Carlo Colosimo

Summary

Affiliation: University of Rome La Sapienza
Country: Italy

Publications

  1. doi request reprint Nonmotor presentations of multiple system atrophy
    Carlo Colosimo
    Department of Neurology and Psychiatry, Sapienza University of Rome, Viale dell Universita 30, 00185 Rome, Italy
    Nat Rev Neurol 7:295-8. 2011
  2. ncbi request reprint Efficacy and safety of long-term botulinum toxin treatment in craniocervical dystonia: a systematic review
    Carlo Colosimo
    Dipartimento di Neurologia e Psichiatria, Sapienza Universita di Roma, Viale dell Universita 30, 00185 Rome, Italy
    Neurotox Res 22:265-73. 2012
  3. doi request reprint A further case of nicotine sensitivity in multiple system atrophy
    Carlo Colosimo
    Dipartimento di Neurologia e Psichiatria, Sapienza Universita di Roma, Italy
    Clin Neuropharmacol 35:51-2. 2012
  4. doi request reprint Task force report on scales to assess dyskinesia in Parkinson's disease: critique and recommendations
    Carlo Colosimo
    Department of Neurological Sciences and Neuromed Institute, Sapienza University of Rome, Rome, Italy
    Mov Disord 25:1131-42. 2010
  5. doi request reprint An early image of hemifacial spasm: Edouard Brissaud contribution
    Carlo Colosimo
    Department of Neurological Sciences and Neuromed Institute, Sapienza University of Rome, Rome, Italy
    Mov Disord 25:531-3. 2010
  6. doi request reprint Non-motor symptoms in atypical and secondary parkinsonism: the PRIAMO study
    Carlo Colosimo
    Dipartimento di Scienze Neurologiche, Sapienza Universita di Roma, Rome, Italy
    J Neurol 257:5-14. 2010
  7. ncbi request reprint Noradrenergic drugs for levodopa-induced dyskinesia
    Carlo Colosimo
    Department of Neurological Science University La Sapienza, Viale dell Universita 30, I 00185 Rome, Italy
    Clin Neuropharmacol 26:299-305. 2003
  8. ncbi request reprint Drug Insight: new drugs in development for Parkinson's disease
    Carlo Colosimo
    University Department of Neurosciences University of Rome, La Sapienza, Italy
    Nat Clin Pract Neurol 2:600-10. 2006
  9. ncbi request reprint Lack of association between progressive supranuclear palsy and arterial hypertension: a clinicopathological study
    Carlo Colosimo
    Dipartimento di Scienze Neurologiche, Universita La Sapienza, Rome, Italy
    Mov Disord 18:694-7. 2003
  10. ncbi request reprint The symptomatic treatment of multiple system atrophy
    C Colosimo
    Dipartimento di Scienze Neurologiche, Universita La Sapienza, Rome, Italy
    Eur J Neurol 9:195-9. 2002

