A Cossarizza

Summary

Affiliation: University of Modena and Reggio Emilia
Country: Italy

Publications

  1. pmc Quercetin and cancer chemoprevention
    Lara Gibellini
    Department of Biomedical Sciences, University of Modena and Reggio Emilia School of Medicine, 41125 Modena, Italy
    Evid Based Complement Alternat Med 2011:591356. 2011
  2. doi request reprint Cytometry, immunology, and HIV infection: three decades of strong interactions
    Andrea Cossarizza
    Department of Surgery, Medicine, Dentistry and Morphological Sciences, University of Modena and Reggio Emilia, Modena, Italy
    Cytometry A 83:680-91. 2013
  3. pmc T cell activation but not polyfunctionality after primary HIV infection predicts control of viral load and length of the time without therapy
    Andrea Cossarizza
    Department of Surgery, Medicine, Dentistry and Morphological Sciences, University of Modena and Reggio Emilia, Modena, Italy
    PLoS ONE 7:e50728. 2012
  4. pmc CD4saurus Rex &HIVelociraptor vs. development of clinically useful immunological markers: a Jurassic tale of frozen evolution
    Andrea De Maria
    Centro di Eccellenza per la Ricerca Biomedica, Universita di Genova, Genova, Italy
    J Transl Med 9:93. 2011
  5. doi request reprint Simultaneous analysis of reactive oxygen species and reduced glutathione content in living cells by polychromatic flow cytometry
    Andrea Cossarizza
    Department of Biomedical Sciences, University of Modena and Reggio Emilia, Modena, Italy
    Nat Protoc 4:1790-7. 2009
  6. ncbi request reprint Increased plasma levels of extracellular mitochondrial DNA during HIV infection: a new role for mitochondrial damage-associated molecular patterns during inflammation
    Andrea Cossarizza
    Department of Biomedical Sciences, University of Modena and Reggio Emilia, Via Campi 287, 41125 Modena, Italy
    Mitochondrion 11:750-5. 2011
  7. ncbi request reprint Use of flow cytometry as a tool to study mitochondrial membrane potential in isolated, living hepatocytes
    S Salvioli
    Department of Biomedical Sciences, Section of General Pathology, University of Modena, Via Campi, 287, 41100 Modena, Italy
    Biochemistry (Mosc) 63:235-8. 1998
  8. ncbi request reprint MMP-7 promoter polymorphisms do not influence CD4+ recovery and changes in plasma viral load during antiretroviral therapy for HIV-1 infection
    E Lugli
    Department of Biomedical Sciences, Chair of Immunology, University of Modena and Reggio Emilia, 41100 Modena, Italy
    Int J Immunogenet 32:269-71. 2005
  9. ncbi request reprint Apoptotic features of peripheral blood granulocytes and monocytes during primary, acute HIV infection
    A Cossarizza
    Department of Biomedical Sciences, Section of General Pathology, University of Modena School of Medicine, Via Campi 287, Modena, 41100, Italy
    Exp Cell Res 247:304-11. 1999
  10. ncbi request reprint Tests for mitochondrial function and DNA: potentials and pitfalls
    Andrea Cossarizza
    Department of Biomedical Sciences, Section of General Pathology, University of Modena, Modena, Italy
    Curr Opin Infect Dis 16:5-10. 2003

Collaborators

Detail Information

Publications57

  1. pmc Quercetin and cancer chemoprevention
    Lara Gibellini
    Department of Biomedical Sciences, University of Modena and Reggio Emilia School of Medicine, 41125 Modena, Italy
    Evid Based Complement Alternat Med 2011:591356. 2011
    ..In this review we discuss the molecular mechanisms that are based on the biological effects of Qu, and their relevance for human health...
  2. doi request reprint Cytometry, immunology, and HIV infection: three decades of strong interactions
    Andrea Cossarizza
    Department of Surgery, Medicine, Dentistry and Morphological Sciences, University of Modena and Reggio Emilia, Modena, Italy
    Cytometry A 83:680-91. 2013
    ....
