Giuseppe Derosa

Summary

Affiliation: University of Pavia
Country: Italy

Publications

  1. ncbi request reprint Peroxisome proliferator-activated receptor-γ (PPAR-γ) agonists on glycemic control, lipid profile and cardiovascular risk
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Curr Mol Pharmacol 5:272-81. 2012
  2. doi request reprint Different aspects of sartan + calcium antagonist association compared to the single therapy on inflammation and metabolic parameters in hypertensive patients
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Fondazione IRCCS Policlinico S Matteo, P le C Golgi 2, 27100, Pavia, Italy
    Inflammation 37:154-62. 2014
  3. ncbi request reprint Alkaloids in the nature: pharmacological applications in clinical practice of berberine and mate tea
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia and Fondazione IRCCS Policlinico S Matteo, Pavia, Italy
    Curr Top Med Chem 14:200-6. 2014
  4. doi request reprint Berberis aristata/Silybum marianum fixed combination on lipid profile and insulin secretion in dyslipidemic patients
    Giuseppe Derosa
    University of Pavia, Department of Internal Medicine and Therapeutics, Fondazione IRCCS Policlinico S Matteo, P le C Golgi, 2 Pavia, 27100, Italy 39 0382 526217 39 0382 526259
    Expert Opin Biol Ther 13:1495-506. 2013
  5. doi request reprint Results from a 12 months, randomized, clinical trial comparing an olmesartan/amlodipine single pill combination to olmesartan and amlodipine monotherapies on blood pressure and inflammation
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy Center for the Study of Endocrine Metabolic Pathophysiology and Clinical Research, University of Pavia, Pavia, Italy Electronic address
    Eur J Pharm Sci 51:26-33. 2014
  6. doi request reprint Effects of canrenone in patients with metabolic syndrome
    Giuseppe Derosa
    University of Pavia, Department of Internal Medicine and Therapeutics, Fondazione IRCCS Policlinico S Matteo, P le C Golgi, 2 27100 Pavia, Italy 39 0382 526217 39 0382 526259
    Expert Opin Pharmacother 14:2161-9. 2013
  7. doi request reprint A comparison between sitagliptin or glibenclamide in addition to metformin + pioglitazone on glycaemic control and β-cell function: the triple oral therapy
    G Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Diabet Med 30:846-54. 2013
  8. doi request reprint Adipocytokine levels in obese and non-obese subjects: an observational study
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, P le C Golgi, 2 27100 Pavia, Italy
    Inflammation 36:914-20. 2013
  9. doi request reprint Exenatide plus metformin compared with metformin alone on β-cell function in patients with Type 2 diabetes
    G Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Diabet Med 29:1515-23. 2012
  10. doi request reprint Effects of berberine on lipid profile in subjects with low cardiovascular risk
    Giuseppe Derosa
    University of Pavia, Department of Internal Medicine and Therapeutics, Fondazione IRCCS Policlinico S Matteo, P le C Golgi, 2 27100 Pavia, Italy
    Expert Opin Biol Ther 13:475-82. 2013

Detail Information

Publications138 found, 100 shown here

  1. ncbi request reprint Peroxisome proliferator-activated receptor-γ (PPAR-γ) agonists on glycemic control, lipid profile and cardiovascular risk
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Curr Mol Pharmacol 5:272-81. 2012
    ..This review discusses the safety and effectiveness of pioglitazone in the clinical practice for the treatment of type 2 diabetes mellitus...
  2. doi request reprint Different aspects of sartan + calcium antagonist association compared to the single therapy on inflammation and metabolic parameters in hypertensive patients
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Fondazione IRCCS Policlinico S Matteo, P le C Golgi 2, 27100, Pavia, Italy
    Inflammation 37:154-62. 2014
    ....
  3. ncbi request reprint Alkaloids in the nature: pharmacological applications in clinical practice of berberine and mate tea
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia and Fondazione IRCCS Policlinico S Matteo, Pavia, Italy
    Curr Top Med Chem 14:200-6. 2014
    ..On the other hand, mate plant has reported to have high antioxidant potential, including an inhibitory ability against plasma and LDL oxidation...
  4. doi request reprint Berberis aristata/Silybum marianum fixed combination on lipid profile and insulin secretion in dyslipidemic patients
    Giuseppe Derosa
    University of Pavia, Department of Internal Medicine and Therapeutics, Fondazione IRCCS Policlinico S Matteo, P le C Golgi, 2 Pavia, 27100, Italy 39 0382 526217 39 0382 526259
    Expert Opin Biol Ther 13:1495-506. 2013
    ..Relatively large number of dietary supplements and nutraceuticals have been studied for their supposed or demonstrated ability to reduce cholesterolemia in humans...
  5. doi request reprint Results from a 12 months, randomized, clinical trial comparing an olmesartan/amlodipine single pill combination to olmesartan and amlodipine monotherapies on blood pressure and inflammation
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy Center for the Study of Endocrine Metabolic Pathophysiology and Clinical Research, University of Pavia, Pavia, Italy Electronic address
    Eur J Pharm Sci 51:26-33. 2014
    ..The aim of this study was to evaluate the effects of a fixed-dose olmesartan/amlodipine combination on blood pressure control, lipid profile, insulin sensitivity, and inflammation compared to singles monotherapies...
