Giovanni Esposito

Summary

Affiliation: University of Padova
Country: Italy

Publications

  1. ncbi request reprint Complementary techniques: laser capture microdissection--increasing specificity of gene expression profiling of cancer specimens
    Giovanni Esposito
    Department of Oncological and Surgical Sciences, University of Padova, Via Gattamelata 64, Italy
    Adv Exp Med Biol 593:54-65. 2007
  2. doi request reprint A paclitaxel-hyaluronan bioconjugate targeting ovarian cancer affords a potent in vivo therapeutic activity
    Alessandra Banzato
    Department of Oncology and Surgical Sciences, University of Padova, Via Gattamelata 64, I 35128 Padua, Italy
    Clin Cancer Res 14:3598-606. 2008
  3. doi request reprint Notch3 signalling promotes tumour growth in colorectal cancer
    Valentina Serafin
    Department of Oncology and Surgical Sciences, University of Padua, 35128 Padova, Italy
    J Pathol 224:448-60. 2011
  4. ncbi request reprint Establishment and characterization of xenografts and cancer cell cultures derived from BRCA1 -/- epithelial ovarian cancers
    Stefano Indraccolo
    Istituto Oncologico Veneto, Padova, Italy
    Eur J Cancer 42:1475-83. 2006
  5. ncbi request reprint HYTAD1-p20: a new paclitaxel-hyaluronic acid hydrosoluble bioconjugate for treatment of superficial bladder cancer
    Antonio Rosato
    Department of Oncology and Surgical Sciences, Oncology Section, University of Padua, Padua, Italy
    Urol Oncol 24:207-15. 2006
  6. pmc Interruption of tumor dormancy by a transient angiogenic burst within the tumor microenvironment
    Stefano Indraccolo
    Department of Oncology and Surgical Sciences, University of Padova, 35128 Padova, Italy
    Proc Natl Acad Sci U S A 103:4216-21. 2006
  7. ncbi request reprint Interferon-alpha gene therapy by lentiviral vectors contrasts ovarian cancer growth through angiogenesis inhibition
    Stefano Indraccolo
    Department of Oncology and Surgical Sciences, University of Padua, Italy
    Hum Gene Ther 16:957-70. 2005
  8. ncbi request reprint Gene transfer in ovarian cancer cells: a comparison between retroviral and lentiviral vectors
    Stefano Indraccolo
    IST Viral and Molecular Oncology Section, Padova, Italy
    Cancer Res 62:6099-107. 2002
  9. doi request reprint Interferon-alpha counteracts the angiogenic switch and reduces tumor cell proliferation in a spontaneous model of prostatic cancer
    Luca Persano
    Oncology Section, Department of Oncology and Surgical Sciences, University of Padova, Padova I 35128, Italy
    Carcinogenesis 30:851-60. 2009
  10. pmc Hypoxia inducible factor-1alpha inactivation unveils a link between tumor cell metabolism and hypoxia-induced cell death
    Elena Favaro
    Department of Oncology and Surgical Sciences, Oncology Section, University of Padova, Padova, Italy
    Am J Pathol 173:1186-201. 2008

