Giuseppe De Luca

Summary

Affiliation: University of Piemonte Orientale
Country: Italy

Publications

  1. ncbi Short-term effects of aspirin and clopidogrel on mean platelet volume among patients with acute coronary syndromes. A single-center prospective study
    Giuseppe De Luca
    Division of Cardiology, Maggiore della Carita Hospital, University of Eastern Piedmont, Novara, Italy
    Blood Coagul Fibrinolysis 23:756-9. 2012
  2. ncbi Impact of multivessel disease on myocardial perfusion and survival among patients undergoing primary percutaneous coronary intervention with glycoprotein IIb/IIIa inhibitors
    Giuseppe De Luca
    Division of Cardiology, Maggiore della Carita Hospital, Eastern Piedmont University, Novara, Italy Electronic address
    Arch Cardiovasc Dis 106:155-61. 2013
  3. ncbi Impact of Diabetes on Long-Term Outcome After Primary Angioplasty: Insights from the DESERT cooperation
    Giuseppe De Luca
    Corresponding author Giuseppe De Luca
    Diabetes Care 36:1020-5. 2013
  4. ncbi Preinfarction angina does not affect infarct size in STEMI patients undergoing primary angioplasty
    Giuseppe De Luca
    Division of Cardiology, Maggiore della Carita Hospital, Eastern Piedmont University, 28100 Novara, Italy
    Atherosclerosis 226:153-6. 2013
  5. ncbi Evaluation of intracoronary adenosine to prevent periprocedural myonecrosis in elective percutaneous coronary intervention (from the PREVENT-ICARUS Trial)
    Giuseppe De Luca
    Division of Cardiology, Azienda Ospedaliera Universitaria Maggiore Della Carità, Eastern Piedmont University, Novara, Italy
    Am J Cardiol 109:202-7. 2012
  6. ncbi Glycoprotein IIb-IIIa inhibitors
    Giuseppe De Luca
    Division of Cardiology, Maggiore della Carita Hospital, Universita del Piemonte Orientale A Avogadro, Novara, Italy
    Cardiovasc Ther 30:e242-54. 2012
  7. ncbi Time-related impact of distal embolisation on myocardial perfusion and survival among patients undergoing primary angioplasty with glycoprotein IIb-IIIa inhibitors: insights from the EGYPT cooperation
    Giuseppe De Luca
    Division of Cardiology, Maggiore della Carita Hospital, Eastern Piedmont University, Novara, Italy
    EuroIntervention 8:470-6. 2012
  8. ncbi Benefits from intracoronary as compared to intravenous abciximab administration for STEMI patients undergoing primary angioplasty: a meta-analysis of 8 randomized trials
    Giuseppe De Luca
    Division of Cardiology, Maggiore della Carita Hospital, Universita del Piemonte Orientale, Novara, Italy
    Atherosclerosis 222:426-33. 2012
  9. ncbi Drug-eluting vs bare-metal stents in primary angioplasty: a pooled patient-level meta-analysis of randomized trials
    Giuseppe De Luca
    Division of Cardiology, Ospedale Maggiore della Carita, Eastern Piedmont University, Novara, Italy
    Arch Intern Med 172:611-21; discussion 621-2. 2012
  10. ncbi Uric acid does not affect the prevalence and extent of coronary artery disease. Results from a prospective study
    G De Luca
    1st Division of Cardiology, Division of Neurology, Azienda Ospedaliera Universitaria Maggiore Della Carità, Eastern Piedmont University, Novara, Italy
    Nutr Metab Cardiovasc Dis 22:426-33. 2012

Detail Information

Publications105 found, 100 shown here

  1. ncbi Short-term effects of aspirin and clopidogrel on mean platelet volume among patients with acute coronary syndromes. A single-center prospective study
    Giuseppe De Luca
    Division of Cardiology, Maggiore della Carita Hospital, University of Eastern Piedmont, Novara, Italy
    Blood Coagul Fibrinolysis 23:756-9. 2012
    ..Thus, larger MPV does not imply higher platelet reactivity and may not be considered to monitor platelet reactivity and the efficacy of antiplatelet therapies...
  2. ncbi Impact of multivessel disease on myocardial perfusion and survival among patients undergoing primary percutaneous coronary intervention with glycoprotein IIb/IIIa inhibitors
    Giuseppe De Luca
    Division of Cardiology, Maggiore della Carita Hospital, Eastern Piedmont University, Novara, Italy Electronic address
    Arch Cardiovasc Dis 106:155-61. 2013
    ..The influence of multivessel disease on myocardial reperfusion and survival after primary angioplasty has not been extensively investigated...
  3. ncbi Impact of Diabetes on Long-Term Outcome After Primary Angioplasty: Insights from the DESERT cooperation
    Giuseppe De Luca
    Corresponding author Giuseppe De Luca
    Diabetes Care 36:1020-5. 2013
    ..DES implantation, however, does mitigate the known deleterious effect of diabetes on TVR after BMS...
  4. ncbi Preinfarction angina does not affect infarct size in STEMI patients undergoing primary angioplasty
    Giuseppe De Luca
    Division of Cardiology, Maggiore della Carita Hospital, Eastern Piedmont University, 28100 Novara, Italy
    Atherosclerosis 226:153-6. 2013
    ..Therefore, the aim of the current study was to evaluate the impact of preinfarction angina on scintigraphic infarct size in STEMI patients undergoing primary PCI...
  5. ncbi Evaluation of intracoronary adenosine to prevent periprocedural myonecrosis in elective percutaneous coronary intervention (from the PREVENT-ICARUS Trial)
    Giuseppe De Luca
    Division of Cardiology, Azienda Ospedaliera Universitaria Maggiore Della Carità, Eastern Piedmont University, Novara, Italy
    Am J Cardiol 109:202-7. 2012
    ..In conclusion, our randomized trial showed that preprocedural intracoronary administration of a single high-dose bolus of adenosine does not provide any benefit in terms of periprocedural myonecrosis in patients undergoing elective PCI...
  6. ncbi Glycoprotein IIb-IIIa inhibitors
    Giuseppe De Luca
    Division of Cardiology, Maggiore della Carita Hospital, Universita del Piemonte Orientale A Avogadro, Novara, Italy
    Cardiovasc Ther 30:e242-54. 2012
    ....
