Nicola Decaro


Affiliation: University of Bari
Country: Italy


  1. Decaro N, Martella V, Elia G, Desario C, Campolo M, Lorusso E, et al. Tissue distribution of the antigenic variants of canine parvovirus type 2 in dogs. Vet Microbiol. 2007;121:39-44 pubmed
    ..Surprisingly, the nervous tissue was found to contain considerable amounts of CPV nucleic acid. Similar patterns of tissue distribution were observed in all the examined dogs irrespective of the antigenic variant causing the disease...
  2. Decaro N, Desario C, Lucente M, Amorisco F, Campolo M, Elia G, et al. Specific identification of feline panleukopenia virus and its rapid differentiation from canine parvoviruses using minor groove binder probes. J Virol Methods. 2008;147:67-71 pubmed
    ..Using this assay for extensive molecular surveys will provide precise information on the real circulation of the CPV antigenic variants, including the new variant 2c, in cat population worldwide...
  3. Decaro N, Carelli G, Lorusso E, Lucente M, Greco G, Lorusso A, et al. Duplex real-time polymerase chain reaction for simultaneous detection and quantification of Anaplasma marginale and Anaplasma centrale. J Vet Diagn Invest. 2008;20:606-11 pubmed
    ..even if present simultaneously in the same blood samples. Such an assay could be used in pathogenesis studies on bovine acute anaplasmosis...
  4. Decaro N, Campolo M, Lorusso A, Desario C, Mari V, Colaianni M, et al. Experimental infection of dogs with a novel strain of canine coronavirus causing systemic disease and lymphopenia. Vet Microbiol. 2008;128:253-60 pubmed
    ..The present study confirms that strain CB/05 is highly pathogenic for dogs, being able to induce a severe disease (and in some cases the death) even in experimental conditions. ..
  5. Decaro N, Elia G, Martella V, Campolo M, Mari V, Desario C, et al. Immunity after natural exposure to enteric canine coronavirus does not provide complete protection against infection with the new pantropic CB/05 strain. Vaccine. 2010;28:724-9 pubmed publisher
  6. Decaro N, Desario C, Elia G, Mari V, Lucente M, Cordioli P, et al. Serological and molecular evidence that canine respiratory coronavirus is circulating in Italy. Vet Microbiol. 2007;121:225-30 pubmed
    ..The results of the present study show that CRCoV is present also in continental Europe, although further studies are required to determine the real pathogenic potential of the virus. ..
  7. Decaro N, Mari V, Campolo M, Lorusso A, Camero M, Elia G, et al. Recombinant canine coronaviruses related to transmissible gastroenteritis virus of Swine are circulating in dogs. J Virol. 2009;83:1532-7 pubmed publisher
    ..By virus neutralization tests, antigenic differences between reference and TGEV-like CCoVs were found. Our data support the potential recombinant origin of the TGEV-like CCoVs. ..
  8. Decaro N, Martella V, Desario C, Bellacicco A, Camero M, Manna L, et al. First detection of canine parvovirus type 2c in pups with haemorrhagic enteritis in Spain. J Vet Med B Infect Dis Vet Public Health. 2006;53:468-72 pubmed
    ..We suggest that this new antigenic variant of CPV-2 could spread throughout Europe and that there is a subsequent need to update current CPV vaccines. ..
  9. Decaro N, Elia G, Campolo M, Desario C, Lucente M, Bellacicco A, et al. New approaches for the molecular characterization of canine parvovirus type 2 strains. J Vet Med B Infect Dis Vet Public Health. 2005;52:316-9 pubmed
    ..Therefore, the MGB probe assays represent a quick, reliable tool for prediction of CPV-2 antigen specificity, with regard to the more time-consuming assays currently used. ..