  3. pmc T cell activation but not polyfunctionality after primary HIV infection predicts control of viral load and length of the time without therapy
    Andrea Cossarizza
    Department of Surgery, Medicine, Dentistry and Morphological Sciences, University of Modena and Reggio Emilia, Modena, Italy
    PLoS ONE 7:e50728. 2012
    ..Our objective was to characterize the polyfunctionality of immune response triggered by PHI, and to characterize immune activation and regulatory T cells, correlating such features to disease progression...
  4. pmc CD4saurus Rex &HIVelociraptor vs. development of clinically useful immunological markers: a Jurassic tale of frozen evolution
    Andrea De Maria
    Centro di Eccellenza per la Ricerca Biomedica, Universita di Genova, Genova, Italy
    J Transl Med 9:93. 2011
    ..The scientific and clinical community needs an effort in stimulating clinical evolution of immunological tests beyond "CD4saurus Rex" introducing new parameters in the clinical arena after appropriate validation...
  5. doi request reprint Simultaneous analysis of reactive oxygen species and reduced glutathione content in living cells by polychromatic flow cytometry
    Andrea Cossarizza
    Department of Biomedical Sciences, University of Modena and Reggio Emilia, Modena, Italy
    Nat Protoc 4:1790-7. 2009
    ..This approach is extremely useful to study the balance between ROS content and antioxidants in cells receiving different stimuli, and to analyze the relationship between oxidative stress and cell death...
  6. ncbi request reprint Increased plasma levels of extracellular mitochondrial DNA during HIV infection: a new role for mitochondrial damage-associated molecular patterns during inflammation
    Andrea Cossarizza
    Department of Biomedical Sciences, University of Modena and Reggio Emilia, Via Campi 287, 41125 Modena, Italy
    Mitochondrion 11:750-5. 2011
    ....
  7. ncbi request reprint Use of flow cytometry as a tool to study mitochondrial membrane potential in isolated, living hepatocytes
    S Salvioli
    Department of Biomedical Sciences, Section of General Pathology, University of Modena, Via Campi, 287, 41100 Modena, Italy
    Biochemistry (Mosc) 63:235-8. 1998
    ..The results indicate that the proposed method may be used in laboratory practice...
  8. ncbi request reprint MMP-7 promoter polymorphisms do not influence CD4+ recovery and changes in plasma viral load during antiretroviral therapy for HIV-1 infection
    E Lugli
    Department of Biomedical Sciences, Chair of Immunology, University of Modena and Reggio Emilia, 41100 Modena, Italy
    Int J Immunogenet 32:269-71. 2005
    ..We evaluated whether two polymorphisms in MMP-7 promoter could influence CD4+ recover in response to antiretroviral therapy, and found that these polymorphisms are ineffective...
  9. ncbi request reprint Apoptotic features of peripheral blood granulocytes and monocytes during primary, acute HIV infection
    A Cossarizza
    Department of Biomedical Sciences, Section of General Pathology, University of Modena School of Medicine, Via Campi 287, Modena, 41100, Italy
    Exp Cell Res 247:304-11. 1999
    ....
  10. ncbi request reprint Tests for mitochondrial function and DNA: potentials and pitfalls
    Andrea Cossarizza
    Department of Biomedical Sciences, Section of General Pathology, University of Modena, Modena, Italy
    Curr Opin Infect Dis 16:5-10. 2003
    ....
  11. ncbi request reprint Characterization of cells with different mitochondrial membrane potential during apoptosis
    Enrico Lugli
    Department of Biomedical Sciences, Chair of Immunology, University of Modena and Reggio Emilia, Modena, Italy
    Cytometry A 68:28-35. 2005
    ..Using polychromatic flow cytometry based upon multiple laser and UV lamp excitation, we have characterized cells with different DeltaPsi during apoptosis...
