- A novel tRNA-associated locus (trl) from Helicobacter pylori is co-transcribed with tRNA(Gly) and reveals genetic diversityW G Dundon
Department of Microbiology, Trinity College, Dublin 2, Ireland
Microbiology 145:1289-98. 1999..pylori. Primer extension analysis showed that the trl locus is co-transcribed with tRNA(Gly). Analysis of the region between tRNA(Gly) and tRNA(Leu) in trl-negative isolates revealed additional genetic diversity among these isolates...
- Neutrophil-activating protein (HP-NAP) versus ferritin (Pfr): comparison of synthesis in Helicobacter pyloriW G Dundon
Centro CNR Biomembrane e Dipartimento di Scienze Biomediche, Universita di Padova, Italy
FEMS Microbiol Lett 199:143-9. 2001..Recombinant Pfr, as well as conferring resistance to iron and copper as previously reported, also conferred resistance to zinc overload when produced in E. coli...
- The Helicobacter pylori neutrophil-activating protein is an iron-binding protein with dodecameric structureF Tonello
Centro CNR Biomembrane and Dipartimento di Scienze Biomediche, Universita di Padova, I 35121, Italy
Mol Microbiol 34:238-46. 1999..We therefore conclude that HP-NAP is an unusual, small, ferritin that folds into a four-helix bundle that oligomerizes into dodecamers with a central hole capable of binding up to 500 iron atoms per oligomer...
- Helicobacter pylori neutrophil-activating protein stimulates tissue factor and plasminogen activator inhibitor-2 production by human blood mononuclear cellsP Montemurro
Dipartimento di Scienze Biomediche e Oncologia Umana, Sezione di Patologia Generale, University of Bari, Bari, Italy
J Infect Dis 183:1055-62. 2001..HP-NAP, by inducing the coordinate expression of cell procoagulant and antifibrinolytic activities, might favor fibrin deposition and contribute to the inflammatory reaction of gastric mucosa elicited by H. pylori...
- Virulence factors of Helicobacter pyloriW G Dundon
Centro CNR Biomembrane and Dipartimento di Scienze Biomediche, , Italy
Int J Med Microbiol 290:647-58. 2001..Recent advances in our understanding of the involvement of VacA, HP-NAP and the CagA/Type IV secretion system in the H. pylori-associated disease process are discussed in this review...