Roberto de Franchis

Summary

Affiliation: University of Milan
Country: Italy

Publications

  1. ncbi request reprint Evolving consensus in portal hypertension. Report of the Baveno IV consensus workshop on methodology of diagnosis and therapy in portal hypertension
    Roberto de Franchis
    Gastroenterology and Gastrointestinal Endoscopy Service, Department of Internal Medicine, University of Milan, IRCCS Ospedale Maggiore Policlinico, Via Pace 9, 20122 Milan, Italy
    J Hepatol 43:167-76. 2005
  2. ncbi request reprint Diagnosis and therapy of esophageal vascular disorders
    Roberto de Franchis
    Department of Medical Sciences, University of Milan, and Gastroenterology and Gastrointestinal Endoscopy Unit, Ospedale Policlinico, Mangiagalli and Regina Elena Foundation, Milan, Italy
    Curr Opin Gastroenterol 23:422-7. 2007
  3. doi request reprint Diagnosis and monitoring of portal hypertension
    R de Franchis
    Department of Medical Sciences, University of Milan, Italy
    Dig Liver Dis 40:312-7. 2008
  4. doi request reprint Esophageal capsule endoscopy for screening and surveillance of esophageal varices in patients with portal hypertension
    Roberto de Franchis
    Department of Medical Sciences, University of Milan, Istituto di Ricovero e Cura a Carattere Scientifico Fondazione Ospedale Maggiore Policlinico, Mangiagalli and Regina Elena, Milan, Italy
    Hepatology 47:1595-603. 2008
  5. ncbi request reprint Non-invasive diagnosis of cirrhosis and the natural history of its complications
    Roberto de Franchis
    IRCCS Ospedale Maggiore Policlinico, Mangiagalli and Regina Elena Foundation, Department of Medical Sciences, University of Milan, Via Pace 9, 20122 Milan, Italy
    Best Pract Res Clin Gastroenterol 21:3-18. 2007
  6. doi request reprint Novel developments in esophageal vascular disorders
    Roberto de Franchis
    Department of Medical Sciences, University of Milan, Milan, Italy
    Curr Opin Gastroenterol 24:490-5. 2008
  7. doi request reprint Non-invasive (and minimally invasive) diagnosis of oesophageal varices
    Roberto de Franchis
    Department of Medical Sciences, University of Milan, Fondazione Ospedale IRCCS Maggiore Policlinico, Mangiagalli and Regina Elena, Milan, Italy
    J Hepatol 49:520-7. 2008
  8. ncbi request reprint ICCE consensus for bowel preparation and prokinetics
    R de Franchis
    Dept of Internal Medicine, University of Milan, Milan, Italy
    Endoscopy 37:1040-5. 2005
  9. ncbi request reprint Capsule endoscopy--state of the art
    Roberto de Franchis
    Department of Medical Sciences, University of Milan, Milan, Italy
    Dig Dis 25:249-51. 2007
  10. ncbi request reprint Portal hypertensive enteropathy
    Emanuele Rondonotti
    Gastroenterology and Gastrointestinal Endoscopy Unit, Ospedale Maggiore Policlinico, University of Milan, Via Pace 9, Milan 20122, Italy
    Gastrointest Endosc Clin N Am 16:277-86. 2006

Collaborators

Detail Information

Publications50

  1. ncbi request reprint Evolving consensus in portal hypertension. Report of the Baveno IV consensus workshop on methodology of diagnosis and therapy in portal hypertension
    Roberto de Franchis
    Gastroenterology and Gastrointestinal Endoscopy Service, Department of Internal Medicine, University of Milan, IRCCS Ospedale Maggiore Policlinico, Via Pace 9, 20122 Milan, Italy
    J Hepatol 43:167-76. 2005
  2. ncbi request reprint Diagnosis and therapy of esophageal vascular disorders
    Roberto de Franchis
    Department of Medical Sciences, University of Milan, and Gastroenterology and Gastrointestinal Endoscopy Unit, Ospedale Policlinico, Mangiagalli and Regina Elena Foundation, Milan, Italy
    Curr Opin Gastroenterol 23:422-7. 2007
    ..The most relevant studies concerning the diagnosis of esophageal varices, primary and secondary prophylaxis and treatment of variceal bleeding published in the last year are reported...