  12. ncbi request reprint Essential requirement of reduced glutathione (GSH) for the anti-oxidant effect of the flavonoid quercetin
    Roberta Ferraresi
    University of Modena and Reggio Emilia School of Medicine, Department of Biomedical Sciences, Italy
    Free Radic Res 39:1249-58. 2005
    ..Thus, QU can exert different effects (anti-/prooxidant) depending on exposure times and oxidative balance, and in particular on stores of GSH...
  13. doi request reprint Absence of liver steatosis in HIV-HCV co-infected patients receiving regimens containing tenofovir or abacavir
    V Borghi
    Clinic of Infectious and Tropical Diseases, Azienda Ospedaliero Universitaria Policlinico di Modena, University of Modena and Reggio Emilia, Via del Pozzo, 71, 41100, Modena, Italy
    Infection 41:425-9. 2013
    ..We retrospectively investigated the presence of steatosis among HIV-HCV co-infected and HCV mono-infected patients, and the role of tenofovir disoproxil fumarate (TDF) or abacavir (ABC) in determining hepatic steatosis...
  14. ncbi request reprint Mitochondria in the pathogenesis of lipodystrophy induced by anti-HIV antiretroviral drugs: actors or bystanders?
    A Cossarizza
    Department of Biomedical Sciences, University of Modena and Reggio Emilia School of Medicine, Modena, Italy
    Bioessays 23:1070-80. 2001
    ..In this paper, we review data concerning the role of mitochondria in the pathogenesis of lipodystrophy, and advance a unifying hypothesis involving either direct or indirect effects of the drugs employed during HAART...
  15. ncbi request reprint T cell homeostasis in centenarians: from the thymus to the periphery
    M Pinti
    Department of Biomedical Sciences, University of Modena and Reggio Emilia, Italy
    Curr Pharm Des 16:597-603. 2010
    ..Data on the possible use of these molecules, including cytokines like interleukin (IL)-7, IL-15 and keratinocyte growth factor, to restore thymic function are reviewed and discussed...
  16. ncbi request reprint Flow cytometric analysis of mitochondrial membrane potential using JC-1
    A Cossarizza
    University of Modena, Modena, Italy
    Curr Protoc Cytom . 2001
    ..A valuable component of this measurement system is the possibility of making quantitative measurements of changes in membrane potential...
  17. ncbi request reprint Apoptosis and HIV infection: about molecules and genes
    Andrea Cossarizza
    Chair of Immunology, University of Modena and Reggio Emilia School of Medicine, Italy
    Curr Pharm Des 14:237-44. 2008
    ..The role of the host genetic background is finally crucial in understanding the process of cell death in HIV infection...
  18. ncbi request reprint Mitochondria, HIV infection and its treatment: where do we go from here?
    Andrea Cossarizza
    University of Modena and Reggio Emilia, Modena, Italy
    Antivir Ther 10:M1-2. 2005
  19. ncbi request reprint Biological importance of the two Toll-like receptors, TLR2 and TLR4, in macrophage response to infection with Candida albicans
    Elisabetta Blasi
    Department of Hygiene, Microbiology and Biostatistical Sciences, University of Modena and Reggio Emilia, Via Campi 287, 41100 Modena, Italy
    FEMS Immunol Med Microbiol 44:69-79. 2005
    ..albicans appears to be TLR4 but not TLR2-dependent...
  20. doi request reprint Herpes simplex virus type 1 dysregulates anti-fungal defenses preventing monocyte activation and downregulating toll-like receptor-2
    Claudio Cermelli
    Department of Public Health Sciences, University of Modena and Reggio Emilia, Modena, Italy
    Microbiol Immunol 52:575-84. 2008
    ....
  21. ncbi request reprint The human immunodeficiency virus (HIV) protease inhibitor indinavir directly affects the opportunistic fungal pathogen Cryptococcus neoformans
    Elisabetta Blasi
    Dipartimento di Scienze Igienistiche, Microbiologiche e Biostatistiche, Via Campi 287, 41100 Modena, Italy
    FEMS Immunol Med Microbiol 42:187-95. 2004
    ..neoformans, these data add new in vitro insights on the wide-spectrum efficacy of PIs, further arguing for the clinical relevance of HAART against opportunistic infections in AIDS...
