Massimo De Paoli

Summary

Affiliation: University of Padova
Country: Italy

Publications

  1. ncbi request reprint Clinical value and measurement of specific IgE
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, and Centre for Biomedical Research, Castelfranco, Veneto, Italy
    Clin Biochem 36:453-69. 2003
  2. doi request reprint The detection and prevention of errors in laboratory medicine
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy
    Ann Clin Biochem 47:101-10. 2010
  3. ncbi request reprint Promoting clinical and laboratory interaction by harmonization
    Mario Plebani
    Department of Laboratory Medicine, University Hospital, Padova, Italy Electronic address
    Clin Chim Acta 432:15-21. 2014
  4. ncbi request reprint Quality indicators to detect pre-analytical errors in laboratory testing
    M Plebani
    Department of Laboratory Medicine, University Hospital, Padova, Italy Electronic address
    Clin Chim Acta 432:44-8. 2014
  5. doi request reprint Harmonization of pre-analytical quality indicators
    Mario Plebani
    Department of Laboratory Medicine, University Hospital, Padova, Italy
    Biochem Med (Zagreb) 24:105-13. 2014
  6. doi request reprint Utilization management: a European perspective
    Mario Plebani
    Department of Laboratory Medicine, University Hospital, Padova, Italy Electronic address
    Clin Chim Acta 427:137-41. 2014
  7. doi request reprint Quality indicators in laboratory medicine: a fundamental tool for quality and patient safety
    Mario Plebani
    Department of Laboratory Medicine, University Hospital, Padova, Italy
    Clin Biochem 46:1170-4. 2013
  8. doi request reprint Harmonization in laboratory medicine: the complete picture
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padua, 35128 Padua, Italy
    Clin Chem Lab Med 51:741-51. 2013
  9. ncbi request reprint HE4 in gynecological cancers: report of a European investigators and experts meeting
    Mario Plebani
    Department of Laboratory Medicine, Padua University Hospital, Padua, Italy
    Clin Chem Lab Med 50:2127-36. 2012
  10. doi request reprint Towards harmonization of quality indicators in laboratory medicine
    Mario Plebani
    Department of Laboratory Medicine, Padua University Hospital, Padua, Italy
    Clin Chem Lab Med 51:187-95. 2013

Detail Information

Publications127 found, 100 shown here

  1. ncbi request reprint Clinical value and measurement of specific IgE
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, and Centre for Biomedical Research, Castelfranco, Veneto, Italy
    Clin Biochem 36:453-69. 2003
    ..Characterization of allergens at a molecular and submolecular level and, where necessary, the use of recombinant allergens can reduce cross-reactions and further improve the quality of immunoassays...
  2. doi request reprint The detection and prevention of errors in laboratory medicine
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy
    Ann Clin Biochem 47:101-10. 2010
    ....
  3. ncbi request reprint Promoting clinical and laboratory interaction by harmonization
    Mario Plebani
    Department of Laboratory Medicine, University Hospital, Padova, Italy Electronic address
    Clin Chim Acta 432:15-21. 2014
    ....
  4. ncbi request reprint Quality indicators to detect pre-analytical errors in laboratory testing
    M Plebani
    Department of Laboratory Medicine, University Hospital, Padova, Italy Electronic address
    Clin Chim Acta 432:44-8. 2014
    ..It, moreover, provides the framework (with objective criteria) necessary for promoting the harmonization of available QIs in the pre-analytical phase. ..
  5. doi request reprint Harmonization of pre-analytical quality indicators
    Mario Plebani
    Department of Laboratory Medicine, University Hospital, Padova, Italy
    Biochem Med (Zagreb) 24:105-13. 2014
    ....
  6. doi request reprint Utilization management: a European perspective
    Mario Plebani
    Department of Laboratory Medicine, University Hospital, Padova, Italy Electronic address
    Clin Chim Acta 427:137-41. 2014
    ..Therefore, the use of approaches for demand management that considers pre-, within- and post-laboratory initiatives is on the increase in clinical laboratories throughout Europe. ..
  7. doi request reprint Quality indicators in laboratory medicine: a fundamental tool for quality and patient safety
    Mario Plebani
    Department of Laboratory Medicine, University Hospital, Padova, Italy
    Clin Biochem 46:1170-4. 2013
    ..The current lack of attention to extra-laboratory factors is in stark contrast with the body of evidence pointing to the multitude of errors that continue to occur in the pre- and post-analytical phases...
  8. doi request reprint Harmonization in laboratory medicine: the complete picture
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padua, 35128 Padua, Italy
    Clin Chem Lab Med 51:741-51. 2013
    ....
  9. ncbi request reprint HE4 in gynecological cancers: report of a European investigators and experts meeting
    Mario Plebani
    Department of Laboratory Medicine, Padua University Hospital, Padua, Italy
    Clin Chem Lab Med 50:2127-36. 2012
    ..Available evidences support the utility of this new cancer biomarker for risk stratification,prognosis and monitoring of epithelial ovarian cancer and of endometrial cancer...
