Fulvio Cruciani

Summary

Affiliation: University of Rome La Sapienza
Country: Italy

Publications

  1. pmc A back migration from Asia to sub-Saharan Africa is supported by high-resolution analysis of human Y-chromosome haplotypes
    Fulvio Cruciani
    Dipartimenti di Genetica e Biologia Molecolare, Universita La Sapienza, Rome, Italy
    Am J Hum Genet 70:1197-214. 2002
  2. pmc Molecular dissection of the basal clades in the human Y chromosome phylogenetic tree
    Rosaria Scozzari
    Dipartimento di Biologia e Biotecnologie Charles Darwin, Sapienza Universita di Roma, Rome, Italy
    PLoS ONE 7:e49170. 2012
  3. ncbi request reprint Linkage disequilibrium analysis of the human adenosine deaminase (ada) gene provides evidence for a lack of correlation between hot spots of equal and unequal homologous recombination
    Fulvio Cruciani
    Dipartimento di Genetica e Biologia Molecolare, Universita La Sapienza, P le Aldo Moro 5, 00185 Rome, Italy
    Genomics 82:20-33. 2003
  4. pmc A revised root for the human Y chromosomal phylogenetic tree: the origin of patrilineal diversity in Africa
    Fulvio Cruciani
    Dipartimento di Biologia e Biotecnologie C Darwin, Sapienza Universita di Roma, Rome 00185, Italy
    Am J Hum Genet 88:814-8. 2011
  5. pmc Human Y chromosome haplogroup R-V88: a paternal genetic record of early mid Holocene trans-Saharan connections and the spread of Chadic languages
    Fulvio Cruciani
    Dipartimento di Genetica e Biologia Molecolare, Sapienza Universita di Roma, Rome, Italy
    Eur J Hum Genet 18:800-7. 2010
  6. ncbi request reprint Tracing past human male movements in northern/eastern Africa and western Eurasia: new clues from Y-chromosomal haplogroups E-M78 and J-M12
    Fulvio Cruciani
    Dipartimento di Genetica e Biologia Molecolare, Sapienza Universita di Roma, Rome, Italy, and Laboratoire d Immunologie, Hopital de Sainte Marguerite, Marseille, France
    Mol Biol Evol 24:1300-11. 2007
  7. ncbi request reprint Molecular dissection of the Y chromosome haplogroup E-M78 (E3b1a): a posteriori evaluation of a microsatellite-network-based approach through six new biallelic markers
    Fulvio Cruciani
    Dipartimento di Genetica e Biologia Molecolare, Universita La Sapienza, Rome, Italy
    Hum Mutat 27:831-2. 2006
  8. doi request reprint Genetic diversity patterns at the human clock gene period 2 are suggestive of population-specific positive selection
    Fulvio Cruciani
    Dipartimento di Genetica e Biologia Molecolare, Sapienza Universita di Roma, Rome, Italy
    Eur J Hum Genet 16:1526-34. 2008
  9. ncbi request reprint Recurrent mutation in SNPs within Y chromosome E3b (E-M215) haplogroup: a rebuttal
    Fulvio Cruciani
    Department of Genetics and Molecular Biology, Sapienza Universita di Roma, Rome 00185, Italy
    Am J Hum Biol 20:614-6. 2008
  10. doi request reprint Footprints of X-to-Y gene conversion in recent human evolution
    Beniamino Trombetta
    Dipartimento di Genetica e Biologia Molecolare, Sapienza Universita di Roma, Rome, Italy
    Mol Biol Evol 27:714-25. 2010

