P Devoto

Summary

Affiliation: University of Cagliari
Country: Italy

Publications

  1. doi request reprint Disulfiram stimulates dopamine release from noradrenergic terminals and potentiates cocaine-induced dopamine release in the prefrontal cortex
    Paola Devoto
    Department of Neuroscience, University of Cagliari, Monserrato, Italy
    Psychopharmacology (Berl) 219:1153-64. 2012
  2. doi request reprint 6-Hydroxydopamine lesion in the ventral tegmental area fails to reduce extracellular dopamine in the cerebral cortex
    Paola Devoto
    B B Brodie Department of Neuroscience, University of Cagliari, Cagliari, Italy
    J Neurosci Res 86:1647-58. 2008
  3. pmc Co-release of noradrenaline and dopamine in the cerebral cortex elicited by single train and repeated train stimulation of the locus coeruleus
    Paola Devoto
    Department of Neuroscience B B Brodie University of Cagliari, Italy
    BMC Neurosci 6:31. 2005
  4. ncbi request reprint Stimulation of the locus coeruleus elicits noradrenaline and dopamine release in the medial prefrontal and parietal cortex
    Paola Devoto
    B B Brodie Department of Neuroscience, University of Cagliari, Cagliari, Italy
    J Neurochem 92:368-74. 2005
  5. ncbi request reprint Mirtazapine-induced corelease of dopamine and noradrenaline from noradrenergic neurons in the medial prefrontal and occipital cortex
    Paola Devoto
    B B Brodie Department of Neuroscience, University of Cagliari, SS 554 Km 4, 5, 09042 Monserrato CA, Italy
    Eur J Pharmacol 487:105-11. 2004
  6. ncbi request reprint Alpha2-adrenoceptor mediated co-release of dopamine and noradrenaline from noradrenergic neurons in the cerebral cortex
    Paola Devoto
    B B Brodie Department of Neuroscience Center of Excellence Neurobiology of Addiction, University of Cagliari, Italy
    J Neurochem 88:1003-9. 2004
  7. ncbi request reprint Origin of extracellular dopamine from dopamine and noradrenaline neurons in the medial prefrontal and occipital cortex
    Paola Devoto
    B B Brodie Department of Neuroscience, University of Cagliari, Monserrato, Italy
    Synapse 50:200-5. 2003
  8. ncbi request reprint Co-release of noradrenaline and dopamine from noradrenergic neurons in the cerebral cortex induced by clozapine, the prototype atypical antipsychotic
    Paola Devoto
    B B Brodie Department of Neuroscience, University of Cagliari, Cittadella Universitaria, SS 554 Km 4 500, 09042, Monserrato, Italy
    Psychopharmacology (Berl) 167:79-84. 2003
  9. ncbi request reprint Co-release of noradrenaline and dopamine in the prefrontal cortex after acute morphine and during morphine withdrawal
    Paola Devoto
    Dipartimento di Neuroscienze, Cittadella Universitaria, SS 554, Km 4, 5, 09042 Monserrato CA, Italy
    Psychopharmacology (Berl) 160:220-4. 2002
  10. ncbi request reprint Modulation of the effects of alcohol on driving-related psychomotor skills by chronic exposure to cannabis
    A Wright
    School of Psychology, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Psychopharmacology (Berl) 160:213-9. 2002