  10. doi request reprint Towards harmonization of quality indicators in laboratory medicine
    Mario Plebani
    Department of Laboratory Medicine, Padua University Hospital, Padua, Italy
    Clin Chem Lab Med 51:187-95. 2013
    ..The identification of valuable QIs is a key step in paving the way towards quality and patient safety in laboratory medicine...
  11. doi request reprint The CCLM contribution to improvements in quality and patient safety
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padua, Padua, Italy
    Clin Chem Lab Med 51:39-46. 2013
    ....
  12. doi request reprint Patient safety and quality in laboratory and hemostasis testing: a renewed loop?
    Mario Plebani
    Dipartimento Medicina di Laboratorio, Azienda Ospedaliera Universita di Padova, Padova, Italy
    Semin Thromb Hemost 38:553-8. 2012
    ..This article overviews the concept of quality testing within hemostasis as critical to ensuring patient safety and optimal clinical and therapeutic management...
  13. pmc Tumor marker utility and prognostic relevance of cathepsin B, cathepsin L, urokinase-type plasminogen activator, plasminogen activator inhibitor type-1, CEA and CA 19-9 in colorectal cancer
    Laszlo Herszenyi
    2nd Department of Medicine, Semmelweis University, Budapest Hungarian Academy of Science, Clinical Gastroenterology Research Unit, Budapest, Hungary
    BMC Cancer 8:194. 2008
    ..The tumor marker utility and prognostic relevance of these proteases have not been evaluated in the same experimental setting and compared with that of CEA and CA-19-9...
  14. doi request reprint Exploring the iceberg of errors in laboratory medicine
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, Italy
    Clin Chim Acta 404:16-23. 2009
    ..The lesson we have learned is that each practice must examine its own total testing process to discover its weaknesses and identify appropriate remedies...
  15. doi request reprint Does POCT reduce the risk of error in laboratory testing?
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy
    Clin Chim Acta 404:59-64. 2009
    ..There is therefore an urgent need for an evaluation of errors and risks of error in POCT that is based on the entire testing process and uses well-designed studies aiming to improve clinical outcomes and increase patient safety...
  16. doi request reprint Interpretative commenting: a tool for improving the laboratory-clinical interface
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy
    Clin Chim Acta 404:46-51. 2009
    ..Moreover, quality assurance programs and an appropriate clinical audit are required to evaluate and improve upon this activity...
  17. doi request reprint Quality control in coagulation testing
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, Italy
    Semin Thromb Hemost 34:642-6. 2008
    ..New challenges to EQA schemes for coagulation testing derive from the introduction of innovative tests, genetic analysis, and the need to assess not only analytical procedures but also all steps included in the total testing process...
  18. doi request reprint Recent advances in diagnostic technologies for autoimmune diseases
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, Italy
    Autoimmun Rev 8:238-43. 2009
    ....
  19. doi request reprint The changing scenario in laboratory medicine and the role of laboratory professionals in translational medicine
    Mario Plebani
    Department of Laboratory Medicine, Azienda Ospedaliera Universita di Padova, Via Giustiniani, 2, 35128 Padova, Italy
    Clin Chim Acta 393:23-6. 2008
    ....
  20. ncbi request reprint Errors in clinical laboratories or errors in laboratory medicine?
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova and Center of Biomedical Research, Castelfranco Veneto, Italy
    Clin Chem Lab Med 44:750-9. 2006
    ..In a modern approach to total quality, centered on patients' needs and satisfaction, the risk of errors and mistakes in pre- and post-examination steps must be minimized to guarantee the total quality of laboratory services...
  21. ncbi request reprint Errors in laboratory medicine and patient safety: the road ahead
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova and Center for Biomedical Research, Castelfranco Veneto, Italy
    Clin Chem Lab Med 45:700-7. 2007
    ..Moreover, a fundamental shift in improving patient safety in laboratory medicine is to move from error reporting to risk management...
  22. ncbi request reprint Research translation: a new frontier for clinical laboratories
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, and Center of Biomedical Research, Castelfranco Veneto TV, Italy
    Clin Chem Lab Med 44:1303-12. 2006
    ....
  23. ncbi request reprint Non-invasive assessment of chronic liver and gastric diseases
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, Italy
    Clin Chim Acta 381:39-49. 2007
    ..In these patients, precise definition of the hepatic fibrosis stage is the most important parameter to assess the risk of disease progression and to decide for an immediate and appropriate antiviral therapy...
  24. ncbi request reprint Quality specifications: self pleasure for clinical laboratories or added value for patient management?
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy
    Clin Chem Lab Med 45:462-6. 2007
    ..A consensus should be achieved in the scientific community on these issues to assure better utilization of laboratory data and, ultimately, improved clinical outcomes...
  25. doi request reprint Evaluating laboratory diagnostic tests and translational research
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy
    Clin Chem Lab Med 48:983-8. 2010
    ....
  26. doi request reprint The brain-to-brain loop concept for laboratory testing 40 years after its introduction
    Mario Plebani
    Department of Laboratory Medicine, University of Padova, Italy
    Am J Clin Pathol 136:829-33. 2011
    ..This review describes the changes and their implications for analysis of errors associated with laboratory testing...