Collaborators

Detail Information

Publications23

  1. pmc A back migration from Asia to sub-Saharan Africa is supported by high-resolution analysis of human Y-chromosome haplotypes
    Fulvio Cruciani
    Dipartimenti di Genetica e Biologia Molecolare, Universita La Sapienza, Rome, Italy
    Am J Hum Genet 70:1197-214. 2002
    ..Haplogroup IX Y chromosomes appear to have been involved in such a migration, the traces of which can now be observed mostly in northern Cameroon...
  2. pmc Molecular dissection of the basal clades in the human Y chromosome phylogenetic tree
    Rosaria Scozzari
    Dipartimento di Biologia e Biotecnologie Charles Darwin, Sapienza Universita di Roma, Rome, Italy
    PLoS ONE 7:e49170. 2012
    ..Our data provide a highly resolved branching in the African-specific portion of the Y tree and support the hypothesis of an origin in the north-western quadrant of the African continent for the human MSY diversity...
  3. ncbi request reprint Linkage disequilibrium analysis of the human adenosine deaminase (ada) gene provides evidence for a lack of correlation between hot spots of equal and unequal homologous recombination
    Fulvio Cruciani
    Dipartimento di Genetica e Biologia Molecolare, Universita La Sapienza, P le Aldo Moro 5, 00185 Rome, Italy
    Genomics 82:20-33. 2003
    ..This observation provides the first evidence for an absence of correlation between hot spots of equal and unequal homologous recombination...
  4. pmc A revised root for the human Y chromosomal phylogenetic tree: the origin of patrilineal diversity in Africa
    Fulvio Cruciani
    Dipartimento di Biologia e Biotecnologie C Darwin, Sapienza Universita di Roma, Rome 00185, Italy
    Am J Hum Genet 88:814-8. 2011
    ..An analysis of 2204 African DNA samples showed that the deepest clades of the revised MSY phylogeny are currently found in central and northwest Africa, opening new perspectives on early human presence in the continent...
  5. pmc Human Y chromosome haplogroup R-V88: a paternal genetic record of early mid Holocene trans-Saharan connections and the spread of Chadic languages
    Fulvio Cruciani
    Dipartimento di Genetica e Biologia Molecolare, Sapienza Universita di Roma, Rome, Italy
    Eur J Hum Genet 18:800-7. 2010
    ....
  6. ncbi request reprint Tracing past human male movements in northern/eastern Africa and western Eurasia: new clues from Y-chromosomal haplogroups E-M78 and J-M12
    Fulvio Cruciani
    Dipartimento di Genetica e Biologia Molecolare, Sapienza Universita di Roma, Rome, Italy, and Laboratoire d Immunologie, Hopital de Sainte Marguerite, Marseille, France
    Mol Biol Evol 24:1300-11. 2007
    ..Our results not only provide a refinement of previous evolutionary hypotheses but also well-defined time frames for past human movements both in northern/eastern Africa and western Eurasia...
  7. ncbi request reprint Molecular dissection of the Y chromosome haplogroup E-M78 (E3b1a): a posteriori evaluation of a microsatellite-network-based approach through six new biallelic markers
    Fulvio Cruciani
    Dipartimento di Genetica e Biologia Molecolare, Universita La Sapienza, Rome, Italy
    Hum Mutat 27:831-2. 2006
    ....
  8. doi request reprint Genetic diversity patterns at the human clock gene period 2 are suggestive of population-specific positive selection
    Fulvio Cruciani
    Dipartimento di Genetica e Biologia Molecolare, Sapienza Universita di Roma, Rome, Italy
    Eur J Hum Genet 16:1526-34. 2008
    ..Overall, these findings indicate that a human clock-relevant gene, PER2, might have been influenced by positive selection, and offer preliminary insights into the evolution of this functional class of genes...
  9. ncbi request reprint Recurrent mutation in SNPs within Y chromosome E3b (E-M215) haplogroup: a rebuttal
    Fulvio Cruciani
    Department of Genetics and Molecular Biology, Sapienza Universita di Roma, Rome 00185, Italy
    Am J Hum Biol 20:614-6. 2008
    ..We discuss these results in the frame of general approaches to attain robust phylogenetic inferences based on biallelic polymorphism data...
  10. doi request reprint Footprints of X-to-Y gene conversion in recent human evolution
    Beniamino Trombetta
    Dipartimento di Genetica e Biologia Molecolare, Sapienza Universita di Roma, Rome, Italy
    Mol Biol Evol 27:714-25. 2010
    ..Present data are expected to pave the way for future investigations on the role of nonallelic gene conversion in double-strand break repair and the maintenance of Y chromosome integrity...
  11. pmc Phylogeographic analysis of haplogroup E3b (E-M215) y chromosomes reveals multiple migratory events within and out of Africa
    Fulvio Cruciani
    Dipartimento di Genetica e Biologia Molecolare, Universita La Sapienza, 00185 Rome, Italy
    Am J Hum Genet 74:1014-22. 2004
