Research Topics
| A DoriaSummaryAffiliation: University of Padova Country: Italy Publications
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Detail Information
Publications
Prognosis of scleroderma renal crisis: a long-term observational studyFranco Cozzi
Rheumatology Unit, Department of Medicine, University of Padua, Padua, Italy
Nephrol Dial Transplant 27:4398-403. 2012..Our aim was to evaluate the prognosis of SRC in our cohort of scleroderma patients...
Autoinflammatory diseases: how to put the fire inside the body out?Andrea Doria
Division of Rheumatology, Department of Medicine, University of Padova, Padova, Italy
Autoimmun Rev 12:1-4. 2012..In this issue of Autoimmunity Reviews some novel and burning aspects of AIDs were covered and the relationship between AIDs and autoimmune diseases was discussed...
Autoinflammation and autoimmunity: bridging the divideA Doria
Division of Rheumatology, Department of Medicine, University of Padova, Italy
Autoimmun Rev 12:22-30. 2012....
Effect of pregnancy on serum cytokines in SLE patientsAndrea Doria
Division of Rheumatology, Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, Padova, 35128, Italy
Arthritis Res Ther 14:R66. 2012..The aim of this study was to evaluate an extensive panel of cytokines involved in immune regulation during pregnancy in patients with systemic lupus erythematosus (SLE) and in healthy women...
Myofiber stress-response in myositis: parallel investigations on patients and experimental animal models of muscle regeneration and systemic inflammationMaurizio Vitadello
Institute of Neuroscience Padova Section, Consiglio Nazionale delle Ricerche, Viale G, Colombo 3, 35121 Padova, Italy
Arthritis Res Ther 12:R52. 2010....
2nd conference on heart, rheumatism and autoimmunity, Pescara, Italy, May 19-20, 2005Andrea Doria
Division of Rheumatology, University of Padova, Via Guistiniani 2, Padova 35128, Italy
Autoimmun Rev 5:55-63. 2006....
[Rare autoimmune rheumatic illnesses during pregnancy. Systemic sclerosis, polymyositis/dermatomyositis and vasculitis]A Doria
Division of Rheumatology, Department of Medical and Surgical Sciences, University of Padova, Padova
Z Rheumatol 65:200, 202-6, 208. 2006..However, it is important to note that data on pregnancy outcome are very limited and, in the absence of prospective studies, most of the information derives from case reports and retrospective studies...
Lupus: improving long-term prognosisA Doria
Division of Rheumatology, Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
Lupus 17:166-70. 2008....
SLE diagnosis and treatment: when early is earlyAndrea Doria
Division of Rheumatology, Department of Clinical and Experimental Medicine, University of Padova, Italy
Autoimmun Rev 10:55-60. 2010..All these immune modulators seem to be particularly useful when introduced in an early stage of the disease...
Hormones, immune response, and pregnancy in healthy women and SLE patientsMargherita Zen
Division of Rheumatology, Clinical and Experimental Medicine, University of Padova, Padova, Italy
Swiss Med Wkly 140:187-201. 2010..This review focuses on hormonal-related cytokine changes observed during pregnancy in healthy subjects and SLE patients...
[Non SLE connective tissue diseases: general aspects and kidney]A Doria
Cattedra e Divisione di Reumatologia, Universita di Padova, Padova
G Ital Nefrol 22:S11-20. 2005..The interstitial lesions constitute the principal renal manifestations: interstitial infiltrates and small lymphocytes, which can be homogenous and massive. In polymyositis and dermatomyositis renal involvement is rare...
Challenges of lupus pregnanciesA Doria
Department of Clinical and Experimental Medicine, Division of Rheumatology, University of Padova, Via Giustiniani, 2, 35128 Padova, Italy
Rheumatology (Oxford) 47:iii9-12. 2008..All of these aspects are discussed in this review...
IgG anti-pentraxin 3 antibodies in systemic lupus erythematosusN Bassi
Division of Rheumatology, University of Padova, Via Giustiniani 2, Padua, Italy
Ann Rheum Dis 69:1704-10. 2010..To evaluate the prevalence and correlates of anti-pentraxin 3 (PTX3) antibodies in systemic lupus erythematosus (SLE)...
Infections as triggers and complications of systemic lupus erythematosusA Doria
Division of Rheumatology, Department of Clinical and Experimental Medicine, University of Padova, Italy
Autoimmun Rev 8:24-8. 2008....