  27. doi request reprint Closing the brain-to-brain loop in laboratory testing
    Mario Plebani
    Department of Laboratory Medicine, University Hospital Padova, Padova, Italy
    Clin Chem Lab Med 49:1131-3. 2011
    ....
  28. doi request reprint Antibodies against synthetic deamidated gliadin peptides for celiac disease diagnosis and follow-up in children
    Daniela Basso
    Department of Laboratory Medicine, University of Padova, Italy
    Clin Chem 55:150-7. 2009
    ..AGA IgA II and AGA IgG II have recently been suggested as reliable tools for celiac disease (CD) diagnosis. We compared their utility for diagnosis and monitoring CD in children with that of tTG IgA, an established CD marker...
  29. ncbi request reprint Clarithromycin resistance, tumor necrosis factor alpha gene polymorphism and mucosal inflammation affect H. pylori eradication success
    Carlo Federico Zambon
    Department of Medical and Surgical Sciences, University of Padova, Padova, Italy
    J Gastrointest Surg 11:1506-14; discussion 1514. 2007
    ....
  30. doi request reprint Cytokine network in rectal mucosa in perianal Crohn's disease: relations with inflammatory parameters and need for surgery
    Cesare Ruffolo
    Clinica Chirurgica 1, Department of Surgical and Gastroenterological Sciences, University of Padua, Padova, Italy
    Inflamm Bowel Dis 14:1406-12. 2008
    ..The aim of this study was to assess the cytokine profile in the rectal mucosa of patients affected by perianal CD and to understand its relations with the systemic cytokine profile and inflammatory parameters and the need for surgery...
  31. doi request reprint Clinical relevance of Helicobacter pylori cagA and vacA gene polymorphisms
    Daniela Basso
    Department of Laboratory Medicine, University of Padova, Padova, Italy
    Gastroenterology 135:91-9. 2008
    ..We assessed the association of new and established cagA and vacA polymorphisms with disease...
  32. ncbi request reprint Role of blood AFP mRNA and tumor grade in the preoperative prognostic evaluation of patients with hepatocellular carcinoma
    Umberto Cillo
    Clinica Chirurgica I Dipartimento di Scienze Chirurgiche e Gastroenterologiche Università degli Studi di Padova Via Giustiniani 2, Policlinico III Piano, 35128 Padova, Italy
    World J Gastroenterol 11:6920-5. 2005
    ....
  33. ncbi request reprint Mitochondrial DNA D-loop in pancreatic cancer: somatic mutations are epiphenomena while the germline 16519 T variant worsens metabolism and outcome
    Filippo Navaglia
    Department of Laboratory Medicine, University of Padova, Italy
    Am J Clin Pathol 126:593-601. 2006
    ....
  34. doi request reprint Analogs of vitamin E epitomized by alpha-tocopheryl succinate for pancreatic cancer treatment: in vitro results induce caution for in vivo applications
    Eliana Greco
    Department of Laboratory Medicine, University of Padova, Padova, Italy
    Pancreas 39:662-8. 2010
    ....
  35. doi request reprint Altered intracellular calcium fluxes in pancreatic cancer induced diabetes mellitus: Relevance of the S100A8 N-terminal peptide (NT-S100A8)
    Daniela Basso
    Department of Laboratory Medicine, University of Padua, Padua, Italy
    J Cell Physiol 226:456-68. 2011
    ....
  36. ncbi request reprint Pancreatic cancer-derived S-100A8 N-terminal peptide: a diabetes cause?
    Daniela Basso
    Department of Laboratory Medicine, University of Padua, Via Giustiniani 2, 35128 Padova, Italy
    Clin Chim Acta 372:120-8. 2006
    ..Our aim was to identify the pancreatic cancer diabetogenic peptide...
  37. pmc Molecular refinement of clinical staging in hepatocellular carcinoma patients evaluated for potentially curative therapies
    Alessandro Vitale
    Unità di Chirurgia Epatobiliare e Trapianto Epatico, Dipartimento di Chirurgia Generale e Trapianti d Organo, Universita di Padova, Padova, Italy
    PLoS ONE 6:e23093. 2011
    ..VEGF and AFP mRNA determinations in the blood are promising prognostic factors for patients with HCC. This study explores their potential prognostic synergy in a cohort of HCC patients evaluated for potentially curative therapies...
  38. doi request reprint Pancreatic cancer biomarkers discovery by surface-enhanced laser desorption and ionization time-of-flight mass spectrometry
    Filippo Navaglia
    Department of Laboratory Medicine, University of Padova, Padova, Italy
    Clin Chem Lab Med 47:713-23. 2009
    ..The aim of the present study was to explore the application of SELDI proteomic patterns in serum for distinguishing between cases of pancreatic cancer, chronic pancreatitis, type 2 diabetes mellitus and healthy controls...
  39. doi request reprint TLR2 and TLR4 up-regulation and colonization of the ileal mucosa by Clostridiaceae spp. in chronic/relapsing pouchitis
    Marco Scarpa
    Oncological Surgery Unit, Veneto Institute of Oncology IOV IRCCS, Padova, Italy
    J Surg Res 169:e145-54. 2011
    ..This work examined the interplay between the microbiota adherent to the ileal pouch mucosa and the mucosal immune system in chronic/relapsing pouchitis...