  3. doi request reprint Diagnosis and monitoring of portal hypertension
    R de Franchis
    Department of Medical Sciences, University of Milan, Italy
    Dig Liver Dis 40:312-7. 2008
    ....
  4. doi request reprint Esophageal capsule endoscopy for screening and surveillance of esophageal varices in patients with portal hypertension
    Roberto de Franchis
    Department of Medical Sciences, University of Milan, Istituto di Ricovero e Cura a Carattere Scientifico Fondazione Ospedale Maggiore Policlinico, Mangiagalli and Regina Elena, Milan, Italy
    Hepatology 47:1595-603. 2008
    ..However, the minimal invasiveness, good tolerance, and good agreement of capsule endoscopy with EGD might increase adherence to screening programs. Whether this is the case needs to be determined...
  5. ncbi request reprint Non-invasive diagnosis of cirrhosis and the natural history of its complications
    Roberto de Franchis
    IRCCS Ospedale Maggiore Policlinico, Mangiagalli and Regina Elena Foundation, Department of Medical Sciences, University of Milan, Via Pace 9, 20122 Milan, Italy
    Best Pract Res Clin Gastroenterol 21:3-18. 2007
    ..Bleeding stops spontaneously in about 50% of cases but early rebleeding occurs in 30-40% of patients. Bleeding-related mortality has declined over time and is now around 20% at 6 weeks...
  6. doi request reprint Novel developments in esophageal vascular disorders
    Roberto de Franchis
    Department of Medical Sciences, University of Milan, Milan, Italy
    Curr Opin Gastroenterol 24:490-5. 2008
    ..The aim of this review is to discuss the most important studies published in 2007 concerning diagnosis of esophageal varices, primary and secondary prophylaxis and treatment of variceal bleeding...
  7. doi request reprint Non-invasive (and minimally invasive) diagnosis of oesophageal varices
    Roberto de Franchis
    Department of Medical Sciences, University of Milan, Fondazione Ospedale IRCCS Maggiore Policlinico, Mangiagalli and Regina Elena, Milan, Italy
    J Hepatol 49:520-7. 2008
    ..Whether this will compensate for the lower sensitivity of these alternative techniques, and ultimately improve the outcomes if more patients undergo screening, is the crucial question that will have to be answered in the future...
  8. ncbi request reprint ICCE consensus for bowel preparation and prokinetics
    R de Franchis
    Dept of Internal Medicine, University of Milan, Milan, Italy
    Endoscopy 37:1040-5. 2005
  9. ncbi request reprint Capsule endoscopy--state of the art
    Roberto de Franchis
    Department of Medical Sciences, University of Milan, Milan, Italy
    Dig Dis 25:249-51. 2007
    ..The potential of this capsule for clinical purposes, such as colon cancer screening, needs to be evaluated...
  10. ncbi request reprint Portal hypertensive enteropathy
    Emanuele Rondonotti
    Gastroenterology and Gastrointestinal Endoscopy Unit, Ospedale Maggiore Policlinico, University of Milan, Via Pace 9, Milan 20122, Italy
    Gastrointest Endosc Clin N Am 16:277-86. 2006
    ..Such studies should compare patients who have cirrhosis with healthy subjects. A comparison between cirrhotic patients with a history of intestinal bleeding and bleeding patients without cirrhosis also would be interesting...
  11. doi request reprint The course of esophageal varices in patients with hepatitis C cirrhosis responding to interferon/ribavirin therapy
    Roberta D'Ambrosio
    AM Migliavacca Center for Liver Disease, First Division of Gastroenterology, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Universita degli Studi di Milano, Milan, Italy
    Antivir Ther 16:677-84. 2011
    ..Our aim was to prospectively assess whether a successful IFN therapy modifies development and/or progression of EV in patients with HCV-related compensated cirrhosis...