  7. ncbi Time-related impact of distal embolisation on myocardial perfusion and survival among patients undergoing primary angioplasty with glycoprotein IIb-IIIa inhibitors: insights from the EGYPT cooperation
    Giuseppe De Luca
    Division of Cardiology, Maggiore della Carita Hospital, Eastern Piedmont University, Novara, Italy
    EuroIntervention 8:470-6. 2012
    ....
  8. ncbi Benefits from intracoronary as compared to intravenous abciximab administration for STEMI patients undergoing primary angioplasty: a meta-analysis of 8 randomized trials
    Giuseppe De Luca
    Division of Cardiology, Maggiore della Carita Hospital, Universita del Piemonte Orientale, Novara, Italy
    Atherosclerosis 222:426-33. 2012
    ..Therefore, the aim of the current study was to perform a meta-analysis of randomized trials (RCTs) to assess the clinical efficacy and safety of IC vs IV abciximab administration in STEMI patients undergoing primary angioplasty...
  9. ncbi Drug-eluting vs bare-metal stents in primary angioplasty: a pooled patient-level meta-analysis of randomized trials
    Giuseppe De Luca
    Division of Cardiology, Ospedale Maggiore della Carita, Eastern Piedmont University, Novara, Italy
    Arch Intern Med 172:611-21; discussion 621-2. 2012
    ....
  10. ncbi Uric acid does not affect the prevalence and extent of coronary artery disease. Results from a prospective study
    G De Luca
    1st Division of Cardiology, Division of Neurology, Azienda Ospedaliera Universitaria Maggiore Della Carità, Eastern Piedmont University, Novara, Italy
    Nutr Metab Cardiovasc Dis 22:426-33. 2012
    ..Thus, the aim of the current study was to investigate in a consecutive cohort of patients undergoing coronary angiography whether hyperuricemia is associated with the extent of coronary artery disease...
  11. ncbi Transferring patients with ST-segment elevation myocardial infarction for mechanical reperfusion: a meta-regression analysis of randomized trials
    Giuseppe De Luca
    Division of Cardiology, Maggiore della Carita Hospital, Eastern Piedmont University A Avogadro, Novara, Italy
    Ann Emerg Med 52:665-76. 2008
    ....
  12. ncbi Benefits of pharmacological facilitation with glycoprotein IIb-IIIa inhibitors in diabetic patients undergoing primary angioplasty for STEMI. A subanalysis of the EGYPT cooperation
    Giuseppe De Luca
    Division of Cardiology Maggiore della Carità, Hospital, Eastern Piedmont University, Novara, Italy
    J Thromb Thrombolysis 28:288-98. 2009
    ....
  13. ncbi Primary angioplasty vs. thrombolysis
    Giuseppe De Luca
    Division of Cardiology, Ospedale Maggiore della Carita, Universita del Piemonte Orientale A Avogadro, Novara, Italy
    Indian Heart J 59:302-10. 2007
    ....
  14. ncbi Short and long-term benefits of sirolimus-eluting stent in ST-segment elevation myocardial infarction: a meta-analysis of randomized trials
    Giuseppe De Luca
    Division of Cardiology, Ospedale Maggiore della Carita, Eastern Piedmont University, Novara, Italy
    J Thromb Thrombolysis 28:200-10. 2009
    ..The aim of the current study was to perform a meta-analysis to evaluate the benefits and safety of Sirolimus-Eluting Stent (SES) as compared to BMS in patients undergoing primary angioplasty for STEMI...
  15. ncbi Benefits from small molecule administration as compared with abciximab among patients with ST-segment elevation myocardial infarction treated with primary angioplasty: a meta-analysis
    Giuseppe De Luca
    Division of Cardiology, Maggiore della Carita Hospital, Eastern Piedmont University A Avogadro, Novara, Italy
    J Am Coll Cardiol 53:1668-73. 2009
    ..The aim of the study was to perform a meta-analysis of randomized trials (RTs) comparing abciximab versus small molecules (eptifibatide and tirofiban) in primary angioplasty (PPCI) for ST-segment elevation myocardial infarction (STEMI)...
  16. ncbi Safety and benefits of protamine administration to revert anticoagulation soon after coronary angioplasty. A meta-analysis
    Giuseppe De Luca
    Division of Cardiology, Chief Interventional Cardiology, Maggiore della Carita Hospital, Eastern Piedmont University A Avogadro, Novara, Italy
    J Thromb Thrombolysis 30:452-8. 2010
    ..Pending the results of larger randomized trials, its use may be considered after coronary angioplasty...
  17. ncbi Antithrombotic therapies in primary angioplasty: rationale, results and future directions
    Giuseppe De Luca
    Division of Cardiology, Maggiore della Carita Hospital, Eastern Piedmont University A Avogadro, Novara, Italy
    Drugs 68:2325-44. 2008
    ....
  18. ncbi Adjunctive manual thrombectomy improves myocardial perfusion and mortality in patients undergoing primary percutaneous coronary intervention for ST-elevation myocardial infarction: a meta-analysis of randomized trials
    Giuseppe De Luca
    Division of Cardiology, Maggiore della Carita Hospital, Eastern Piedmont University, Novara, Italy
    Eur Heart J 29:3002-10. 2008
    ..The aim of the current study was to perform an updated meta-analysis of randomized trials conducted with adjunctive manual thrombectomy devices to prevent distal embolization in AMI...
  19. ncbi Advances in antithrombotic therapy as adjunct to reperfusion therapies for ST-segment elevation myocardial infarction
    Giuseppe De Luca
    Division of Cardiology, Maggiore della Carita Hospital, Eastern Piedmont University A Avogadro, Novara, Italy
    Thromb Haemost 100:184-95. 2008
    ..Thus, additional endpoints, such as infarct size and myocardial perfusion, may be considered in future randomized trials among patients undergoing mechanical revascularization for STEMI...
  20. ncbi Impact of duration of clopidogrel prescription on outcome of DES as compared to BMS in primary angioplasty: a meta-regression analysis of randomized trials
    Giuseppe De Luca
    Division of Cardiology, Ospedale Maggiore della Carita, Eastern Piedmont University, C so Mazzini, 18, 24100 Novara, Italy
    J Thromb Thrombolysis 27:365-78. 2009
    ....
