Antonio Cossu

Summary

Affiliation: University of Sassari
Country: Italy

Publications

  1. pmc Phase III randomized study of fotemustine and dacarbazine versus dacarbazine with or without interferon-α in advanced malignant melanoma
    Antonio Daponte
    Department of Melanoma, Istituto Nazionale Tumori Fondazione Pascale, Via Mariano Semmola, 80131, Naples, Italy
    J Transl Med 11:38. 2013
  2. pmc Effect of dabrafenib on melanoma cell lines harbouring the BRAF(V600D/R) mutations
    Giusy Gentilcore
    Department Melanoma, Istituto Nazionale Tumori Fondazione Pascale, Naples, Italy
    BMC Cancer 13:17. 2013
  3. pmc A role of BRCA1 and BRCA2 germline mutations in breast cancer susceptibility within Sardinian population
    Grazia Palomba
    Istituto Chimica Biomolecolare CNR, Trav La Crucca Baldinca Li Punti, 07100 Sassari, Italy
    BMC Cancer 9:245. 2009
  4. pmc Serial detection of circulating tumour cells by reverse transcriptase-polymerase chain reaction assays is a marker for poor outcome in patients with malignant melanoma
    Giuseppe Palmieri
    Istituto di Chimica Biomolecolare Consiglio Nazionale Ricerche, Li Punti Sassari, Italy
    BMC Cancer 6:266. 2006
  5. pmc Origin and distribution of the BRCA2-8765delAG mutation in breast cancer
    Grazia Palomba
    Istituto di Chimica Biomolecolare Consiglio Nazionale Ricerche, Sassari, Italy
    BMC Cancer 7:132. 2007
  6. pmc Molecular alterations in key-regulator genes among patients with T4 breast carcinoma
    Bruno Massidda
    Department of Medical Oncology, University of Cagliari, Cagliari, Italy
    BMC Cancer 10:458. 2010
  7. ncbi request reprint Synchronous interdigitating dendritic cell sarcoma and B-cell small lymphocytic lymphoma in a lymph node
    Antonio Cossu
    Institutes of Anatomic Pathology and Histopathology, University of Sassari, Sassari, Italy
    Arch Pathol Lab Med 130:544-7. 2006
  8. ncbi request reprint Classic follicular dendritic reticulum cell tumor of the lymph node developing in a patient with a previous inflammatory pseudotumor-like proliferation
    Antonio Cossu
    Institute of Anatomic Pathology and Histopathology, University of Sassari, 07100 Sassaru, Italy
    Hum Pathol 36:207-11. 2005
  9. ncbi request reprint Nephrotic syndrome and angiotropic lymphoma report of a case
    Antonio Cossu
    Azienda USL n 1 Sassari, Istituto di Anatomia ed Istologia Patologica, Sassari, Italy
    Tumori 90:510-3. 2004
  10. doi request reprint Unexpected distribution of cKIT and BRAF mutations among southern Italian patients with sinonasal melanoma
    Maria Colombino
    Unit of Cancer Genetics, Institute of Biomolecular Chemistry, CNR, University of Sassari, Sassari, Italy
    Dermatology 226:279-84. 2013

