Claudia Donnini

Summary

Affiliation: University of Parma
Country: Italy

Publications

  1. pmc Improved production of heterologous proteins by a glucose repression-defective mutant of Kluyveromyces lactis
    Claudia Donnini
    Department of Genetics Anthropology Evolution, University of Parma, Parma, Italy
    Appl Environ Microbiol 70:2632-8. 2004
  2. doi request reprint Sym1, the yeast ortholog of the MPV17 human disease protein, is a stress-induced bioenergetic and morphogenetic mitochondrial modulator
    Cristina Dallabona
    Department of Genetics, Biology of Microorganisms, Anthropology and Evolution, University of Parma, Parma 43100, Italy
    Hum Mol Genet 19:1098-107. 2010
  3. ncbi request reprint Galactose transport in Kluyveromyces lactis: major role of the glucose permease Hgt1
    Enrico Baruffini
    Dipartimento di Genetica Antropologia Evoluzione, University of Parma, Parma, Italy
    FEMS Yeast Res 6:1235-42. 2006
  4. pmc Secretion of human serum albumin by Kluyveromyces lactis overexpressing KlPDI1 and KlERO1
    Tiziana Lodi
    Department of Genetics, Anthropology, and Evolution, University of Parma, Parco Area delle Scienze 11 A, I 43100 Parma, Italy
    Appl Environ Microbiol 71:4359-63. 2005
  5. ncbi request reprint Carboxylic acids permeases in yeast: two genes in Kluyveromyces lactis
    Tiziana Lodi
    Dipartimento di Genetica Antropologia Evoluzione, University of Parma, Viale delle Scienze 11 A, 43100 Parma, Italy
    Gene 339:111-9. 2004
  6. ncbi request reprint KNQ1, a Kluyveromyces lactis gene encoding a transmembrane protein, may be involved in iron homeostasis
    Emmanuela Marchi
    Dipartimento di Genetica, Biologia dei Microrganismi, Antropologia, Evoluzione, University of Parma, Parma, Italy
    FEMS Yeast Res 7:715-21. 2007
  7. ncbi request reprint Mutations in AAC2, equivalent to human adPEO-associated ANT1 mutations, lead to defective oxidative phosphorylation in Saccharomyces cerevisiae and affect mitochondrial DNA stability
    Flavia Fontanesi
    Department of Genetics Anthropology Evolution, University of Parma, 43100 Parma, Italy
    Hum Mol Genet 13:923-34. 2004
  8. ncbi request reprint Lactose-induced cell death of beta-galactosidase mutants in Kluyveromyces lactis
    Tiziana Lodi
    Dipartimento di Genetica Antropologia Evoluzione, University of Parma, 43100 Parma, Italy
    FEMS Yeast Res 5:727-34. 2005
  9. ncbi request reprint MTO1 mutations are associated with hypertrophic cardiomyopathy and lactic acidosis and cause respiratory chain deficiency in humans and yeast
    Enrico Baruffini
    Department of Life Sciences, University of Parma, Parma, Italy
    Hum Mutat 34:1501-9. 2013
  10. pmc Respiration-dependent utilization of sugars in yeasts: a determinant role for sugar transporters
    Paola Goffrini
    Istituto di Genetica, Universita degli Studi di Parma, Parma, Italy
    J Bacteriol 184:427-32. 2002