Detail Information

Publications16

  1. doi request reprint Disulfiram stimulates dopamine release from noradrenergic terminals and potentiates cocaine-induced dopamine release in the prefrontal cortex
    Paola Devoto
    Department of Neuroscience, University of Cagliari, Monserrato, Italy
    Psychopharmacology (Berl) 219:1153-64. 2012
    ..Disulfiram efficacy in treatment of cocaine addiction is attributed to the inhibition of dopamine-β-hydroxylase and reduction in brain noradrenaline (NA)/dopamine (DA) ratio...
  2. doi request reprint 6-Hydroxydopamine lesion in the ventral tegmental area fails to reduce extracellular dopamine in the cerebral cortex
    Paola Devoto
    B B Brodie Department of Neuroscience, University of Cagliari, Cagliari, Italy
    J Neurosci Res 86:1647-58. 2008
    ..The results strongly support the hypothesis that the majority of extracellular dopamine in the cortex, unlike that in the nucleus accumbens, originates from noradrenergic terminals...
  3. pmc Co-release of noradrenaline and dopamine in the cerebral cortex elicited by single train and repeated train stimulation of the locus coeruleus
    Paola Devoto
    Department of Neuroscience B B Brodie University of Cagliari, Italy
    BMC Neurosci 6:31. 2005
    ..To rule out possible stressful effects of electrical stimulation, experiments were performed on chloral hydrate anaesthetised rats...
  4. ncbi request reprint Stimulation of the locus coeruleus elicits noradrenaline and dopamine release in the medial prefrontal and parietal cortex
    Paola Devoto
    B B Brodie Department of Neuroscience, University of Cagliari, Cagliari, Italy
    J Neurochem 92:368-74. 2005
    ..These results indicate that electrical stimulation-induced increase of dopamine is a nerve impulse exocytotic process and suggest that cortical dopamine and noradrenaline may be coreleased from noradrenergic terminals...
  5. ncbi request reprint Mirtazapine-induced corelease of dopamine and noradrenaline from noradrenergic neurons in the medial prefrontal and occipital cortex
    Paola Devoto
    B B Brodie Department of Neuroscience, University of Cagliari, SS 554 Km 4, 5, 09042 Monserrato CA, Italy
    Eur J Pharmacol 487:105-11. 2004
    ..The results suggest that mirtazapine by inhibiting alpha(2)-adrenoceptors produces a corelease of noradrenaline and dopamine from noradrenergic terminals in the cerebral cortex...
  6. ncbi request reprint Alpha2-adrenoceptor mediated co-release of dopamine and noradrenaline from noradrenergic neurons in the cerebral cortex
    Paola Devoto
    B B Brodie Department of Neuroscience Center of Excellence Neurobiology of Addiction, University of Cagliari, Italy
    J Neurochem 88:1003-9. 2004
    ..The results support the hypothesis that most extracellular DA in the cortex is co-released with NA from noradrenergic terminals, such co-release being primarily controlled by alpha2-adrenoceptors...
  7. ncbi request reprint Origin of extracellular dopamine from dopamine and noradrenaline neurons in the medial prefrontal and occipital cortex
    Paola Devoto
    B B Brodie Department of Neuroscience, University of Cagliari, Monserrato, Italy
    Synapse 50:200-5. 2003
    ....
  8. ncbi request reprint Co-release of noradrenaline and dopamine from noradrenergic neurons in the cerebral cortex induced by clozapine, the prototype atypical antipsychotic
    Paola Devoto
    B B Brodie Department of Neuroscience, University of Cagliari, Cittadella Universitaria, SS 554 Km 4 500, 09042, Monserrato, Italy
    Psychopharmacology (Berl) 167:79-84. 2003
    ..A recent study of ours suggested that extracellular DA in the PFC originates not only from dopaminergic but also from noradrenergic terminals, its release being controlled by alpha(2)-adrenoceptors...
  9. ncbi request reprint Co-release of noradrenaline and dopamine in the prefrontal cortex after acute morphine and during morphine withdrawal
    Paola Devoto
    Dipartimento di Neuroscienze, Cittadella Universitaria, SS 554, Km 4, 5, 09042 Monserrato CA, Italy
    Psychopharmacology (Berl) 160:220-4. 2002
    ..In contrast, extracellular DA in the prefrontal cortex (PFC) is not modified by acute morphine and is markedly increased during abstinence syndrome...
  10. ncbi request reprint Modulation of the effects of alcohol on driving-related psychomotor skills by chronic exposure to cannabis
    A Wright
    School of Psychology, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Psychopharmacology (Berl) 160:213-9. 2002
    ....
  11. ncbi request reprint Evidence for co-release of noradrenaline and dopamine from noradrenergic neurons in the cerebral cortex
    P Devoto
    Department of Neuroscience BB Brodie, University of Cagliari, Via Porcell 4, I 09124 Cagliari, Italy
    Mol Psychiatry 6:657-64. 2001
    ..The co-release of NA and DA seems to be controlled by alpha(2)-receptors located on NA nerve terminals...
  12. ncbi request reprint Behavioural sensitization of mesolimbic dopamine D2 receptors in chronic fluoxetine-treated rats
    M Collu
    Department of Pharmacological Sciences, University of Sassari, Italy
    Eur J Pharmacol 322:123-7. 1997
    ..These results suggest that fluoxetine, as well as classical antidepressants, sensitize postsynaptic dopamine D2/D3 receptors in the mesolimbic system...
  13. ncbi request reprint Delta(9)-tetrahydrocannabinol decreases extracellular GABA and increases extracellular glutamate and dopamine levels in the rat prefrontal cortex: an in vivo microdialysis study
    Marco Pistis
    BB Brodie Department of Neuroscience, University of Cagliari, Cittadella Universitaria SS 554, 09042 Monserrato CA, Italy
    Brain Res 948:155-8. 2002
    ..These results suggest that delta(9)-THC disrupt the normal interplay between neurotransmitters in this area and may bear relevance in understanding neuronal mechanisms underlying cannabinoid-induced cognitive deficits...
  14. ncbi request reprint Lead intoxication during intrauterine life and lactation but not during adulthood reduces nucleus accumbens dopamine release as studied by brain microdialysis
    P Devoto
    B.B. Brodie' Department of Neuroscience, Center for Neuropharmacology, University of Cagliari, via Porcell, 09124-I, Cagliari, Italy
    Toxicol Lett 121:199-206. 2001
    ..These data indicate a preferential impairment of NAC DA synthesis and/or release in rats exposed to Pb acetate during their intrauterine life...
  15. doi request reprint Antipsychotic-like properties of 5-alpha-reductase inhibitors
    Marco Bortolato
    Department of Neuroscience Bernard B Brodie, University of Cagliari, Monserrato, Cagliari, Italy
    Neuropsychopharmacology 33:3146-56. 2008
    ..p.) induced no catalepsy in either the bar test or the paw test. Our results suggest that 5AR inhibitors elicit antipsychotic-like effects in animals and may be proposed as a putative novel target in the management of psychotic disorders...
  16. ncbi request reprint The control of responsiveness in ADHD by catecholamines: evidence for dopaminergic, noradrenergic and interactive roles
    Robert D Oades
    Clinic for Child and Adolescent Psychiatry, University of Duisburg Essen, Germany
    Dev Sci 8:122-31. 2005
    ..Recent insights into the previously underestimated role of the NA system in the control of mesocortical DA function, and the frontal role in processing information are elaborated...