Collaborators

Detail Information

Publications20

  1. pmc Phase III randomized study of fotemustine and dacarbazine versus dacarbazine with or without interferon-α in advanced malignant melanoma
    Antonio Daponte
    Department of Melanoma, Istituto Nazionale Tumori Fondazione Pascale, Via Mariano Semmola, 80131, Naples, Italy
    J Transl Med 11:38. 2013
    ..The effect of the addition of fotemustine and/or interferon (IFN) to standard therapy with dacarbazine alone in patients with advanced malignant melanoma was investigated in a multicenter, randomized 2x2 factorial design trial...
  2. pmc Effect of dabrafenib on melanoma cell lines harbouring the BRAF(V600D/R) mutations
    Giusy Gentilcore
    Department Melanoma, Istituto Nazionale Tumori Fondazione Pascale, Naples, Italy
    BMC Cancer 13:17. 2013
    ..We here tested dabrafenib for its capability to inhibit cell growth on primary melanoma cell lines, established from patients' tumour tissues and carrying the BRAFV600D/R mutations...
  3. pmc A role of BRCA1 and BRCA2 germline mutations in breast cancer susceptibility within Sardinian population
    Grazia Palomba
    Istituto Chimica Biomolecolare CNR, Trav La Crucca Baldinca Li Punti, 07100 Sassari, Italy
    BMC Cancer 9:245. 2009
    ..The occurrence of phenotypic characteristics which may be predictive for the presence of BRCA1-2 germline mutations was also evaluated...
  4. pmc Serial detection of circulating tumour cells by reverse transcriptase-polymerase chain reaction assays is a marker for poor outcome in patients with malignant melanoma
    Giuseppe Palmieri
    Istituto di Chimica Biomolecolare Consiglio Nazionale Ricerche, Li Punti Sassari, Italy
    BMC Cancer 6:266. 2006
    ..We here evaluated the prognostic role of RT-PCR assays in serially-taken peripheral blood samples from patients with malignant melanoma (MM)...
  5. pmc Origin and distribution of the BRCA2-8765delAG mutation in breast cancer
    Grazia Palomba
    Istituto di Chimica Biomolecolare Consiglio Nazionale Ricerche, Sassari, Italy
    BMC Cancer 7:132. 2007
    ..We evaluated both the prevalence of the BRCA2-8765delAG variant in Sardinia and the putative existence of a common ancestral origin through a haplotype analysis of breast cancer family members carrying such a mutation...
  6. pmc Molecular alterations in key-regulator genes among patients with T4 breast carcinoma
    Bruno Massidda
    Department of Medical Oncology, University of Cagliari, Cagliari, Italy
    BMC Cancer 10:458. 2010
    ..We here evaluated the clinical role of some molecular alterations involved in tumorigenesis in a well-characterized cohort of T4 breast cancer patients with a long follow-up period...
  7. ncbi request reprint Synchronous interdigitating dendritic cell sarcoma and B-cell small lymphocytic lymphoma in a lymph node
    Antonio Cossu
    Institutes of Anatomic Pathology and Histopathology, University of Sassari, Sassari, Italy
    Arch Pathol Lab Med 130:544-7. 2006
    ..A possible relationship between the 2 disorders is also discussed...
  8. ncbi request reprint Classic follicular dendritic reticulum cell tumor of the lymph node developing in a patient with a previous inflammatory pseudotumor-like proliferation
    Antonio Cossu
    Institute of Anatomic Pathology and Histopathology, University of Sassari, 07100 Sassaru, Italy
    Hum Pathol 36:207-11. 2005
    ..The nodule was removed, and a diagnosis of a classic FDRCT of the lymph node was made. The present case is remarkable, and clinicopathological data show that IPT-like proliferations could be in some case an early presentation of FDRCT...
  9. ncbi request reprint Nephrotic syndrome and angiotropic lymphoma report of a case
    Antonio Cossu
    Azienda USL n 1 Sassari, Istituto di Anatomia ed Istologia Patologica, Sassari, Italy
    Tumori 90:510-3. 2004
    ..This case and our review of the literature suggest that the rare association of intravascular lymphoma and glomerular disease is more than coincidental...
  10. doi request reprint Unexpected distribution of cKIT and BRAF mutations among southern Italian patients with sinonasal melanoma
    Maria Colombino
    Unit of Cancer Genetics, Institute of Biomolecular Chemistry, CNR, University of Sassari, Sassari, Italy
    Dermatology 226:279-84. 2013