Collaborators

Detail Information

Publications13

  1. pmc Improved production of heterologous proteins by a glucose repression-defective mutant of Kluyveromyces lactis
    Claudia Donnini
    Department of Genetics Anthropology Evolution, University of Parma, Parma, Italy
    Appl Environ Microbiol 70:2632-8. 2004
    ..Therefore, the dgr151 strain may be a promising host for the production of heterologous proteins, especially when the hyperglycosylation of recombinant proteins must be avoided...
  2. doi request reprint Sym1, the yeast ortholog of the MPV17 human disease protein, is a stress-induced bioenergetic and morphogenetic mitochondrial modulator
    Cristina Dallabona
    Department of Genetics, Biology of Microorganisms, Anthropology and Evolution, University of Parma, Parma 43100, Italy
    Hum Mol Genet 19:1098-107. 2010
    ....
  3. ncbi request reprint Galactose transport in Kluyveromyces lactis: major role of the glucose permease Hgt1
    Enrico Baruffini
    Dipartimento di Genetica Antropologia Evoluzione, University of Parma, Parma, Italy
    FEMS Yeast Res 6:1235-42. 2006
    ..HGT1 expression was strongly induced by galactose and insensitive to glucose repression. This could explain the rapid adaptation to galactose observed in K. lactis after a shift from glucose to galactose medium...
  4. pmc Secretion of human serum albumin by Kluyveromyces lactis overexpressing KlPDI1 and KlERO1
    Tiziana Lodi
    Department of Genetics, Anthropology, and Evolution, University of Parma, Parco Area delle Scienze 11 A, I 43100 Parma, Italy
    Appl Environ Microbiol 71:4359-63. 2005
    ....
  5. ncbi request reprint Carboxylic acids permeases in yeast: two genes in Kluyveromyces lactis
    Tiziana Lodi
    Dipartimento di Genetica Antropologia Evoluzione, University of Parma, Viale delle Scienze 11 A, 43100 Parma, Italy
    Gene 339:111-9. 2004
    ..We conclude that KlJEN2 is the first yeast gene shown to encode a dicarboxylic acids permease...
  6. ncbi request reprint KNQ1, a Kluyveromyces lactis gene encoding a transmembrane protein, may be involved in iron homeostasis
    Emmanuela Marchi
    Dipartimento di Genetica, Biologia dei Microrganismi, Antropologia, Evoluzione, University of Parma, Parma, Italy
    FEMS Yeast Res 7:715-21. 2007
    ..KNQ1 amplification and deletion resulted in enhanced transcription of iron transport genes, suggesting, for the membrane-associated protein Knq1p, a new, unexpected role in iron homeostasis on which dithiothreitol tolerance may depend...
  7. ncbi request reprint Mutations in AAC2, equivalent to human adPEO-associated ANT1 mutations, lead to defective oxidative phosphorylation in Saccharomyces cerevisiae and affect mitochondrial DNA stability
    Flavia Fontanesi
    Department of Genetics Anthropology Evolution, University of Parma, 43100 Parma, Italy
    Hum Mol Genet 13:923-34. 2004
    ..cerevisiae is a suitable in vivo model to study the pathogenicity of the human ANT1 mutations and the pathophysiology leading to impairment of oxidative phosphorylation and damage of mtDNA integrity, as found in adPEO...
  8. ncbi request reprint Lactose-induced cell death of beta-galactosidase mutants in Kluyveromyces lactis
    Tiziana Lodi
    Dipartimento di Genetica Antropologia Evoluzione, University of Parma, 43100 Parma, Italy
    FEMS Yeast Res 5:727-34. 2005
    ..These mutants were unable to take up lactose. Indeed, lar1 mutation turned out to be allelic to LAC12. The high mutability of the LAC12 locus may be an advantage for survival of K. lactis whose main habitat is lactose-containing niches...
  9. ncbi request reprint MTO1 mutations are associated with hypertrophic cardiomyopathy and lactic acidosis and cause respiratory chain deficiency in humans and yeast
    Enrico Baruffini
    Department of Life Sciences, University of Parma, Parma, Italy
    Hum Mutat 34:1501-9. 2013
    ....
  10. pmc Respiration-dependent utilization of sugars in yeasts: a determinant role for sugar transporters
    Paola Goffrini
    Istituto di Genetica, Universita degli Studi di Parma, Parma, Italy
    J Bacteriol 184:427-32. 2002
    ..These results strongly suggest that the sugar uptake step is the major bottleneck in the fermentative assimilation of certain sugars in K. lactis and probably in many other yeasts...
  11. ncbi request reprint Allelic association of a dopamine transporter gene polymorphism with antisocial behaviour in heroin-dependent patients
    Gilberto Gerra
    Centro Studi Farmaco tossicodipendenze, Ser T, AUSL, Parma, Italy
    Addict Biol 10:275-81. 2005
    ..Our findings suggest that the 9-repeat allele of the DAT polymorphism confers increased susceptibility to antisocial - violent behaviour and aggressiveness, rather than drug dependence per se in heroin-dependent males...
  12. ncbi request reprint MIG1-dependent and MIG1-independent regulation of GAL gene expression in Saccharomyces cerevisiae: role of Imp2p
    Adriana Alberti
    Dipartimento di Genetica Antropologia Evoluzione, Universita degli Studi di Parma, Parco Area delle Scienze 11A, 43100 Parma, Italy
    Yeast 20:1085-96. 2003
    ..The results suggest a major role of Imp2 in a GAL6-independent pathway...
  13. pmc Infantile encephalopathy and defective mitochondrial DNA translation in patients with mutations of mitochondrial elongation factors EFG1 and EFTu
    Lucia Valente
    Pierfranco and Luisa Mariani Center for Research on Children s Mitochondrial Disorders, Division of Molecular Neurogenetics, National Neurological Institute Carlo Besta, Milano, Italy
    Am J Hum Genet 80:44-58. 2007
    ....