Giuseppe De Palma

Summary

Affiliation: University of Brescia
Country: Italy

Publications

  1. ncbi request reprint Metal ions affecting reproduction and development
    Pietro Apostoli
    Department of Experimental and Applied Medicine, Unit of Occupational Medicine and Industrial Hygiene, University of Brescia, P le Spedali Civili, 1, I 25123 Brescia, Italy
    Met Ions Life Sci 8:263-303. 2011
  2. ncbi request reprint [Biological monitoring of exposure to carcinogenic metallic elements and polycyclic aromatic hydrocarbons in four secondary metallurgical sectors]
    G De Palma
    Dipartimento di Medicina Sperimentale ed Applicata, Sezione di Medicina del Lavoro ed Igiene Industriale, Universita degli Studi di Brescia, Brescia, Italy
    G Ital Med Lav Ergon 34:44-7. 2012
  3. ncbi request reprint [Environmental and biological monitoring of exposure to monoaromatic hydrocarbons and to methyl tert-butyl ether in a group of petrol station workers]
    G De Palma
    Dipartimento di Medicina Sperimentale ed Applicata, Sezione di Medicina del Lavoro ed Igiene Industriale, Universita di Brescia, Piazzale Spedali Civili 1, 25123 Brescia
    G Ital Med Lav Ergon 33:49-52. 2011
  4. ncbi request reprint Biological monitoring as a valid tool to assess occupational exposure to mixtures of 2,4-:2,6-toluene diisocyanate
    G De Palma
    Department of Experimental and Applied Medicine, Section of Occupational Health and Industrial Hygiene, University of Brescia, Brescia, Italy
    Med Lav 103:361-71. 2012
  5. doi request reprint Biomarkers of exposure to aromatic hydrocarbons and methyl tert-butyl ether in petrol station workers
    Giuseppe De Palma
    Department of Experimental and Applied Medicine, Occupational Medicine and Industrial Hygiene, University of Brescia, Italy
    Biomarkers 17:343-51. 2012
  6. pmc Metabolism of the EGFR tyrosin kinase inhibitor gefitinib by cytochrome P450 1A1 enzyme in EGFR-wild type non small cell lung cancer cell lines
    Roberta R Alfieri
    Department of Experimental Medicine, Unit of Experimental Oncology, University of Parma, Parma, Italy
    Mol Cancer 10:143. 2011
  7. doi request reprint Lack of correlation between metallic elements analyzed in hair by ICP-MS and autism
    Giuseppe De Palma
    Department of Experimental and Applied Medicine, Section of Occupational Health and Industrial Hygiene, University of Brescia, Piazzale Spedali Civili 1, Brescia, Italy
    J Autism Dev Disord 42:342-53. 2012
  8. ncbi request reprint [New molecular indicators for the prevention of tumor and degenerative diseases: anomalous DNA methylation]
    G De Palma
    Dipartimento di Medicina Sperimentale ed Applicata, Sezione Tossicologia Industriale, Universita degli Studi di Brescia, Italy
    G Ital Med Lav Ergon 31:51-3. 2009
  9. doi request reprint Biological monitoring of tungsten (and cobalt) in workers of a hard metal alloy industry
    Giuseppe De Palma
    Department of Experimental and Applied Medicine, University of Brescia, Italy
    Int Arch Occup Environ Health 83:173-81. 2010
  10. doi request reprint A case-control study of Parkinson's disease and tobacco use: gene-tobacco interactions
    Giuseppe De Palma
    Department of Experimental and Applied Medicine, University of Brescia, Italy
    Mov Disord 25:912-9. 2010

