G Cravotto

Summary

Affiliation: University of Turin
Country: Italy

Publications

  1. ncbi request reprint Umbelliferone aminoalkyl derivatives as inhibitors of oxidosqualene cyclases from Saccharomyces cerevisiae, Trypanosoma cruzi, and Pneumocystis carinii
    Simonetta Oliaro-Bosso
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, 10125 Turin, Italy
    Lipids 39:1007-12. 2004
  2. ncbi request reprint A novel SWCNT platform bearing DOTA and β-cyclodextrin units. "One shot" multidecoration under microwave irradiation
    E Calcio Gaudino
    Dipartimento di Scienza e Tecnologia del Farmaco, and Interdepartmental Centre Nanostructured Interfaces and Surfaces NIS, University of Turin, via P Giuria 9, 10125 Torino, Italy
    Org Biomol Chem 12:4708-15. 2014
  3. doi request reprint On the mechanochemical activation by ultrasound
    Giancarlo Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, via P Giuria 9, I 10125 Torino, Italy
    Chem Soc Rev 42:7521-34. 2013
  4. doi request reprint Enabling technologies for the rapid dechlorination of polychloroarenes and PCBs
    Giancarlo Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, via P Giuria 9, Torino 10125, Italy
    Chemosphere 92:299-303. 2013
  5. doi request reprint Solvent-free chemoselective oxidation of thioethers and thiophenes by mechanical milling
    Giancarlo Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, University of Turin, via P Giuria 9, I 10125 Turin, Italy
    Chem Commun (Camb) 48:11632-4. 2012
  6. ncbi request reprint Novel squalene-hopene cyclase inhibitors derived from hydroxycoumarins and hydroxyacetophenones
    Giancarlo Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, Torino, Italy
    Chem Pharm Bull (Tokyo) 52:1171-4. 2004
  7. ncbi request reprint Regio- and stereoselective reductions of dehydrocholic acid
    Giancarlo Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, via P Giuria 9, 10125 Torino, Italy
    Steroids 71:469-75. 2006
  8. ncbi request reprint Long-chain 3-acyl-4-hydroxycoumarins: structure and antibacterial activity
    Giancarlo Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, Torino, Italy
    Arch Pharm (Weinheim) 339:129-32. 2006
  9. doi request reprint Synthesis of 1-octacosanol and GC-C-IRMS discrimination of samples from different origin
    Giancarlo Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, Torino, Italy
    Nat Prod Res 24:428-39. 2010
  10. doi request reprint Phytotherapeutics: an evaluation of the potential of 1000 plants
    G Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, University of Turin, Turin, Italy
    J Clin Pharm Ther 35:11-48. 2010

Collaborators

Detail Information

Publications58

  1. ncbi request reprint Umbelliferone aminoalkyl derivatives as inhibitors of oxidosqualene cyclases from Saccharomyces cerevisiae, Trypanosoma cruzi, and Pneumocystis carinii
    Simonetta Oliaro-Bosso
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, 10125 Turin, Italy
    Lipids 39:1007-12. 2004
    ..Results identify a particularly promising new family of OSC inhibitors, for the development of novel antiparasitic agents...
  2. ncbi request reprint A novel SWCNT platform bearing DOTA and β-cyclodextrin units. "One shot" multidecoration under microwave irradiation
    E Calcio Gaudino
    Dipartimento di Scienza e Tecnologia del Farmaco, and Interdepartmental Centre Nanostructured Interfaces and Surfaces NIS, University of Turin, via P Giuria 9, 10125 Torino, Italy
    Org Biomol Chem 12:4708-15. 2014
    ..Besides thermogravimetric analyses, the determination of the amount of β-CD and DOTA moieties grafting onto the SWCNT's surface was performed on the basis of phenolphthalein and gadolinium complexation, respectively. ..
  3. doi request reprint On the mechanochemical activation by ultrasound
    Giancarlo Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, via P Giuria 9, I 10125 Torino, Italy
    Chem Soc Rev 42:7521-34. 2013
    ..A series of case studies involving solids, crystals, and polymers illustrate the mechanical properties of sound waves. ..