  22. ncbi request reprint CD4 cell-monitored treatment interruption in patients with a CD4 cell count > 500 x 106 cells/l
    Cristina Mussini
    Clinic of Infectious and Tropical Diseases, Azienda Ospedaliero Universitaria Policlinico, University of Modena and Reggio Emilia, Via del Pozzo, 71, 41100 Modena, Italy
    AIDS 19:287-94. 2005
    ..Little is known about CD4 cell count changes in patients with high CD4 cell counts who interrupt antiretroviral therapy, especially in those with a nadir of 250-350 x 10 cells/l...
  23. ncbi request reprint Protective effect of acetyl-L-carnitine against oxidative stress induced by antiretroviral drugs
    Roberta Ferraresi
    Department of Biomedical Sciences, Section of General Pathology, University of Modena and Reggio Emilia, School of Medicine, Via Campi 287, 41100 Modena, Italy
    FEBS Lett 580:6612-6. 2006
    ..These data suggest that one of these effects could be a direct anti-oxidant action...
  24. ncbi request reprint Effect of treatment interruption monitored by CD4 cell count on mitochondrial DNA content in HIV-infected patients: a prospective study
    Cristina Mussini
    Clinic of Infectious and Tropical Diseases, University of Modena and Reggio Emilia, Modena, Italy
    AIDS 19:1627-33. 2005
    ..HIV infection per se and HAART can alter mitochondrial functionality, leading to a decrease in mitochondrial DNA content...
  25. doi request reprint Resistance of mtDNA-depleted cells to apoptosis
    Roberta Ferraresi
    Department of Biomedical Sciences, University of Modena and Reggio Emilia, Modena, Italy
    Cytometry A 73:528-37. 2008
    ..The resistance to apoptosis of rho(0) cells could be not only due to an increased scavenger capacity of GSH, but also due to a selection of multidrug resistant cells that hyperexpress P-gp...
  26. doi request reprint Randomized trial to evaluate cardiometabolic and endothelial function in patients with plasma HIV-1 RNA suppression switching to darunavir/ritonavir with or without nucleoside analogues
    G Guaraldi
    University of Modena and Reggio Emilia, Modena, Italy
    HIV Clin Trials 14:140-8. 2013
    ..We performed a study to evaluate change in cardiometabolic and endothelial function in HIV-infected patients switching to darunavir/ritonavir (DRV/r) monotherapy versus triple therapy...
  27. ncbi request reprint Magnitude and determinants of CD4 recovery after HAART resumption after 1 cycle of treatment interruption
    Cristina Mussini
    Clinic of Infectious Diseases, University of Modena and Reggio Emilia, Modena, Italy
    J Acquir Immune Defic Syndr 52:588-94. 2009
    ..The extent of immune reconstitution following HAART resumption after 1 cycle of treatment interruption (TI) is not well known...
  28. ncbi request reprint Highly active antiretroviral therapy restores CD4+ Vbeta T-cell repertoire in patients with primary acute HIV infection but not in treatment-naive HIV+ patients with severe chronic infection
    Andrea Cossarizza
    Department of Biomedical Sciences, Section of General Pathology, University of Modena and Reggio Emilia School of Medicine, Modena, Italy
    J Acquir Immune Defic Syndr 35:213-22. 2004
    ..Our results indicate that HAART can restore the T-cell repertoire in individuals whose immune system is not severely compromised by the infection...
  29. doi request reprint Predictive value of intracellular HIV-1 DNA levels during CD4-guided treatment interruption in HIV+ patients
    Milena Nasi
    Department of Biomedical Sciences, University of Modena and Reggio Emilia, Modena, Italy
    AIDS Res Hum Retroviruses 26:553-8. 2010
    ..In conclusion, intracellular HIV-1 DNA is a predictive marker for the length of CD4-guided TI...