  12. ncbi request reprint Preparations and prokinetics
    Federica Villa
    Gastroenterology and Gastrointestinal Endoscopy Unit, Ospedale Maggiore Policlinico, Mangiagalli and Regina Elena Foundation, Via Pace 9, Milan 20122, Italy
    Gastrointest Endosc Clin N Am 16:211-20. 2006
    ....
  13. ncbi request reprint Angiotensin-converting enzyme insertion/deletion gene polymorphism in inflammatory bowel diseases
    Simone Saibeni
    Gastroenterology and Gastrointestinal Endoscopy Service, IRCCS Fondazione Ospedale Maggiore Policlinico, Mangiagalli, Regina Elena and University of Milan, Milan, Italy
    Eur J Gastroenterol Hepatol 19:976-81. 2007
    ..The ACE I/D (insertion/deletion) is a polymorphism of the gene encoding for ACE: participants who are homozygous for the D allele exhibit higher ACE levels, which in turn appear to play a deleterious role in several diseases...
  14. doi request reprint Impact of gluten withdrawal on health-related quality of life in celiac subjects: an observational case-control study
    Gian Eugenio Tontini
    University of Milan, Milan, Italy
    Digestion 82:221-8. 2010
    ..To evaluate health-related quality of life (HRQoL) in celiac disease (CD) patients at the time of diagnosis and during a gluten-free diet (GFD)...
  15. doi request reprint Increased thrombin generation in inflammatory bowel diseases
    Simone Saibeni
    Department of Internal Medicine and Hepatology, Azienda Ospedaliera Fatebenefratelli e Oftalmico, Milan, Italy
    Thromb Res 125:278-82. 2010
    ..Endogenous thrombin potential (ETP), a parameter of the thrombin generation curve, represents a new tool in the evaluation of thrombotic and bleeding disorders...
  16. ncbi request reprint Imaging of the small bowel in Crohn's disease: a review of old and new techniques
    Simone Saibeni
    Gastroenterology and Gastrointestinal Endoscopy Unit IRCCS Policlinico San Donato, Via Morandi 30, 20097 San Donato Milanese, Milan, Italy
    World J Gastroenterol 13:3279-87. 2007
    ..The recent development of innovative imaging techniques has opened a new and exciting area in the exploration of the small bowel in Crohn's disease patients...
  17. doi request reprint Sustained virologic response prevents the development of esophageal varices in compensated, Child-Pugh class A hepatitis C virus-induced cirrhosis. A 12-year prospective follow-up study
    Savino Bruno
    Department of Internal Medicine, A O Fatebenefratelli e Oftalmico, Milan, Italy
    Hepatology 51:2069-76. 2010
    ..40; 95% confidence interval [CI] 1.17-4.90) and baseline model for end-stage liver disease (MELD) score (HR 1.20; 95% CI 1.07-1.35 for 1 point increase) were independent predictors of EV...
  18. ncbi request reprint Small bowel capsule endoscopy in 2007: indications, risks and limitations
    Emanuele Rondonotti
    Universuta degli Studi di Milano, IRCCS Fondazione Policlinico, Mangiagalli, Regina Elena, Unita Operativa di Gastroenterologia 3, Via Pace 9, Milano 20122, Italy
    World J Gastroenterol 13:6140-9. 2007
    ....
  19. doi request reprint Enteroscopy in the diagnosis and management of celiac disease
    Emanuele Rondonotti
    Department of Medical Sciences, Gastroenterology 3 Unit, University of Milan, IRCCS Policlinico, Mangiagalli, Regina Elena Foundation, 20122 Milan, Italy
    Gastrointest Endosc Clin N Am 19:445-60. 2009
    ....
  20. ncbi request reprint Onset of inflammatory bowel diseases during combined alpha-interferon and ribavirin therapy for chronic hepatitis C: report of two cases
    Federica Villa
    Department of Gastroenterology, IRCCS Policlinico Hospital, Mangiagalli and Regina Elena Foundation, University of Milan, Italy
    Eur J Gastroenterol Hepatol 17:1243-5. 2005
    ..The history, therapeutic management and the possible causal relationships of these cases are discussed...