  6. doi request reprint Effects of canrenone in patients with metabolic syndrome
    Giuseppe Derosa
    University of Pavia, Department of Internal Medicine and Therapeutics, Fondazione IRCCS Policlinico S Matteo, P le C Golgi, 2 27100 Pavia, Italy 39 0382 526217 39 0382 526259
    Expert Opin Pharmacother 14:2161-9. 2013
    ..Metabolic syndrome is becoming a common disease due to a rise in obesity rates among adults...
  7. doi request reprint A comparison between sitagliptin or glibenclamide in addition to metformin + pioglitazone on glycaemic control and β-cell function: the triple oral therapy
    G Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Diabet Med 30:846-54. 2013
    ..To evaluate which triple oral therapy between metformin + pioglitazone + sitagliptin and metformin + pioglitazone + glibenclamide can be more useful in improving glycaemic control and should be preferred in clinical practice...
  8. doi request reprint Adipocytokine levels in obese and non-obese subjects: an observational study
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, P le C Golgi, 2 27100 Pavia, Italy
    Inflammation 36:914-20. 2013
    ..We confirmed obese subjects' predisposition to develop dysmetabolic disease and hormonal dysfunctions. ..
  9. doi request reprint Exenatide plus metformin compared with metformin alone on β-cell function in patients with Type 2 diabetes
    G Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Diabet Med 29:1515-23. 2012
    ..To quantify how much exenatide added to metformin improves β-cell function, and to evaluate the impact on glycaemic control, insulin resistance and inflammation compared with metformin alone...
  10. doi request reprint Effects of berberine on lipid profile in subjects with low cardiovascular risk
    Giuseppe Derosa
    University of Pavia, Department of Internal Medicine and Therapeutics, Fondazione IRCCS Policlinico S Matteo, P le C Golgi, 2 27100 Pavia, Italy
    Expert Opin Biol Ther 13:475-82. 2013
    ..To evaluate the efficacy as antihypercholesterolemic agent of berberine in patients with low cardiovascular risk...
  11. doi request reprint Effects of an olmesartan/amlodipine fixed dose on blood pressure control, some adipocytokines and interleukins levels compared with olmesartan or amlodipine monotherapies
    G Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    J Clin Pharm Ther 38:48-55. 2013
    ..To evaluate the effects of an olmesartan/amlodipine single pill combination compared with olmesartan or amlodipine monotherapies on blood pressure control, lipid profile, insulin sensitivity and some adipocytokines levels...
  12. doi request reprint Effects of n-3 PUFAs on postprandial variation of metalloproteinases, and inflammatory and insulin resistance parameters in dyslipidemic patients: evaluation with euglycemic clamp and oral fat load
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    J Clin Lipidol 6:553-64. 2012
    ..The oral fat load (OFL) is considered as one of the most accurate models of postprandial lipoprotein metabolism and it has been widely used to evaluate the postprandial fat load effect on single markers of inflammation...
  13. doi request reprint Vildagliptin action on some adipocytokine levels in type 2 diabetic patients: a 12-month, placebo-controlled study
    Giuseppe Derosa
    University of Pavia, Department of Internal Medicine and Therapeutics, Fondazione IRCCS Policlinico, S Matteo, Pavia, P le C Golgi, 2 27100 Pavia, Italy
    Expert Opin Pharmacother 13:2581-91. 2012
    ..To evaluate the action of vildagliptin + metformin on some adipocytokine levels, glycemic control, and β-cell function in type 2 diabetic patients...
  14. ncbi request reprint Evaluation of emerging biomarkers in cardiovascular risk stratification of hypertensive patients: a 2-year study
    G Derosa
    Department of Internal Medicine and Therapeutics, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy
    Curr Med Res Opin 28:1435-45. 2012
    ....
  15. doi request reprint A randomized, double-blind, placebo-controlled trial evaluating sitagliptin action on insulin resistance parameters and β-cell function
    Giuseppe Derosa
    University of Pavia, Department of Internal Medicine and Therapeutics, Fondazione IRCCS Policlinico S Matteo, Pavia, Italy
    Expert Opin Pharmacother 13:2433-42. 2012
    ..To evaluate the impact on glycemic control, insulin secretion and on insulin resistance of a sitagliptin + metformin combination compared to metformin monotherapy in type 2 diabetic, naïve to treatment, patients...
  16. doi request reprint Effects of a combination of sitagliptin plus metformin vs metformin monotherapy on glycemic control, β-cell function and insulin resistance in type 2 diabetic patients
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Diabetes Res Clin Pract 98:51-60. 2012
    ..To evaluate the impact on glycemic control, insulin resistance, and insulin secretion of sitagliptin+metformin compared to metformin in type 2 diabetic patients...
  17. ncbi request reprint Glyco-metabolic profile among type 2 diabetic patients with erectile dysfunction
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, Fondazione IRCCS Policlinico S Matteo, University of Pavia, Pavia 27100, Italy
    Endocr J 59:611-9. 2012
    ..The prevalence of ED in Italian type 2 diabetic males with mean age of 62 years is about 56% and it is linked to higher levels of FPI, but lower levels of HbA(1c), free testosterone and dihydrotestosterone...
  18. doi request reprint Efficacy and safety profile evaluation of acarbose alone and in association with other antidiabetic drugs: a systematic review
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Fondazione IRCCS Policlinico S Matteo, Pavia, Italy
    Clin Ther 34:1221-36. 2012
    ..Epidemiologic studies have revealed that postprandial hyperglycemia significantly contributes to high glycated hemoglobin concentrations and could be linked to the development of chronic diabetic complications...