  30. ncbi request reprint Anti-HIV drugs and the mitochondria
    Marcello Pinti
    Department of Biomedical Sciences, Section of General Pathology, University of Modena and Reggio Emilia School of Medicine, Via Campi 287, 41100 Modena, Italy
    Biochim Biophys Acta 1757:700-7. 2006
    ....
  31. ncbi request reprint Mitochondrial functionality and mitochondrial DNA content in lymphocytes of vertically infected human immunodeficiency virus-positive children with highly active antiretroviral therapy-related lipodystrophy
    Andrea Cossarizza
    Department of Biomedical Sciences, Section of General Pathology, University of Modena and Reggio Emilia School of Medicine, 41100 Modena, Italy
    J Infect Dis 185:299-305. 2002
    ..mtDNA content was also similar in PBL of LD-positive children and HCs, suggesting that normal mt functionality and normal tendency to undergo apoptosis are present in PBL of children with HAART-associated LD...
  32. ncbi request reprint Kinetics of CD4 cells after discontinuation of antiretroviral therapy in patients with virological failure and a CD4 cell count greater than 500 cells/microl
    Cristina Mussini
    Clinic of Infectious and Tropical Diseases, University of Modena and Reggio Emilia, Modena, Italy
    AIDS 16:1551-4. 2002
    ..This decline was unrelated to the CD4 cell count and HIV-RNA values at interruption, but was more profound in patients in whom the M184V mutation had disappeared after lamivudine discontinuation...
  33. ncbi request reprint Features of 'CD4-exploders', HIV-positive patients with an optimal immune reconstitution after potent antiretroviral therapy
    Cristina Mussini
    Infectious Diseases Clinic, University of Modena and Reggio Emilia School of Medicine and Azienda Ospedaliera Policlinico Modena, Modena, Italy
    AIDS 16:1609-16. 2002
    ..To identify crucial immunological characteristics of a group of patients, defined 'CD4-exploders', who were able to fully reconstitute their immune system after receiving highly active antiretroviral therapy (HAART)...
  34. ncbi request reprint Immunophenotype of HIV+ patients during CD4 cell-monitored treatment interruption: role of the IL-7/IL-7 receptor system
    Elisa Nemes
    Department of Biomedical Sciences, University of Modena and Reggio Emilia, Modena, Italy
    AIDS 20:2021-32. 2006
    ..To investigate immunological changes during CD4-guided therapy interruption in HIV(+) patients who suspended HAART...
  35. ncbi request reprint Different sensitivity to apoptosis in cells of monocytic or lymphocytic origin chronically infected with human immunodeficiency virus type-1
    Marcello Pinti
    Department of Biomedical Sciences, Section of General Pathology, University of Modena and Reggio Emilia School of Medicine, Modena, Italy
    Exp Biol Med (Maywood) 228:1346-54. 2003
    ..However, further studies on ex-vivo collected fresh cells, as well as on other cell lines, are urgently needed to confirm such hypothesis...
  36. ncbi request reprint Genetic polymorphisms of Fas (CD95) and Fas ligand (CD178) influence the rise in CD4+ T cell count after antiretroviral therapy in drug-naïve HIV-positive patients
    Milena Nasi
    Department of Biomedical Sciences, Chair of Immunology, University of Modena and Reggio Emilia, Via Campi 287, Modena, 41100, Italy
    Immunogenetics 57:628-35. 2005
    ....
  37. ncbi request reprint Hepatoma HepG2 cells as a model for in vitro studies on mitochondrial toxicity of antiviral drugs: which correlation with the patient?
    M Pinti
    Department of Biomedical Sciences, Section of General Pathology, University of Modena and Reggio Emilia School of Medicine, Modena, Italy
    J Biol Regul Homeost Agents 17:166-71. 2003
    ....
  38. ncbi request reprint Ceramide 2 (N-acetyl sphingosine) is associated with reduction in Bcl-2 protein levels by Western blotting and with apoptosis in cultured human keratinocytes
    A Di Nardo
    Departments of Dermatology and Biomedical Sciences, University of Modena and Reggio Emilia, Via del Pozzo 71, 41100 Modena, Italy
    Br J Dermatol 143:491-7. 2000
    ..In the skin, the generation of intracellular ceramide may also provide a link between an extracellular signal and the induction of the apoptosis programme for the elimination of damaged cells...