  4. doi request reprint Enabling technologies for the rapid dechlorination of polychloroarenes and PCBs
    Giancarlo Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, via P Giuria 9, Torino 10125, Italy
    Chemosphere 92:299-303. 2013
    ..In this comparison, high-intensity ultrasound stands out as the technique of choice...
  5. doi request reprint Solvent-free chemoselective oxidation of thioethers and thiophenes by mechanical milling
    Giancarlo Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, University of Turin, via P Giuria 9, I 10125 Turin, Italy
    Chem Commun (Camb) 48:11632-4. 2012
    ..6 eq.) under solventless mechanical milling conditions. This green procedure has been efficiently applied to a series of model compounds and to the desulphurization of medium/high sulphur content paraffins (up to 3000 mg kg(-1))...
  6. ncbi request reprint Novel squalene-hopene cyclase inhibitors derived from hydroxycoumarins and hydroxyacetophenones
    Giancarlo Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, Torino, Italy
    Chem Pharm Bull (Tokyo) 52:1171-4. 2004
    ..Derivatives bearing an omega-epoxyfarnesyl moiety or just a plain alkyl chain showed an inhibitory effect on a recombinant SHC from Alicyclobacillus acidocaldarius expressed in Escherichia coli...
  7. ncbi request reprint Regio- and stereoselective reductions of dehydrocholic acid
    Giancarlo Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, via P Giuria 9, 10125 Torino, Italy
    Steroids 71:469-75. 2006
    ..1)H and (13)C resonances were assigned in details thanks to a series of 1D and 2D NMR runs including DEPT, NOESY, H-H COSY, gHSQC and gHMBC...
  8. ncbi request reprint Long-chain 3-acyl-4-hydroxycoumarins: structure and antibacterial activity
    Giancarlo Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, Torino, Italy
    Arch Pharm (Weinheim) 339:129-32. 2006
    ..A newly synthesized 2-acyl derivative of 2H-indene-1,3-dione containing the same tricarbonylmethane motif showed a comparable activity...
  9. doi request reprint Synthesis of 1-octacosanol and GC-C-IRMS discrimination of samples from different origin
    Giancarlo Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, Torino, Italy
    Nat Prod Res 24:428-39. 2010
    ....
  10. doi request reprint Phytotherapeutics: an evaluation of the potential of 1000 plants
    G Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, University of Turin, Turin, Italy
    J Clin Pharm Ther 35:11-48. 2010
    ..The aim is to provide broad coverage of as many potentially useful plants as possible and then to focus on those with the greatest therapeutic potential...
  11. ncbi request reprint The combined use of microwaves and ultrasound: improved tools in process chemistry and organic synthesis
    Giancarlo Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, Via Giuria 9, 10125 Turin, Italy
    Chemistry 13:1902-9. 2007
    ..By using selected examples, this concept article gives an overview of apparatus currently available for simultaneous or tandem irradiation and explains how it can be utilized in organic synthesis and analysis...
  12. doi request reprint Oxidative degradation of chlorophenol derivatives promoted by microwaves or power ultrasound: a mechanism investigation
    Giancarlo Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, University of Turin, 10125, Turin, Italy
    Environ Sci Pollut Res Int 17:674-87. 2010
    ....
  13. doi request reprint Molecular self-assembly and patterning induced by sound waves. The case of gelation
    Giancarlo Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, via P Giuria 9, I 10125 Torino, Italy
    Chem Soc Rev 38:2684-97. 2009
    ..Given the importance of supramolecular assemblies, especially hydrogels, as biomaterials and vehicles for drug transport and delivery, sound waves thus provide a facile entry to new forms of soft matter and functionalized materials...