  40. doi request reprint Assessment of critical values policies in Italian institutions: comparison with the US situation
    Elisa Piva
    Department of Laboratory Medicine, University Hospital of Padua, Padua, Italy
    Clin Chem Lab Med 48:461-8. 2010
    ..Here, we report the state of critical value reporting in a large cohort of Italian laboratories and comparison with Q-Probes surveys from the College of American Pathologists as representatives of the US situation...
  41. ncbi request reprint Analytical and clinical evaluation of a new heart-type fatty acid-binding protein automated assay
    Martina Zaninotto
    Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy
    Clin Chem Lab Med 44:1383-5. 2006
    ..Heart-type fatty acid-binding protein (H-FABP) appears to be one of the best candidates among the new early cardiac markers studied...
  42. ncbi request reprint Analytical and clinical performance of a fully automated cardiac multi-markers strategy based on protein biochip microarray technology
    Monica M Mion
    Department of Laboratory Medicine, University Hospital of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Clin Biochem 40:1245-51. 2007
    ..The analytical and clinical performance of the Evidence Cardiac Panel were evaluated...
  43. ncbi request reprint Suicide gene therapy with the yeast fusion gene cytosine deaminase/uracil phosphoribosyltransferase is not enough for pancreatic cancer
    Paola Fogar
    Department of Medical and Surgical Sciences, University of Padova, Padova, Italy
    Pancreas 35:224-31. 2007
    ..We ascertained whether gene therapy with FCY1-FUR1 is effective in killing pancreatic cancer cells after 5-fluorocytosine (5-FC) treatment...
  44. ncbi request reprint High-sensitivity C-reactive protein in umbilical cord of small-for-gestational-age neonates
    Daniele Trevisanuto
    Neonatal Intensive Care Unit, Department of Pediatrics, Medical School, University of Padova Padova Hospital, Azienda Ospedaliera, Padova, Italy
    Neonatology 91:186-9. 2007
    ..We hypothesized that the chronic inflammatory process, involved in the future atherosclerotic injury, could be found during the fetal period...
  45. ncbi request reprint Innotrac Aio!: a point-of-care or a routine analyzer? Analytical performance and plasma/whole blood comparison
    Sara Altinier
    Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy
    Clin Chem Lab Med 44:1278-82. 2006
    ....
  46. ncbi request reprint A new indirect chemiluminescent immunoassay to measure anti-tissue transglutaminase antibodies
    Daniela Basso
    Department of Laboratory Medicine, University of Padova, Padova, Italy
    J Pediatr Gastroenterol Nutr 43:613-8. 2006
    ..p.A., Saluggia, Italy) in diagnosing and monitoring CD in children...
  47. ncbi request reprint DNA repair pathways and mitochondrial DNA mutations in gastrointestinal carcinogenesis
    Daniela Basso
    Department of Laboratory Medicine, University Hospital of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Clin Chim Acta 381:50-5. 2007
    ....
  48. doi request reprint PATHFAST NT-proBNP (N-terminal-pro B type natriuretic peptide): a multicenter evaluation of a new point-of-care assay
    Martina Zaninotto
    Department of Laboratory Medicine, University Hospital, Padova, Italy
    Clin Chem Lab Med 48:1029-34. 2010
    ..These biomarkers have proven to be of particular value in the management of chronic and acute heart failure patients, and in the outpatient and the emergency setting...
  49. ncbi request reprint Acute-phase markers of inflammation and glomerular structure in patients with type 2 diabetes
    Michele Dalla Vestra
    Department of Medical and Surgical Sciences, University of Padova Medical School, Padova, Italy
    J Am Soc Nephrol 16:S78-82. 2005
    ..25 P < 0.05). In conclusion, this study demonstrates that acute-phase markers of inflammation are associated with nephropathy status and GBM thickening, suggesting a role for inflammation in the pathogenesis of diabetic glomerulopathy...
  50. ncbi request reprint Pancreatic cancer-associated diabetes mellitus: an open field for proteomic applications
    Daniela Basso
    Department of Laboratory Medicine, University of Padova, Via Giustiniani 2, Padova 35128, Italy
    Clin Chim Acta 357:184-9. 2005
    ..Clinical, epidemiological, and experimental data indicate that pancreatic cancer causes diabetes mellitus by releasing soluble mediators which interfere with both beta-cell function and liver and muscle glucose metabolism...
  51. ncbi request reprint Syngeneic living-donor liver transplantation for hemangioendothelioma: a clinical model for studying liver regeneration
    Umberto Cillo
    Clinica Chirurgica I, Dipartimento di Chirurgia Generale e Trapianti d Organo, University of Padua, School of Medicine, Padova, Italy
    Am J Transplant 5:2309-14. 2005
    ..Whether this is a potential molecular tool by means of which transplanted partial livers promote their regeneration remains to be seen in a larger number of patients...
