Research Topics
Genomes and GenesSpecies | Fulvio CrucianiSummaryAffiliation: University of Rome La Sapienza Country: Italy Publications
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Detail Information
Publications
A back migration from Asia to sub-Saharan Africa is supported by high-resolution analysis of human Y-chromosome haplotypesFulvio Cruciani
Dipartimenti di Genetica e Biologia Molecolare, Universita La Sapienza, Rome, Italy
Am J Hum Genet 70:1197-214. 2002..Haplogroup IX Y chromosomes appear to have been involved in such a migration, the traces of which can now be observed mostly in northern Cameroon...- A revised root for the human Y chromosomal phylogenetic tree: the origin of patrilineal diversity in AfricaFulvio Cruciani
Dipartimento di Biologia e Biotecnologie C Darwin, Sapienza Universita di Roma, Rome 00185, Italy
Am J Hum Genet 88:814-8. 2011..An analysis of 2204 African DNA samples showed that the deepest clades of the revised MSY phylogeny are currently found in central and northwest Africa, opening new perspectives on early human presence in the continent... 
Linkage disequilibrium analysis of the human adenosine deaminase (ada) gene provides evidence for a lack of correlation between hot spots of equal and unequal homologous recombinationFulvio Cruciani
Dipartimento di Genetica e Biologia Molecolare, Universita La Sapienza, P le Aldo Moro 5, 00185 Rome, Italy
Genomics 82:20-33. 2003..This observation provides the first evidence for an absence of correlation between hot spots of equal and unequal homologous recombination...- Human Y chromosome haplogroup R-V88: a paternal genetic record of early mid Holocene trans-Saharan connections and the spread of Chadic languagesFulvio Cruciani
Dipartimento di Genetica e Biologia Molecolare, Sapienza Universita di Roma, Rome, Italy
Eur J Hum Genet 18:800-7. 2010.... 
Recurrent mutation in SNPs within Y chromosome E3b (E-M215) haplogroup: a rebuttalFulvio Cruciani
Department of Genetics and Molecular Biology, Sapienza Universita di Roma, Rome 00185, Italy
Am J Hum Biol 20:614-6. 2008..We discuss these results in the frame of general approaches to attain robust phylogenetic inferences based on biallelic polymorphism data...- Genetic diversity patterns at the human clock gene period 2 are suggestive of population-specific positive selectionFulvio Cruciani
Dipartimento di Genetica e Biologia Molecolare, Sapienza Universita di Roma, Rome, Italy
Eur J Hum Genet 16:1526-34. 2008..Overall, these findings indicate that a human clock-relevant gene, PER2, might have been influenced by positive selection, and offer preliminary insights into the evolution of this functional class of genes... - Tracing past human male movements in northern/eastern Africa and western Eurasia: new clues from Y-chromosomal haplogroups E-M78 and J-M12Fulvio Cruciani
Dipartimento di Genetica e Biologia Molecolare, Sapienza Universita di Roma, Rome, Italy, and Laboratoire d Immunologie, Hopital de Sainte Marguerite, Marseille, France
Mol Biol Evol 24:1300-11. 2007..Our results not only provide a refinement of previous evolutionary hypotheses but also well-defined time frames for past human movements both in northern/eastern Africa and western Eurasia... - Molecular dissection of the Y chromosome haplogroup E-M78 (E3b1a): a posteriori evaluation of a microsatellite-network-based approach through six new biallelic markersFulvio Cruciani
Dipartimento di Genetica e Biologia Molecolare, , Rome, Italy
Hum Mutat 27:831-2. 2006.... - Footprints of X-to-Y gene conversion in recent human evolutionBeniamino Trombetta
Dipartimento di Genetica e Biologia Molecolare, Sapienza Universita di Roma, Rome, Italy
Mol Biol Evol 27:714-25. 2010..Present data are expected to pave the way for future investigations on the role of nonallelic gene conversion in double-strand break repair and the maintenance of Y chromosome integrity... - Phylogeographic analysis of haplogroup E3b (E-M215) y chromosomes reveals multiple migratory events within and out of AfricaFulvio Cruciani