Collaborators

Detail Information

Publications29

  1. ncbi request reprint Metal ions affecting reproduction and development
    Pietro Apostoli
    Department of Experimental and Applied Medicine, Unit of Occupational Medicine and Industrial Hygiene, University of Brescia, P le Spedali Civili, 1, I 25123 Brescia, Italy
    Met Ions Life Sci 8:263-303. 2011
    ..Also, for females the evidences of specific aspects such as fertility or abortions are usually higher and clearer from animal experiments than from human studies...
  2. ncbi request reprint [Biological monitoring of exposure to carcinogenic metallic elements and polycyclic aromatic hydrocarbons in four secondary metallurgical sectors]
    G De Palma
    Dipartimento di Medicina Sperimentale ed Applicata, Sezione di Medicina del Lavoro ed Igiene Industriale, Universita degli Studi di Brescia, Brescia, Italy
    G Ital Med Lav Ergon 34:44-7. 2012
    ..Most of the determinations fell within the laboratory's reference values. Age and lifestyle habits (smoking, alcohol, diet) played a significant interfering role...
  3. ncbi request reprint [Environmental and biological monitoring of exposure to monoaromatic hydrocarbons and to methyl tert-butyl ether in a group of petrol station workers]
    G De Palma
    Dipartimento di Medicina Sperimentale ed Applicata, Sezione di Medicina del Lavoro ed Igiene Industriale, Universita di Brescia, Piazzale Spedali Civili 1, 25123 Brescia
    G Ital Med Lav Ergon 33:49-52. 2011
    ..U-MTBE levels were strictly influenced by occupational exposure to gasoline, whereas both U-B and S-PMA levels depended from smoking habits and occupational exposure...
  4. ncbi request reprint Biological monitoring as a valid tool to assess occupational exposure to mixtures of 2,4-:2,6-toluene diisocyanate
    G De Palma
    Department of Experimental and Applied Medicine, Section of Occupational Health and Industrial Hygiene, University of Brescia, Brescia, Italy
    Med Lav 103:361-71. 2012
    ..The present study was designed in order to evaluate the feasibility and reliability of biological monitoring in a factory producing polyurethane foam blocks...
  5. doi request reprint Biomarkers of exposure to aromatic hydrocarbons and methyl tert-butyl ether in petrol station workers
    Giuseppe De Palma
    Department of Experimental and Applied Medicine, Occupational Medicine and Industrial Hygiene, University of Brescia, Italy
    Biomarkers 17:343-51. 2012
    ..Linear regression confirmed that occupational exposure was a main predictor of U-MTBE, U-B and S-PMA values, both the latter confounded by smoking habits. The study supports the usefulness of biomonitoring even at low exposure levels...
  6. pmc Metabolism of the EGFR tyrosin kinase inhibitor gefitinib by cytochrome P450 1A1 enzyme in EGFR-wild type non small cell lung cancer cell lines
    Roberta R Alfieri
    Department of Experimental Medicine, Unit of Experimental Oncology, University of Parma, Parma, Italy
    Mol Cancer 10:143. 2011
    ..The primary site of gefitinib metabolism is the liver, nevertheless tumor cell metabolism can significantly affect treatment effectiveness...
  7. doi request reprint Lack of correlation between metallic elements analyzed in hair by ICP-MS and autism
    Giuseppe De Palma
    Department of Experimental and Applied Medicine, Section of Occupational Health and Industrial Hygiene, University of Brescia, Piazzale Spedali Civili 1, Brescia, Italy
    J Autism Dev Disord 42:342-53. 2012
    ..A slight association was found for lead only, but it was very weak, as strictly dependent on the worst data from one study...
  8. ncbi request reprint [New molecular indicators for the prevention of tumor and degenerative diseases: anomalous DNA methylation]
    G De Palma
    Dipartimento di Medicina Sperimentale ed Applicata, Sezione Tossicologia Industriale, Universita degli Studi di Brescia, Italy
    G Ital Med Lav Ergon 31:51-3. 2009
    ..The characterization of DNA methylation abnormalities by modern molecular biology methods may allow the development of new molecular biomarkers of early biological effects...
  9. doi request reprint Biological monitoring of tungsten (and cobalt) in workers of a hard metal alloy industry
    Giuseppe De Palma
    Department of Experimental and Applied Medicine, University of Brescia, Italy
    Int Arch Occup Environ Health 83:173-81. 2010
    ..To evaluate a combined biomonitoring approach based on both cobalt and tungsten determination in workers of the hard metal alloy sector...
  10. doi request reprint A case-control study of Parkinson's disease and tobacco use: gene-tobacco interactions
    Giuseppe De Palma
    Department of Experimental and Applied Medicine, University of Brescia, Italy