Collaborators

Detail Information

Publications21

  1. ncbi request reprint Complementary techniques: laser capture microdissection--increasing specificity of gene expression profiling of cancer specimens
    Giovanni Esposito
    Department of Oncological and Surgical Sciences, University of Padova, Via Gattamelata 64, Italy
    Adv Exp Med Biol 593:54-65. 2007
    ..This chapter describes the characteristics of the most widely utilized laser microdissection systems and their current applications...
  2. doi request reprint A paclitaxel-hyaluronan bioconjugate targeting ovarian cancer affords a potent in vivo therapeutic activity
    Alessandra Banzato
    Department of Oncology and Surgical Sciences, University of Padova, Via Gattamelata 64, I 35128 Padua, Italy
    Clin Cancer Res 14:3598-606. 2008
    ..This study was designed to evaluate the pharmacologic and biological properties of a paclitaxel-hyaluronan bioconjugate (ONCOFID-P) against IGROV-1 and OVCAR-3 human ovarian cancer xenografts following i.p. administration...
  3. doi request reprint Notch3 signalling promotes tumour growth in colorectal cancer
    Valentina Serafin
    Department of Oncology and Surgical Sciences, University of Padua, 35128 Padova, Italy
    J Pathol 224:448-60. 2011
    ..Altogether, these findings indicate that Notch3 can modulate the tumourigenic properties of CRC cells and contributes to sustained Notch activity in DLL4-expressing tumours...
  4. ncbi request reprint Establishment and characterization of xenografts and cancer cell cultures derived from BRCA1 -/- epithelial ovarian cancers
    Stefano Indraccolo
    Istituto Oncologico Veneto, Padova, Italy
    Eur J Cancer 42:1475-83. 2006
    ..The PD-OVCA1 and PD-OVCA2 ovarian cancer cell lines will provide a valuable tool for new experimental models for the study of BRCA1-associated tumour biology...
  5. ncbi request reprint HYTAD1-p20: a new paclitaxel-hyaluronic acid hydrosoluble bioconjugate for treatment of superficial bladder cancer
    Antonio Rosato
    Department of Oncology and Surgical Sciences, Oncology Section, University of Padua, Padua, Italy
    Urol Oncol 24:207-15. 2006
    ..To report the development of a new water-soluble paclitaxel-hyaluronic acid bioconjugate, HYTAD1-p20, for intravesical treatment of superficial bladder cancer...
  6. pmc Interruption of tumor dormancy by a transient angiogenic burst within the tumor microenvironment
    Stefano Indraccolo
    Department of Oncology and Surgical Sciences, University of Padova, 35128 Padova, Italy
    Proc Natl Acad Sci U S A 103:4216-21. 2006
    ..These findings may emphasize that tumor angiogenesis is a process requiring a higher amount of angiogenic factors for its induction than maintenance...
  7. ncbi request reprint Interferon-alpha gene therapy by lentiviral vectors contrasts ovarian cancer growth through angiogenesis inhibition
    Stefano Indraccolo
    Department of Oncology and Surgical Sciences, University of Padua, Italy
    Hum Gene Ther 16:957-70. 2005
    ....
  8. ncbi request reprint Gene transfer in ovarian cancer cells: a comparison between retroviral and lentiviral vectors
    Stefano Indraccolo
    IST Viral and Molecular Oncology Section, Padova, Italy
    Cancer Res 62:6099-107. 2002
    ..These findings indicate that lentiviral vectors deserve attention in the design of future gene therapy approaches to ovarian cancer aimed at achieving long-term expression of therapeutic genes...
  9. doi request reprint Interferon-alpha counteracts the angiogenic switch and reduces tumor cell proliferation in a spontaneous model of prostatic cancer
    Luca Persano
    Oncology Section, Department of Oncology and Surgical Sciences, University of Padova, Padova I 35128, Italy
    Carcinogenesis 30:851-60. 2009
    ..Since the angiogenic switch also marks progression of human prostatic cancer, these results highlight the potential of angiogenesis inhibitors for the development of chemoprevention strategies in high-risk individuals...
  10. pmc Hypoxia inducible factor-1alpha inactivation unveils a link between tumor cell metabolism and hypoxia-induced cell death
    Elena Favaro
    Department of Oncology and Surgical Sciences, Oncology Section, University of Padova, Padova, Italy
    Am J Pathol 173:1186-201. 2008
    ....
  11. ncbi request reprint Differential regulation of hypoxia-induced CXCR4 triggering during B-cell development and lymphomagenesis
    Erich Piovan