  21. ncbi Early glycoprotein IIb-IIIa inhibitors in primary angioplasty (EGYPT) cooperation: an individual patient data meta-analysis
    G De Luca
    Division of Cardiology, Maggiore della Carita Hospital, Eastern Piedmont University, Novara, Italy
    Heart 94:1548-58. 2008
    ..The aim of this meta-analysis was to combine individual data from all randomised trials conducted on facilitated primary angioplasty by the use of early Gp IIb-IIIa inhibitors...
  22. ncbi Reperfusion strategies in acute ST-elevation myocardial infarction: an overview of current status
    Giuseppe De Luca
    Division of Cardiology, Ospedale Maggiore della Carita, Eastern Piedmont University A Avogadro, Novara, Italy
    Prog Cardiovasc Dis 50:352-82. 2008
    ..However, because of unpredictable compliance to long-term double oral antiplatelet therapy in acute patients, caution should be taken with extensive use of drug-eluting stents in primary angioplasty...
  23. ncbi Adjunctive benefits from low-molecular-weight heparins as compared to unfractionated heparin among patients with ST-segment elevation myocardial infarction treated with thrombolysis. A meta-analysis of the randomized trials
    Giuseppe De Luca
    Division of Cardiology, Maggiore della Carita Hospital, Eastern Piedmont University A Avogadro, Novara, Italy
    Am Heart J 154:1085.e1-6. 2007
    ..The aim of the current study was to perform an updated meta-analysis of all randomized trials comparing low-molecular-weight heparins (LMWHs) versus unfractionated heparin (UFH) in patients with STEMI treated with thrombolysis...
  24. ncbi Mean platelet volume and the extent of coronary artery disease: results from a large prospective study
    Giuseppe De Luca
    Division of Cardiology, Azienda Ospedaliera Universitaria Maggiore Della Carità, Eastern Piedmont University, Corso Mazzini 18, Novara, Italy
    Atherosclerosis 206:292-7. 2009
    ..The aim of the current study was to investigate whether mean platelet volume is associated with the extent of coronary artery disease...
  25. ncbi Diabetes mellitus is associated with distal embolization, impaired myocardial perfusion, and higher mortality in patients with ST-segment elevation myocardial infarction treated with primary angioplasty and glycoprotein IIb-IIIa inhibitors
    Giuseppe De Luca
    Division of Cardiology, Maggiore della Carita Hospital, Eastern Piedmont University, Novara, Italy
    Atherosclerosis 207:181-5. 2009
    ..The aim of the current study was to investigate the impact of diabetes on myocardial perfusion and mortality among STEMI patients treated with primary angioplasty and glycoprotein IIb-IIIa inhibitors...
  26. ncbi Bivalirudin as compared to unfractionated heparin among patients undergoing coronary angioplasty: A meta-analyis of randomised trials
    Giuseppe De Luca
    Chief Interventional Cardiology, Maggiore della Carita Hospital, Eastern Piedmont University A Avogadro, Novara, Italy
    Thromb Haemost 102:428-36. 2009
    ..However, these benefits did not translate into benefits in mortality, with even a trend in higher risk of myocardial infarction...
  27. ncbi Meta-analysis of randomized trials of glycoprotein IIb/IIIa inhibitors in high-risk acute coronary syndromes patients undergoing invasive strategy
    Giuseppe De Luca
    Maggiore della Carita Hospital, Eastern Piedmont University A Avogadro, Novara, Italy
    Am J Cardiol 107:198-203. 2011
    ..Therefore, a strategy of upstream Gp IIb/IIIa inhibitors cannot be recommended...
  28. ncbi High fibrinogen level is an independent predictor of presence and extent of coronary artery disease among Italian population
    Giuseppe De Luca
    Division of Cardiology, Azienda Ospedaliera Universitaria Maggiore Della Carità, Eastern Piedmont University, C so Mazzini, 18, 28100 Novara, Italy
    J Thromb Thrombolysis 31:458-63. 2011
    ..046). This study showed that high fibrinogen level is significantly associated with CAD and carotid atherosclerosis...
  29. ncbi Platelet-large cell ratio and the extent of coronary artery disease: results from a large prospective study
    Giuseppe De Luca
    Division of Cardiology, Azienda Ospedaliera Universitaria Maggiore Della Carità, Eastern Piedmont University, C so Mazzini, 18, 28100 Novara, Italy
    J Thromb Thrombolysis 30:426-33. 2010
    ..This study showed that P-LCR is not related to platelet aggregation, aspirin resistance, the extent of CAD and carotid IMT. Thus, P-LCR can not be considered as a marker of platelet reactivity or a risk factor for CAD...
  30. ncbi Platelet distribution width and the extent of coronary artery disease: results from a large prospective study
    Giuseppe De Luca
    Division of Cardiology, Azienda Ospedaliera Universitaria Maggiore Della Carità, Eastern Piedmont University, Novara, Italy
    Platelets 21:508-14. 2010
    ..04; p = 0.46; Maximal IMT: r = 0.036, p = 0.49). This study showed that PDW is not related to the extent of CAD and carotid IMT. Thus, PDW can not be considered as a risk factor for CAD...
  31. ncbi Thrombectomy during primary angioplasty: methods, devices, and clinical trial data
    Giuseppe De Luca
    Division of Cardiology, Maggiore della Carita Hospital, Eastern Piedmont University A Avogadro, Novara, Italy
    Curr Cardiol Rep 12:422-8. 2010
    ....
  32. ncbi Gender-related differences in outcome after ST-segment elevation myocardial infarction treated by primary angioplasty and glycoprotein IIb-IIIa inhibitors: insights from the EGYPT cooperation
    Giuseppe De Luca
    Division of Cardiology, Maggiore della Carita Hospital, Eastern Piedmont University, Novara, Italy
    J Thromb Thrombolysis 30:342-6. 2010
    ..In fact, female sex did not emerge as an independent predictor of mortality...
  33. ncbi Impact of diabetes on survival in patients with ST-segment elevation myocardial infarction treated by primary angioplasty: insights from the POLISH STEMI registry
    Giuseppe De Luca
    Division of Cardiology, Maggiore della Carita Hospital, Eastern Piedmont University, Novara, Italy
    Atherosclerosis 210:516-20. 2010
    ..The aim of this study was to investigate in a large cohort of patients the impact of diabetes on mortality in a large cohort of patients with STEMI treated with primary angioplasty...