More Information


  1. Decaro N, Buonavoglia D, Desario C, Amorisco F, Colaianni M, Parisi A, et al. Characterisation of canine parvovirus strains isolated from cats with feline panleukopenia. Res Vet Sci. 2010;89:275-8 pubmed publisher
    ..Whether and to which extent the FPL vaccines can protect cats adequately from the antigenic variants of CPV-2 should be assessed. ..
  2. Decaro N, Desario C, Billi M, Mari V, Elia G, Cavalli A, et al. Western European epidemiological survey for parvovirus and coronavirus infections in dogs. Vet J. 2011;187:195-9 pubmed publisher
    ..Except for the UK, CCoV genotype I was identified in all European countries involved in the survey, albeit at a lower prevalence rates than CCoV genotype II. ..
  3. Decaro N, Martella V, Elia G, Desario C, Campolo M, Buonavoglia D, et al. Diagnostic tools based on minor groove binder probe technology for rapid identification of vaccinal and field strains of canine parvovirus type 2b. J Virol Methods. 2006;138:10-6 pubmed
    ..These new assays will help resolution of the diagnostic problems related to the detection of a type 2b strain in the faeces of dogs shortly after the administration of a type 2b vaccine. ..
  4. Decaro N, Desario C, Addie D, Martella V, Vieira M, Elia G, et al. The study molecular epidemiology of canine parvovirus, Europe. Emerg Infect Dis. 2007;13:1222-4 pubmed
    ..Molecular method assessment of the distribution of the CPV variants in Europe showed that the new variant CPV-2c is widespread in Europe and that the viruses are distributed in different countries. ..
  5. Decaro N, Mari V, Elia G, Addie D, Camero M, Lucente M, et al. Recombinant canine coronaviruses in dogs, Europe. Emerg Infect Dis. 2010;16:41-7 pubmed publisher
    ..87% and 3.45%, respectively). Sequence and phylogenetic analyses showed that the CCoV-IIb strains were related to prototype TGEV-like strains in the 5' and the 3' ends of the spike protein gene. ..
  6. Decaro N, Desario C, Elia G, Campolo M, Lorusso A, Mari V, et al. Occurrence of severe gastroenteritis in pups after canine parvovirus vaccine administration: a clinical and laboratory diagnostic dilemma. Vaccine. 2007;25:1161-6 pubmed
  7. Decaro N, Desario C, Amorisco F, Losurdo M, Colaianni M, Greco M, et al. Canine parvovirus type 2c infection in a kitten associated with intracranial abscess and convulsions. J Feline Med Surg. 2011;13:231-6 pubmed publisher
    ..Continuous surveillance is needed to monitor future spreading of this CPV-2c mutant, and any associated clinical signs, in the dog and cat population. ..
  8. Decaro N, Desario C, Parisi A, Martella V, Lorusso A, Miccolupo A, et al. Genetic analysis of canine parvovirus type 2c. Virology. 2009;385:5-10 pubmed publisher
    ..Analysis of the selection pressure driving CPV evolution confirmed that the VP2 gene is under purifying selection. The emergence and global spread of the new CPV variant provides an interesting model to better understand virus evolution...
  9. Decaro N, Mari V, Lucente M, Sciarretta R, Moreno A, Armenise C, et al. Experimental infection of cattle, sheep and pigs with 'Hobi'-like pestivirus. Vet Microbiol. 2012;155:165-71 pubmed publisher
    ..Nevertheless, the presence of detectable antibodies by virus neutralisation accounted for a successful, albeit limited infection of these animals...
  10. Decaro N, Campolo M, Desario C, Ricci D, Camero M, Lorusso E, et al. Virological and molecular characterization of a mammalian orthoreovirus type 3 strain isolated from a dog in Italy. Vet Microbiol. 2005;109:19-27 pubmed
    ..77%) observed in dogs...
  11. Decaro N, Buonavoglia C. Canine parvovirus--a review of epidemiological and diagnostic aspects, with emphasis on type 2c. Vet Microbiol. 2012;155:1-12 pubmed publisher
    ..Continuous surveillance will help assess whether there is a real need to update currently available vaccines and diagnostic tests...
  12. Decaro N, Sciarretta R, Lucente M, Mari V, Amorisco F, Colaianni M, et al. A nested PCR approach for unambiguous typing of pestiviruses infecting cattle. Mol Cell Probes. 2012;26:42-6 pubmed publisher
  13. Decaro N, Lucente M, Mari V, Sciarretta R, Pinto P, Buonavoglia D, et al. Hobi-like pestivirus in aborted bovine fetuses. J Clin Microbiol. 2012;50:509-12 pubmed publisher
    ..These findings may have important implications for the pestivirus control/eradication programs in cattle herds...
  14. Decaro N, Desario C, Miccolupo A, Campolo M, Parisi A, Martella V, et al. Genetic analysis of feline panleukopenia viruses from cats with gastroenteritis. J Gen Virol. 2008;89:2290-8 pubmed publisher
  15. Decaro N, Campolo M, Elia G, Buonavoglia D, Colaianni M, LoRusso A, et al. Infectious canine hepatitis: an "old" disease reemerging in Italy. Res Vet Sci. 2007;83:269-73 pubmed
    ..The present study shows that CAV-1 is currently circulating in the Italian dog population and that vaccination is still required...
  16. Decaro N, Elia G, Martella V, Campolo M, Desario C, Camero M, et al. Characterisation of the canine parvovirus type 2 variants using minor groove binder probe technology. J Virol Methods. 2006;133:92-9 pubmed
    ..These results make the established MGB probe assays an attractive tool for direct and rapid characterisation of type 2a, 2b and 2c CPVs...
  17. Campolo M, Desario C, Ricci D, Elia G, Decaro N, Martella V, et al. Identification of a feline coronavirus type I strain from a cat with feline infectious peritonitis by RT-pCR and phylogenetic analysis. New Microbiol. 2005;28:127-33 pubmed
    ..The RT-PCR results were confirmed by sequence analysis of the amplified products. Phylogeny carried out on fragments of the M and S genes showed that the FCoV strain segregates with typical type I FCoVs...
  18. Decaro N, Desario C, Elia G, Martella V, Mari V, Lavazza A, et al. Evidence for immunisation failure in vaccinated adult dogs infected with canine parvovirus type 2c. New Microbiol. 2008;31:125-30 pubmed
  19. Decaro N, Amorisco F, Desario C, Lorusso E, Camero M, Bellacicco A, et al. Development and validation of a real-time PCR assay for specific and sensitive detection of canid herpesvirus 1. J Virol Methods. 2010;169:176-80 pubmed publisher
  20. Decaro N, Elia G, Martella V, Desario C, Campolo M, Trani L, et al. A real-time PCR assay for rapid detection and quantitation of canine parvovirus type 2 in the feces of dogs. Vet Microbiol. 2005;105:19-28 pubmed
    ..Comparison between these different techniques revealed that real-time PCR is more sensitive than HA and conventional gel-based PCR, allowing to detect low viral titers of CPV-2 in infected dogs...
  21. Mitchell J, Cardwell J, Leach H, Walker C, Le Poder S, Decaro N, et al. European surveillance of emerging pathogens associated with canine infectious respiratory disease. Vet Microbiol. 2017;212:31-38 pubmed publisher
    ..cynos and influenza A in CIRD was less apparent. Despite 45% of dogs being seropositive for M. cynos, only 0.9% were PCR positive for M. cynos. Only 2.7% of dogs were seropositive for Influenza A, and none were positive by PCR. ..