Cardiac involvement in systemic lupus erythematosusA Doria
Division of Rheumatology, University of Padua, Padua, Italy
Lupus 14:683-6. 2005..Efforts should be made to control traditional risk factors as well as all other factors which could contribute to atherosclerotic plaque development...
Primary prevention of systemic lupus erythematosusAndrea Doria
Division of Rheumatology, Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
Nat Clin Pract Rheumatol 4:576-7. 2008..The strategies discussed aim to prevent both the occurrence of the disease and its complications...
Heart, rheumatism and autoimmunity: Milan, Italy. February 5-7, 2004Andrea Doria
Division of Rheumatology, University of Padova, Via Giustiniani 2, Padova 35128, Italy
Autoimmun Rev 3:337-54. 2004
Pregnancy, cytokines, and disease activity in systemic lupus erythematosusAndrea Doria
University of Padova, Padova, Italy
Arthritis Rheum 51:989-95. 2004..To evaluate levels of selected cytokines and soluble receptors involved in the humoral immune response during pregnancy in systemic lupus erythematosus (SLE) patients...
Long-term prognosis and causes of death in systemic lupus erythematosusAndrea Doria
Division of Rheumatology, Department of Clinical and Experimental Medicine, University of Padova, Italy
Am J Med 119:700-6. 2006..We studied survival rate, prognostic factors, and causes of death in patients with systemic lupus erythematosus (SLE), particularly focusing on the influence of disease severity...
Steroid hormones and disease activity during pregnancy in systemic lupus erythematosusAndrea Doria
Division of Rheumatology, University of Padova, Padua, Italy
Arthritis Rheum 47:202-9. 2002..Moreover, to investigate whether, during gestation, there is any relationship between steroid concentration and SLE activity...
Estrogens in pregnancy and systemic lupus erythematosusAndrea Doria
Division of Rheumatology, Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani, 2, 35128 Padova, Italy
Ann N Y Acad Sci 1069:247-56. 2006..This occurrence could lead to a lower-than-expected increase of IL-6, accounting for the low humoral immune response and the low disease activity observed in the third trimester of pregnancy in such patients...
Risk factors for subclinical atherosclerosis in a prospective cohort of patients with systemic lupus erythematosusA Doria
Division of Rheumatology, Department of Medical and Surgical Science, University of Padova, Italy
Ann Rheum Dis 62:1071-7. 2003..To evaluate traditional and non-traditional risk factors for subclinical atherosclerosis in systemic lupus erythematosus (SLE)...
Preventive strategies in systemic lupus erythematosusAndrea Doria
Division of Rheumatology, Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani, 2, 35128 Padova, Italy
Autoimmun Rev 7:192-7. 2008..Finally patients with mild disease carrying factors predictive of severe manifestations should be treated more aggressively than we have done up to now...
Health-related quality of life in Italian patients with systemic lupus erythematosus. II. Role of clinical, immunological and psychological determinantsA Doria
Cattedra e Divisione di Reumatologia, Dipartimento di Scienze Mediche e Chirurgiche, Via Giustiniani 2, 35128 Padua, Italy
Rheumatology (Oxford) 43:1580-6. 2004..To investigate the role of clinical, immunological and psychological variables in influencing the health-related quality of life (HRQOL) of Italian patients with systemic lupus erythematosus (SLE)...
Pre-pregnancy counselling of patients with vasculitisA Doria
Division of Rheumatology, Department of Medical and Surgical Sciences, University of Padova, Via Giustiniani, 2, 35128 Padova, Italy
Rheumatology (Oxford) 47:iii13-5. 2008..Moreover, organ failure or damage, due to previous disease activity, must also be taken into account since it can lead to adverse obstetrical and fetal outcomes...
Th2 immune deviation induced by pregnancy: the two faces of autoimmune rheumatic diseasesAndrea Doria
Division of Rheumatology, Department of Medical and Surgical Sciences, University of Padova, Via Giustiniani, 2, 35128 Padova, Italy
Reprod Toxicol 22:234-41. 2006..This review is focused on the disease course, gestational outcome and management of patients with SLE and RA during pregnancy...
Pregnancy in rare autoimmune rheumatic diseases: UCTD, MCTD, myositis, systemic vasculitis and Beçhet diseaseA Doria
Division of Rheumatology, Department of Medical and Surgical Sciences, University of Padova, Padova, Italy
Lupus 13:690-5. 2004....