  34. ncbi Impact of distal embolization on myocardial perfusion and survival among patients undergoing primary angioplasty with glycoprotein IIb-IIIa inhibitors: insights from the EGYPT cooperation
    Giuseppe De Luca
    Division of Cardiology, Maggiore della Carita Hospital, Eastern Piedmont University, Novara, Italy
    J Thromb Thrombolysis 30:23-8. 2010
    ..23 [1.1-4.7], P = 0.026). This study showed among STEMI patients treated with Gp IIb-IIIa inhibitors, that distal embolization is independently associated with impaired myocardial perfusion and survival...
  35. ncbi Impact of diabetes on long-term outcome in STEMI patients undergoing primary angioplasty with glycoprotein IIb-IIIa inhibitors and BMS or DES
    Giuseppe De Luca
    Division of Cardiology, Ospedale Maggiore della Carita, Eastern Piedmont University, Cso Mazzini 18, 28100 Novara, Italy
    J Thromb Thrombolysis 30:133-41. 2010
    ....
  36. ncbi Risk profile and benefits from Gp IIb-IIIa inhibitors among patients with ST-segment elevation myocardial infarction treated with primary angioplasty: a meta-regression analysis of randomized trials
    Giuseppe De Luca
    Division of Cardiology, Maggiore della Carita Hospital, Eastern Piedmont University A Avogadro, Novara, Italy
    Eur Heart J 30:2705-13. 2009
    ....
  37. ncbi Percutaneous coronary intervention-related time delay, patient's risk profile, and survival benefits of primary angioplasty vs lytic therapy in ST-segment elevation myocardial infarction
    Giuseppe De Luca
    Division of Cardiology, Ospedale Maggiore della Carita, Eastern Piedmont University, 28100 Novara, Italy
    Am J Emerg Med 27:712-9. 2009
    ..Thus, the aim of the current review is to assess whether the prognostic impact of PCI-related time delay may vary according to patient's risk profile, presentation delay, and type of lytic therapy...
  38. ncbi Facilitated angioplasty with combo therapy among patients with ST-segment elevation myocardial infarction: a meta-analysis of randomized trials
    Giuseppe De Luca
    Division of Cardiology, Maggiore della Carita Hospital, Eastern Piedmont University A Avogadro, Novara, Italy
    Am J Emerg Med 27:683-90. 2009
    ....
  39. ncbi Coronary stenting versus balloon angioplasty for acute myocardial infarction: a meta-regression analysis of randomized trials
    Giuseppe De Luca
    Division of Cardiology, Maggiore della Carita Hospital, Eastern Piedmont University, C so Mazzini, 18, 24100 Novara, Italy
    Int J Cardiol 126:37-44. 2008
    ....
  40. ncbi Association between advanced Killip class at presentation and impaired myocardial perfusion among patients with ST-segment elevation myocardial infarction treated with primary angioplasty and adjunctive glycoprotein IIb-IIIa inhibitors
    Giuseppe De Luca
    Division of Cardiology, Maggiore della Carita Hospital, Eastern Piedmont University, Novara, Italy
    Am Heart J 158:416-21. 2009
    ....
  41. ncbi Effects of increasing doses of intracoronary adenosine on the assessment of fractional flow reserve
    Giuseppe De Luca
    Division of Cardiology, Ospedale Maggiore della Carita, Eastern Piedmont University, Novara, Italy
    JACC Cardiovasc Interv 4:1079-84. 2011
    ..The purpose of this study was to investigate the effects of increasing dose of intracoronary adenosine on fractional flow reserve (FFR) measurement...
  42. ncbi The PASEO (PaclitAxel or Sirolimus-Eluting Stent Versus Bare Metal Stent in Primary Angioplasty) Randomized Trial
    Emilio Di Lorenzo
    Division of Cardiology, Ospedale SG Moscati, Avellino, Italy
    JACC Cardiovasc Interv 2:515-23. 2009
    ..The aim of this study was to evaluate the benefits of sirolimus-eluting stents (SES) and paclitaxel-eluting stents (PES) as compared with bare-metal stents (BMS) in patients undergoing primary angioplasty...
  43. ncbi Impact of preprocedural TIMI flow on myocardial perfusion, distal embolization and mortality in patients with ST-segment elevation myocardial infarction treated by primary angioplasty and glycoprotein IIb/IIIa inhibitors
    Mauro Maioli
    Division of Cardiology, Prato Hospital, Prato, Italy
    J Invasive Cardiol 24:324-7. 2012
    ..The aim of the current study was to evaluate the impact of preprocedural TIMI flow on myocardial perfusion, distal embolization, and survival among STEMI patients undergoing primary angioplasty with glycoprotein (GP) IIb/IIIa inhibitors...
  44. ncbi Long-Term outcome of drug-eluting stents compared with bare metal stents in ST-segment elevation myocardial infarction: results of the paclitaxel- or sirolimus-eluting stent versus bare metal stent in Primary Angioplasty (PASEO) Randomized Trial
    Emilio Di Lorenzo
    Division of Cardiology, Laboratory of Cardiac Catheterization and Interventional Cardiology, S G Moscati Hospital, Via Otranto, Avellino 83100, Italy
    Circulation 120:964-72. 2009
    ..Thus, the aim of the present study was to evaluate the short- and long-term benefits of sirolimus-eluting stents (SES) and paclitaxel-eluting stents (PES) compared with bare metal stents (BMS) in patients undergoing primary angioplasty...
  45. ncbi Prevention of distal embolization in patients undergoing mechanical revascularization for acute myocardial infarction. A review of current status
    Giuseppe De Luca
    Division of Cardiology, Federico II University, Naples, Italy
    Thromb Haemost 96:700-10. 2006
    ....
  46. ncbi Adjunctive mechanical devices to prevent distal embolization in patients undergoing mechanical revascularization for acute myocardial infarction: a meta-analysis of randomized trials
    Giuseppe De Luca
    Division of Cardiology, Ospedale Maggiore della Carita, Universite del Piemonte Orientale, Novara, Italy
    Am Heart J 153:343-53. 2007
    ..The aim of this meta-analysis was to combine data from all randomized trials conducted with adjunctive mechanical devices to prevent distal embolization in AMI...