  19. ncbi request reprint GLP-1 agonists exenatide and liraglutide: a review about their safety and efficacy
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Fondazione IRCCS Policlinico S Matteo, Pavia, Italy
    Curr Clin Pharmacol 7:214-28. 2012
    ..GLP-1 receptor agonists should be considered also in patients in therapy with metformin and another agent, such as a sulfonylurea, because of the minor risk of developing hypoglycemia and the positive effect on body weight...
  20. doi request reprint Vildagliptin added to metformin on β-cell function after a euglycemic hyperinsulinemic and hyperglycemic clamp in type 2 diabetes patients
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Diabetes Technol Ther 14:475-84. 2012
    ..This study evaluated the effect of vildagliptin + metformin on glycemic control and β-cell function in type 2 diabetes patients...
  21. doi request reprint Nifedipine and telmisartan for the treatment of hypertension: the TALENT study
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Fondazione IRCCS Policlinico S Matteo, P le C Golgi, 2 27100 Pavia, Italy
    Expert Rev Cardiovasc Ther 9:1499-503. 2011
    ..The study shows that combination treatment with nifedipine GITS and telmisartan provides a greater and earlier blood pressure reduction than the combination components in monotherapy...
  22. doi request reprint Berberine on metabolic and cardiovascular risk factors: an analysis from preclinical evidences to clinical trials
    Giuseppe Derosa
    University of Pavia, Department of Internal Medicine and Therapeutics, Fondazione IRCCS Policlinico S Matteo, P le C Golgi, 2 27100 Pavia, Italy
    Expert Opin Biol Ther 12:1113-24. 2012
    ..Recent studies have suggested that the natural alkaloid berberine could have pharmacological activities potentially useful in diabetes and hypercholesterolemia management...
  23. doi request reprint Dipeptidyl peptidase-4 inhibitors: 3 years of experience
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Foundation IRCCS Policlinico S Matteo, Piazzale C Golgi 2, Pavia, Italy
    Diabetes Technol Ther 14:350-64. 2012
    ..They also have positive effects on β-cell function, and they have neutral effects on body weight. Furthermore, DPP-4 inhibitors prevent the risk of hypoglycemia posed by sulfonylureas...
  24. doi request reprint Anti-obesity drugs: a review about their effects and their safety
    Giuseppe Derosa
    University of Pavia, Fondazione IRCCS Policlinico S Matteo, Department of Internal Medicine and Therapeutics, P le C Golgi, 2 27100 Pavia, Italy
    Expert Opin Drug Saf 11:459-71. 2012
    ..Amphetamines, rimonabant and sibutramine licenses as anti-obesity drugs have been withdrawn because of their adverse effects. In fact, orlistat is the only available long-term treatment for obesity...
  25. doi request reprint Effects of 1-year orlistat treatment compared to placebo on insulin resistance parameters in patients with type 2 diabetes
    G Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    J Clin Pharm Ther 37:187-95. 2012
    ..The aim of this study was to compare the effects of orlistat and placebo on body weight, glycaemic and lipid profile and insulin resistance in patients with type 2 diabetes...
  26. doi request reprint Differential effects of candesartan and olmesartan on adipose tissue activity biomarkers in type II diabetic hypertensive patients
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Hypertens Res 33:790-5. 2010
    ..Both treatments resulted in a similar reduction in Hs-CRP. Although both therapies resulted in similar reductions in blood pressure, candesartan therapy was more effective than olmesartan therapy in improving insulin sensitivity...
  27. ncbi request reprint Irbesartan and hydrochlorothiazide association in the treatment of hypertension
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    Curr Vasc Pharmacol 7:120-36. 2009
    ..Ongoing trials about irbesartan and its combination with diuretics may provide necessary data to interpret the value of this association among others...
  28. doi request reprint Direct comparison among oral hypoglycemic agents and their association with insulin resistance evaluated by euglycemic hyperinsulinemic clamp: the 60's study
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Fondazione IRCCS Policlinico S Matteo, 2 27100 Pavia, Italy
    Metabolism 58:1059-66. 2009
    ..Pioglitazone-metformin-based therapeutic control is associated with the most quantitatively relevant improvement in insulin resistance-related parameters, whereas the sulfonylurea-metformin-including protocol has less relevant effects...
  29. doi request reprint Efficacy and tolerability of pioglitazone in patients with type 2 diabetes mellitus: comparison with other oral antihyperglycaemic agents
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Drugs 70:1945-61. 2010
    ..In conclusion, pioglitazone is an effective oral antihyperglycaemic agent with additional cardiovascular and lipid benefits that allows for the successful management of patients with T2DM...
  30. ncbi request reprint Effects of long chain omega-3 fatty acids on metalloproteinases and their inhibitors in combined dyslipidemia patients
    G Derosa
    University of Pavia, Department of Internal Medicine and Therapeutics, P le C Golgi, 2 27100, Pavia, Italy
    Expert Opin Pharmacother 10:1239-47. 2009
    ..Furthermore, lowers levels of MMP-2, MMP-9 and their tissue inhibitors are obtained with n-3 PUFAs compared to placebo...
  31. ncbi request reprint Orlistat and L-carnitine compared to orlistat alone on insulin resistance in obese diabetic patients
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Endocr J 57:777-86. 2010
    ....