    Mov Disord 25:912-9. 2010
    ..Owing to the retrospective design of the study, these results require confirmation...
  11. ncbi request reprint Metallic elements in pulmonary biopsies from lung cancer and control subjects
    Giuseppe De Palma
    Department of Experimental and Applied Medicine, Section of Industrial Hygiene, University of Brescia, Brescia, Italy
    Acta Biomed 79:43-51. 2008
    ..The role of past environmental-occupational exposures could not be fully elucidated, due to the limited sample size and the retrospective nature of the study...
  12. doi request reprint Toxicokinetics and toxicodynamics of elemental mercury following self-administration
    Giuseppe De Palma
    Department of Experimental and Applied Medicine, Section of Industrial Hygiene, University of Brescia, Brescia, Italy
    Clin Toxicol (Phila) 46:869-76. 2008
    ..Intravenous injection of mercury has seldom been reported, especially in cases of attempted suicide, and is associated with variable clinical outcomes...
  13. doi request reprint Persistent organochlorine compounds in fetal and maternal tissues: evaluation of their potential influence on several indicators of fetal growth and health
    Roberto Bergonzi
    Department of Experimental and Applied Medicine, Section of Occupational Health and Industrial Hygiene, University of Brescia, Viale Europa 11, 25123 Brescia, Italy
    Sci Total Environ 409:2888-93. 2011
    ..Mothers of neonates born by preterm programmed caesarean delivery showed significantly (p<0.005 for both) higher serum p,p'-DDE serum concentrations and p,p'-DDT levels in the adipose tissue, as compared to mothers delivering at term...
  14. doi request reprint Lack of correlation between blood lead and serum prolactin levels among lead exposed workers
    Simona Catalani
    Department of Experimental and Applied Medicine, Section of Industrial Hygiene, University of Brescia, Brescia, Italy
    Biomarkers 17:513-9. 2012
    ..The results do not support a routine use of S-PRL as a biomarker of effect in lead exposed workers...
  15. ncbi request reprint [Biomarkers of effect and susceptibility to low doses of benzene]
    Giuseppe De Palma
    Dipartimento di Specialità Medico Chirurgiche, Scienze Radiologiche e Sanità Pubblica, Sezione Sanità Pubblica e Scienze Umane, Universita degli Studi di Brescia, Brescia, Italy
    G Ital Med Lav Ergon 35:259-62. 2013
    ....
  16. doi request reprint Evaluation of different methods to determine total serum lipids for normalization of circulating organochlorine compounds
    Roberto Bergonzi
    Department of Experimental and Applied Medicine, Section of Occupational Health and Industrial Hygiene, University of Brescia, Brescia, Italy
    Int Arch Occup Environ Health 82:1241-7. 2009
    ..The study was aimed at: (i) evaluating the validity of these formulae; (ii) evaluating the influence of different estimates on serum levels of lipid adjusted persistent organochlorine compounds...
  17. ncbi request reprint [Classification as carcinogenic for 2,3,7,8-tetrachlorodibenzo-para-dioxin: an eventful journey]
    Pietro Apostoli
    Dipartimento di Medicina Sperimentale e Applicata, Sezione di Medicina del Lavoro e Igiene Industriale, Universita degli Studi di Brescia, Italy
    G Ital Med Lav Ergon 33:84-99. 2011
    ..In this paper a literature review accompanied by comments is reported with the aim to provide information about the evaluation process and tools for its more critical and scrupulous interpretation...
  18. ncbi request reprint [Polychlorinated dibenzofurans and cancer]
    Pietro Apostoli
    Dipartimento di Medicina Sperimentale e Applicata, Sezione di Medicina del Lavoro e Igiene Industriale, Universita degli Studi di Brescia, Italy
    G Ital Med Lav Ergon 33:185-92. 2011
    ..The PCDF as a group may be therefore classified at limited evidence of carcinogenicity. This paper concludes the cycle of review about other POPs, i.e. dioxins and PCBs...
  19. ncbi request reprint [Environmental monitoring of volatile organic compounds and metallic elements in two analysis laboratories]
    Roberto Bergonzi
    Dipartimento di Medicina Sperimentale ed Applicata, Sezione di Medicina del Lavoro e Igiene Industriale, Universita degli Studi di Brescia, Italy
    G Ital Med Lav Ergon 33:387-93. 2011
    ..The determination of measurable levels of toxic and potentially carcinogenic compounds in office rooms may be of interest for personnel not specifically engaged to handle chemicals...
  20. ncbi request reprint Metallic elements in lung tissues: results of a meta-analysis
    Simona Catalani
    Department of Experimental and Applied Medicine, Section of Occupational Health and Industrial Hygiene, University of Brescia, Brescia, Italy