  47. ncbi Benefits of drug-eluting stents as compared to bare metal stent in ST-segment elevation myocardial infarction: four year results of the PaclitAxel or Sirolimus-Eluting stent vs bare metal stent in primary angiOplasty (PASEO) randomized trial
    Emilio Di Lorenzo
    Division of Cardiology, S G Moscati, Avellino, Italy
    Am Heart J 158:e43-50. 2009
    ..The aim of the current study was to evaluate the short- and long-term benefits of sirolimus-eluting stent (SES) and paclitaxel-eluting stent (PES) as compared to bare-metal stent (BMS) in patients undergoing primary angioplasty...
  48. ncbi Routine stenting vs. balloon angioplasty in ST-segment elevation myocardial infarction due to proximal left anterior descending coronary artery occlusion
    Giuseppe De Luca
    Division of Cardiology and Centro di Biotecnologie per la Ricerca Medica Applicata BRMA, Eastern Piedmont University, Novara, Italy
    J Cardiovasc Med (Hagerstown) 10:22-6. 2009
    ..The aim of this substudy was to investigate the benefits of coronary stenting as compared to balloon angioplasty in patients with proximal left anterior descending artery occlusion...
  49. ncbi Cardiogenic shock developing in the coronary care unit in patients with ST-elevation myocardial infarction
    Giuseppe De Luca
    Division of Cardiology, Maggiore della Carita Hospital, Eastern Piedmont University A Avogadro, and Centro di Biotecnologie per la Ricerca Medica Applicata BRMA, Novara, Italy
    J Cardiovasc Med (Hagerstown) 9:1023-9. 2008
    ..The aim of the current study was to identify, among patients in the BLITZ-1, the clinical predictors, and describe the outcome of patients who developed cardiogenic shock during hospitalization...
  50. ncbi Impact of vessel size on distal embolization, myocardial perfusion and clinical outcome in patients undergoing primary angioplasty for ST-segment elevation myocardial infarction
    Giuseppe De Luca
    Division of Cardiology, and Centro di Biotecnologie per la Ricerca Medica Applicata BRMA, Eastern Piedmont University, Novara, Italy
    J Thromb Thrombolysis 27:198-203. 2009
    ..The aim of the current study was to evaluate the relationship between vessel size, distal embolization, myocardial perfusion and clinical outcome in patients with STEMI treated by primary angioplasty...
  51. ncbi Rheolytic thrombectomy during percutaneous coronary intervention improves long-term outcome in high-risk patients with acute myocardial infarction
    Salvatore De Rosa
    Division of Cardiology, University of Naples Federico II, Naples, Italy
    J Interv Cardiol 20:292-8. 2007
    ....
  52. ncbi Safety of immediate reversal of anticoagulation by protamine to reduce bleeding complications after infarct artery stenting for acute myocardial infarction and adjunctive abciximab therapy
    Guido Parodi
    Division of Cardiology, Careggi Hospital, Florence, Italy
    J Thromb Thrombolysis 30:446-51. 2010
    ....
  53. ncbi Efficacy and safety of drug-eluting stents in ST-segment elevation myocardial infarction: a meta-analysis of randomized trials
    Giuseppe De Luca
    Division of Cardiology, Ospedale Maggiore della Carita, Eastern Piedmont University, Novara, Italy
    Int J Cardiol 133:213-22. 2009
    ..Thus, the aim of the current study was to perform a meta-analysis to evaluate the benefits and safety of DES as compared to BMS in patients undergoing primary angioplasty for STEMI...
  54. ncbi Meta-analysis comparing efficacy and safety of first generation drug-eluting stents to bare-metal stents in patients with diabetes mellitus undergoing primary percutaneous coronary intervention
    Giuseppe De Luca
    Division of Cardiology, Ospedale Maggiore della Carita, Eastern Piedmont University, Novara, Italy Centro di Biotecnologie per la Ricerca Medica Applicata, Eastern Piedmont University, Novara, Italy Electronic address
    Am J Cardiol 111:1295-304. 2013
    ....
  55. ncbi Relation of gender to infarct size in patients with ST-segment elevation myocardial infarction undergoing primary angioplasty
    Giuseppe De Luca
    Division of Cardiology, Maggiore della Carita Hospital, Eastern Piedmont University, Novara, Italy
    Am J Cardiol 111:936-40. 2013
    ....
  56. ncbi Homocysteine and its effects on in-stent restenosis
    Giuseppe De Luca
    Division of Cardiology, Federico II University, Naples, Italy
    Circulation 112:e307-11. 2005
  57. ncbi Comparison between stenting and balloon in elderly patients undergoing primary angioplasty for ST-segment elevation myocardial infarction
    Giuseppe De Luca
    Divison of Cadiology, Ospedale Maggiore della Carita, Universita del Piemonte Orientale A Avogadro, Novara, Italy
    Int J Cardiol 119:306-9. 2007
    ..However, few data have been reported so far in the elderly. Thus, the aim of the current study was to evaluate the benefits from routine stenting in this high-risk subset of patients...
  58. ncbi Role of beta2 adrenergic receptors in human atherosclerotic coronary arteries
    Emanuele Barbato
    Division of Cardiology, Federico II University of Naples, Italy
    Circulation 111:288-94. 2005
    ..This study aimed at assessing the role of beta2-ARs in normal, mildly atherosclerotic, and stenotic human coronary arteries...
  59. ncbi PlA1/PlA2 polymorphism does not influence response to Gp IIb-IIIa inhibitors in patients undergoing coronary angioplasty
    Monica Verdoia
    aDivision of Cardiology bClinical Chemistry, Azienda Ospedaliera Universitaria Maggiore Della Carità, Eastern Piedmont University, Novara, Italy cDepartment of Cardiology, UMC St Radboud, Nijmegen, The Netherlands
    Blood Coagul Fibrinolysis 24:411-8. 2013
    ..This study showed that Leu33Pro polymorphism of Gp IIIa does not affect the extent of inhibition of platelet aggregation by Gp IIb-IIIa inhibitors...
  60. ncbi Mean platelet volume and the risk of periprocedural myocardial infarction in patients undergoing coronary angioplasty
    Monica Verdoia
    Division of Cardiology, Azienda Ospedaliera Universitaria Maggiore Della Carità, C so Mazzini, 18, Eastern Piedmont University, Novara 28100, Italy
    Atherosclerosis 228:136-41. 2013
    ..Therefore, aim of the current study was to evaluate whether MPV is associated with increased risk of PMI after PCI...