Clinical implications of autoantibody screening in patients with autoimmune myositisA Ghirardello
University of Padova, Division of Rheumatology, Department of Clinical and Experimental Medicine, Italy
Autoimmunity 39:217-21. 2006..Anti-ARS non-Jo-1 antibodies seem to preferentially target patients with pulmonary fibrosis without overt myopathy...
oxLDL/beta2GPI complex and anti-oxLDL/beta2GPI in SLE: prevalence and correlatesN Bassi
Divsion of Rheumatology, Department of Medical and Surgical Sciences, University of Padova, Padova, Italy
Autoimmunity 42:289-91. 2009..Both IgG and IgM anti-complex Ab were associated with antiphospholipid (APL). In conclusion, the oxLDL/beta2GPI complex as well as Ab against the complex are prevalent in SLE where they seem to be involved in organ damage...
Positive and negative effects of thalidomide on refractory cutaneous lupus erythematosusC Briani
University of Padova, Department of Neurosciences, Via Giustiniani, 5, 35128, Padova, Italy
Autoimmunity 38:549-55. 2005..Thalidomide is used in cutaneous lupus erythematosus (CLE) refractory to conventional therapies. Peripheral neuropathy (PN) is the most severe side effect, but the incidence of PN and its relation to thalidomide dose are still unclear...
Health-related quality of life in Italian patients with systemic lupus erythematosus. I. Relationship between physical and mental dimension and impact of ageS Rinaldi
Cattedra e Divisione di Reumatologia, Dipartimento di Scienze Mediche e Chirurgiche, Via Giustiniani 2, 35128 Padua, Italy
Rheumatology (Oxford) 43:1574-9. 2004..In SLE, HRQOL tended to worsen with age. CONCLUSION: Both PCS and MCS contribute to the decrease in HRQOL in SLE patients. In SLE the mutual interaction between these two dimensions seems to be more relevant than in healthy people...
OxLDL/beta2GPI-anti-oxLDL/beta2GPI complex and atherosclerosis in SLE patientsN Bassi
Division of Rheumatology, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
Autoimmun Rev 7:52-8. 2007..Many other studies are required to explain the role of autoantibodies in the pathogenesis of ATS in SLE patients, because the characteristics of SLE seem to mask their effects for atherogenesis...
Anti-annexins autoantibodies: their role as biomarkers of autoimmune diseasesL Iaccarino
Division of Rheumatology, Department of Medicine, University of Padova, Via Giustiniani 2 35128 Padova, Italy
Autoimmun Rev 10:553-8. 2011..The metanalysis of studies published up to now showed that the Odds Ratio for having an ARD in anti-annexin XI positive patients was 5.08 (95% CI 2.06-12.58)...
Pentraxins, anti-pentraxin antibodies, and atherosclerosisN Bassi
Department of Medical and Surgical Sciences, University of Padova, Via Giustiniani, 2, 35128, Padova, Italy
Clin Rev Allergy Immunol 37:36-43. 2009..Antibodies against pentraxins have been demonstrated in patients with autoimmune diseases, but their role in atherogenesis is still controversial...
Anti-heart and anti-intercalated disk autoantibodies: evidence for autoimmunity in idiopathic recurrent acute pericarditisA L P Caforio
Division of Cardiology, Department of Cardiological, Thoracic and Vascular Sciences, Centro V Gallucci, University of Padova Policlinico, Via Giustiniani, 2, Padova 35128, Italy
Heart 96:779-84. 2010..Control groups included patients with non-inflammatory cardiac disease (NICD) (n=160), ischaemic heart failure (n=141) and normal subjects (n=270)...
Induction of the 'ASIA' syndrome in NZB/NZWF1 mice after injection of complete Freund's adjuvant (CFA)N Bassi
Division of Rheumatology, Department of Clinical and Experimental Medicine, University of Padova, Italy
Lupus 21:203-9. 2012..In conclusion, the injection of CFA in NZB/NZWF1 mice accelerated autoimmune manifestations resembling 'ASIA' syndrome in humans...
Increased titres of IgM anti-heparan sulfate antibody in Behçet's diseaseC Briani
Department of Neurosciences, University of Padova, Padova, Italy
Clin Exp Rheumatol 24:S104-7. 2006..The aim of our study was to measure serum anti-HS antibodies in patients with BD and to determine whether their presence correlates with disease activity or clinical manifestations...