    Acta Biomed 79:52-63. 2008
    ..Such a variability of measures, combined with the very low metal concentrations calls for the definition and use of standardized procedures of sample collection, storage, and analysis...
  21. ncbi request reprint Endogenous thiols and MRP transporters contribute to Hg2+ efflux in HgCl2-treated tubular MDCK cells
    Maria Francesca Aleo
    Unit of Biochemistry, Department of Biomedical Sciences and Biotechnologies, School of Medicine, University of Brescia, Viale Europa, 11, 25123 Brescia, Italy
    Toxicology 206:137-51. 2005
    ..Our results demonstrate that, in MDCK cells, inorganic Hg(2+) promotes the activation of specific detoxifying pathways that may, at least partly, depend on the activity of MRP transporters...
  22. ncbi request reprint Exposure to polychlorinated biphenyls in residents near a chemical factory in Italy: the food chain as main source of contamination
    Francesco Donato
    Institute of Hygiene, Epidemiology and Public Health, Universita di Brescia, Facolta di Medicina e Chirurgia, Viale Europa 11, 25123 Brescia, Italy
    Chemosphere 64:1562-72. 2006
    ..In conclusion, we found high serum PCB levels in humans living in a highly polluted area in an industrialized town in Italy, due mainly to consumption of food produced in polluted areas...
  23. doi request reprint Stress proteins and oxidative damage in a renal derived cell line exposed to inorganic mercury and lead
    Alessandra Stacchiotti
    Human Anatomy Unit, Department of Biomedical Sciences and Biotechnology, School of Medicine, University of Brescia, Italy
    Toxicology 264:215-24. 2009
    ..Indeed, different chaperones are involved in the specific nephrotoxic mechanism of these environmental pollutants and work together for cell survival...
  24. ncbi request reprint Elements in environmental and occupational medicine
    Pietro Apostoli
    Institute of Occupational Medicine and Industrial Hygiene, University of Brescia, Brescia, Italy
    J Chromatogr B Analyt Technol Biomed Life Sci 778:63-97. 2002
    ....
  25. ncbi request reprint Multielemental analysis of tissues from Cangrande della Scala, Prince of Verona, in the 14th century
    Pietro Apostoli
    Department of Experimental and Applied Medicine, Section of Occupational Health and Industrial Hygiene, University of Brescia, Brescia, Italy
    J Anal Toxicol 33:322-7. 2009
    ..The low arsenic and chromium levels in the Prince's tissues as compared to modern people would be suggestive of raised concentrations of both the elements in the present era, which are likely due to industrial pollution...
  26. doi request reprint Distribution of persistent organochlorine pollutants in maternal and foetal tissues: data from an Italian polluted urban area
    Roberto Bergonzi
    Department of Experimental and Applied Medicine, Section of Occupational Health and Industrial Hygiene, University of Brescia, Viale Europa 11, 25123 Brescia, Italy
    Chemosphere 76:747-54. 2009
    ..Maternal serum levels of these pollutants can allow a reliable estimation of organochlorine compound body burden, and can be useful markers of prenatal exposure, given their relationships with placental and umbilical cord serum levels...
  27. doi request reprint Polychlorinated biphenyls and thyroid hormone serum concentrations among people living in a highly polluted area: a cross-sectional population-based study
    Francesco Donato
    Department of Experimental and Applied Medicine, Institute of Hygiene, Epidemiology and Public Health, University of Brescia, Viale Europa 11, Brescia, Italy
    Environ Res 108:380-6. 2008
    ..Polychlorinated biphenyls (PCBs) may interact with several thyroid functions. Severe environmental pollution by PCBs has been observed in Brescia, Italy, due to the presence of a factory that produced these compounds until 1984...
  28. pmc The role of albumin in human toxicology of cobalt: contribution from a clinical case
    Simona Catalani
    Section of Occupational Health and Industrial Hygiene, Department of Experimental and Applied Medicine, University of Brescia, p le Spedali Civili 1, 25123 Brescia, Italy
    ISRN Hematol 2011:690620. 2011
    ..This appears an interesting starting point for further investigations for identifying and better understanding cobalt neurotoxicity, apparently not so frequent in occupational medicine and clinical practice...
  29. ncbi request reprint Focal adhesion molecules as potential target of lead toxicity in NRK-52E cell line
    Roberta Giuliani
    Unit of Biochemistry, School of Medicine, University of Brescia, Italy
    FEBS Lett 579:6251-8. 2005
    ..These effects appeared to be strictly associated to the Pb-induced arrest of cell cycle at G0/G1 phase also proved in this cell line...