  61. ncbi Left atrial asynchrony is a major predictor of 1-year recurrence of atrial fibrillation after electrical cardioversion
    Elisa Rondano
    Cardiology Clinic and General Pathology, Eastern Piedmont University, Azienda Ospedaliera Universitaria Maggiore Della Carità, Novara, Italy
    J Cardiovasc Med (Hagerstown) 11:499-506. 2010
    ..The level of atrial mechanical asynchrony may vary within the atrial fibrillation population and this may have pathophysiological relevance...
  62. ncbi Clinical impact of simultaneous complete revascularization vs. culprit only primary angioplasty in patients with st-elevation myocardial infarction and multivessel disease: a meta-analysis
    Eliano Pio Navarese
    Division of Cardiology, Ospedale Maggiore della Carita, Eastern Piedmont University, Novara, Italy
    J Thromb Thrombolysis 31:217-25. 2011
    ..94 [0.43-2.06], P = 0.88). This meta-analysis showed safety and efficacy of MV PCI approach as compared with COR, with a significant reduction in rate of revascularizations, but no advantages in death and re-MI...
  63. ncbi Silent double aortic arch coincidentally found during cardiac catheterization in elderly man
    Gioel G Secco
    Department of Cardiology, Ospedale Maggiore della Carita, Eastern Piedmont University, Novara, Italy
    Congenit Heart Dis 6:74-6. 2011
    ..During the third angiography, the double aortic arch was coincidentally visualized by using a left Amplatz catheter. The diagnosis was confirmed by 64-slice computed tomography scan...
  64. ncbi Relationship between contractile reserve, Tl-201 uptake, and collateral angiographic circulation in collateral-dependent myocardium: implications regarding the evaluation of myocardial viability
    Federico Piscione
    Division of Cardiology, Federico II University, Naples, Italy
    J Nucl Cardiol 10:17-27. 2003
    ....
  65. ncbi Outcome in patients treated with primary angioplasty for acute myocardial infarction due to left main coronary artery occlusion
    Giuseppe De Luca
    Division of Cardiology, Federico II University, Naples, Italy
    Am J Cardiol 91:235-8. 2003
  66. ncbi Stable ventricular fibrillation in a heterotopic heart transplant recipient
    Gioel Gabrio Secco
    Department of Cardiology, Maggiore della Carita Hospital, University of Eastern Piedmont, Novara, Italy
    Heart Lung Circ 21:747-9. 2012
    ..A coronary angiography and a cardiac MRI confirmed the diagnosis. Six months follow-up ECG was unchanged suggesting the persistence of a double heart rhythm in the same body...
  67. ncbi Cytokines release inhibition from activated monocytes, and reduction of in-stent neointimal growth in humans
    Gabriele Pesarini
    Department of Biomedical Sciences and Surgery, University of Verona, Division of Cardiology, and Laboratory of Clinical Biochemistry and Haematology of the Ospedale Civile Maggiore, Verona, Italy
    Atherosclerosis 211:242-8. 2010
    ..In a sub-group of patients activated NF-kappaB was also evaluated...
  68. ncbi Ischaemic and bleeding complications with new, compared to standard, ADP-antagonist regimens in acute coronary syndromes: a meta-analysis of randomized trials
    E P Navarese
    Maggiore della Carita Hospital, Universita del Piemonte Orientale, Novara, Italy
    QJM 104:561-9. 2011
    ..We aimed to perform a meta-analysis of randomized trials to evaluate the benefits of new oral antiplatelet regimens to block platelet ADP-receptors compared to standard-dose clopidogrel (300 mg loading dose followed by 75 mg/daily)...
  69. ncbi The Zwolle global experience on primary percutaneous coronary intervention
    Giuseppe De Luca
    Department of Cardiology, Isala Klinieken, De Weezenlanden Hospital, Zwolle, The Netherlands
    Ital Heart J 6:453-8. 2005
    ..Finally, the use of the Zwolle risk score may help to identify low-risk patients who could be safely discharged within 36-48 hours after primary angioplasty, with a significant reduction in the costs of hospitalization...
  70. ncbi Time-to-treatment significantly affects the extent of ST-segment resolution and myocardial blush in patients with acute myocardial infarction treated by primary angioplasty
    Giuseppe De Luca
    Department of Cardiology, Isala Klinieken, Hospital De Weezenlanden, Groot Wezenland, 20, Zwolle 8011 JW, The Netherlands
    Eur Heart J 25:1009-13. 2004
    ..The aim of our study was to evaluate the relationship between time-to-treatment and myocardial perfusion in patients with ST-segment-elevation myocardial infarction (STEMI) treated by primary angioplasty...
  71. ncbi Prognostic significance of residual cumulative ST-segment deviation after mechanical reperfusion in patients with ST-segment elevation myocardial infarction
    Giuseppe De Luca
    Department of Cardiology, Isala Klinieken, Hospital De Weezenlanden, Zwolle, The Netherlands
    Am Heart J 150:1248-54. 2005
    ....
  72. ncbi Comparison between ticlopidine and clopidogrel in patients with ST-segment elevation myocardial infarction treated with coronary stenting
    Giuseppe De Luca
    Department of Cardiology, Isala Klinieken, Hospital De Weezenlanden, Zwolle, The Netherlands
    Thromb Haemost 91:1084-9. 2004
    ..This study shows no difference in long-term clinical outcome between clopidogrel and ticlopidine as adjunctive antiplatelet therapy in patients with STEMI undergoing stent implantation...
  73. ncbi Prognostic assessment of patients with acute myocardial infarction treated with primary angioplasty: implications for early discharge
    Giuseppe De Luca
    Department of Cardiology, Isala Klinieken, Hospital De Weezenlanden, Zwolle, The Netherlands
    Circulation 109:2737-43. 2004
    ..It reliably identifies a large group of patients at very low risk, who may safely be discharged early after primary angioplasty...