  21. doi request reprint Portal vein thrombosis in inflammatory bowel diseases: a single-center case series
    Giovanni Maconi
    Gastrointestinal Unit, Department of Clinical Sciences, L Sacco University Hospital, Milan, Italy
    J Crohns Colitis 6:362-7. 2012
    ..Four patients received anticoagulant therapy for 6 months. None experienced other thrombotic events during a median of 5 years (range 2-8 years)...
  22. ncbi request reprint Complications, limitations, and failures of capsule endoscopy: a review of 733 cases
    Emanuele Rondonotti
    Gastroenterology and GI Endoscopy Service, IRCCS Maggiore Policlinico Hospital, University of Milan, Milan, Italy
    Gastrointest Endosc 62:712-6; quiz 752, 754. 2005
    ..Although a variety of technical and clinical problems of capsule endoscopy have been reported, their incidence and clinical importance are unknown. The objective was to evaluate the incidence and the type of such events...
  23. ncbi request reprint Small bowel malignancy
    Roberto de Franchis
    Department of Internal Medicine, University of Milan, IRCCS Ospedale Policlinico, Via Pace 9, 20122 Milan, Italy
    Gastrointest Endosc Clin N Am 14:139-48. 2004
  24. ncbi request reprint Thrombosis in inflammatory bowel diseases: role of inherited thrombophilia
    Luisa Spina
    Gastroenterology and Gastrointestinal Endoscopy Service, Hepatology Unit, IRCCS Maggiore Hospital, Mangiagalli, Italy
    Am J Gastroenterol 100:2036-41. 2005
    ..Although the pathogenetic mechanisms of this predisposition are unclear, a possible role of inherited risk factors for thrombosis in determining this predisposition has been suggested...
  25. doi request reprint An imbalance of pro- vs anti-coagulation factors in plasma from patients with cirrhosis
    Armando Tripodi
    Department of Internal Medicine and Medical Specialties, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milano, Italy
    Gastroenterology 137:2105-11. 2009
    ..We investigated whether plasma from cirrhotic patients has an imbalance of pro- vs anti-coagulation factors...
  26. doi request reprint Cost estimation of small bowel capsule endoscopy based on "real world" data: inpatient or outpatient procedure?
    Emanuele Rondonotti
    Congregazione Suore Infermiere dell Addolorata, Ospedale Valduce, U O C, Gastroenterologia, Como CO, Italy
    Dig Liver Dis 42:798-802. 2010
    ..Although capsule endoscopy is the cornerstone for the evaluation of the small bowel in patients with obscure GI bleeding data about costs are lacking...
  27. doi request reprint Small bowel capsule endoscopy in clinical practice: a multicenter 7-year survey
    Emanuele Rondonotti
    Universita degli Studi di Milano, IRCCS Fondazione Policlinico, Mangiagalli, Regina Elena, Dipartimento di Scienze Mediche, Gastroenterologia 3, Milano, Italy
    Eur J Gastroenterol Hepatol 22:1380-6. 2010
    ..The study aim was to describe extent of use, indications, results, complications, and practical issues of SBCE in clinical practice in a Northern Italian Region (Lombardia)...
  28. ncbi request reprint Prevalence of hyperhomocysteinemia in adult gluten-sensitive enteropathy at diagnosis: role of B12, folate, and genetics
    Simone Saibeni
    Gastroenterology and Gastrointestinal Endoscopy Service, IRCCS Maggiore Hospital and University of Milan, Milan, Italy
    Clin Gastroenterol Hepatol 3:574-80. 2005
    ..We evaluated the prevalence and the risk factors for hyperhomocysteinemia in patients with newly diagnosed GSE...
  29. ncbi request reprint Incidental esophageal varices
    Roberto de Franchis
    Gastroenterology and Gastrointestinal Endoscopy Service, University of Milan, IRCCS Policlinico Hospital, Via Pace 9, 20122 Milan, Italy
    Gastroenterology 126:1860-7. 2004
  30. doi request reprint A 28-year study of the course of hepatitis Delta infection: a risk factor for cirrhosis and hepatocellular carcinoma
    Raffaella Romeo
    A M Migliavacca Center, First Division of Gastroenterology, IRCCS Maggiore Hospital, University of Milan, Milan, Italy
    Gastroenterology 136:1629-38. 2009
    ..We tracked the course of HDV infection in 299 patients over a mean period of 233 months...