Dipartimento di Genetica e Biologia Molecolare, Universita La Sapienza, 00185 Rome, Italy
Am J Hum Genet 74:1014-22. 2004.... - Brief communication: mtDNA variation in North Cameroon: lack of Asian lineages and implications for back migration from Asia to sub-Saharan AfricaValentina Coia
Department of Animal and Human Biology, University La Sapienza, 00185 Rome, Italy
Am J Phys Anthropol 128:678-81. 2005.... - A new topology of the human Y chromosome haplogroup E1b1 (E-P2) revealed through the use of newly characterized binary polymorphismsBeniamino Trombetta
Dipartimento di Biologia e Biotecnologie Charles Darwin, Sapienza Universita di Roma, Rome, Italy
PLoS ONE 6:e16073. 2011..Thirdly, most of the E1b1b1* (E-M35*) paragroup chromosomes are now marked by defining mutations, thus increasing the discriminative power of the haplogroup for use in human evolution and forensics... - Molecular dissection of the basal clades in the human Y chromosome phylogenetic treeRosaria Scozzari
Dipartimento di Biologia e Biotecnologie Charles Darwin, Sapienza Universita di Roma, Rome, Italy
PLoS ONE 7:e49170. 2012..Our data provide a highly resolved branching in the African-specific portion of the Y tree and support the hypothesis of an origin in the north-western quadrant of the African continent for the human MSY diversity... - Strong intra- and inter-continental differentiation revealed by Y chromosome SNPs M269, U106 and U152Fulvio Cruciani
Dipartimento di Genetica e Biologia Molecolare, Sapienza Universita di Roma, Rome, Italy
Forensic Sci Int Genet 5:e49-52. 2011..These haplogroups showed quite different frequency distribution patterns within Europe, with frequency peaks in northern Europe (R1b1b2g) and northern Italy/France (R1b1b2h)... - The mtDNA legacy of the Levantine early Upper Palaeolithic in AfricaAnna Olivieri
Dipartimento di Genetica e Microbiologia, , Via Ferrata 1, 27100 Pavia, Italy
Science 314:1767-70. 2006.... - Y-chromosomal evidence of a pastoralist migration through Tanzania to southern AfricaBrenna M Henn
Department of Anthropology, Stanford University, Stanford, CA 94035 2117, USA
Proc Natl Acad Sci U S A 105:10693-8. 2008..Our Y-chromosomal evidence supports a demic diffusion model of pastoralism from eastern to southern Africa approximately 2,000 years ago... - Single, rapid coastal settlement of Asia revealed by analysis of complete mitochondrial genomesVincent Macaulay
Department of Statistics, University of Glasgow, Glasgow G12 8QQ, Scotland, UK
Science 308:1034-6. 2005..There was an early offshoot, leading ultimately to the settlement of the Near East and Europe, but the main dispersal from India to Australia approximately 65,000 years ago was rapid, most likely taking only a few thousand years... - The molecular dissection of mtDNA haplogroup H confirms that the Franco-Cantabrian glacial refuge was a major source for the European gene poolAlessandro Achilli
Dipartimento di Genetica e Microbiologia, , Pavia, Italy
Am J Hum Genet 75:910-8. 2004..The survey revealed that the previously reported excess of H among these families is caused entirely by H3 and is due to a major, probably nonrecent, founder event... - Molecular diversity at the CYP2D6 locus in the Mediterranean regionSilvia Fuselli
Department of Biology, University of Ferrara, Via Borsari 46, 44100 Ferrara, Italy
Eur J Hum Genet 12:916-24. 2004.... - Africans in Yorkshire? The deepest-rooting clade of the Y phylogeny within an English genealogyTuri E King
Department of Genetics, University of Leicester, Leicester, UK
Eur J Hum Genet 15:288-93. 2007..Our findings represent the first genetic evidence of Africans among 'indigenous' British, and emphasize the complexity of human migration history as well as the pitfalls of assigning geographical origin from Y-chromosomal haplotypes... - Extensive female-mediated gene flow from sub-Saharan Africa into near eastern Arab populationsMartin Richards
Department of Chemical and Biological Sciences, University of Huddersfield, Huddersfield, United Kingdom
Am J Hum Genet 72:1058-64. 2003....