  52. doi request reprint Celiac disease in North Italian patients with autoimmune thyroid diseases
    Aglaura Cinzia Spadaccino
    Division of Endocrinology, Department of Medical and Surgical Sciences, University of Padova Medical School, Padova, Italy
    Autoimmunity 41:116-21. 2008
    ..An IgA deficiency is the most frequent immunodeficiency in humans and, in general, high frequency of this disorder was demonstrated in those with autoimmune diseases...
  53. doi request reprint Determinants of circulating asymmetric and symmetric dimethylarginines in patients evaluated for acute dyspnea
    Marta Codognotto
    Department of Medical and Surgical Sciences, University of Padova, Padova, Italy
    Clin Chem Lab Med 49:237-42. 2011
    ..The relationship between asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA) plasma concentrations and acute heart failure is unknown. We evaluated ADMA and SDMA in patients with acute dyspnea...
  54. ncbi request reprint Decreased total lymphocyte counts in pancreatic cancer: an index of adverse outcome
    Paola Fogar
    Department of Medical and Surgical Sciences, University of Padova, Padova, Italy
    Pancreas 32:22-8. 2006
    ..Our aim was to ascertain whether the immunophenotype pattern of blood lymphocytes in PC correlates with tumor stage, grade, or survival...
  55. doi request reprint New screening tests enrich anti-transglutaminase results and support a highly sensitive two-test based strategy for celiac disease diagnosis
    Daniela Basso
    Department of Laboratory Medicine, University of Padova, Padova, Italy
    Clin Chim Acta 412:1662-7. 2011
    ..We compared the diagnostic accuracy of three new tests proposed for CD screening with that of the well established IgA tTG, and ascertained whether any combination of these tools might enhance accuracy in diagnosing CD...
  56. ncbi request reprint Maldi-TOF analysis of portal sera of pancreatic cancer patients: identification of diabetogenic and antidiabetogenic peptides
    Anna Valerio
    Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
    Clin Chim Acta 343:119-27. 2004
    ....
  57. ncbi request reprint External Quality Assessment: an effective tool for Clinical Governance in laboratory medicine
    Laura Sciacovelli
    Centre of Biomedical Research, Civil Hospital, Castelfranco Veneto TV, and Department of Laboratory Medicine, University Hospital, Padova, Italy
    Clin Chem Lab Med 44:740-9. 2006
    ..The main aim of the activities of an EQAP in Laboratory Medicine is to sustain improvements in the quality of services provided by participating laboratories for the benefit of patients...
  58. doi request reprint VKORC1, CYP2C9 and CYP4F2 genetic-based algorithm for warfarin dosing: an Italian retrospective study
    Carlo Federico Zambon
    Department of Laboratory Medicine, University Hospital of Padua, 35128 Padua, Italy
    Pharmacogenomics 12:15-25. 2011
    ..A total of 371 patients under stable warfarin therapy were retrospectively selected to develop a pharmacogenetic algorithm to identify the individual maintenance dose...
  59. ncbi request reprint Risk management in laboratory medicine: quality assurance programs and professional competence
    Laura Sciacovelli
    Center of Biomedical Research, Castelfranco Veneto, Italy
    Clin Chem Lab Med 45:756-65. 2007
    ..The examples highlight that any well-designed quality system can be ineffective if it is not managed by highly competent professionals with a deep sense of responsibility...
  60. ncbi request reprint Time to reconsider the clinical value of immunoglobulin G4 to foods?
    Daniela Bernardi
    Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy
    Clin Chem Lab Med 46:687-90. 2008
    ..The usefulness of serum antibodies to common food antigens (immunoglobulin G4; IgG4) assay in management of patients suffering from food intolerance was assessed...
  61. ncbi request reprint Helicobacter pylori infection in children and adults: a single pathogen but a different pathology
    Nicoletta Gallo
    Department of Laboratory Medicine, University of Padova, Italy
    Helicobacter 8:21-8. 2003
    ..The aims of this retrospective study were to ascertain in large series of children and adults: the relationship of the infecting strain to gastric mucosal lesions; and the relationship of the infecting strain to its duodenal localization...
  62. ncbi request reprint New biochemical markers: from bench to bedside
    Martina Zaninotto
    Department of Laboratory Medicine, University Hospital of Padova, Italy
    Clin Chim Acta 381:14-20. 2007
    ..However, patients with normal troponin values are not necessarily risk-free for major cardiac events...
  63. doi request reprint The "hospital central laboratory": automation, integration and clinical usefulness
    Martina Zaninotto
    Department of Laboratory Medicine, University Hospital, Padova, Italy
    Clin Chem Lab Med 48:911-7. 2010
    ..In conclusion, in laboratory medicine, technology represents a tool for improving clinical effectiveness and patient outcomes, but it has to be managed by qualified laboratory professionals...
  64. ncbi request reprint Precision performance at low levels and 99th percentile concentration of the Access AccuTnl assay on two different platforms
    Martina Zaninotto
    Department of Laboratory Medicine, University Hospital, Padova, Italy
    Clin Chem Lab Med 47:367-71. 2009
    ....