  31. ncbi request reprint Video capsule enteroscopy in the diagnosis of celiac disease: a multicenter study
    Emanuele Rondonotti
    Department of Medical Sciences, University of Milan and Gastroenterology and GI Endoscopy Unit, Ospedale Maggiore Policlinico, Mangiagalli and Regina Elena Foundation, Milan, Italy
    Am J Gastroenterol 102:1624-31. 2007
    ..We evaluated the potential of videocapsule endoscopy in assessing the severity and extent of mucosal changes in patients with suspected celiac disease...
  32. ncbi request reprint Pathogenesis of ascites and predictors of resistance to therapy
    Roberto de Franchis
    Gastroenterology and Gastrointestinal Endoscopy Service, IRCCS Ospedale Policlinico, Department of Internal Medicine, University of Milan, Milan, Italy
    J Gastroenterol Hepatol 17:S242-7. 2002
    ..However, as the mechanisms of refractoriness are associated with advanced disease and short survival, the models developed for predicting survival should be employed also to verify if they can exert such additional prediction...
  33. ncbi request reprint Gender and disease activity influence health-related quality of life in inflammatory bowel diseases
    Simone Saibeni
    Gastroenterology Service, University of Milan, IRCCS Ospedale Policlinico, Milan, Italy
    Hepatogastroenterology 52:509-15. 2005
    ....
  34. doi request reprint Successful resolution of bowel obstruction in a patient with hereditary angioedema
    Lorenza C Zingale
    Department of Clinical Science L Sacco, University of Milan, Ospedale L Sacco, Milan, Italy
    Eur J Gastroenterol Hepatol 20:583-7. 2008
    ..Furthermore, it illustrates the usefulness of videos obtained from capsule endoscopy in identifying the presence of bowel occlusion and demonstrating its subsequent rapid resolution upon administration of DX-88...
  35. ncbi request reprint Kallikrein-kinin system activation in Crohn's disease: differences in intestinal and systemic markers
    Massimo Devani
    Department of Internal Medicine, Instituto di Ricovero e Cura a Carattere Scientifico Ospedale Maggiore and University of Milan, Italy
    Am J Gastroenterol 97:2026-32. 2002
    ..The aim of this study was to assess activation of the plasma and tissue kallikrein-kinin system in Crohn's disease...
  36. ncbi request reprint Gastroduodenal lesions in polycythaemia vera: frequency and role of Helicobacter pylori
    Giuseppe Torgano
    Emergency Department, University of Milan, IRCCS Ospedale Maggiore, Italy
    Br J Haematol 117:198-202. 2002
    ..The higher susceptibility of H. pylori infection and the high frequency of asymptomatic gastroduodenal lesions in PV patients suggest a surveillance of these patients...
  37. ncbi request reprint Low vitamin B(6) plasma levels, a risk factor for thrombosis, in inflammatory bowel disease: role of inflammation and correlation with acute phase reactants
    Simone Saibeni
    Gastroenterology and Gastrointestinal Endoscopy Service, Bianchi Bonomi Haemophilia and Thrombosis Center, IRCCS Maggiore Hospital and University of Milan, Milan, Italy
    Am J Gastroenterol 98:112-7. 2003
    ..The aim of this study was to evaluate vitamin B(6) plasma levels in IBD patients...
  38. ncbi request reprint Nadolol is superior to isosorbide mononitrate for the prevention of the first variceal bleeding in cirrhotic patients with ascites
    Gianmario Borroni
    Medicina Generale, Ospedale G Fornaroli, Magenta, Italy
    J Hepatol 37:315-21. 2002
    ....
  39. ncbi request reprint Expert pediatric opinion on the Report of the Baveno IV consensus workshop on methodology of diagnosis and therapy in portal hypertension
    Benjamin Shneider
    Division of Pediatric Hepatology, Department of Pediatrics, Mount Sinai School of Medicine, New York, NY 10029, USA
    Pediatr Transplant 10:893-907. 2006
    ....