  39. ncbi request reprint Polychromatic analysis of mitochondrial membrane potential using JC-1
    Enrico Lugli
    Department of Biomedical Sciences, General Pathology Section, University of Modena and Reggio Emilia, Modena, Italy
    Curr Protoc Cytom . 2007
    ....
  40. ncbi request reprint Increased mitochondrial DNA content in peripheral blood lymphocytes from HIV-infected patients with lipodystrophy
    Andrea Cossarizza
    Department of Biomedical Sciences, Section of General Pathology, University of Modena and Reggio Emilia School of Medicine, Modena, Italy
    Antivir Ther 8:315-21. 2003
    ..However, further studies are needed to confirm these initial observations and ascertain whether the quantification of mtDNA in PBL is a useful and reliable marker to investigate and monitor HAART-related changes in fat distribution...
  41. doi request reprint Investigating T cells by polychromatic flow cytometry
    Enrico Lugli
    Department of Biomedical Sciences, Section of General Pathology, Modena, Italy
    Methods Mol Biol 514:47-63. 2009
    ..Protocols for performing PFC will be discussed in this chapter, together with some guidelines for data interpretation and analysis...
  42. ncbi request reprint MDR1 C3435T genetic polymorphism does not influence the response to antiretroviral therapy in drug-naive HIV-positive patients
    Milena Nasi
    Department of Biomedical Sciences, University of Modena and Reggio Emilia School of Medicine, Via Campi 287, 41100 Modena, Italy
    AIDS 17:1696-8. 2003
    ..The MDR1 C3435Tpolymorphism did not influence response to therapy, suggesting no disadvantages for individuals with a different genotype...
  43. doi request reprint Homeostatic cytokines and expansion of regulatory T cells accompany thymic impairment in children with Down syndrome
    Erika Roat
    Department of Biomedical Sciences, University of Modena and Reggio Emilia, Modena, Italy
    Rejuvenation Res 11:573-83. 2008
    ....
  44. ncbi request reprint Altered mitochondrial RNA production in adipocytes from HIV-infected individuals with lipodystrophy
    Lorenzo Galluzzi
    Chair of Immunology, Department of Biomedical Sciences, University of Modena and Reggio Emilia, Modena, Italy
    Antivir Ther 10:M91-9. 2005
    ..To further investigate mt changes during this syndrome, we analysed the expression of mtRNA in adipocytes from lipodystrophic HIV+ patients taking NRTI-containing HAART and compared it with similar cells from healthy individuals...
  45. ncbi request reprint Discontinuation of maintenance therapy for cryptococcal meningitis in patients with AIDS treated with highly active antiretroviral therapy: an international observational study
    Cristina Mussini
    Clinic of Infectious and Tropical Diseases, University of Modena and Reggio Emilia, Azienda Policlinico, Modena, Italy
    Clin Infect Dis 38:565-71. 2004
    ..Recurrent cryptococcal infection should be suspected in patients whose serum cryptococcal antigen test results revert back to positive after discontinuation of maintenance therapy...
  46. ncbi request reprint Discontinuation of secondary prophylaxis for Pneumocystis carinii pneumonia in human immunodeficiency virus-infected patients: a randomized trial by the CIOP Study Group
    Cristina Mussini
    Clinic of Infectious and Tropical Diseases, Azienda Ospedaliera Policlinico, University of Modena and Reggio Emilia, Modena, Italy
    Clin Infect Dis 36:645-51. 2003
    ..Patients who present with symptoms after discontinuation of secondary prophylaxis should be evaluated for PCP despite high CD4 count and complete virus suppression...
  47. ncbi request reprint Balanced regulation of mRNA production for Fas and Fas ligand in lymphocytes from centenarians: how the immune system starts its second century
    Marcello Pinti
    Department of Biomedical Sciences, Chair of Immunology, University of Modena and Reggio Emilia, Modena, Italy
    Circulation 110:3108-14. 2004
    ....