    ....
  12. pmc A new topology of the human Y chromosome haplogroup E1b1 (E-P2) revealed through the use of newly characterized binary polymorphisms
    Beniamino Trombetta
    Dipartimento di Biologia e Biotecnologie Charles Darwin, Sapienza Universita di Roma, Rome, Italy
    PLoS ONE 6:e16073. 2011
    ..Thirdly, most of the E1b1b1* (E-M35*) paragroup chromosomes are now marked by defining mutations, thus increasing the discriminative power of the haplogroup for use in human evolution and forensics...
  13. ncbi request reprint Brief communication: mtDNA variation in North Cameroon: lack of Asian lineages and implications for back migration from Asia to sub-Saharan Africa
    Valentina Coia
    Department of Animal and Human Biology, University La Sapienza, 00185 Rome, Italy
    Am J Phys Anthropol 128:678-81. 2005
    ....
  14. pmc An unbiased resource of novel SNP markers provides a new chronology for the human Y chromosome and reveals a deep phylogenetic structure in Africa
    Rosaria Scozzari
    Dipartimento di Biologia e Biotecnologie C Darwin, Sapienza Universita di Roma, Rome 00185, Italy
    Genome Res 24:535-44. 2014
    ..e., a period of our evolution that had been previously considered to be poorly accessible with paternally inherited markers. ..
  15. pmc Inter- and intraspecies phylogenetic analyses reveal extensive x-y gene conversion in the evolution of gametologous sequences of human sex chromosomes
    Beniamino Trombetta
    Dipartimento di Biologia e Biotecnologie Charles Darwin, Sapienza Universita di Roma, Roma, Italy
    Mol Biol Evol 31:2108-23. 2014
    ..In turn, intraspecific analysis demonstrates that X-Y gene conversion may modulate human sex-chromosome-sequence evolution to a greater extent than previously thought. ..
  16. doi request reprint Strong intra- and inter-continental differentiation revealed by Y chromosome SNPs M269, U106 and U152
    Fulvio Cruciani
    Dipartimento di Genetica e Biologia Molecolare, Sapienza Universita di Roma, Rome, Italy
    Forensic Sci Int Genet 5:e49-52. 2011
    ..These haplogroups showed quite different frequency distribution patterns within Europe, with frequency peaks in northern Europe (R1b1b2g) and northern Italy/France (R1b1b2h)...
  17. ncbi request reprint Molecular diversity at the CYP2D6 locus in the Mediterranean region
    Silvia Fuselli
    Department of Biology, University of Ferrara, Via Borsari 46, 44100 Ferrara, Italy
    Eur J Hum Genet 12:916-24. 2004
    ....
  18. pmc Y-chromosomal evidence of a pastoralist migration through Tanzania to southern Africa
    Brenna M Henn
    Department of Anthropology, Stanford University, Stanford, CA 94035 2117, USA
    Proc Natl Acad Sci U S A 105:10693-8. 2008
    ..Our Y-chromosomal evidence supports a demic diffusion model of pastoralism from eastern to southern Africa approximately 2,000 years ago...
  19. pmc The molecular dissection of mtDNA haplogroup H confirms that the Franco-Cantabrian glacial refuge was a major source for the European gene pool
    Alessandro Achilli
    Dipartimento di Genetica e Microbiologia, Universita di Pavia, Pavia, Italy
    Am J Hum Genet 75:910-8. 2004
    ..The survey revealed that the previously reported excess of H among these families is caused entirely by H3 and is due to a major, probably nonrecent, founder event...
  20. pmc Africans in Yorkshire? The deepest-rooting clade of the Y phylogeny within an English genealogy
    Turi E King
    Department of Genetics, University of Leicester, Leicester, UK
    Eur J Hum Genet 15:288-93. 2007
    ..Our findings represent the first genetic evidence of Africans among 'indigenous' British, and emphasize the complexity of human migration history as well as the pitfalls of assigning geographical origin from Y-chromosomal haplotypes...
  21. ncbi request reprint The mtDNA legacy of the Levantine early Upper Palaeolithic in Africa
    Anna Olivieri
    Dipartimento di Genetica e Microbiologia, Universita di Pavia, Via Ferrata 1, 27100 Pavia, Italy
    Science 314:1767-70. 2006
    ....
  22. ncbi request reprint Single, rapid coastal settlement of Asia revealed by analysis of complete mitochondrial genomes
    Vincent Macaulay
    Department of Statistics, University of Glasgow, Glasgow G12 8QQ, Scotland, UK
    Science 308:1034-6. 2005
    ..There was an early offshoot, leading ultimately to the settlement of the Near East and Europe, but the main dispersal from India to Australia approximately 65,000 years ago was rapid, most likely taking only a few thousand years...
  23. pmc Extensive female-mediated gene flow from sub-Saharan Africa into near eastern Arab populations
    Martin Richards
    Department of Chemical and Biological Sciences, University of Huddersfield, Huddersfield, United Kingdom
    Am J Hum Genet 72:1058-64. 2003
    ....