Elvira De Leonibus

Summary

Affiliation: University of Rome La Sapienza
Country: Italy

Publications

  1. ncbi request reprint Spatial deficits in a mouse model of Parkinson disease
    Elvira De Leonibus
    Dipartimento di Genetica e Biologia Molecolare C Darwin, Universita degli Studi di Roma La Sapienza, Piazzale Aldo Moro, 5, Rome, Italy
    Psychopharmacology (Berl) 194:517-25. 2007
  2. ncbi request reprint Distinct kinds of novelty processing differentially increase extracellular dopamine in different brain regions
    Elvira De Leonibus
    Department of Psychoneuropharmacology, Nijmegen Institute of Neurosciences, University of Nijmegen, The Netherlands
    Eur J Neurosci 23:1332-40. 2006
  3. pmc A study on the role of the dorsal striatum and the nucleus accumbens in allocentric and egocentric spatial memory consolidation
    Elvira De Leonibus
    Dipartimento di Genetica e Biologia Molecolare, Universita di Roma La Sapienza, 00185 Rome, Italy
    Learn Mem 12:491-503. 2005
  4. doi request reprint Interaction between the mGlu receptors 5 antagonist, MPEP, and amphetamine on memory and motor functions in mice
    Francesca Managò
    Dipartimento di Biologia e Biotecnologie C Darwin, Universita degli Studi di Roma La Sapienza, Rome, Italy
    Psychopharmacology (Berl) 226:541-50. 2013
  5. ncbi request reprint Co-activation of glutamate and dopamine receptors within the nucleus accumbens is required for spatial memory consolidation in mice
    Valentina Ferretti
    Dipartimento di Genetica e Biologia Molecolare, Universita di Roma La Sapienza, 00185 Rome, Italy
    Psychopharmacology (Berl) 179:108-16. 2005
  6. doi request reprint Metabotropic glutamate receptors 5 blockade reverses spatial memory deficits in a mouse model of Parkinson's disease
    Elvira De Leonibus
    Dipartimento di Genetica e Biologia Molecolare C Darwin, Universita degli Studi di Roma La Sapienza, Rome, Italy
    Neuropsychopharmacology 34:729-38. 2009
  7. ncbi request reprint Distinct roles of the different ionotropic glutamate receptors within the nucleus accumbens in passive-avoidance learning and memory in mice
    Elvira De Leonibus
    Dipartimento di Genetica e Biologia Molecolare, Universita di Roma La Sapienza, P le Aldo Moro 5, 00185, Rome, Italy
    Eur J Neurosci 18:2365-73. 2003
  8. doi request reprint Role of dopamine receptors subtypes, D1-like and D2-like, within the nucleus accumbens subregions, core and shell, on memory consolidation in the one-trial inhibitory avoidance task
    Francesca Managò
    Dipartimento di Genetica e Biologia Molecolare C Darwin, Universita degli Studi di Roma La Sapienza, Rome 00185, Italy
    Learn Mem 16:46-52. 2009
  9. doi request reprint Cognitive and neural determinants of response strategy in the dual-solution plus-maze task
    Elvira De Leonibus
    Dipartimento di Biologia e Biotecnologie, Universita degli Studi di Roma La Sapienza, 00185 Rome, Italy
    Learn Mem 18:241-4. 2011
  10. ncbi request reprint Pharmacological evidence of the role of dorsal striatum in spatial memory consolidation in mice
    Elvira De Leonibus
    Dipartimento di Genetica e Biologia Molecolare, Universita degli Studi di Roma La Sapienza, Italy
    Behav Neurosci 117:685-94. 2003