    ..Racial and geographic factors seem to affect the incidence of cutaneous and mucosal melanoma...
  11. pmc Heterogeneous distribution of BRAF/NRAS mutations among Italian patients with advanced melanoma
    Maria Colombino
    Unit of Cancer Genetics, Institute of Biomolecular Chemistry ICB, National Research Council CNR, Traversa La Crucca 3, Baldinca Li Punti 07100, Sassari, Italy
    J Transl Med 11:202. 2013
    ..Prevalence and distribution of pathogenetic mutations in BRAF and NRAS genes were evaluated in multiple melanoma lesions from patients with different geographical origin within the same Italian population...
  12. pmc Epidemiology of thyroid cancer in an area of epidemic thyroid goiter
    Antonio Cossu
    Department of Surgical, Microsurgical and Medical Sciences, University of Sassari, Via le San Pietro 43B, 07100 Sassari, Italy
    J Cancer Epidemiol 2013:584768. 2013
    ..Women are affected earlier than men and, therefore, suffer greater professional, economic, and social impacts. Overall mortality is low and a relative 5-year survival is excellent, especially in comparison to other malignancies...
  13. doi request reprint Anaplastic large cell lymphoma of the breast arising around mammary implant capsule: an Italian report
    Francesco Farace
    Plastic Surgery Unit, Department of Surgery, Microsurgery and Medical Sciences, University Hospital Trust, University of Sassari, Viale San Pietro 43, Sassari, Italy
    Aesthetic Plast Surg 37:567-71. 2013
    ..We strongly suggest considering ALCL in any patient with a spontaneous breast seroma lasting more than 6 months after mammary prosthesis implantation. The suspicion of ALCL must be suggested to the pathologist immediately...
  14. pmc Prevalence of KRAS, BRAF, and PIK3CA somatic mutations in patients with colorectal carcinoma may vary in the same population: clues from Sardinia
    Grazia Palomba
    Istituto di Chimica Biomolecolare, CNR, Sassari, Italy
    J Transl Med 10:178. 2012
    ..In this population-based study, we evaluated the incidence rates and distribution of such somatic mutations in genetically isolated population from Sardinia...
  15. pmc Role of key-regulator genes in melanoma susceptibility and pathogenesis among patients from South Italy
    Milena Casula
    Istituto di Chimica Biomolecolare, Consiglio Nazionale delle Ricerche, Sassari, Italy
    BMC Cancer 9:352. 2009
    ..Several genetic alterations have been demonstrated to contribute to the development and progression of melanoma. In this study, we further investigated the impact of key-regulator genes in susceptibility and pathogenesis of such a disease...
  16. doi request reprint Molecular analysis of Fanconi anemia and mismatch repair genes in patients with colorectal carcinoma
    Maria Colombino
    Istituto di Chimica Biomolecolare CNR, Sassari, Italy
    Oncol Rep 25:899-904. 2011
    ....
  17. pmc Role of BRCA2 mutation status on overall survival among breast cancer patients from Sardinia
    Mario Budroni
    Registro Tumori di Sassari, ASL 1, Sassari, Italy
    BMC Cancer 9:62. 2009
    ..In this study, we investigated the role of such mutations on breast cancer-specific survival among patients from North Sardinia...
  18. ncbi request reprint Distribution and significance of 14-3-3sigma, a novel myoepithelial marker, in normal, benign, and malignant breast tissue
    Peter T Simpson
    The Breakthrough Toby Robins Breast Cancer Research Centre, Institute of Cancer Research, London, UK
    J Pathol 202:274-85. 2004
    ..This analysis demonstrates the utility of 14-3-3sigma as a new adjunct antibody for characterization of myoepithelial cells and myoepithelial lesions and it may be a novel prognostic factor for breast cancer patients...
  19. ncbi request reprint Prognostic value of circulating melanoma cells detected by reverse transcriptase-polymerase chain reaction
    Giuseppe Palmieri
    Institute of Genetics of Populations, Consiglio Nazionale delle Ricerche, Alghero Sassari, Italy
    J Clin Oncol 21:767-73. 2003
    ..Two main questions were addressed: first, whether the presence of CMCs, defined as the patient being positive for any of the three markers, had a prognostic role; and second, what the predictive value of each individual marker was...