  65. doi request reprint Evaluation of effectiveness of a computerized notification system for reporting critical values
    Elisa Piva
    Department of Laboratory Medicine, Padua University School of Medicine, Padua, Italy
    Am J Clin Pathol 131:432-41. 2009
    ..The communication also improves the likelihood of reaching the physician on call and may provide important decision support...
  66. doi request reprint The IFCC Working Group on laboratory errors and patient safety
    Laura Sciacovelli
    Center of Biomedical Research, Castelfranco Veneto TV, Italy
    Clin Chim Acta 404:79-85. 2009
    ..The mission of the WG-LEPS is to promote and encourage investigations into errors in laboratory medicine, collect data available on this issue and recommend strategies and procedures for improving patient safety...
  67. pmc Hypoxia inducible factor-1alpha inactivation unveils a link between tumor cell metabolism and hypoxia-induced cell death
    Elena Favaro
    Department of Oncology and Surgical Sciences, Oncology Section, University of Padova, Padova, Italy
    Am J Pathol 173:1186-201. 2008
    ....
  68. doi request reprint Pancreatic cancer alters human CD4+ T lymphocyte function: a piece in the immune evasion puzzle
    Paola Fogar
    Department of Laboratory Medicine, University of Padova, Padova, Italy
    Pancreas 40:1131-7. 2011
    ....
  69. ncbi request reprint H. pylori infection: bacterial virulence factors and cytokine gene polymorphisms as determinants of infection outcome
    Daniela Basso
    Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy
    Crit Rev Clin Lab Sci 41:313-37. 2004
    ..pylori infection. This review focuses on the role of H. pylori virulence genes and on host cytokines' genes polymorphisms in determining clinical outcome to H. pylori infection...
  70. ncbi request reprint In vivo and in vitro allergy diagnostics: it's time to re-appraise the costs
    Franco Borghesan
    Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy
    Clin Chem Lab Med 45:391-5. 2007
    ..The aim of the present paper is to evaluate the relevance of component-resolved in vitro diagnosis in comparison to extract-based diagnosis and the relative global costs in relation to clinical outcomes...
  71. ncbi request reprint Requirements for improving quality in the measurement of bone markers
    Daniela Bernardi
    Department of Laboratory Medicine, University Hospital of Padua, Padua, Italy
    Clin Chim Acta 346:79-86. 2004
    ..The aim of the present study was to define quality specifications of bone markers measurement in the total testing process...
  72. ncbi request reprint Laboratory network of excellence: enhancing patient safety and service effectiveness
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy
    Clin Chem Lab Med 44:150-60. 2006
    ..These data should stimulate debate in the scientific community and encourage more clinical laboratories to use the same indicators to improve clinical effectiveness and clinical outcomes within the healthcare service...
  73. ncbi request reprint Clinical significance of alpha-fetoprotein mRNA in blood of patients with hepatocellular carcinoma
    Umberto Cillo
    Clinica Chirurgica I, Department of Surgical and Gastroenterological Sciences, University of Padua, School of Medicine, Via Giustiniani 2, Policlinico III Piano, 35128 Padova, Italy
    Clin Chim Acta 347:129-38. 2004
    ..The specificity of this molecular marker and its correlation with the main HCC clinical-pathological parameters remains controversial, however...
  74. ncbi request reprint External quality assessment for biochemical markers of myocardial damage: an Italian experience
    Martina Zaninotto
    Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy
    Clin Chem Lab Med 42:1434-41. 2004
    ..The findings demonstrate that participation in EQA schemes provided an opportunity for participating laboratories to continuously improve the quality of their services...
  75. doi request reprint Post-analytical errors with portable glucose meters in the hospital setting
    Paolo Carraro
    Department of Laboratory Medicine, University Hospital of Padova, Italy
    Clin Chim Acta 404:65-7. 2009
    ..2% of results. Although in the post-analytical phase the frequency of incomplete or incorrect data was high, no adverse events were found to be related to this type of error...
  76. doi request reprint Interpretative reports and critical values
    Elisa Piva
    Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy
    Clin Chim Acta 404:52-8. 2009
    ..Clinical laboratories can therefore work to improve clinical effectiveness, without forgetting that everything should be designed to provide the best outcomes for patients...
  77. ncbi request reprint Cytokines and liver failure: modification of TNF- and IL-6 in patients with acute on chronic liver decompensation treated with Molecular Adsorbent Recycling System (MARS)
    Giovanni Ambrosino
    Department of Surgery and Gastroenterological Science, Liver Transplant Unit, University of Padova, Padova, Italy
    Acta Biomed 74:7-9. 2003
    ..The study confirms the efficacy of MARS therapy in terms of homeostasis of the cytokines network and suggests an usefulness of monitoring their level during liver failure...
  78. ncbi request reprint The C-reactive protein levels in left ventricular dysfunction of different etiology
    Dinko Anzulović-Mirosević
    Department of Cardiology, University of Padova Medical School, Padova, Italy
    Inflamm Allergy Drug Targets 8:247-51. 2009
    ..We have investigated variations in the C-reactive protein levels in groups of patients with left ventricular dysfunction of various causes...