  40. ncbi request reprint Video capsule endoscopy and histology for small-bowel mucosa evaluation: a comparison performed by blinded observers
    Federico Biagi
    First Department of Internal Medicine, IRCCS Policlinico San Matteo, University of Pavia, Italy
    Clin Gastroenterol Hepatol 4:998-1003. 2006
    ..We studied whether the capsule can discriminate different degrees of mucosal damage caused by different conditions; we also evaluated interobserver and intraobserver variability in the assessment of villous atrophy with the capsule...
  41. ncbi request reprint Endoscopy critics vs. endoscopy enthusiasts for primary prophylaxis of variceal bleeding
    Roberto de Franchis
    Hepatology 43:24-6. 2006
  42. doi request reprint Recombinant factor VIIa for variceal bleeding in patients with advanced cirrhosis: A randomized, controlled trial
    Jaime Bosch
    Hepatic Hemodynamic Laboratory, Hospital Clinic and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBEREHD, University of Barcelona, Spain
    Hepatology 47:1604-14. 2008
    ..A marked heterogeneity in the failure rate in all treatment groups was observed across participating centers. Adverse events, including overall thromboembolic events, were comparable between groups...
  43. ncbi request reprint Noninvasive diagnosis of esophageal varices: is it feasible?
    Roberto de Franchis
    Am J Gastroenterol 101:2520-2. 2006
    ..However, the available evidence is not yet sufficient to allow for the modification of the current policy of screening cirrhotic patients by endoscopy at the time of diagnosis to detect varices...
  44. ncbi request reprint Capsule enteroscopy vs. other diagnostic procedures in diagnosing obscure gastrointestinal bleeding: a cost-effectiveness study
    Riccardo Marmo
    Division of Gastroenterology, L Curto Hospital, Polla, Sant Arsenio, Italy
    Eur J Gastroenterol Hepatol 19:535-42. 2007
    ..The costs of capsule enteroscopy examination, however, make it uncertain whether the clinically relevant diagnostic gain is also associated with cost savings...
  45. ncbi request reprint Recombinant factor VIIa for upper gastrointestinal bleeding in patients with cirrhosis: a randomized, double-blind trial
    Jaime Bosch
    Hospital Clinic, Liver Unit, Barcelona, Spain
    Gastroenterology 127:1123-30. 2004
    ..This trial aimed to determine efficacy and safety of rFVIIa in cirrhotic patients with variceal and nonvariceal UGIB...
  46. ncbi request reprint Evaluation and follow-up of patients with cirrhosis and oesophageal varices
    Roberto de Franchis
    J Hepatol 38:361-3. 2003
  47. ncbi request reprint Upper digestive bleeding in cirrhosis. Post-therapeutic outcome and prognostic indicators
    Gennaro D'Amico
    Department of Medicine, Ospedale V Cervello, Palermo, Italy
    Hepatology 38:599-612. 2003
    ..Initial treatment stops bleeding in 90% of patients. Accurate predictive rules are provided for early recognition of high-risk patients...
  48. ncbi request reprint Increased survival of cirrhotic patients with a hepatocellular carcinoma detected during surveillance
    Angelo Sangiovanni
    Department of Gastroenterology and Endocirnology, A M and A Migliavacca Center for Liver Diseases, FIRC Unit on Liver Cancer, IRCSS Maggiore Hospital and University of Milan, Italy
    Gastroenterology 126:1005-14. 2004
    ..To clarify this, we compared survival of HCC patients identified along 3 consecutive quinquennia of surveillance...
  49. ncbi request reprint EASL International Consensus Conference on Hepatitis B. 13-14 September, 2002 Geneva, Switzerland. Consensus statement (long version)
    Roberto de Franchis
    J Hepatol 39:S3-25. 2003
  50. ncbi request reprint Outcome of patients with obscure gastrointestinal bleeding after capsule endoscopy: report of 100 consecutive cases
    Marco Pennazio
    Division of Gastroenterology, S Giovanni Antica Sede Hospital, Turin, Italy
    Gastroenterology 126:643-53. 2004
    ..However, the diagnostic yield of this technique has not been adequately studied. We evaluated sensitivity and specificity of CE and the outcome after CE in patients with obscure gastrointestinal bleeding...