Research Topics
Species | Elvira De LeonibusSummaryAffiliation: University of Rome La Sapienza Country: Italy Publications
| Collaborators
|
Detail Information
Publications
A study on the role of the dorsal striatum and the nucleus accumbens in allocentric and egocentric spatial memory consolidationElvira De Leonibus
Dipartimento di Genetica e Biologia Molecolare, Universita di Roma La Sapienza, 00185 Rome, Italy
Learn Mem 12:491-503. 2005..Intra-accumbens AP-5 administration, instead, impaired animals trained using both procedures...
Distinct kinds of novelty processing differentially increase extracellular dopamine in different brain regionsElvira De Leonibus
Department of Psychoneuropharmacology, Nijmegen Institute of Neurosciences, University of Nijmegen, The Netherlands
Eur J Neurosci 23:1332-40. 2006..None of the stimuli presented affected DA in the accumbal core. This study provided the original evidence that DA in the various terminal regions is differentially coupled to distinct aspects of novelty processing...- Spatial deficits in a mouse model of Parkinson diseaseElvira De Leonibus
Dipartimento di Genetica e Biologia Molecolare C Darwin, Universita degli Studi di Roma La Sapienza, Piazzale Aldo Moro, 5, Rome, Italy
Psychopharmacology (Berl) 194:517-25. 2007..However, more recent evidence suggests that dopamine loss in the striatum is responsible for the visuo-spatial abnormalities in PD. Studies based on animal models of PD did not specifically address this question... - Co-activation of glutamate and dopamine receptors within the nucleus accumbens is required for spatial memory consolidation in miceValentina Ferretti
Dipartimento di Genetica e Biologia Molecolare, , 00185 Rome, Italy
Psychopharmacology (Berl) 179:108-16. 2005..CONCLUSIONS: These results demonstrate that glutamate-dopamine receptor interactions within the accumbens are essential for the consolidation process of spatial information... 
Metabotropic glutamate receptors 5 blockade reverses spatial memory deficits in a mouse model of Parkinson's diseaseElvira De Leonibus
Dipartimento di Genetica e Biologia Molecolare C Darwin, Universita degli Studi di Roma La Sapienza, Rome, Italy
Neuropsychopharmacology 34:729-38. 2009..Further, they demonstrate that mGluR5 blockade may also have beneficial effects on cognitive deficits induced by dopamine depletion...- Distinct roles of the different ionotropic glutamate receptors within the nucleus accumbens in passive-avoidance learning and memory in miceElvira De Leonibus
Dipartimento di Genetica e Biologia Molecolare, , P .le Aldo Moro 5, 00185, Rome, Italy
Eur J Neurosci 18:2365-73. 2003..AMPA receptors, instead, are necessary for the acquisition and the expression but not consolidation of inhibitory avoidance memory... - Role of dopamine receptors subtypes, D1-like and D2-like, within the nucleus accumbens subregions, core and shell, on memory consolidation in the one-trial inhibitory avoidance taskFrancesca Managò
Dipartimento di Genetica e Biologia Molecolare C Darwin, Universita degli Studi di Roma La Sapienza, Rome 00185, Italy
Learn Mem 16:46-52. 2009.... - Cognitive and neural determinants of response strategy in the dual-solution plus-maze taskElvira De Leonibus
Dipartimento di Biologia e Biotecnologie, Universita degli Studi di Roma La Sapienza, 00185 Rome, Italy
Learn Mem 18:241-4. 2011..These findings have relevant implications for the understanding of the learning mechanisms underlying different overt behaviors in this widely used maze task... - Pharmacological evidence of the role of dorsal striatum in spatial memory consolidation in miceElvira De Leonibus
Dipartimento di Genetica e Biologia Molecolare, , Italy
Behav Neurosci 117:685-94. 2003..The results are discussed with reference to a possible selective involvement of this structure in processing spatial information acquired through an egocentric, but not an allocentric, frame of reference... - Targeting group III metabotropic glutamate receptors produces complex behavioral effects in rodent models of Parkinson's diseaseSebastien Lopez
Laboratoire de Neurobiologie de la Cognition, Aix Marseille Universite, Centre National de la Recherche Scientifique Unité Mixte de Recherche 6155, 13331 Marseille, France
J Neurosci 27:6701-11. 2007..The opposite effects produced by group III mGluR activation in the SNr, also observed with a selective mGluR8 agonist, support the use of subtype-selective group III mGluR agonists as a potential antiparkinsonian strategy...