  74. ncbi Impact of ST-segment depression resolution on mortality after successful mechanical reperfusion in patients with ST-segment elevation acute myocardial infarction
    Giuseppe De Luca
    Department of Cardiology, ISALA Klinieken De Weezenlanden Hospital, Groot Wezeland 20, 8011 JW Zwolle, The Netherlands
    Am J Cardiol 95:234-6. 2005
    ..0004). At multivariate analysis, incomplete resolution of ST-segment depression was an independent predictor of 1-year mortality (p = 0.028)...
  75. ncbi Preprocedural TIMI flow and mortality in patients with acute myocardial infarction treated by primary angioplasty
    Giuseppe De Luca
    Isala Klinieken, Hospital De Weezenlanden, Zwolle, The Netherlands
    J Am Coll Cardiol 43:1363-7. 2004
    ....
  76. ncbi Time delay to treatment and mortality in primary angioplasty for acute myocardial infarction: every minute of delay counts
    Giuseppe De Luca
    Department of Cardiology, Isala Klinieken, Zwolle, The Netherlands
    Circulation 109:1223-5. 2004
    ..Therefore, all efforts should be made to shorten the total ischemic time, not only for thrombolytic therapy but also for primary angioplasty...
  77. ncbi Impact of routine stenting on clinical outcome in diabetic patients undergoing primary angioplasty for ST-segment elevation myocardial infarction
    Giuseppe De Luca
    Department of Cardiology, Isala Klinieken Hospital De Weezenlanden, Groot Wezenland 20, 8011 JW Zwolle, Netherlands
    Diabetes Care 29:920-3. 2006
  78. ncbi Coronary revascularization for non-ST elevation acute coronary syndrome: state of the art
    Arno Breeman
    Isala Klinieken, Zwolle and University Hospital Rotterdam, Erasmus Medical Centre, Rotterdam, The Netherlands
    J Cardiovasc Med (Hagerstown) 7:108-13. 2006
    ..1 mV, accelerated angina in the prior 2 months, nitrate use in the prior week before admission and elevated troponin...
  79. ncbi Relationship between patient's risk profile and benefits in mortality from adjunctive abciximab to mechanical revascularization for ST-segment elevation myocardial infarction: a meta-regression analysis of randomized trials
    Giuseppe De Luca
    J Am Coll Cardiol 47:685-6. 2006
  80. ncbi Predictors and clinical implications of early reinfarction after primary angioplasty for ST-segment elevation myocardial infarction
    Giuseppe De Luca
    Department of Cardiology, Isala Klinieken, Hospital De Weezenlanden, Zwolle, The Netherlands
    Am Heart J 151:1256-9. 2006
    ..Early reinfarction is an independent predictor of 1-year mortality...
  81. ncbi Impact of routine stenting on myocardial perfusion and the extent of myocardial necrosis in patients undergoing primary angioplasty for ST-segment elevation myocardial infarction
    Giuseppe De Luca
    Department of Cardiology, Isala Klinieken, Hospital De Weezenlanden, Zwolle, The Netherlands
    Am Heart J 151:1296.e1-6. 2006
    ..CONCLUSIONS: As compared with balloon angioplasty, routine stenting does not improve myocardial perfusion, the rate of distal embolization, and the extent of myocardial necrosis in a large cohort of unselected patients with STEMI...
  82. ncbi Impact of statin therapy at discharge on 1-year mortality in patients with ST-segment elevation myocardial infarction treated with primary angioplasty
    Giuseppe De Luca
    Division of Cardiology, Isala Klinieken, Hospital De Weezenlanden, Groot Wezeland 20, 8011 JW Zwolle, The Netherlands
    Atherosclerosis 189:186-92. 2006
    ..12-0.47], p<0.0001). CONCLUSIONS: Statin therapy at discharge was associated with a significant reduction in 1-year mortality after primary angioplasty for STEMI. Therefore, the use of statins is highly recommended in these patients...
  83. ncbi Comparison between stenting and balloon angioplasty in patients undergoing primary angioplasty of small coronary vessels
    Giuseppe De Luca
    Department of Cardiology, Isala Klinieken, Hospital De Weezenlanden, Zwolle, The Netherlands
    Am Heart J 152:915-20. 2006
    ..Future trials are certainly needed to evaluate the safety and benefits of drug-eluting stents in this high-risk subset of patients...
  84. ncbi Patency of infarct related artery after pharmacological reperfusion during transfer to primary percutaneous coronary intervention influences left ventricular function and one-year clinical outcome
    Dariusz Dudek
    2nd Department of Cardiology, Institute of Cardiology, Jagiellonian University Medical College, Krakow, Poland
    Int J Cardiol 124:326-31. 2008
    ....
  85. ncbi Folate therapy and in-stent restenosis after coronary stenting
    Helmut Lange
    Kardiologische Praxis, Klinikum Links der Weser, Heart Center, Bremen, Germany
    N Engl J Med 350:2673-81. 2004
    ..CONCLUSIONS: Contrary to previous findings, the administration of folate, vitamin B6, and vitamin B12 after coronary stenting may increase the risk of in-stent restenosis and the need for target-vessel revascularization...
  86. ncbi Sex-related differences in outcome after ST-segment elevation myocardial infarction treated by primary angioplasty: data from the Zwolle Myocardial Infarction study
    Giuseppe De Luca
    Department of Cardiology, Isala Klinieken, Hospital De Weezenlanden, Zwolle, The Netherlands
    Am Heart J 148:852-6. 2004
    ..Female sex did not emerge as an independent predictor of death...
  87. ncbi Preprocedural Thrombolysis in Myocardial Infarction (TIMI) flow significantly affects the extent of ST-segment resolution and myocardial blush in patients with acute anterior myocardial infarction treated by primary angioplasty
    Giuseppe De Luca
    Isala Klinieken, Hospital De Weezenlanden, Zwolle, The Netherlands
    Am Heart J 150:827-31. 2005
    ..Further studies are needed to investigate the impact of early adjunctive pharmacological therapy on preprocedural TIMI flow and mortality in these high-risk patients...
  88. ncbi Ageing, impaired myocardial perfusion, and mortality in patients with ST-segment elevation myocardial infarction treated by primary angioplasty
    Giuseppe De Luca
    Department of Cardiology, Isala Klinieken, Hospital De Weezenlanden, Groot Weezelanden 20, 8011 JW Zwolle, The Netherlands
    Eur Heart J 26:662-6. 2005
    ..CONCLUSION: This study shows that impaired reperfusion is an additional determinant of the poor outcome observed with advanced age in patients with STEMI undergoing mechanical revascularization...