Thalidomide and sensory neurotoxicity: a neurophysiological studyG Zara
Department of Neurosciences, University of Padova, Padova, Italy
J Neurol Neurosurg Psychiatry 79:1258-61. 2008....
Neurolupus is associated with anti-ribosomal P protein antibodies: an inception cohort studyC Briani
Department of Neurosciences, University of Padova, Padova, Italy
J Autoimmun 32:79-84. 2009..Our aim was to assess whether serum IgG Abs to ribosomal P proteins are associated with neuropsychiatric SLE...
Tumour necrosis factor alpha is expressed in refractory skin lesions from patients with subacute cutaneous lupus erythematosusS Zampieri
Department of Clinical and Experimental Medicine, University of Padova, Italy
Ann Rheum Dis 65:545-8. 2006..The tissue localisation of TNFalpha may represent a potential therapeutic target providing a new perspective in the treatment of refractory skin lesions in patients with SCLE...
[Myositis specific and myositis associated autoantibodies in idiopathic inflammatory myopathies: a serologic study of 46 patients]A Ghirardello
Dipartimento di Scienze Mediche e Chirurgiche, , Padova
Reumatismo 57:22-8. 2005..CONCLUSIONS: By means of analytically reliable methods, MSA was detected in 50% of our IIM patients. Searching for MSA in patients with IIM is recommended because of its diagnostic and prognostic value...
Polymyositis, dermatomyositis and malignancy: a further intriguing linkS Zampieri
Laboratory of Translational Myology of the Interdepartmental Research Center of Myology, c o Department of Biomedical Science, University of Padova, Italy
Autoimmun Rev 9:449-53. 2010....
Antinucleosome antibodies in SLE: a two-year follow-up study of 101 patientsA Ghirardello
Department of Medical and Surgical Sciences, Division of Rheumatology, University of Padova, Via Giustiniani, 2, 35128 Padova, Italy
J Autoimmun 22:235-40. 2004..Low antibody levels can be detected in SSc, whereas medium/high levels are highly specific for SLE. Their clinical relevance during the disease course and utility for monitoring the individual patient seem to be poor...
Nephritogenic-antinephritogenic antibody network in lupus glomerulonephritisA Doria
Division of Rheumatology, Department of Medicine, University of Padova, Italy
Lupus 21:1492-6. 2012..e. IgM anti-DNA) or other molecules (e.g. pentraxin 3). Thus, lupus nephritogenic-antinephritogenic antibodies orchestrate the balance between harm and defence of renal tissue...
[Detection of serum anti-B/B' UsnRNP antibodies in patients with connective tissue diseases by immunoblotting]A Ghirardello
Cattedra e Divisione di Reumatologia, Dipartimento di Scienze Mediche e Chirurgiche, , Italy
Reumatismo 54:324-30. 2002..Moreover, anti-B/B' is diagnostically specific for CTD with SLE features. Immunoblotting on human B lymphoid cells is a reliable method, in terms of sensitivity and specificity, for the detection of anti-Sm B/B' antibodies...
Vaccination of mice for research purpose: alum is as effective as and safer than complete Freund adjuvantN Bassi
Policlinico Universitario di Padova, Via Giustiniani, 2 35128, Padova
Reumatismo 64:380-7. 2012..Alum seems to be as effective as and safer than CFA as adjuvant, since it did not affect disease progression in immunized NZB/NZWF1 mice...
Update on idiopathic inflammatory myopathiesC Briani
University of Padova, Department of Neurosciences, Padova, Italy
Autoimmunity 39:161-70. 2006..This article summarizes the main clinical, laboratory, electrophysiological, immunological and histologic features as well as the therapeutic options of the inflammatory myopathies...
Thalidomide neurotoxicity: prospective study in patients with lupus erythematosusC Briani
Department of Neurosciences, Rheumatology Division, University of Padova, Italy
Neurology 62:2288-90. 2004..The median time free from PN was 14 months. PN occurred after 10 months in the majority of patients. No correlations were found between thalidomide cumulative dose and occurrence of PN (Mann-Whitney U test; p > 0.16)...
Idiopathic recurrent acute pericarditis: familial Mediterranean fever mutations and disease evolution in a large cohort of Caucasian patientsA Brucato
Department of Medicine, Niguarda Hospital Milano, Italy
Lupus 14:670-4. 2005..In conclusion, the prevalence of definite immunorheumatological diseases and the absence of the mutations linked to FMF reinforce the notion that idiopathic acute recurrent pericarditis is an autoimmune condition...