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Spatial deficits in a mouse model of Parkinson disease
    Elvira De Leonibus
    Dipartimento di Genetica e Biologia Molecolare C Darwin, Universita degli Studi di Roma La Sapienza, Piazzale Aldo Moro, 5, Rome, Italy
    Psychopharmacology (Berl) 194:517-25. 2007
    ..However, more recent evidence suggests that dopamine loss in the striatum is responsible for the visuo-spatial abnormalities in PD. Studies based on animal models of PD did not specifically address this question...
  2. ncbi request reprint Distinct kinds of novelty processing differentially increase extracellular dopamine in different brain regions
    Elvira De Leonibus
    Department of Psychoneuropharmacology, Nijmegen Institute of Neurosciences, University of Nijmegen, The Netherlands
    Eur J Neurosci 23:1332-40. 2006
    ..None of the stimuli presented affected DA in the accumbal core. This study provided the original evidence that DA in the various terminal regions is differentially coupled to distinct aspects of novelty processing...
  3. pmc A study on the role of the dorsal striatum and the nucleus accumbens in allocentric and egocentric spatial memory consolidation
    Elvira De Leonibus
    Dipartimento di Genetica e Biologia Molecolare, Universita di Roma La Sapienza, 00185 Rome, Italy
    Learn Mem 12:491-503. 2005
    ..Intra-accumbens AP-5 administration, instead, impaired animals trained using both procedures...
  4. doi request reprint Interaction between the mGlu receptors 5 antagonist, MPEP, and amphetamine on memory and motor functions in mice
    Francesca Managò
    Dipartimento di Biologia e Biotecnologie C Darwin, Universita degli Studi di Roma La Sapienza, Rome, Italy
    Psychopharmacology (Berl) 226:541-50. 2013
    ..Metabotropic glutamate mGlu receptors 5 (mGluR5) receptors are abundant in corticolimbic circuitry where they modulate glutamate and dopamine signal transduction...
  5. ncbi request reprint Co-activation of glutamate and dopamine receptors within the nucleus accumbens is required for spatial memory consolidation in mice
    Valentina Ferretti
    Dipartimento di Genetica e Biologia Molecolare, Universita di Roma La Sapienza, 00185 Rome, Italy
    Psychopharmacology (Berl) 179:108-16. 2005
    ....
  6. doi request reprint Metabotropic glutamate receptors 5 blockade reverses spatial memory deficits in a mouse model of Parkinson's disease
    Elvira De Leonibus
    Dipartimento di Genetica e Biologia Molecolare C Darwin, Universita degli Studi di Roma La Sapienza, Rome, Italy
    Neuropsychopharmacology 34:729-38. 2009
    ..Further, they demonstrate that mGluR5 blockade may also have beneficial effects on cognitive deficits induced by dopamine depletion...
  7. ncbi request reprint Distinct roles of the different ionotropic glutamate receptors within the nucleus accumbens in passive-avoidance learning and memory in mice
    Elvira De Leonibus
    Dipartimento di Genetica e Biologia Molecolare, Universita di Roma La Sapienza, P le Aldo Moro 5, 00185, Rome, Italy
    Eur J Neurosci 18:2365-73. 2003
    ..AMPA receptors, instead, are necessary for the acquisition and the expression but not consolidation of inhibitory avoidance memory...
  8. doi request reprint Role of dopamine receptors subtypes, D1-like and D2-like, within the nucleus accumbens subregions, core and shell, on memory consolidation in the one-trial inhibitory avoidance task
    Francesca Managò
    Dipartimento di Genetica e Biologia Molecolare C Darwin, Universita degli Studi di Roma La Sapienza, Rome 00185, Italy
    Learn Mem 16:46-52. 2009
    ....
  9. doi request reprint Cognitive and neural determinants of response strategy in the dual-solution plus-maze task
    Elvira De Leonibus
    Dipartimento di Biologia e Biotecnologie, Universita degli Studi di Roma La Sapienza, 00185 Rome, Italy
    Learn Mem 18:241-4. 2011
    ..These findings have relevant implications for the understanding of the learning mechanisms underlying different overt behaviors in this widely used maze task...
  10. ncbi request reprint Pharmacological evidence of the role of dorsal striatum in spatial memory consolidation in mice
    Elvira De Leonibus
    Dipartimento di Genetica e Biologia Molecolare, Universita degli Studi di Roma La Sapienza, Italy
    Behav Neurosci 117:685-94. 2003
    ..The results are discussed with reference to a possible selective involvement of this structure in processing spatial information acquired through an egocentric, but not an allocentric, frame of reference...
  11. pmc IPLEX administration improves motor neuron survival and ameliorates motor functions in a severe mouse model of spinal muscular atrophy
    Michela Murdocca
    Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy
    Mol Med 18:1076-85. 2012
    ..Collectively, our data indicate IPLEX as a good therapeutic candidate to hinder the progression of the neurodegenerative process in SMA...
  12. ncbi request reprint Targeting group III metabotropic glutamate receptors produces complex behavioral effects in rodent models of Parkinson's disease
    Sebastien Lopez
    Laboratoire de Neurobiologie de la Cognition, Aix Marseille Universite, Centre National de la Recherche Scientifique Unité Mixte de Recherche 6155, 13331 Marseille, France
    J Neurosci 27:6701-11. 2007
    ..The opposite effects produced by group III mGluR activation in the SNr, also observed with a selective mGluR8 agonist, support the use of subtype-selective group III mGluR agonists as a potential antiparkinsonian strategy...