  79. ncbi request reprint Fecal lactoferrin and calprotectin after ileocolonic resection for Crohn's disease
    Marco Scarpa
    Clinica Chirurgica I, Dipartimento di Scienze Chirurgiche e Gastroenterologiche, University of Padova, Padova, Italy
    Dis Colon Rectum 50:861-9. 2007
    ..This study was designed to assess the role of fecal lactoferrin and calprotectin as markers of intestinal inflammation in patients with Crohn's disease who have undergone ileocolonic resection...
  80. ncbi request reprint Is osteoporosis a peculiar association with primary biliary cirrhosis?
    Annarosa Floreani
    Div Gastroenterologia, Via Giustiniani, 2, Padova 35128, Italy
    World J Gastroenterol 11:5347-50. 2005
    ....
  81. ncbi request reprint Anti-heparan sulphate antibodies and homocysteine in dementia: markers of vascular pathology?
    Chiara Briani
    Department of Neurosciences, University of Padova, Via Giustiniani, 5, 35128 Padova, Italy
    J Neurol Sci 229:215-8. 2005
    ..2% of patients with other neurological diseases. The present findings suggest that neither elevated HS Abs titres nor increased homocysteinemia may represent a useful biochemical marker for the diagnosis of VD...
  82. ncbi request reprint Pro- and anti-inflammatory cytokines gene polymorphisms and Helicobacter pylori infection: interactions influence outcome
    Carlo F Zambon
    Department of Medical and Surgical Sciences, University of Padua, Via Giustiniani 2, 35128 Padua, Italy
    Cytokine 29:141-52. 2005
    ..In conclusion, among host genetic factors contributing to H. pylori disease outcome, IFN-G +874 AA genotype favors cagA positive infections, TNF-A -857 TT duodenal ulcer while IL-10 -819 TT intestinal metaplasia and NCGC...
  83. doi request reprint Evidence for osteocalcin production by adipose tissue and its role in human metabolism
    Carlo Foresta
    Department of Histology, Internal Medicine 3, University of Padova, Italy
    J Clin Endocrinol Metab 95:3502-6. 2010
    ..The adipose tissue (AT), which is an endocrine organ, is linked to several metabolic abnormalities. Undercarboxylated osteocalcin (ucOCN) regulates insulin and adiponectin secretion...
  84. ncbi request reprint Plasma levels of tumor necrosis factor-alpha correlate with the six-minute walk test results in patients with mild to moderate heart failure
    Giovanni Maria Boffa
    Department of Cardiology, University of Padua Medical School, Italy
    Ital Heart J 5:48-52. 2004
    ..The plasma levels of brain natriuretic peptide, tumor necrosis factor-alpha, big endothelin-1 and cardiac troponins have been reported to correlate with the severity of heart failure...
  85. ncbi request reprint Clinical significance of cytokine determination in synovial fluid
    Leonardo Punzi
    Division of Rheumatology, Department of Medical and Surgical Sciences, University of Padova, Italy
    Crit Rev Clin Lab Sci 39:63-88. 2002
    ..Furthermore, as some of these cytokines may reflect disease activity, their determination may also be useful in the evaluation of therapy...
  86. ncbi request reprint Protein turnover, lipolysis, and endogenous hormonal secretion in critically ill children
    Paola E Cogo
    Department of Pediatrics, Azienda Ospedaliera of Padova, Italy
    Crit Care Med 30:65-70. 2002
    ..We studied whether protein and lipid turnover correlate with insulin and growth and thyroid hormone plasma levels in critically ill infants...
  87. ncbi request reprint Endothelin receptor blockade lowers plasma aldosterone levels via different mechanisms in primary aldosteronism and high-to-normal renin hypertension
    Gian Paolo Rossi
    Department of Clinical and Experimental Medicine, Clinica Medica 4, University Hospital, Via Giustiniani 2, 35126 Padova, Italy
    Cardiovasc Res 57:277-83. 2003
    ..In the rat this latter effect occurs via ET(B) receptors; in humans in vitro studies implicated both ET(A) and ET(B) receptors, but there is no conclusive evidence in vivo...
  88. ncbi request reprint Hepatocyte transplantation in the treatment of acute liver failure: microencapsulated hepatocytes versus hepatocytes attached to an autologous biomatrix
    Giovanni Ambrosino
    Department of Surgical and Gastroenterologic Sciences, Liver Transplant Unit, School of Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Cell Transplant 12:43-9. 2003
    ..PBMHcTx is a useful method to treat acute liver failure and it indicates a possible liver-direct gene therapy in the treatment of inherited and acquired disorders...
  89. ncbi request reprint Tear levels and activity of matrix metalloproteinase (MMP)-1 and MMP-9 in vernal keratoconjunctivitis
    Andrea Leonardi
    Department of Neuroscience, Ophthalmology and Ocular Inflammation Unit, University of Padua, Padua, Italy
    Invest Ophthalmol Vis Sci 44:3052-8. 2003
    ..To study levels and activity of matrix metalloproteinase (MMP)-1 and -9 and their tissue inhibitor (TIMP-1) in tears of patients with vernal keratoconjunctivitis (VKC), with and without severe corneal damage...
