Detail Information
Publications
l-Threonine aldolase, serine hydroxymethyltransferase and fungal alanine racemase. A subgroup of strictly related enzymes specialized for different functionsR Contestabile
Dipartimento di Scienze Biochimiche A Rossi Fanelli and Centro di Biologia Molecolare del Consiglio Nazionale delle Ricerche, Universita degli Studi di Roma, La Sapienza, Roma, Italy
Eur J Biochem 268:6508-25. 2001..coli and alanine racemase from Cochliobolus carbonum, and their comparison with the SHMT crystal structure, indicated how the tetrahydrofolate binding site might have evolved and offered a starting point for further investigations...
Role of tyrosine 65 in the mechanism of serine hydroxymethyltransferaseR Contestabile
Dipartimento di Scienze Biochimiche A Rossi Fanelli and Centro di Biologia Molecolare del Consiglio Nazionale delle Ricerche, Universita La Sapienza, Roma, Italy
Biochemistry 39:7492-500. 2000..These data are consistent with a role for the Tyr65 hydroxyl group in the conversion of a closed active site to an open structure...