  14. ncbi request reprint Forcing and controlling chemical reactions with ultrasound
    Giancarlo Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, Via Giuria 9, 10125 Torino, Italy
    Angew Chem Int Ed Engl 46:5476-8. 2007
  15. ncbi request reprint Decontamination of soil containing POPs by the combined action of solid Fenton-like reagents and microwaves
    Giancarlo Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, via P Giuria 9, 10125 Torino, Italy
    Chemosphere 69:1326-9. 2007
    ..Results showed that 4-chloronaphthol, 2,4-dichlorophenoxyacetic acid and p-nonylphenol had been degraded completely, 2,4-dibromophenol to a large extent...
  16. ncbi request reprint Preparation of second generation ionic liquids by efficient solvent-free alkylation of N-heterocycles with chloroalkanes
    Giancarlo Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, Via Giuria 9, 10125 Torino, Italy
    Molecules 13:149-56. 2008
    ..The observed high yields (usually 70-98% isolated), and short reaction times showed that a straightforward access to ILs can be also achieved with the use of alkyl chlorides, resulting in a considerable reduction of costs...
  17. doi request reprint Sonication-assisted fabrication and post-synthetic modifications of graphene-like materials
    Giancarlo Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, Via Giuria 9, 10125 Torino, Italy
    Chemistry 16:5246-59. 2010
    ..This minireview provides some fundamentals on the interaction of sound waves with matter and equally illustrates how sonication assists further synthetic decorations under benign conditions...
  18. ncbi request reprint Power ultrasound in organic synthesis: moving cavitational chemistry from academia to innovative and large-scale applications
    Giancarlo Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, via P Giuria 9, I 10125 Torino, Italy
    Chem Soc Rev 35:180-96. 2006
    ..151 references.)...
  19. doi request reprint A new cyclodextrin-grafted viscose loaded with aescin formulations for a cosmeto-textile approach to chronic venous insufficiency
    G Cravotto
    University of Turin, Turin, Italy
    J Mater Sci Mater Med 22:2387-95. 2011
    ..This cost effective cosmeto-textile shows excellent application compliance and is easily recharged and so has the strong base characteristics needed for possible industrial production...
  20. ncbi request reprint The Suzuki homocoupling reaction under high-intensity ultrasound
    Giancarlo Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, Via Giuria 9, 10125 Torino, Italy
    Ultrason Sonochem 12:91-4. 2005
    ..Besides offering a number of operational advantages, the use of HIU broadens the field of application for the Suzuki reaction...
  21. ncbi request reprint Chemical modification of chitosan under high-intensity ultrasound
    Giancarlo Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, Via Giuria 9, 10125 Torino, Italy
    Ultrason Sonochem 12:95-8. 2005
    ..Compared to conventional methods, all these reactions went to completion in considerably shorter times at lower temperatures...
  22. ncbi request reprint Umbelliferone aminoalkyl derivatives, a new class of squalene-hopene cyclase inhibitors
    Giancarlo Cravotto
    Dip to di Scienza e Tecnologia del Farmaco, Universita di Torino, Via Giuria 9, 10125 Turin, Italy
    Eur J Med Chem 39:917-24. 2004
    ..35 mM), an effective inhibitor of both squalene- and oxidosqualene-cyclases (OSC). Tests are in progress to determine their efficacy on different eukaryotic OSCs...
  23. doi request reprint Efficient synthetic protocols in glycerol under heterogeneous catalysis
    Giancarlo Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita degli Studi di Torino, via P Giuria 9, 10125 Torino, Italy
    ChemSusChem 4:1130-4. 2011
    ..In all cases glycerol proved to be a greener, less expensive, and safer alternative to the classic volatile organic solvents...
  24. ncbi request reprint Improved extraction of vegetable oils under high-intensity ultrasound and/or microwaves
    Giancarlo Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, via P Giuria 9, 10125 Torino, Italy
    Ultrason Sonochem 15:898-902. 2008
    ..9%. Our results indicate that US and MW, either alone or combined, can greatly improve the extraction of bioactive substances, achieving higher efficiency and shorter reaction times at low or moderate costs, with minimal added toxicity...
  25. doi request reprint Extraction of kiwi seed oil: Soxhlet versus four different non-conventional techniques
    Giancarlo Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, 10125 Torino, Italy
    Nat Prod Res 25:974-81. 2011
    ..All these non-conventional techniques are fast, effective and safe. A sensory evaluation test showed the presence of off-flavours in oil samples extracted by Soxhlet and US, an indicator of partial degradation...