    Oncology Section, Department of Oncology and Surgical Sciences, University of Padova, Italy
    Cancer Res 67:8605-14. 2007
    ..The unresponsiveness of GC-derived lymphomatous B cells to CXCR4 triggering under hypoxia may have implications for the development and pathogenesis of GC-derived lymphoid tumors...
  12. doi request reprint Decreased expression and promoter methylation of the menin tumor suppressor in pancreatic ductal adenocarcinoma
    Ilaria Cavallari
    Department of Oncology and Surgical Sciences, University of Padova, Via Gattamelata 64, Padova 35128, Italy
    Genes Chromosomes Cancer 48:383-96. 2009
    ..These findings represent the first evidence that the MEN1 gene is a target of mutation and methylation in PDAC and that menin influences the cell cycle profile of duct cells...
  13. doi request reprint Relationship between tumor and plasma levels of hTERT mRNA in patients with colorectal cancer: implications for monitoring of neoplastic disease
    Liliana Terrin
    Department of Oncology and Surgical Sciences, Section of Oncology, University of Padova, Padova, Italy
    Clin Cancer Res 14:7444-51. 2008
    ..Expression of telomerase reverse transcriptase (hTERT) is essential to the oncogenic process and might be used as a molecular marker of neoplastic disease...
  14. ncbi request reprint In situ analysis of human menin in normal and neoplastic pancreatic tissues: evidence for differential expression in exocrine and endocrine cells
    Ilaria Cavallari
    Department of Oncology and Surgical Sciences, University of Padova, I 35128 Padova, Italy
    J Clin Endocrinol Metab 88:3893-901. 2003
    ..This report thus provides the first description of the expression pattern of menin in human pancreas in situ and lays the groundwork for further studies of other tissues and tumors...
  15. ncbi request reprint Efficient and cell specific knock-down of gene function in targeted C. elegans neurons
    Giovanni Esposito
    Istituto di Genetica e Biofisica, A Buzzati Traverso, CNR, Via P Castellino 111, 80131 Napoli, Italy
    Gene 395:170-6. 2007
    ....
  16. ncbi request reprint Encapsulated cells producing retroviral vectors for in vivo gene transfer
    Robert M Saller
    Institute of Molecular Virology, GSF Research Centre for Environment and Health, Oberschleissheim, Germany
    J Gene Med 4:150-60. 2002
    ..To circumvent this problem, retroviral vector packaging cells that permanently produce recombinant retroviral vector particles have been encapsulated...
  17. ncbi request reprint Metastatic transcriptional pattern revealed by gene expression profiling in primary colorectal carcinoma
    Antonello D'Arrigo
    Research and Innovation Company, Padova, Italy
    Int J Cancer 115:256-62. 2005
    ....
  18. doi request reprint Unexpected structural and functional consequences of the R33Q homozygous mutation in cardiac calsequestrin: a complex arrhythmogenic cascade in a knock in mouse model
    Nicoletta Rizzi
    Molecular Cardiology, IRCCS Maugeri Foundation, Pavia, Italy
    Circ Res 103:298-306. 2008
    ....
  19. ncbi request reprint Association between MDM2-SNP309 and age at colorectal cancer diagnosis according to p53 mutation status
    Chiara Menin
    IST Genova, Azienda Ospedaliera di Padova and Istituto Oncologico Veneto, Padova, Italy
    J Natl Cancer Inst 98:285-8. 2006
    ..0 years, 95% confidence interval = 1.0 to 16.0 years; P = .03 [two-sided Wilcoxon rank sum test]). Our data indicate that MDM2-SNP309 is a modifier of the age at colorectal cancer onset for patients whose tumors have a wild-type p53 gene...
  20. ncbi request reprint Signalling pathways in the nitric oxide donor-induced dopamine release in the striatum of freely moving rats: evidence that exogenous nitric oxide promotes Ca2+ entry through store-operated channels
    Gaia Rocchitta
    Department of Pharmacology, University of Sassari, viale S Pietro 43B, 07100 Sassari, Italy
    Brain Res 1023:243-52. 2004
    ....
  21. ncbi request reprint Identification of genes selectively regulated by IFNs in endothelial cells
    Stefano Indraccolo
    Department of Oncology and Surgical Sciences, Istituto Oncologico Veneto, Via Gattemelata 64, I 35128 Padua, Italy
    J Immunol 178:1122-35. 2007
    ..Moreover, we suggest that quantitative differences in the magnitude of the transcriptional activation of IFN-responsive genes could form the basis for cell-specific transcriptional signatures...