  32. doi request reprint Fenofibrate, simvastatin and their combination in the management of dyslipidaemia in type 2 diabetic patients
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Fondazione IRCCS Policlinico S Matteo, 2 27100 Pavia, Italy
    Curr Med Res Opin 25:1973-83. 2009
    ..We evaluated lipids, glycaemic, haemostatic, and inflammatory variables at baseline, and after 6 and 12 months...
  33. ncbi request reprint Effects of insulin therapy with continuous subcutaneous insulin infusion (CSII) in diabetic patients: comparison with multi-daily insulin injections therapy (MDI)
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Endocr J 56:571-8. 2009
    ..CSII therapy allows a faster and better achievement of the therapeutic target and also gives an improvement of the lipid profile...
  34. ncbi request reprint Evaluation of metalloproteinase 2 and 9 levels and their inhibitors in combined dyslipidemia
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Clin Invest Med 32:E124-32. 2009
    ..To evaluate the distribution of matrix metalloproteinase-2 (MMP-2), matrix metalloproteinase-9 (MMP-9), and their specific inhibitors in a sample of patients affected by mild dyslipidemia but not yet treated with antihyperlipidemic drugs...
  35. doi request reprint Oral fat load effects on inflammation and endothelial stress markers in healthy subjects
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Fondazione IRCCS, Policlinico San Matteo, P C Golgi 2, 27100 Pavia, Italy
    Heart Vessels 24:204-10. 2009
    ..05 vs 0), and +28.57% at 12 h. We observed that the OFL induces a complex and massive systemic inflammatory response that includes IL-6, TNF-alpha, hsCRP, and cell adhesion molecules, even before Tg significantly rises...
  36. ncbi request reprint Metabolic effect of repaglinide or acarbose when added to a double oral antidiabetic treatment with sulphonylureas and metformin: a double-blind, cross-over, clinical trial
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Curr Med Res Opin 25:607-15. 2009
    ..The second endpoint was to evaluate which of these two treatment is more efficacious in the global management of glucose homeostasis in the enrolled patients...
  37. doi request reprint Sibutramine effect on metabolic control of obese patients with type 2 diabetes mellitus treated with pioglitazone
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, 19 27100 Pavia, Italy
    Metabolism 57:1552-7. 2008
    ..Sibutramine appears to be a tolerable and efficacious drug when added to pioglitazone for the global management of obese diabetic patients...
  38. ncbi request reprint Pioglitazone and rosiglitazone: effects of treatment with a thiazolidinedione on lipids and non conventional cardiovascular risk factors
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Piazzale C Golgi 2, Pavia, Italy
    Curr Clin Pharmacol 3:77-84. 2008
    ....
  39. doi request reprint Comparison between orlistat plus l-carnitine and orlistat alone on inflammation parameters in obese diabetic patients
    Giuseppe Derosa
    Fondazione IRCCS Policlinico S Matteo, Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, P le C Golgi, 2 27100 Pavia, Italy
    Fundam Clin Pharmacol 25:642-51. 2011
    ....
  40. doi request reprint Matrix metalloproteinase-2 and -9 levels in obese patients
    G Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    Endothelium 15:219-24. 2008
    ..MMP-2 and MMP-9 levels were significantly higher in obese group (p< .0001). Plasma levels of MMP-2 and MMP-9 are increased in obese patients which may reflect abnormal ECM metabolism...
  41. ncbi request reprint Effects of one year treatment of sibutramine on insulin resistance parameters in type 2 diabetic patients
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, P le C Golgi, 2 27100 Pavia, Italy
    J Pharm Pharm Sci 13:378-90. 2010
    ..Comparison of the effects of one year treatment with sibutramine compared to placebo on insulin resistance parameters, body weight, glycemic control, and lipid profile, in type 2 diabetic patients...
  42. ncbi request reprint Efficacy and safety of ezetimibe/simvastatin association on non-diabetic and diabetic patients with polygenic hypercholesterolemia or combined hyperlipidemia and previously intolerant to standard statin treatment
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    J Clin Pharm Ther 34:267-76. 2009
    ....
  43. doi request reprint Thiazolidinediones plus metformin association on body weight in patients with type 2 diabetes
    G Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, 27100 Pavia, Italy
    Diabetes Res Clin Pract 91:265-70. 2011
    ..For these reasons we can safely say that thiazolidinediones in combination with metformin are effective and well tolerated in patients with type 2 diabetes...
  44. doi request reprint Effects of thiazolidinediones and sulfonylureas in patients with diabetes
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Fondazione IRCCS Policlinico S Matteo, Pavia, Italy
    Diabetes Technol Ther 12:491-501. 2010
    ..We also evaluated the effects of these two drugs on beta-cell function, insulin resistance, and inflammatory markers, also recording the frequency of adverse events such as edema and heart failure...
  45. doi request reprint Effects of combination of sibutramine and L-carnitine compared with sibutramine monotherapy on inflammatory parameters in diabetic patients
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, 27100 Pavia, Italy
    Metabolism 60:421-9. 2011
    ..Sibutramine plus L-carnitine gave a better and faster improvement of all the analyzed parameters compared with sibutramine alone without giving any severe adverse effect...
  46. doi request reprint Effects of a standardized oral fat load on vascular remodelling markers in healthy subjects
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    Microvasc Res 80:110-5. 2010
    ..We observed that nitrites/nitrates and ADP significantly decreased and MMP-2 and MMP-9 significantly increased after a standardized OFL. Other studies need to confirm the direct acute effects of post-prandial lipemia on vascular damage...
