Sirio Dupont


Affiliation: University of Padova
Country: Italy


  1. Dupont S, Morsut L, Aragona M, Enzo E, Giulitti S, Cordenonsi M, et al. Role of YAP/TAZ in mechanotransduction. Nature. 2011;474:179-83 pubmed publisher
    ..These findings identify YAP/TAZ as sensors and mediators of mechanical cues instructed by the cellular microenvironment. ..
  2. Dupont S, Inui M, Newfeld S. Regulation of TGF-? signal transduction by mono- and deubiquitylation of Smads. FEBS Lett. 2012;586:1913-20 pubmed publisher
    ..Here we summarize and discuss recent work on Smad mono- and deubiquitylation. ..
  3. Aragona M, Panciera T, Manfrin A, Giulitti S, Michielin F, Elvassore N, et al. A mechanical checkpoint controls multicellular growth through YAP/TAZ regulation by actin-processing factors. Cell. 2013;154:1047-1059 pubmed publisher
    ..We propose that mechanical forces are overarching regulators of YAP/TAZ in multicellular contexts, setting responsiveness to Hippo, WNT, and GPCR signaling. ..