Atherosclerosis in psoriatic arthritisR Ramonda
Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
Autoimmun Rev 10:773-8. 2011..Some immunological factors which are involved in PsA can also contribute to atherosclerosis including C reactive protein (CRP), TNF-α, IFN-γ, IL-1, Il 6, IL23, and Th17...
[Prevalence and clinical features of fibromyalgia in systemic lupus erythematosus, systemic sclerosis and Sjögren's syndrome]P Ostuni
Dipartimento Scienze Mediche e Chirurgiche, Cattedra e Divisione di Reumatologia, Universita degli Studi, Padova, Italy
Minerva Med 93:203-9. 2002..The typical fibromyalgia findings encountered in these diseases were examined...
Risk factors for a first thrombotic event in antiphospholipid antibody carriers. A multicentre, retrospective follow-up studyA Ruffatti
Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padua, Padua, Italy
Ann Rheum Dis 68:397-9. 2009..To asses risk factors for a first thrombotic event in antiphospholipid antibody (aPL) positive carriers and evaluate the efficacy of prophylactic treatments...
Lupus erythematosus and the skinS Bano
Division of Dermatology, University of Padova, Italy
Clin Exp Rheumatol 24:S26-35. 2006....
The generalized torque approach for analyzing the results of pedaling testsA Doria
Department of Mechanical Engineering, University of Padova, Italy
J Biomech Eng 123:33-9. 2001..In order to assess the validity of the method, some experimental data are elaborated. Results show that the method can highlight the effect of training and the pedaling technique of an athlete...
[Post-traumatic arthritis in a patient with Jadassohn's anetoderma]C Circhetta
Cattedra e Divisione di Reumatologia, Universita degli Studi di Padova, Italia
Reumatismo 55:48-51. 2003..Diagnosis of post-traumatic arthritis in a young patient with genetic predisposition was assumed. Indeed septic arthritis and other possible cause of arthritis were ruled out...
Risk factors for a first thrombotic event in antiphospholipid antibody carriers: a prospective multicentre follow-up studyAmelia Ruffatti
Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padua, Padua, Italy
Ann Rheum Dis 70:1083-6. 2011..To assess risk factors for a first thrombotic event in confirmed antiphospholipid (aPL) antibody carriers and to evaluate the efficacy of prophylactic treatments...
Antibodies to muscle and ganglionic acetylcholine receptors (AchR) in celiac diseaseChiara Briani
Department of Neurosciences, University of Padova, Padova, Italy
Autoimmunity 41:100-4. 2008..Muscle AChR antibodies are found in patients with myasthenia gravis, and ganglionic AChR antibodies in patients with autoimmune autonomic neuropathy...
Cell stress response in skeletal muscle myofibersElena Tarricone
Department of Biomedical Sciences, University of Padova, Padova, Italy
Ann N Y Acad Sci 1069:472-6. 2006....
Expression of myositis specific autoantigens during post-natal myogenesisSandra Zampieri
Laboratory of Translational Myology, Interdepartmental Research Institute of Myology, c o Department of Biomedical Sciences, Padova, Italy
Neurol Res 30:145-8. 2008....
Diagnostic accuracy of currently available anti-double-stranded DNA antibody assays. An Italian multicentre studyAnna Ghirardello
Division of Rheumatology, University of Padova, Italy
Clin Exp Rheumatol 29:50-6. 2011..An Italian multicentre study was promoted in order to assess the accuracy of four anti-double-stranded DNA (dsDNA) antibody assays for SLE diagnosis and monitoring...
Subclinical myopathy in patients affected with newly diagnosed colorectal cancer at clinical onset of disease: evidence from skeletal muscle biopsiesS Zampieri
Laboratory of Translational Myology, Interdepartmental Research Center of Myology, C O, Department of Biomedical Science, University of Padova, Padova, Italy
Neurol Res 32:20-5. 2010....
Commercial blot assays in the diagnosis of systemic rheumatic diseasesAnna Ghirardello
Division of Rheumatology, Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
Autoimmun Rev 8:645-9. 2009..In this short review, our preliminary contribution on the validation of a commercial line blot assay for the laboratory diagnosis of autoimmune myositis is briefly reported...
Breast prostheses and connective tissue disease (CTD): myth or reality?F Bassetto
Plastic Surgery Clinic, University of Padova, Padova, Italy
Aesthetic Plast Surg 34:257-63. 2010....