  48. ncbi request reprint Subject classification obtained by cluster analysis and principal component analysis applied to flow cytometric data
    Enrico Lugli
    Department of Biomedical Sciences, Chair of Immunology, University of Modena and Reggio Emilia, Via Campi 287, 41100 Modena, Italy
    Cytometry A 71:334-44. 2007
    ..Here we show the use of cluster analysis (CA) and principal component analyses (PCA) to simplify multicolor data visualization and to allow subjects' classification...
  49. ncbi request reprint Identification and characterization of an aspartyl protease from Cryptococcus neoformans
    Marcello Pinti
    Department of Biomedical Sciences, Chair of Immunology, University of Modena and Reggio Emilia, Via Campi 287, 41100 Modena, Italy
    FEBS Lett 581:3882-6. 2007
    ..The transcriptional level of cnap1 in C. neoformans is constant in different media. The absence of any inhibition activity by PIs suggests that other targets for PIs might exist in C. neoformans...
  50. ncbi request reprint Multiparametric analysis of cells with different mitochondrial membrane potential during apoptosis by polychromatic flow cytometry
    Leonarda Troiano
    Department of Biomedical Sciences, University of Modena and Reggio Emilia, Via Campi 287, 41100 Modena, Italy
    Nat Protoc 2:2719-27. 2007
    ..The procedure can be completed in less than 2 h...
  51. doi request reprint Mitochondrial DNA haplogroups and highly active antiretroviral therapy-related lipodystrophy
    Milena Nasi
    Department of Biomedical Sciences, University of Modena and Reggio Emilia, Italy
    Clin Infect Dis 47:962-8. 2008
    ....
  52. doi request reprint Quercetin inhibits lymphocyte activation and proliferation without inducing apoptosis in peripheral mononuclear cells
    Enrico Lugli
    Department of Biomedical Sciences, Chair of Immunology, University of Modena and Reggio Emilia, Via Campi 287, 41100 Modena, Italy
    Leuk Res 33:140-50. 2009
    ..Our data suggest that quercetin, while incapable of inducing apoptosis in normal cells under several conditions, could interfere with effector T cell function...
  53. ncbi request reprint HIV coinfection and antiretroviral therapy enhances liver steatosis in patients with hepatitis C, but only in those infected by HCV genotype other than 3
    Vanni Borghi
    Clinic of Infectious and Tropical Diseases, University of Modena and Reggio Emilia, Modena, Italy
    Antivir Ther 13:1057-65. 2008
    ..We analysed the effect of HIV coinfection and antiretroviral therapy on hepatic steatosis and the effect of the steatosis on fibrosis in patients with or without HCV genotype 3 infection...
  54. pmc HOXD13 binds DNA replication origins to promote origin licensing and is inhibited by geminin
    Valentina Salsi
    Department of Animal Biology, University of Modena and Reggio Emilia, Via G Campi 213 d, Modena 41100, Italy
    Mol Cell Biol 29:5775-88. 2009
    ..Our results uncover a function for Hox proteins in the regulation of replication origin activity and reveal an unforeseen role for the inhibition of HOX protein activity by geminin in the context of replication origin licensing...
  55. ncbi request reprint Complementary and alternative medicine during HIV infection
    Milena Nasi
    University of Modena and Reggio Emilia, Dept of Biomedical Sciences, Section of General Pathology, Via Campi 287, 41100 Modena, Italy
    Adv Exp Med Biol 546:105-10. 2004
  56. ncbi request reprint Mitochondrial alterations and tendency to apoptosis in peripheral blood cells from children with Down syndrome
    Erika Roat
    Chair of Immunology, Department of Biomedical Sciences, University of Modena and Reggio Emilia, Via Campi 287, 41100 Modena, Italy
    FEBS Lett 581:521-5. 2007
    ..However, in cells from DS subjects, mitochondria showed a higher loss of DeltaPsi(m), underlying the presence of an increasing susceptibility of these organelles to damaging agents...