  89. ncbi Unsuccessful reperfusion in patients with ST-segment elevation myocardial infarction treated by primary angioplasty
    Giuseppe De Luca
    Department of Cardiology, ISALA Klinieken De Weezenlanden Hospital, 8011 JW Zwolle, The Netherlands
    Am Heart J 150:557-62. 2005
    ..Future research should be focused on these high-risk patients, and treatment strategies should be developed to improve myocardial perfusion and clinical outcome...
  90. ncbi Stenting and abciximab in primary angioplasty: a review of current status
    Giuseppe De Luca
    Division of Cardiology, Isala Klinieken, De Weezenlanden Hospital, Zwolle, The Netherlands
    Ital Heart J 6:874-80. 2005
    ..Further large randomized trials are needed to clarify the potential role of small molecules in primary angioplasty for STEMI...
  91. ncbi Impact of adjunctive tirofiban administration on myocardial perfusion and mortality in patients undergoing primary angioplasty for ST-segment elevation myocardial infarction
    Giuseppe De Luca
    Department of Cardiology, Isala Klinieken, Zwolle, The Netherlands
    Thromb Haemost 93:820-3. 2005
    ..This study shows that, when compared to control group, adjunctive tirofiban before primary angioplasty for STEMI is associated with better myocardial perfusion and a reduction in 1-year mortality...
  92. ncbi Circadian variation in myocardial perfusion and mortality in patients with ST-segment elevation myocardial infarction treated by primary angioplasty
    Giuseppe De Luca
    Department of Cardiology, Isala Klinieken, Hospital De Weezenlanden, Zwolle, The Netherlands
    Am Heart J 150:1185-9. 2005
    ..13-3.26, P = .016). CONCLUSIONS: This is the first study showing a significant relationship between the time of treatment, myocardial perfusion, and long-term mortality in patients with STEMI undergoing mechanical reperfusion...
  93. ncbi ST-segment elevation resolution and outcome in patients treated with primary angioplasty and glucose-insulin-potassium infusion
    Iwan C C van der Horst
    Department of Cardiology, Thoraxcenter, University Medical Center Groningen, Groningen, The Netherlands
    Am Heart J 149:1135. 2005
    ..To evaluate the impact of adjunctive high-dose glucose-insulin-potassium (GIK) on ST-segment elevation resolution in patients with ST-segment elevation myocardial infarction (MI)...
  94. ncbi Abciximab as adjunctive therapy to reperfusion in acute ST-segment elevation myocardial infarction: a meta-analysis of randomized trials
    Giuseppe De Luca
    Isala Klinieken, Hospital De Weezenlanden, Zwolle, The Netherlands
    JAMA 293:1759-65. 2005
    ..The 30-day reinfarction rate is significantly reduced in patients treated with either fibrinolysis or primary angioplasty. A higher risk of major bleeding complications is observed with abciximab in association with fibrinolysis...
  95. ncbi In-stent thrombosis after discontinuation of antiplatelet therapy 2 years after DES implantation: a case report
    Giuseppe De Luca
    Int J Cardiol 116:399-400. 2007
  96. ncbi Absence of seasonal variation in myocardial perfusion, enzymatic infarct size, and mortality in patients with ST-segment elevation myocardial infarction treated with primary angioplasty
    Giuseppe De Luca
    Department of Cardiology, Isala Klinieken, Hospital De Weezenlanden, Zwolle, The Netherlands
    Am J Cardiol 95:1459-61. 2005
    ..No difference was observed in the prevalence of heart failure at presentation and in myocardial perfusion, enzymatic infarct size, and 1-year mortality...
  97. ncbi Prognostic value of tissue Doppler-derived ventricular asynchrony in patients with left bundle branch block but not advanced heart failure
    Rodolfo Citro
    U O UTIC Cardiologia, San Luca Hospital, Vallo della Lucania, Salerno, Italy
    J Cardiovasc Med (Hagerstown) 8:568-74. 2007
    ..The aim of the present study was to evaluate the prognostic significance of tissue Doppler echocardiography (TDE)-derived ventricular asynchrony in patients with left bundle branch block (LBBB) but not advanced heart failure...
  98. ncbi Relation of interhospital delay and mortality in patients with ST-segment elevation myocardial infarction transferred for primary coronary angioplasty
    Giuseppe De Luca
    Department of Cardiology, Isala Klinieken, Hospital De Weezenlanden, Zwolle, The Netherlands
    Am J Cardiol 95:1361-3. 2005
    ..5, 95% confidence interval 1.07 to 2.12; p = 0.019). These results suggest that in patients with ST-segment elevation myocardial infarction transferred for primary angioplasty, all efforts should be made to reduce time to treatment...
  99. ncbi Symptom-onset-to-balloon time and mortality in patients with acute myocardial infarction treated by primary angioplasty
    Giuseppe De Luca
    Department of Cardiology, Isala Klinieken, Hospital De Weezenlanden, Zwolle, The Netherlands
    J Am Coll Cardiol 42:991-7. 2003
    ..Furthermore, a symptom-onset-to-balloon time >4 h was identified as independent predictor of one-year mortality...
  100. ncbi Impact of beta-blocker therapy at discharge on long-term mortality after primary angioplasty for ST-segment elevation myocardial infarction
    Giuseppe De Luca
    The Division of Cardiology, Isala Klinieken, Hospital De Weezenlanden, Zwolle, The Netherlands
    Am J Cardiol 96:806-9. 2005
    ..07, p = NS). Benefits in terms of mortality rate that were conferred by beta blockers were confirmed at multivariate analysis that was restricted to patients who had anterior wall infarction (RR 0.43, 95% CI 0.21 to 0.86, p = 0.022)...
  101. ncbi Prediction of long-term effects of revascularization on regional and global left ventricular function by dobutamine echocardiography and rest Tl-201 imaging alone and in combination in patients with chronic coronary artery disease
    Santo Dellegrottaglie
    Department of Clinical Medicine, Cardiovascular and Immunological Sciences, Naples, Italy
    J Nucl Cardiol 9:174-82. 2002
    ..CONCLUSIONS: The combination of Tl-201 SPECT and DE data provides higher accuracy than either technique alone for prediction of recovery of regional and global function after revascularization...