Lack of multimer organization of von Willebrand factor in an acquired von Willebrand syndromeA Casonato
Department of Medical and Surgical Sciences, University of Padua Medical School, Padua, Italy
Br J Haematol 116:899-904. 2002....
Systemic lupus erythematosus, atherosclerosis, and autoantibodiesSandra Zampieri
Division of Rheumatology, University of Padova, Via Giustiniani 2, I-35128 Padua, Italy
Ann N Y Acad Sci 1051:351-61. 2005....
Anti-Jo-1 antibodiesSandra Zampieri
Department of Medical and Surgical Science Division of Rheumatology, University of Padova, Italy
Autoimmunity 38:73-8. 2005..The detection of this antibody is particularly useful in diagnosis and classification of IIM. Moreover, anti-Jo-1 serum levels strongly correlate with disease activity representing a good marker for disease monitoring...
Mycophenolate mofetil: what is its place in the treatment of autoimmune rheumatic diseases?Luca Iaccarino
Division of Rheumatology, Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani, 2, 35128 Padova, Italy
Autoimmun Rev 6:190-5. 2007..However, further studies are needed in order to determine its real place in the treatment of these conditions. In this paper, the use of MMF in different autoimmune rheumatic diseases is reviewed and discussed...
Anti-Mi-2 antibodiesAnna Ghirardello
Division of Rheumatology, Medical Clinics, Department of Medical and Surgical Sciences, University of Padova, Italy
Autoimmunity 38:79-83. 2005..A strong correlation with HLA-DR7 has been demonstrated.At the moment, optimal serologic testing is achieved by ELISA screening on recombinant Mi-2 antigen and confirmation of positive results on immunoblot...
Chronic fatigue syndrome: characteristics and possible causes for its pathogenesisNicola Bassi
Department of Rheumatology, University of Padova, Padova, Italy
Isr Med Assoc J 10:79-82. 2008..It has been demonstrated that impairment in vasoactive neuropeptide metabolism may explain the symptoms of CFS...
Infections and autoimmunity: the multifaceted relationshipPaolo Sfriso
Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani, 2, 35128 Padova, Italy
J Leukoc Biol 87:385-95. 2010..On the other hand, numerous evidences have emerged regarding the higher susceptibility of autoimmune patients to infections, possibly as a result of immunosuppressive therapy and treatment with biologic agents...
Influence of coping skills on health-related quality of life in patients with systemic lupus erythematosusSilvana Rinaldi
University of Padova, Padova, Italy
Arthritis Rheum 55:427-33. 2006..Strategies that show a passive attitude and joint pain seem to impair these patients' HRQOL...
SERPINB3, apoptosis and autoimmunityLaura Vidalino
Clinica Medica 5, Department of Clinical and Experimental Medicine, University of Padua, Italy
Autoimmun Rev 9:108-12. 2009..Since defective programmed cell death represents a critical feature of autoimmunity, the involvement of SERPINB3 in this pathological field deserves further studies...
Polymyositis-dermatomyositis and infectionsSandra Zampieri
University of Padova, Division of Rheumatology, Department of Clinical and Experimental Medicine, Italy
Autoimmunity 39:191-6. 2006..In this review, the increased risk of developing infections in these patients is also underlined and published data are reported...
Methods used to assess remission and low disease activity in rheumatoid arthritisFrancesca Ometto
Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, 35128 Padova, Italy
Autoimmun Rev 9:161-4. 2010..Thus, those reported by FDA are the only criteria for remission which consider radiographic arrest of the disease. This review aims to describe the criteria for RA remission and to discuss their advantages and limitations...
Antigen preparation for immunological studies in systemic autoimmune diseasesSandra Zampieri
Division of Rheumatology, Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
Ann N Y Acad Sci 1109:193-202. 2007..In this review an overview of the different biochemical methods of antigen preparation and the specific methodological applications is given, also describing potential critical aspects and benefits of the different protocols...
Diagnostic tests for antiribosomal p protein antibodies: a comparative evaluation of immunoblotting and ELISA assaysAnna Ghirardello
Division of Rheumatology, Department of Medical and Surgical Sciences, University of Padova, Italy
J Autoimmun 19:71-7. 2002..IB on P proteins extracted from human lymphoid cells is more sensitive than both ELISAs; IB and MAP ELISA perform better than the C-22 ELISA in determining weakly positive sera...
