Vittorio Erspamer, University Sapienza of Rome, P le Aldo Moro 5, 00185 Rome, Italy
    J Neuroinflammation 9:277. 2012
    ..The antiprotozoal drug pentamidine directly blocks S100B activity. We aimed to investigate the effect of pentamidine on intestinal inflammation using an animal model of dextran sodium sulphate (DSS)-induced acute colitis...
  3. pmc Palmitoylethanolamide exerts neuroprotective effects in mixed neuroglial cultures and organotypic hippocampal slices via peroxisome proliferator-activated receptor-α
    Caterina Scuderi
    Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy
    J Neuroinflammation 9:49. 2012
    ..Some of its pharmacological properties are considered to be dependent on the expression of peroxisome proliferator-activated receptors-α (PPARα)...
  4. doi request reprint Palmitoylethanolamide counteracts reactive astrogliosis induced by β-amyloid peptide
    Caterina Scuderi
    Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy
    J Cell Mol Med 15:2664-74. 2011
    ..These results indicate that PEA exhibits anti-inflammatory properties able to counteract Aβ-induced astrogliosis, and suggest novel treatment for neuroinflammatory/ neurodegenerative processes...
  5. pmc Cannabidiol reduces Aβ-induced neuroinflammation and promotes hippocampal neurogenesis through PPARγ involvement
    Giuseppe Esposito
    Department of Physiology and Pharmacology Vittorio Erspamer, Sapienza University of Rome, Rome, Italy
    PLoS ONE 6:e28668. 2011
    ..Moreover, due to its interaction at PPARγ, CBD was observed to stimulate hippocampal neurogenesis. All these findings report the inescapable role of this receptor in mediating CBD actions, here reported...
  6. doi request reprint Cannabidiol in medicine: a review of its therapeutic potential in CNS disorders
    Caterina Scuderi
    Department of Physiology and Pharmacology V Erspamer, Sapienza University of Rome, Rome, Italy
    Phytother Res 23:597-602. 2009
    ....
  7. ncbi request reprint Genomic and functional profiling of human Down syndrome neural progenitors implicates S100B and aquaporin 4 in cell injury
    Giuseppe Esposito
    Department of Human Physiology and Pharmacology, Vittorio Erspamer Faculty of Pharmacy, University of Rome La Sapienza, Rome, Italy
    Hum Mol Genet 17:440-57. 2008
    ....
  8. pmc S100B induces tau protein hyperphosphorylation via Dickopff-1 up-regulation and disrupts the Wnt pathway in human neural stem cells
    Giuseppe Esposito
    Department of Human Physiology and Pharmacology V Erspamer, Sapienza University of Rome, Rome, Italy
    J Cell Mol Med 12:914-27. 2008
    ..These findings propose a previously unrecognized link between S100B and tau hyperphosphorylation, suggesting S100B can contribute to NFT formation in AD and in all other conditions in which neuroinflammation may have a crucial role...
  9. ncbi request reprint Opposing control of cannabinoid receptor stimulation on amyloid-beta-induced reactive gliosis: in vitro and in vivo evidence
    Giuseppe Esposito
    Department of Human Physiology and Pharmacology, University of Rome La Sapienza, Rome, Italy
    J Pharmacol Exp Ther 322:1144-52. 2007
    ..The data support the assumption that compounds able to selectively block CB2 receptors may have therapeutic potential in controlling A beta-related pathology, due to their beneficial effects devoid of psychotropic consequences...