  26. doi request reprint Synthesis of water-soluble multidentate aminoalcohol β-cyclodextrin derivatives via epoxide opening
    K Martina
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, via P Giuria 9, 10125 Torino, Italy
    Carbohydr Res 346:2677-82. 2011
    ..A regioselective epoxide opening reaction was observed in the reaction with styrene oxide while the stereoselectivity was strictly dependent on substrate structure...
  27. ncbi request reprint Degradation of persistent organic pollutants by Fenton's reagent facilitated by microwave or high-intensity ultrasound
    G Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, Via Giuria 9, 10125 Torino, Italy
    Environ Technol 26:721-4. 2005
    ..Acidification with acetic acid (pH 2.0-2.3) did not affect the process, but sulphuric acid (pH 1.7-2.0) facilitated complete degradation. Thus, compared to conventional methods, US and MW processes are faster and much more efficient...
  28. ncbi request reprint Farnesyloxycoumarins, a new class of squalene-hopene cyclase inhibitors
    Giancarlo Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, Via Giuria 9, I 10125 Turin, Italy
    Bioorg Med Chem Lett 14:1931-4. 2004
    ..Umbelliprenin-10',11'-monoepoxide (IC(50) 2.5 microM) and the corresponding 6',7'-10',11' diepoxide (IC(50) 1.5 microM) were the most active enzyme inhibitors...
  29. ncbi request reprint Azomethine ylide cycloaddition/reductive heterocyclization approach to oxindole alkaloids: asymmetric synthesis of (-)-horsfiline
    G Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, , Via Giuria 9, 0125 Torino, Italy
    J Org Chem 66:8447-53. 2001
    ....
  30. doi request reprint New asymmetrical per-substituted cyclodextrins (2-O-methyl-3-O-ethyl- and 2-O-ethyl-3-O-methyl-6-O-t-butyldimethylsilyl-beta-derivatives) as chiral selectors for enantioselective gas chromatography in the flavour and fragrance field
    Carlo Bicchi
    Dipartimento di Scienza e Tecnologia del Farmaco, Facolta di Farmacia, Universita degli Studi di Torino, Via Pietro Giuria 9, Turin 10125, Italy
    J Chromatogr A 1217:1106-13. 2010
    ..Moreover, these new CD derivatives with better enantioselectivity are also shown to be very useful in routine analysis for the exhaustive control of samples containing several chiral characterizing markers in a single run...
  31. ncbi request reprint Umbelliferone aminoalkyl derivatives as inhibitors of human oxidosqualene-lanosterol cyclase
    Simonetta Oliaro-Bosso
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita degli Studi di Torino, Turin, Italy
    J Enzyme Inhib Med Chem 24:589-98. 2009
    ..Molecular docking analyses, carried out to clarify details of inhibitors/enzyme interactions, proved useful to explain the observed differences in inhibitory activities...
  32. ncbi request reprint New chiral selectors: design and synthesis of 6-TBDMS-2,3-methyl beta-cyclodextrin 2-2' thioureido dimer and 6-TBDMS-2,3-methyl (or 2-methyl-3-acetyl) beta-cyclodextrin bearing an (R) Mosher acid moiety
    Giancarlo Cravotto
    Universita di Torino, Dipartimento di Scienza e Tecnologia del Farmaco, Turin, Italy
    Chirality 16:526-33. 2004
    ..A computational study of model structures to design these CD derivatives...
  33. ncbi request reprint New paramagnetic supramolecular adducts for MRI applications based on non-covalent interactions between Gd(III)-complexes and beta- or gamma-cyclodextrin units anchored to chitosan
    Silvio Aime
    Dipartimento di Chimica, IFM, Universita di Torino, Via Giuria 7, 10125 Torino, Italy
    J Inorg Biochem 100:931-8. 2006
    ....