Evaluation of current methods for the measurement of serum anti double-stranded DNA antibodiesAnna Ghirardello
Division of Rheumatology, University of Padova, Italy
Ann N Y Acad Sci 1109:401-6. 2007..In the present article, an overview of current methods for anti-dsDNA antibody detection is presented, together with a look at the future trends in technologies newly employed in this field...
Inflammation and accelerated atherosclerosis: basic mechanismsAndrea Doria
Division of Rheumatology, Department of Medical and Surgical Science, University of Padua, Via Guistiniani 2, 35128 Padua, Italy
Rheum Dis Clin North Am 31:355-62, viii. 2005..The ability to immunomodulate atherosclerosis (currently only experimental) should lead to future research into the mechanisms and treatment of atherosclerosis, the leading cause of death in the Western world...
Long-term outcomes in difficult-to-treat patients with recurrent pericarditisAntonio Brucato
Department of Internal Medicine, Ospedale Niguarda, Milano, Department of Rheumatology, University of Padua, Italy
Am J Cardiol 98:267-71. 2006..3%. Mutations linked to familial Mediterranean fever were absent. In conclusion, in this large series of difficult patients with recurrent acute pericarditis and a very long follow-up, the long-term prognosis is good...
Premature coronary disease in systemic lupusAndrea Doria
N Engl J Med 350:1571-5; author reply 1571-5. 2004
The relevance of autoantigen source and cutoff definition in antichromatin (nucleosome) antibody immunoassaysDanilo Villalta
Immunologia Clinica e Virologia, Azienda Ospedaliera S Maria degli Angeli, Via Montereale 24, 33170 Pordenone, Italy
Ann N Y Acad Sci 1050:176-84. 2005....
Effect of adalimumab on neutrophil function in patients with rheumatoid arthritisFranco Capsoni
Department of Internal Medicine, Ospedale Maggiore Policlinico, IRCCS, University of Milan, Milan, Italy
Arthritis Res Ther 7:R250-5. 2005....
Thrombotic risk factors in primary antiphospholipid syndrome: a 5-year prospective studyMaurizio Turiel
Department of Cardiology, Istituto Ortopedico Galeazzi, University of Milan, Via Galeazzi 4, 20161 Milan, Italy
Stroke 36:1490-4. 2005..Because thromboembolic events are frequently observed in primary antiphospholipid syndrome (PAPS), we assessed the risk factors for new thrombotic episodes...
Anti-Ku antibodies in connective tissue diseases: clinical and serological evaluation of 14 patientsFranco Franceschini
Clinical Immunology Unit, Spedali Civili, University of Brescia, Italy
J Rheumatol 29:1393-7. 2002..To assess the clinical and serological associations of anti-Ku antibodies...
Organ-specific autoantibodies in patients with rheumatoid arthritis treated with adalimumab: a prospective long-term follow-upFabiola Atzeni
Rheumatology Unit, L Sacco University Hospital, Milan, Italy
Autoimmunity 41:87-91. 2008..Aim of our study was to assess the prevalence and concentration of a panel of organ-specific autoantibodies in patients with RA and to evaluate their relationship with clinical manifestations and treatment efficacy...
Autoimmunity and anti-TNF-alpha agentsFabiola Atzeni
Rheumatology Unit, Department of Rheumatology, University Hospital L Sacco, Via GB Grassi 74, 20157 Milan, Italy
Ann N Y Acad Sci 1051:559-69. 2005..3% and in 12.9% of adalimumab-treated RA patients. Only limited data on the induction of aPL antibodies during TNF-alpha blocking treatment are available...
Anti-thyroid antibodies and thyroid dysfunction in rheumatoid arthritis: prevalence and clinical valueFabiola Atzeni
Rheumatology Unit, L Sacco University Hospital, Milan, Italy
Autoimmunity 41:111-5. 2008..The aim of this study was to assess thyroid function as well as the prevalence and clinical value of anti-thyroid antibodies in patients with rheumatoid arthritis (RA)...
Anti-inflammatory and immunosuppressive drugs and reproductionMonika Østensen
Department of Rheumatology and Clinical Immunology Allergology, University Hospital of Bern, Switzerland
Arthritis Res Ther 8:209. 2006..Recommendations for drug treatment during pregnancy and lactation are given...