  47. ncbi request reprint Sibutramine and L-carnitine compared to sibutramine alone on insulin resistance in diabetic patients
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Intern Med 49:1717-25. 2010
    ..To evaluate the effects of one year of treatment with sibutramine plus L-carnitine compared to sibutramine on body weight, glycemic control, and insulin resistance state in type 2 diabetic patients...
  48. doi request reprint Effects of amlodipine plus atorvastatin association in hypertensive hypercholesterolemic patients
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Fondazione IRCCS Policlinico S Matteo, Pavia, Italy
    Expert Rev Cardiovasc Ther 8:835-43. 2010
    ..For these reasons, the combination of amlodipine plus atorvastatin could be the treatment of choice in hypertensive and hypercholesterolemic patients...
  49. doi request reprint Effects of one year treatment of vildagliptin added to pioglitazone or glimepiride in poorly controlled type 2 diabetic patients
    G Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Horm Metab Res 42:663-9. 2010
    ..Pioglitazone plus vildagliptin were found to be more effective in preserving beta-cell function, and in reducing insulin resistance, and inflammatory state parameters...
  50. doi request reprint Exenatide versus glibenclamide in patients with diabetes
    G Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Italy
    Diabetes Technol Ther 12:233-40. 2010
    ..The aim of our study was to evaluate the effects of exenatide compared to glibenclamide on body weight, glycemic control, beta-cell function, insulin resistance, and inflammatory state in patients with diabetes...
  51. doi request reprint Comparison of orlistat treatment and placebo in obese type 2 diabetic patients
    Giuseppe Derosa
    University of Pavia, Department of Internal Medicine and Therapeutics, 27100 Pavia, Italy
    Expert Opin Pharmacother 11:1971-82. 2010
    ..To evaluate the effects of 1-year treatment with orlistat compared with placebo on different inflammatory parameters in type 2 obese diabetic patients...
  52. doi request reprint Modification of vascular and inflammation biomarkers after OGTT in overweight healthy and diabetic subjects
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Fondazione IRCCS Policlinico S Matteo, Pavia, P le C Golgi, 2 27100 Pavia, Italy
    Microvasc Res 79:144-9. 2010
    ..MMP-9 levels were higher in D group than in H group during OGTT. Postprandial glycemia induces an acute increase in biomarkers of vascular remodelling...
  53. doi request reprint Effect of pioglitazone and acarbose on endothelial inflammation biomarkers during oral glucose tolerance test in diabetic patients treated with sulphonylureas and metformin
    G Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    J Clin Pharm Ther 35:565-79. 2010
    ..Some of these factors appear to be particularly evident during the post-prandial phases and to be related to peak plasma glucose level...
  54. doi request reprint Candesartan effect on inflammation in hypertension
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Fondazione IRCCS Policlinico S Matteo, Pavia, Italy
    Hypertens Res 33:209-13. 2010
    ..We observed that candesartan treatment attenuated the inflammatory answer in both groups of patients, even if more efficiently in nondiabetic ones...
  55. doi request reprint Effects of sitagliptin or metformin added to pioglitazone monotherapy in poorly controlled type 2 diabetes mellitus patients
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Metabolism 59:887-95. 2010
    ....
  56. doi request reprint Modulation of adipokines and vascular remodelling markers during OGTT with acarbose or pioglitazone treatment
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Fondazione IRCCS Policlinico S Matteo, P le C Golgi 2, 27100 Pavia, Italy
    Biomed Pharmacother 63:723-33. 2009
    ..Pioglitazone improves glucose metabolism and insulin-resistance compared to acarbose in type 2 diabetic patients already treated with metformin and sulphonilureas...
  57. doi request reprint Effects of pioglitazone and rosiglitazone combined with metformin on body weight in people with diabetes
    G Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Fondazione IRCCS, Policlinico S Matteo, 27100 Pavia, Italy
    Diabetes Obes Metab 11:1091-9. 2009
    ..We have undertaken a thorough literature search on Medline and Embase to evaluate the effects of thiazolidinediones plus metformin combination in people with diabetes on the body weight...
  58. doi request reprint Oral glucose tolerance test effects on endothelial inflammation markers in healthy subjects and diabetic patients
    G Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Fondazione IRCCS Policlinico S Matteo, P le C Golgi 2, 27100 Pavia, Italy
    Horm Metab Res 42:8-13. 2010
    ..Type 2 diabetics experienced, however, a more significant increase in TNF-alpha, and sE-selectin...
  59. doi request reprint Rosiglitazone therapy improves insulin resistance parameters in overweight and obese diabetic patients intolerant to metformin
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Arch Med Res 39:412-9. 2008
    ....
  60. doi request reprint Different actions of losartan and ramipril on adipose tissue activity and vascular remodeling biomarkers in hypertensive patients
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Fondazione IRCCS Policlinico S Matteo, Pavia, Italy
    Hypertens Res 34:145-51. 2011
    ....
  61. doi request reprint Variation of inflammatory parameters after sibutramine treatment compared to placebo in type 2 diabetic patients
    G Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia G Descovich Atherosclerosis Study Center, Department of Internal Medicine, Aging and Kidney diseases, University of Bologna, Bologna, Italy
    J Clin Pharm Ther 36:592-601. 2011
    ..Our objective was to evaluate the effects of 1-year treatment with sibutramine compared to placebo on body weight, glycaemic control, lipid profile, and inflammatory parameters in type 2 diabetic patients...