  34. ncbi request reprint Inhibitory effect of umbelliferone aminoalkyl derivatives on oxidosqualene cyclases from S. cerevisiae, T. cruzi, P. carinii, H. sapiens, and A. thaliana: a structure-activity study
    Simonetta Oliaro-Bosso
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita degli Studi di Torino, via P Giuria 9, 10125 Turin, Italy
    ChemMedChem 2:226-33. 2007
    ..The remarkable activities of three compounds on the T. cruzi enzyme and of five of them on the P. carinii enzyme suggest the present series as a promising compound family for the development of novel antiparasitic agents...
  35. ncbi request reprint Daucane phytoestrogens: a structure-activity study
    Giovanni Appendino
    Dipartimento di Scienze Chimiche, Alimentari, Farmaceutiche e Farmacologiche, Universita del Piemonte Orientale, Viale Ferrucci 33, 28100 Novara, Italy
    J Nat Prod 65:1612-5. 2002
    ..Homologation and vinylation were both detrimental for activity, as were methylation of the p-hydroxyl substituent and the introduction of oxygen functions on the adjacent carbons...
  36. ncbi request reprint A straightforward synthesis in aqueous medium of enantiomerically. Enriched S(-)2,2'-dihydroxy-1,1'-binaphthyl
    Francesco Trotta
    Dipartimento di Chimica Inorganica, Chimica Fisica e Chimica dei Materiali dell Universitiá di Torino, Via Pietro Giuria 7, 1 10125 Torino, Italy
    Environ Sci Pollut Res Int 10:144-6. 2003
    ..This one-pot synthesis do not require any organic solvents and oxidising metal cations...
  37. ncbi request reprint How to determine free Gd and free ligand in solution of Gd chelates. A technical note
    Alessandro Barge
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, via P Giuria 9 10125 Torino, Italy
    Contrast Media Mol Imaging 1:184-8. 2006
    ..Herein the currently used procedures that allow an assessment of the amounts of free metal ions and free ligand in a solution of a given Gd complex are described in detail...
  38. doi request reprint Efficient microwave-assisted synthetic protocols and in silico behaviour prediction of per-substituted β-cyclodextrins
    K Martina
    Dipartimento di Scienza e Tecnologia del Farmaco, University of Turin, Via Pietro Giuria 9, 10125 Torino, Italy
    Org Biomol Chem 11:5521-7. 2013
    ..Our strategy is supported by computational analyses which were used to estimate the physicochemical behaviour of per-substituted derivatives and to tailor suitable substituents. ..
  39. ncbi request reprint Improved syntheses of bis(beta-cyclodextrin) derivatives, new carriers for gadolinium complexes
    Silvio Aime
    Dipartimento di Chimica I F M, Universita di Torino, Via Giuria 7, 10125, Torino, Italy
    Org Biomol Chem 4:1124-30. 2006
    ..3 x 10(4) M(-1)vs 8.0 x 10(2) M(-1)). Relaxivity increased as well by factors of 3 and 4, viz. from 9.1 mM(-1) s(-1) (beta-CD) to 27.7 and 35 mM(-1) s(-1)...
  40. doi request reprint New cyclodextrin dimers and trimers capable of forming supramolecular adducts with shape-specific ligands
    Silvio Aime
    Dipartimento di Chimica IFM, Universita di Torino, Via Giuria 7, 10125 Torino, Italy
    Org Biomol Chem 7:370-9. 2009
    ..These inclusion complexes were found to be 2 to 3 orders of magnitude more stable than those formed by betaCD and to be endowed with high relaxivity values...
  41. ncbi request reprint Oxygenated sesquiterpenoids from a nonpoisonous sardinian chemotype of giant fennel (Ferula communis)
    G Appendino
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, Via Giuria 9, 10125 Torino, Italy
    J Nat Prod 64:393-5. 2001
    ..A number of known compounds were also identified. Despite the lack of morphological differences, a broad chemical diversity exists within giant fennel, underlying the contrasting data on its poisonous properties...
