Affiliation: University of Padova
- Beneficial effects of GH/IGF-1 on skeletal muscle atrophy and function in experimental heart failureLuciano Dalla Libera
Internal Medicine II, Ospedale S Bortolo, Viale Rodolfi 37, 36100 Vicenza, Italy
Am J Physiol Cell Physiol 286:C138-44. 2004..These findings may provide an insight into the therapeutic strategy of GH given to patients with CHF to improve exercise capacity...
- Sphingosine 1-phosphate signaling is involved in skeletal muscle regenerationDaniela Danieli-Betto
Dept of Human Anatomy and Physiology, Univ of Padova, Via Marzolo 3, 35131 Padua, Italy
Am J Physiol Cell Physiol 298:C550-8. 2010..The present results show that S1P signaling participates in the regenerative processes of skeletal muscle...
- Sphingosine 1-phosphate protects mouse extensor digitorum longus skeletal muscle during fatigueDaniela Danieli-Betto
Department of Human Anatomy and Physiology, University of Padua, Via Marzolo 3, 35131 Padua, Italy
Am J Physiol Cell Physiol 288:C1367-73. 2005....
- Trophic action of sphingosine 1-phosphate in denervated rat soleus muscleMarika Zanin
Department of Human Anatomy and Physiology, University of Padua, Padua, Italy
Am J Physiol Cell Physiol 294:C36-46. 2008..Denervation produced the down regulation of S1P(1) and S1P(3) receptors, regardless of the presence of the receptor agonist. In conclusion, the results suggest that S1P acts as a trophic factor of skeletal muscle...
- Deficiency of alpha-sarcoglycan differently affects fast- and slow-twitch skeletal musclesDaniela Danieli-Betto
Department of Human Anatomy and Physiology, University of Padova, Italy
Am J Physiol Regul Integr Comp Physiol 289:R1328-37. 2005..In conclusion, this study revealed profound distinctive biochemical and physiological modifications in fast- and slow-twitch muscles resulting from alpha-sarcoglycan deficiency...
- High-frequency fatigue of skeletal muscle: role of extracellular Ca(2+)Elena Germinario
Department of Human Anatomy and Physiology, University of Padova, Via Marzolo 3, 35131 Padova, Italy
Eur J Appl Physiol 104:445-53. 2008..These results indicate that a transmembrane Ca(2+) influx, mainly through NCX, may play a protective role during HFF development in soleus muscle...
- Eccentric contractions lead to myofibrillar dysfunction in muscular dystrophyBert Blaauw
Dept of Human Anatomy and Physiology, Univ of Padua, Padua, Italy
J Appl Physiol 108:105-11. 2010....
- Isoform switching in myofibrillar and excitation-contraction coupling proteins contributes to diminished contractile function in regenerating rat soleus muscleAlessandra Esposito
Department of Human Anatomy and Physiology, University of Padova, Padova, Italy
J Appl Physiol 102:1640-8. 2007..The present results indicate that the expression of developmental proteins determines the incomplete functional recovery of regenerating soleus...
- Skeletal muscle myofibrillar protein oxidation in heart failure and the protective effect of CarvedilolLuciano Dalla Libera
CNR Institute of Neurosciences, Unit for Neuromuscular Biology and Pathophysiology, Department of Biomedical Sciences, University of Padova, Viale G Colombo 3, 35100 Padova, Italy
J Mol Cell Cardiol 38:803-7. 2005..Inhibition of reactive oxygen species (ROS) production, and of pro-inflammatory cytokines may also lead to a decreased muscle wastage, another factor contributing to worsening of exercise tolerance...
- Early changes of type 2B fibers after denervation of rat EDL skeletal muscleElena Germinario
Dipartimento di Anatomia e Fisiologia Umana, Centro di Studio per la Biologia e la Fisiopatologia Muscolare, I-35131 Padova, Italy
J Appl Physiol 92:2045-52. 2002..Our results indicate that type 2B fiber functional properties are highly sensitive to the interruption of nerve supply. Moreover, most of 2-day-denervated changes were reverted at 7 days...
- The T-tubule membrane ATP-operated P2X4 receptor influences contractility of skeletal muscleDorianna Sandonà
Department of Biomedical and Experimental Sciences, University of Padova, Padova, Italy
FASEB J 19:1184-6. 2005..05 Hz) stimulation. These data reveal that ATP-mediated Ca2+ entry, most likely through P2X4 receptor, may play an important role in modulating the contractility of skeletal muscle...
- Denervation in murine fast-twitch muscle: short-term physiological changes and temporal expression profilingAnna Raffaello
Centro di Ricerca Interdipartimentale per le Biotecnologie Innovative Biotechnology Center, University of Padova, Padua, Italy
Physiol Genomics 25:60-74. 2006..We conclude that, if studied at the mRNA level, fast muscles appear not less responsive than slow muscles to the interruption of neural stimulation...