  62. ncbi request reprint Telmisartan and irbesartan therapy in type 2 diabetic patients treated with rosiglitazone: effects on insulin-resistance, leptin and tumor necrosis factor-alpha
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Hypertens Res 29:849-56. 2006
    ..These observed metabolic effects of different angiotensin type 1 receptor blockers could be relevant when choosing a therapy to correct metabolic derangement of patients affected by metabolic syndrome and diabetes...
  63. ncbi request reprint Evaluation of metalloproteinase 2 and 9 levels and their inhibitors in diabetic and healthy subjects
    G Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Fondazione IRCCS Policlinico S Matteo, Pavia, Piazzale C Golgi 2, 27100 Pavia, Italy
    Diabetes Metab 33:129-34. 2007
    ..To test this hypothesis, we measured the plasma levels of MMP-2, MMP-9, TIMP-1, and TIMP-2 in type 2 diabetic patients and in healthy subjects...
  64. ncbi request reprint Metabolic effects of pioglitazone and rosiglitazone in patients with diabetes and metabolic syndrome treated with metformin
    G Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, IRCCS Policlinico S Matteo, Pavia, Italy
    Intern Med J 37:79-86. 2007
    ....
  65. doi request reprint Pioglitazone compared to glibenclamide on lipid profile and inflammation markers in type 2 diabetic patients during an oral fat load
    G Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Horm Metab Res 43:505-12. 2011
    ..We can conclude that pioglitazone was better than glibenclamide in mitigating the variations of lipid components and inflammation parameters in type 2 diabetic patients...
  66. ncbi request reprint Synergistic effect of doxazosin and acarbose in improving metabolic control in patients with impaired glucose tolerance
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Clin Drug Investig 26:529-39. 2006
    ..The aim of this study was to evaluate if the expected improvement in glucose and lipid metabolism obtainable with doxazosin is or is not synergistic with standard antihyperglycaemic treatment using the alpha-glucosidase inhibitor acarbose...
  67. doi request reprint Drug safety evaluation of amlodipine
    Giuseppe Derosa
    University of Pavia, Department of Internal Medicine and Therapeutics, Fondazione IRCCS Policlinico S Matteo, P le C Golgi, 2 27100 Pavia, Italy
    Expert Opin Drug Saf 10:795-804. 2011
    ..7% in England to 81.3% in Spain demonstrating substantial unmet need in the effective treatment of arterial hypertension...
  68. doi request reprint Exenatide or glimepiride added to metformin on metabolic control and on insulin resistance in type 2 diabetic patients
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Eur J Pharmacol 666:251-6. 2011
    ..Furthermore, adiponectin increase, and tumor necrosis factor-α reduction seem to be related to weight loss obtained with exenatide...
  69. ncbi request reprint Prospects for the development of novel anti-hyperlipidemic drugs
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Italy
    Curr Opin Investig Drugs 7:826-33. 2006
    ....
  70. ncbi request reprint Metformin-pioglitazone and metformin-rosiglitazone effects on non-conventional cardiovascular risk factors plasma level in type 2 diabetic patients with metabolic syndrome
    G Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    J Clin Pharm Ther 31:375-83. 2006
    ....
  71. doi request reprint Pioglitazone is a valid alternative to rosiglitazone
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Italy
    Am J Cardiovasc Drugs 11:357-62. 2011
    ..This article focuses on the various steps that led to this important decision, and discusses a possible alternative for the treatment of patients receiving rosiglitazone...
  72. ncbi request reprint Metalloproteinase-2 and -9 in diabetic and nondiabetic subjects during acute coronary syndromes
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Fondazione IRCCS Policlinico S Matteo, Pavia, Italy
    Endothelium 14:45-51. 2007
    ..MMP-9, TIMP-1, and TIMP-2 plasma levels were increased in diabetic patients with ACSs, which may reflect abnormal extracellular matrix metabolism in diabetes during acute event...
  73. doi request reprint Acarbose on insulin resistance after an oral fat load: a double-blind, placebo controlled study
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Pavia, Italy
    J Diabetes Complications 25:258-66. 2011
    ..We evaluated the effects of acarbose on insulin resistance parameters in diabetic patients before and after a standardized oral fat load (OFL)...
  74. ncbi request reprint Metabolic effects of telmisartan and irbesartan in type 2 diabetic patients with metabolic syndrome treated with rosiglitazone
    G Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    J Clin Pharm Ther 32:261-8. 2007
    ..The aim of our study was to investigate the metabolic effects of telmisartan and irbesartan in diabetic subjects treated with rosiglitazone...
  75. ncbi request reprint Comparison between metalloproteinases-2 and -9 in healthy subjects, diabetics, and subjects with acute coronary syndrome
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Fondazione IRCCS Policlinico S Matteo, Pavia, Italy
    Heart Vessels 22:361-70. 2007
    ..In conclusion, MMP-2, MMP-9, TIMP-1, and TIMP-2 plasma levels were higher in diabetic, ACS, and DACS patients, which may reflect abnormal extracellular matrix metabolism in diabetes and in acute coronary syndrome...