  42. doi request reprint Bifunctional ligands based on the DOTA-monoamide cage
    Alessandro Barge
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, Via Giuria, 9 10125, Torino, Italy
    Org Biomol Chem 6:1176-84. 2008
    ..Bioconjugates obtained in this way can be used for diagnostic imaging and therapeutic applications...
  43. doi request reprint Synthesis, characterization and potential application of monoacyl-cyclodextrins
    Katia Martina
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, Via Giuria 9, 10125 Torino, Italy
    Carbohydr Res 345:191-8. 2010
    ..1)H, (13)C and 2D NMR experiments could easily discriminate the position of the ester. Monoacylated CDs were evaluated as a carrier of silibinin, the inclusion complexes were prepared and characterized by thermal analysis...
  44. ncbi request reprint Chemical modifications of bile acids under high-intensity ultrasound or microwave irradiation
    Giancarlo Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, Via Giuria 9, 10125 Torino, Italy
    Steroids 70:77-83. 2005
    ..Compared to conventional methods, both techniques proved much more efficient, increasing product yields and dramatically cutting down reaction times. Scaled-up studies are now under way...
  45. ncbi request reprint A degradation product of halobetasol propionate: characterization and structure
    Giancarlo Cravotto
    Dipartimento di Scienza e Tecnologia del Farmaco, Via Giuria 9, 10125, Torino, Italy
    Steroids 72:787-91. 2007
    ..Degradation of halobetasol propionate was observed in the presence of bases. A single cyclization product was isolated and fully characterized by MS, NMR and X-ray crystallography...
  46. doi request reprint Microwave-assisted Maillard reactions for the preparation of advanced glycation end products (AGEs)
    Sonja Visentin
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, via P Giuria 9, 10125 Torino, Italy
    Org Biomol Chem 8:2473-7. 2010
    ..In this paper we present a new rapid and efficient one-pot procedure for the preparation of pentosidine and other AGEs under microwave irradiation...
  47. ncbi request reprint The combination of oxalic acid with power ultrasound fully degrades chrysotile asbestos fibres
    Francesco Turci
    Dipartimento di Chimica IFM, Interdepartmental Centre G Scansetti for Studies on Asbestos and Other Toxic Particulates and Centre of Excellence of Nanostructured Interfaces and Surface, University of Torino, Torino, Italy
    J Environ Monit 9:1064-6. 2007
    ..The simultaneous action of power ultrasound and oxalic acid, as a chelating agent, rapidly converts chrysotile asbestos into water soluble material and a non-asbestos debris, not classifiable as hazardous under worldwide safety regulations...
  48. ncbi request reprint A new approach to the decontamination of asbestos-polluted waters by treatment with oxalic acid under power ultrasound
    Francesco Turci
    Dipartimento di Chimica IFM, Interdepartmental Centre G Scansetti for Studies on Asbestos and Other Toxic Particulates and Centre of Excellence of Nanostructured Interfaces and Surface, University of Torino, Via Pietro Giuria 7, 10125 Torino, Italy
    Ultrason Sonochem 15:420-7. 2008
    ..Furthermore, as the length of these antigorite fibrils lay outside the fibre range rated as a health hazard under worldwide regulations, our procedure can be employed for the decontamination of chrysotile-polluted waters and sediments...
  49. doi request reprint Synthesis of functionalised HP-DO3A chelating agents for conjugation to biomolecules
    Alessandro Barge
    Dipartimento di Scienza e Tecnologia del Farmaco, Universita di Torino, Via Giuria 9, 10125 Torino, Italy
    Org Biomol Chem 7:3810-6. 2009
    ....
  50. doi request reprint New detoxification processes for asbestos fibers in the environment
    Francesco Turci
    Interdepartmental Centre G Scansetti for Studies on Asbestos and Other Toxic Particulates, University of Torino, Torino, Italy
    J Toxicol Environ Health A 73:368-77. 2010
    ..Thus, data indicated the proposed method was effective in detoxifying waterborne chrysotile asbestos fibers...