  90. ncbi request reprint Cord blood cardiac troponin T and troponin I levels in multiple-gestation neonates
    Daniele Trevisanuto
    Pediatric Department, University of Padova Medical School, Padova, Italy
    Biol Neonate 85:269-72. 2004
    ..These data suggest that myocardial damage, evaluated by cardiac troponin T, troponin I, and creatine kinase MB measurements, does not seem to be a relevant problem in multiple-gestation neonates...
  91. ncbi request reprint Anemia and ischemia: myocardial injury in patients with gastrointestinal bleeding
    Fabio Bellotto
    Department of Clinical Cardiology, Padua General Hospital, University of Padua Medical School, Via Giustiniani 2, 35128 Padua, Italy
    Am J Med 118:548-51. 2005
  92. doi request reprint Mass spectrometry measurement of plasma hepcidin for the prediction of iron overload
    Annarosa Floreani
    Department of Surgical and Gastroenterological Sciences, University of Padova, Padova, Italy
    Clin Chem Lab Med 49:197-206. 2011
    ..The aims of the study were 1) to assess the performance of this method in different conditions of iron metabolism disorders; 2) to assess the diagnostic validity of non-invasive serum biomarkers in the identification of iron overload...
  93. doi request reprint Effects of long-term administration of recombinant human protein C in xenografted primates
    Paolo Simioni
    Department of Cardiologic, Thoracic and Vascular Sciences, 2nd Chair of Internal Medicine, University of Padua, Padua, Italy
    Transplantation 91:161-8. 2011
    ....
  94. ncbi request reprint Correlations between clinical presentation, brain natriuretic peptide, big endothelin-1, tumor necrosis factor-alpha and cardiac troponins in heart failure patients
    Giovanni Maria Boffa
    Department of Cardiology, University of Padua Medical School, Padua, Italy
    Ital Heart J 6:125-32. 2005
    ....
  95. ncbi request reprint Perihepatic adipose tissue thickness: a new non-invasive marker of NAFLD?
    Flavio Lirussi
    Department of Medical and Surgical Sciences University of Padua Medical School, Italy
    J Gastrointestin Liver Dis 18:61-6. 2009
    ..e. the thickness of the fat between the abdominal muscular layer and the hepatic surface, in addition to waist circumference, BMI, biochemistry and serum adipokines, to predict the severity of liver damage in NAFLD...
  96. ncbi request reprint Th1- and Th2-type cytokines in chronic ocular allergy
    Andrea Leonardi
    Department of Neuroscience, Ophthalmology Unit, Via Giustiniani 2, 35128, Padova, Italy
    Graefes Arch Clin Exp Ophthalmol 244:1240-5. 2006
    ..The purpose of this study is to measure levels and mRNA expression of Th1- and Th2-type cytokines in patients with active vernal keratoconjunctivitis (VKC) and atopic keratoconjunctivitis (AKC)...
  97. ncbi request reprint A large deletion due to a new mutation (intron 13/exon 23) in a sporadic case of severe hemophilia A
    Anna Maria Lombardi
    Department of Medical and Surgical Sciences, 2nd Chair of Internal Medicine, University of Padua Medical School, Padua, Italy
    Clin Appl Thromb Hemost 10:61-4. 2004
    ..In the index patient, an approximate 13-kb product was obtained, whereas no product was obtained from his mother. The mother investigated by means of polymorphism was shown not to be a carrier...
  98. ncbi request reprint Case series of 406 vernal keratoconjunctivitis patients: a demographic and epidemiological study
    Andrea Leonardi
    Department of Neuroscience, Clinical Ophthalmology Unit, University of Padua, Padua, Italy
    Acta Ophthalmol Scand 84:406-10. 2006
    ..To evaluate the specific allergic sensitization and epidemiological characteristics of vernal keratoconjunctivitis (VKC)...
  99. ncbi request reprint Establishment and characterization of xenografts and cancer cell cultures derived from BRCA1 -/- epithelial ovarian cancers
    Stefano Indraccolo
    Istituto Oncologico Veneto, Padova, Italy
    Eur J Cancer 42:1475-83. 2006
    ..The PD-OVCA1 and PD-OVCA2 ovarian cancer cell lines will provide a valuable tool for new experimental models for the study of BRCA1-associated tumour biology...
  100. ncbi request reprint The pharmacokinetics and immunosuppressive response of tacrolimus in paediatric renal transplant recipients
    Giovanni Montini
    Nephrology, Dialysis and Transplant Unit, Pediatric Department, University Hospital, Via Giustiniani 3, 35128, Padua, Italy
    Pediatr Nephrol 21:719-24. 2006
    ..Children<6 years old need to start with a 50% higher tacrolimus dose to achieve the same pharmacokinetic and immunosuppressive results...
  101. ncbi request reprint C-reactive protein in hypertensive disorders in pregnancy
    Delia M Paternoster
    Department of Gynecology and Human Reproduction Padova, Italy
    Clin Appl Thromb Hemost 12:330-7. 2006
    ..Finally CRP levels in preeclampsia are believed to correlate with preeclamptic process severity...