  76. ncbi request reprint Effects of nateglinide and glibenclamide on prothrombotic factors in naïve type 2 diabetic patients treated with metformin: a 1-year, double-blind, randomized clinical trial
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Italy
    Intern Med 46:1837-46. 2007
    ..To evaluate the effect on coagulation and fibrinolysis parameters and on non-conventional cardiovascular risk factors of metformin plus nateglinide or glibenclamide in naïve type 2 diabetes patients...
  77. doi request reprint Acarbose actions on insulin resistance and inflammatory parameters during an oral fat load
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Eur J Pharmacol 651:240-50. 2011
    ..Acarbose was more effective than acarbose in reducing the post-OFL peaks of the various parameters included the inflammatory markers, after 7months of therapy...
  78. ncbi request reprint Metalloproteinases in diabetics and nondiabetics during acute coronary syndromes and after 3 months
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Endothelium 14:175-83. 2007
    ..MMPs and TIMP-1 and -2 plasma levels were alterated in nondiabetic and diabetic patients during ACS and after 3 months, which may reflect abnormal extracellular matrix metabolism in diabetes during and after acute event...
  79. ncbi request reprint Pioglitazone metabolic effect in metformin-intolerant obese patients treated with sibutramine
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Fondazione IRCCS Policlinico S Matteo, Pavia, Italy
    Intern Med 48:265-71. 2009
    ..We aimed to comparatively test the efficacy and tolerability of pioglitazone and sibutramine in metformin-intolerant obese type 2 diabetic patients treated with sibutramine...
  80. ncbi request reprint Metabolic and antihypertensive effects of moxonidine and moxonidine plus irbesartan in patients with type 2 diabetes mellitus and mild hypertension: a sequential, randomized, double-blind clinical trial
    Giuseppe Derosa
    Department o f Internal Medicine and Therapeutics, University of Pavia, Fondazione IRCCS Policlinico S Matteo, Pavia, Italy
    Clin Ther 29:602-10. 2007
    ..The autonomic nervous system plays an important part in the homeostasis of blood pressure (BP), and sympathetic overactivity may contribute to metabolic conditions such as glycemic intolerance or insulin resistance...
  81. ncbi request reprint Blood pressure control and inflammatory markers in type 2 diabetic patients treated with pioglitazone or rosiglitazone and metformin
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Fondazione IRCCS Policlinico S Matteo, Pavia, Italy
    Hypertens Res 30:387-94. 2007
    ....
  82. pmc Optimizing combination treatment in the management of type 2 diabetes
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Vasc Health Risk Manag 3:665-71. 2007
    ..The possible adverse effects derived from the association of different drug classes are also considered...
  83. ncbi request reprint Effects of amlodipine-atorvastatin combination on inflammation markers and insulin sensitivity in normocholesterolemic obese hypertensive patients
    Roberto Fogari
    Department of Internal Medicine and Therapeutics, Clinica Medica II, IRCCS Policlinico S Matteo, University of Pavia, Piazzale Golgi 19, 27100, Pavia, Italy
    Eur J Clin Pharmacol 62:817-22. 2006
    ..The objective of this study was to assess the effect of amlodipine-atorvastatin combination on plasma interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-alpha) and insulin sensitivity in normocholesterolemic obese hypertensive patients...
  84. ncbi request reprint Long-term effects of glimepiride or rosiglitazone in combination with metformin on blood pressure control in type 2 diabetic patients affected by the metabolic syndrome: a 12-month, double-blind, randomized clinical trial
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Clin Ther 27:1383-91. 2005
    ..Based on a literature search, few direct comparisons of different antihyperglycemic treatments on blood pressure have been reported...
  85. ncbi request reprint Effect of delapril/manidipine vs olmesartan/ hydrochlorothiazide combination on insulin sensitivity and fibrinogen in obese hypertensive patients
    Roberto Fogari
    Department of Internal Medicine and Therapeutics, Centro per l Ipertensione e la Fisiopatologia Cardiovascolare, University of Pavia, Italy
    Intern Med 47:361-6. 2008
    ..To compare the effect of delapril/manidipine vs olmesartan/hydrochlorothiazide (HCTZ) combination on insulin sensitivity and plasma fibrinogen in obese hypertensive patients...
  86. ncbi request reprint Effects of 1 year of treatment with pioglitazone or rosiglitazone added to glimepiride on lipoprotein (a) and homocysteine concentrations in patients with type 2 diabetes mellitus and metabolic syndrome: a multicenter, randomized, double-blind, controlled
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Clin Ther 28:679-88. 2006
    ....
  87. ncbi request reprint A comparison of the effects of pioglitazone and rosiglitazone combined with glimepiride on prothrombotic state in type 2 diabetic patients with the metabolic syndrome
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, P le C Golgi, 2 27100 Pavia, Italy
    Diabetes Res Clin Pract 69:5-13. 2005
    ..To compare the effects of glimepiride plus pioglitazone or plus rosiglitazone in diabetic patients with the metabolic syndrome on coagulation and fibrinolysis parameters...
  88. doi request reprint Effects of manidipine/delapril versus olmesartan/hydrochlorothiazide combination therapy in elderly hypertensive patients with type 2 diabetes mellitus
    Roberto Fogari
    Department of Internal Medicine and Therapeutics, Clinica Medica II Fondazione IRCCS Policlinico S Matteo, University of Pavia, Italy
    Hypertens Res 31:43-50. 2008
    ..However, manidipine/delapril offered some advantages in terms of the less-pronounced BP orthostatic changes and absence of metabolic adverse effects...