  51. doi request reprint Regulation of HMGCoA reductase activity by policosanol and octacosadienol, a new synthetic analogue of octacosanol
    Simonetta Oliaro-Bosso
    Dipartimento di Scienza e Tecnologia del Farmaco, University of Torino, Via Giuria 9, 10125, Torino, Italy
    Lipids 44:907-16. 2009
    ..Octacosadienol was as effective as policosanol in inhibiting the upregulation of HMGCoA reductase, in inducing the phosphorylation of AMPK and in downregulating the HMGCoA reductase mRNA...
  52. doi request reprint Tuning glutamine binding modes in Gd-DOTA-based probes for an improved MRI visualization of tumor cells
    Rachele Stefania
    Dipartmento di Chimica IFM and Molecular Imaging Center, Universita di Torino, Via Nizza 52, 10125 Torino, Italy
    Chemistry 15:76-85. 2009
    ..The observed behavior is rationalized in terms of the exploitation of an additional glutamine transporter active in hepatic tumor cells...
  53. ncbi request reprint Ln(III)-DOTAMGly complexes: a versatile series to assess the determinants of the efficacy of paramagnetic chemical exchange saturation transfer agents for magnetic resonance imaging applications
    Enzo Terreno
    Dipartimento di Chimica IFM, Universita di Torino, Torino, Italy
    Invest Radiol 39:235-43. 2004
    ..Their ability to reduce the water signal intensity depends on the interplay of several physico-chemical properties of the agent and instrumental parameters. This study aims to identify possible routes for their optimization..
  54. ncbi request reprint Mineralisation of 2,4-dichlorophenoxyacetic acid by acoustic or hydrodynamic cavitation in conjunction with the advanced Fenton process
    David H Bremner
    School of Contemporary Sciences, University of Abertay Dundee, Bell Street, Dundee DD1 1HG Scotland, UK
    Ultrason Sonochem 15:416-9. 2008
    ..After 20 min of treatment the residual TOC is reduced to 30% and this probably represents the remaining highly recalcitrant small organic molecules...
  55. ncbi request reprint Ultrasonic evidence of hydrophobic interactions. Effect of ultrasound on benzoin condensation and some other reactions in aqueous ethanol
    Ants Tuulmets
    Institute of Organic and Bioorganic Chemistry, University of Tartu, Jakobi 2, 51014 Tartu, Estonia
    J Phys Chem B 111:3133-8. 2007
    ..When it suppresses the stabilization of the encounter complexes between reagents, sonication hinders the reaction but accelerates it when it perturbs the hydrophobic stabilization of the ground state of a reagent...
  56. ncbi request reprint Chemistry and biological activity of natural and synthetic prenyloxycoumarins
    Massimo Curini
    Dipartimento di Chimica e Tecnologia del Farmaco, Sezione di Chimica Organica, Via del Liceo, 06123 Perugia, Italy
    Curr Med Chem 13:199-222. 2006
    ..The object of this review is to examine in detail the different types of prenyloxycoumarins and prenyloxyfuranocoumarins from the chemical, phytochemical and biological point of view...
  57. ncbi request reprint Effect of ultrasound on the base-catalyzed hydrolysis of 4-nitrophenyl acetate in aqueous ethanol
    Siim Salmar
    Institute of Organic and Bioorganic Chemistry, University of Tartu, Jakobi 2, 51014 Tartu, Estonia
    J Phys Chem B 110:5817-21. 2006
    ..This conclusion seems to apply to both acid-catalyzed and base-catalyzed hydrolysis reactions. Parallel experiments with a titanium horn revealed the catalytic action of undetermined chemical species formed from dispersed titanium metal...
  58. ncbi request reprint Synthesis, docking studies and anti-inflammatory activity of 4,5,6,7-tetrahydro-2H-indazole derivatives
    Ornelio Rosati
    Dipartimento di Chimica e Tecnologia del Farmaco, Via del Liceo 1, University of Perugia, 06123 Perugia PG, Italy
    Bioorg Med Chem 15:3463-73. 2007
    ..Noteworthy, both compounds evidenced the lack of any gastric injury even at high doses in gastric ulcerogenic assays...