Autoantibodies against protective molecules--C1q, C-reactive protein, serum amyloid P, mannose-binding lectin, and apolipoprotein A1: prevalence in systemic lupus erythematosusYehuda Shoenfeld
Center for Autoimmune Diseases and Department of Medicine B, Chaim Sheba Medical Center, Tel Hashomer, Israel
Ann N Y Acad Sci 1108:227-39. 2007..These autoantibodies may play a pathogenic role in the development or perpetuation of autoimmunity in SLE...
Pregnancy and autoimmunity: maternal treatment and maternal disease influence on pregnancy outcomeAngela Tincani
Spedali Civili e Universita di Brescia, Brescia, Italy
Autoimmun Rev 4:423-8. 2005..However, information about long-term outcome of children exposed to immunosuppressive drugs "in utero" are still lacking and more efforts are needed in this research area...
A randomized pilot trial comparing cyclosporine and azathioprine for maintenance therapy in diffuse lupus nephritis over four yearsGabriella Moroni
Division of Nephrology, IRCCS Ospedale Maggiore, Via Commenda 15, 20122 Milano, Italy
Clin J Am Soc Nephrol 1:925-32. 2006..For patients with diffuse proliferative lupus nephritis, azathioprine or cyclosporine combined with corticosteroids demonstrated equal efficacy in the prevention of flares...
Organ specific-autoantibodies: their role as markers and predictors of diseasePiercarlo Sarzi-Puttini
Autoimmunity 41:1-10. 2008
Potential target of infliximab in autoimmune and inflammatory diseasesFabiola Atzeni
Rheumatology Unit, L Sacco Hospital, University of Milan, Via GB Grassi 74, 20157 Milan, Italy
Autoimmun Rev 6:529-36. 2007..A number of other more rare disorders also may be responsive to TNF blockade. We here review the current and prospective roles of infliximab in the treatment of autoimmune diseases and other conditions...
Novel biomarkers in autoimmune diseases: prolactin, ferritin, vitamin D, and TPA levels in autoimmune diseasesHedi Orbach
Department of Medicine B, Wolfson Medical Center, Holon, Israel
Ann N Y Acad Sci 1109:385-400. 2007..Hyperferritinemia may be used as an acute-phase reactant marker in autoimmune diseases mainly SLE. TPA may be used to indicate the tendency for malignancies...
1st International Conference on Cutaneous Lupus Erythematosus Düsseldorf, Germany, September 1-5, 2004Annegret Kuhn
Department of Dermatology, , , Germany
Autoimmun Rev 4:66-78. 2005
What is the role of rituximab in the treatment of rheumatoid arthritis?Fabiola Atzeni
Rheumatology Unit, L Sacco University Hospital, Via GB Grassi 74, 20157 Milan, Italy
Autoimmun Rev 6:553-8. 2007....
Mycophenolate mofetil in lupus glomerulonephritis: effectiveness and tolerabilityLuca Iaccarino
Division of Rheumatology, Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani, 2, 35128 Padova, Italy
Ann N Y Acad Sci 1110:516-24. 2007..Over the last few years, MMF has emerged as an alternative therapeutic regimen in lupus GLN, mainly for patients refractory to other therapies. These studies have shown that it is highly effective and generally well tolerated...
Anti-polymer antibodies are correlated with pain and fatigue severity in patients with fibromyalgia syndromePiercarlo Sarzi-Puttini
Rheumatology Unit, L Sacco University Hospital, Milan, Italy
Autoimmunity 41:74-9. 2008..To investigate the prevalence of antipolymer antibody (APA) in patients with fibromyalgia (FM) and to examine its association with FM severity symptoms...
Autoantibodies and prediction of reproductive failureYehuda Shoenfeld
Department of Internal Medicine B, Sheba Medical Center, Tel Hashomer, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Am J Reprod Immunol 56:337-44. 2006..To determine which autoantibodies are associated with reproductive failure...
Potential off-label use of infliximab in autoimmune and non-autoimmune diseases: a reviewFabiola Atzeni
Rheumatology Unit, L Sacco University Hospital, Via GB Grassi 74, 20157 Milan, Italy
Autoimmun Rev 4:144-52. 2005..We here review the current and prospective roles of infliximab in the treatment of autoimmune diseases and other conditions that do not currently have FDA or EMEA approval...
The mosaic of autoimmunity: hormonal and environmental factors involved in autoimmune diseases--2008Yehuda Shoenfeld
Department of Medicine B and Center for Autoimmune Diseases, Sheba Medical Center, Tel Hashomer, Israel
Isr Med Assoc J 10:8-12. 2008