  89. ncbi request reprint Antithrombotic effects of rosiglitazone-metformin versus glimepiride-metformin combination therapy in patients with type 2 diabetes mellitus and metabolic syndrome
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Italy
    Pharmacotherapy 25:637-45. 2005
    ....
  90. ncbi request reprint Comparison of the effects of telmisartan and nifedipine gastrointestinal therapeutic system on blood pressure control, glucose metabolism, and the lipid profile in patients with type 2 diabetes mellitus and mild hypertension: a 12-month, randomized, doubl
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Clin Ther 26:1228-36. 2004
    ..Angiotensin receptor blockers (ARBs) provide effective blood pressure control. Whereas none of the ARBs appear to affect glucose homeostasis, some ARBs have been associated with a decrease in cholesterolemia...
  91. ncbi request reprint Effect of amlodipine-atorvastatin combination on fibrinolysis in hypertensive hypercholesterolemic patients with insulin resistance
    Roberto Fogari
    Department of Internal Medicine and Therapeutics, Clinica Medica II IRCCS Policlinico S Matteo, University of Pavia, Pavia, Italy
    Am J Hypertens 17:823-7. 2004
    ....
  92. ncbi request reprint Long-term effect of glimepiride and rosiglitazone on non-conventional cardiovascular risk factors in metformin-treated patients affected by metabolic syndrome: a randomized, double-blind clinical trial
    G Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    J Int Med Res 33:284-94. 2005
    ....
  93. doi request reprint Effect of a sequential training programme on inflammatory, prothrombotic and vascular remodelling biomarkers in hypertensive overweight patients with or without metabolic syndrome
    Arrigo F G Cicero
    Department of Internal Medicine, Aging and Kidney diseases, University of Bologna, Bologna, Italy
    Eur J Cardiovasc Prev Rehabil 16:698-704. 2009
    ..It is not known whether serum level of vascular remodelling parameters, such as matrix metalloproteinases could be modulated by physical activity and whether the eventual change could be influenced by metabolic syndrome (MS) diagnosis...
  94. ncbi request reprint Metabolic effects of pioglitazone and rosiglitazone in patients with diabetes and metabolic syndrome treated with glimepiride: a twelve-month, multicenter, double-blind, randomized, controlled, parallel-group trial
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Piazzale C Golgi 2, 27100 Pavia, Italy
    Clin Ther 26:744-54. 2004
    ..Glimepiride is approved as monotherapy and in combination with metformin or with insulin, whereas the combination of glimepiride with other antihyperglycemic drugs is under investigation...
  95. ncbi request reprint Randomized, double-blind, placebo-controlled comparison of the action of orlistat, fluvastatin, or both an anthropometric measurements, blood pressure, and lipid profile in obese patients with hypercholesterolemia prescribed a standardized diet
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Clin Ther 25:1107-22. 2003
    ....
  96. ncbi request reprint Matrix metalloproteinase-2, -9, and tissue inhibitor of metalloproteinase-1 in patients with hypertension
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Endothelium 13:227-31. 2006
    ..0001) and for TIMP-1 (p < .0001) in hypertensive patients. Plasma levels and activities of MMP-2, MMP-9, and TIMP-1 are increased in hypertensive patients, which may reflect abnormal ECM metabolism...
  97. doi request reprint Nateglinide and glibenclamide metabolic effects in naïve type 2 diabetic patients treated with metformin
    G Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    J Clin Pharm Ther 34:13-23. 2009
    ..The aim of the present study was to compare the effects of nateglinide plus metformin with glibenclamide plus metformin on glucose and lipid metabolism, and haemodynamic parameters in patients with type 2 diabetes mellitus...
  98. ncbi request reprint Effects of telmisartan compared with eprosartan on blood pressure control, glucose metabolism and lipid profile in hypertensive, type 2 diabetic patients: a randomized, double-blind, placebo-controlled 12-month study
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Italy
    Hypertens Res 27:457-64. 2004
    ....
  99. ncbi request reprint Thiazolidinedione effects on blood pressure in diabetic patients with metabolic syndrome treated with glimepiride
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, Italy
    Hypertens Res 28:917-24. 2005
    ....
  100. ncbi request reprint Comparison of fluvastatin + fenofibrate combination therapy and fluvastatin monotherapy in the treatment of combined hyperlipidemia, type 2 diabetes mellitus, and coronary heart disease: a 12-month, randomized, double-blind, controlled trial
    Giuseppe Derosa
    Department of Internal Medicine and Therapeutics, University of Pavia, P le C Golgi, 2 27100 Pavia, Italy
    Clin Ther 26:1599-607. 2004
    ..Diabetes risk is often complicated by a mixed hyperlipoproteinemia not sufficiently controlled by a single antihyperlipidemic drug; however, there are some concerns about the safety of combined statin and fibrate treatments...
  101. ncbi request reprint Effect of telmisartan-amlodipine combination at different doses on urinary albumin excretion in hypertensive diabetic patients with microalbuminuria
    Roberto Fogari
    Department of Internal Medicine and Therapeutics, Clinica Medica II IRCCS Policlinico S Matteo, University of Pavia, Pavia, Italy
    Am J Hypertens 20:417-22. 2007
    ..Aim of this study was to evaluate the effect of the telmisartan-amlodipine combination at different doses on urinary albumin excretion rate (UAER) in hypertensive diabetic patients with microalbuminuria...