Detail Information

Publications48

  1. doi request reprint Nonmotor presentations of multiple system atrophy
    Carlo Colosimo
    Department of Neurology and Psychiatry, Sapienza University of Rome, Viale dell Universita 30, 00185 Rome, Italy
    Nat Rev Neurol 7:295-8. 2011
    ..The importance of recognizing such symptoms should not be underestimated, being crucial for understanding the disease prognosis, avoiding unnecessary tests and procedures, and planning any therapeutic intervention...
  2. ncbi request reprint Efficacy and safety of long-term botulinum toxin treatment in craniocervical dystonia: a systematic review
    Carlo Colosimo
    Dipartimento di Neurologia e Psichiatria, Sapienza Universita di Roma, Viale dell Universita 30, 00185 Rome, Italy
    Neurotox Res 22:265-73. 2012
    ..Longitudinal studies aimed at defining the risk factors for this abnormal pattern of response to botulinum toxin treatment are currently being conducted...
  3. doi request reprint A further case of nicotine sensitivity in multiple system atrophy
    Carlo Colosimo
    Dipartimento di Neurologia e Psichiatria, Sapienza Universita di Roma, Italy
    Clin Neuropharmacol 35:51-2. 2012
    ..Further studies are warranted to investigate the prevalence of nicotine sensitivity in MSA and shed light on its neurochemical substrate...
  4. doi request reprint Task force report on scales to assess dyskinesia in Parkinson's disease: critique and recommendations
    Carlo Colosimo
    Department of Neurological Sciences and Neuromed Institute, Sapienza University of Rome, Rome, Italy
    Mov Disord 25:1131-42. 2010
    ..As further testing of these scales in PD is warranted, no new scales are needed until the available scales are fully tested clinimetrically...
  5. doi request reprint An early image of hemifacial spasm: Edouard Brissaud contribution
    Carlo Colosimo
    Department of Neurological Sciences and Neuromed Institute, Sapienza University of Rome, Rome, Italy
    Mov Disord 25:531-3. 2010
    ..We also discuss the role of other early European authors (Schültze, Gowers, Babinski, and Negro) who contributed to the definition of hemifacial spasm in the late 19th and early 20th centuries...
  6. doi request reprint Non-motor symptoms in atypical and secondary parkinsonism: the PRIAMO study
    Carlo Colosimo
    Dipartimento di Scienze Neurologiche, Sapienza Universita di Roma, Rome, Italy
    J Neurol 257:5-14. 2010
    ..Atypical parkinsonism patients also reported a low QoL, with no significant differences among the different forms, whereas PD and VP patients had a better QoL...
  7. ncbi request reprint Noradrenergic drugs for levodopa-induced dyskinesia
    Carlo Colosimo
    Department of Neurological Science University La Sapienza, Viale dell Universita 30, I 00185 Rome, Italy
    Clin Neuropharmacol 26:299-305. 2003
    ....
  8. ncbi request reprint Drug Insight: new drugs in development for Parkinson's disease
    Carlo Colosimo
    University Department of Neurosciences University of Rome, La Sapienza, Italy
    Nat Clin Pract Neurol 2:600-10. 2006
    ..In this Review, we discuss the numerous drugs in development that target the primary motor disorder in Parkinson's disease...
  9. ncbi request reprint Lack of association between progressive supranuclear palsy and arterial hypertension: a clinicopathological study
    Carlo Colosimo
    Dipartimento di Scienze Neurologiche, Universita La Sapienza, Rome, Italy
    Mov Disord 18:694-7. 2003
    ..60; 95% confidence interval, 0.20-1.76). Therefore, HT does not represent an important clinical feature of this neurodegenerative disorder, although cerebrovascular disease can masquerade clinically as PSP...
  10. ncbi request reprint The symptomatic treatment of multiple system atrophy
    C Colosimo
    Dipartimento di Scienze Neurologiche, Universita La Sapienza, Rome, Italy
    Eur J Neurol 9:195-9. 2002
    ..The treatment of the very common genito-urinary symptoms (incontinence, retention, impotence) should also be considered in order to improve the quality of life of these patients...
  11. pmc Diffusion tensor imaging in primary cervical dystonia
    C Colosimo
    Department of Neurological Sciences, University La Sapienza, I 00185 Rome, Italy
    J Neurol Neurosurg Psychiatry 76:1591-3. 2005
    ..It is the traditional view that primary dystonia arises from abnormal basal ganglia function but causes no apparent morphological changes...
  12. doi request reprint Onset and spread of dyskinesias and motor symptoms in Parkinson's disease
    Giovanni Fabbrini
    Department of Neurological Sciences and Neuromed Institute, Sapienza University of Rome, Rome, Italy
    Mov Disord 24:2091-6. 2009
    ..In this group, clinical examination yielded a significantly different distribution of LID and motor symptoms. These findings suggest that the onset and spread of LID and motor symptoms may follow different anatomical patterns...
  13. doi request reprint Abnormal cortical synaptic plasticity in primary motor area in progressive supranuclear palsy
    Antonella Conte
    Department of Neurology and Psychiatry Sapienza, University of Rome, Viale dell Universita, 30, 00185 Rome, Italy
    Cereb Cortex 22:693-700. 2012
    ..The iTBS-induced abnormal MEP facilitation in PSP persisted at 1-year follow-up. In conclusion, patients with PSP have abnormal M1 LTP/LTD-like plasticity. The enhanced LTP-like cortical synaptic plasticity parallels disease progression...
  14. ncbi request reprint Mirror movements in patients with Parkinson's disease
    Donatella Ottaviani
    Department of Neurological Sciences and Neuromed Institute IRCCS, La Sapienza University of Rome, Rome, Italy
    Mov Disord 23:253-8. 2008
    ..16, P < 0.01). The low frequency of MM in PD probably relates to the complex interactions between the pathophysiological mechanisms leading to parkinsonian signs and the mechanisms responsible for movement lateralization...
  15. doi request reprint Psychiatric disorders in adult-onset focal dystonia: a case-control study
    Giovanni Fabbrini
    Department of Neurological Sciences and Neuromed Institute, Sapienza University of Rome, Rome, Italy
    Mov Disord 25:459-65. 2010
    ..The most common psychiatric features in patients with CD and BPS are depressive disorders...
  16. doi request reprint Voluntary, spontaneous and reflex blinking in patients with clinically probable progressive supranuclear palsy
    Matteo Bologna
    Department of Neurological Sciences, Sapienza, University of Rome, Rome, Italy
    Brain 132:502-10. 2009
    ..Abnormal voluntary, spontaneous and reflex blinking in patients with PSP reflects the widespread cortical, subcortical and brainstem degeneration related to this disease...
  17. ncbi request reprint Prevalence and clinical features of hedonistic homeostatic dysregulation in Parkinson's disease
    Francesca Romana Pezzella
    Department of Neurological Sciences, La Sapienza University, Rome, Italy
    Mov Disord 20:77-81. 2005
    ..Of interest, our patients showed a somewhat different pattern of the disorder, suggesting that cultural and environmental factors may play a role in the phenomenology of HHD...
  18. doi request reprint Effect of camptocormia on lung volumes in Parkinson's disease
    Paolo Marinelli
    Department of Public Health and Infectious Diseases, Sapienza University of Rome, Italy
    Respir Physiol Neurobiol 187:164-6. 2013
    ..45° and supine) measurement of arterial oxygen-hemoglobin saturation and heart rate. We found that Parkinson's disease with camptocormia is not associated with major clinical changes in lung volumes...
  19. ncbi request reprint A comparative study of primary and secondary hemifacial spasm
    Carlo Colosimo
    Department of Neurosciences and Neuromed Institute, University of Rome La Sapienza, Rome, Italy
    Arch Neurol 63:441-4. 2006
    ..Hemifacial spasm (HFS) is a common movement disorder...
  20. doi request reprint No association between essential tremor and migraine: a case-control study
    Piero Barbanti
    Headache and Pain Unit, Department of Neurological, Motor and Sensorial Sciences, IRCCS San Raffaele Pisana, Rome, Italy
    Cephalalgia 30:686-9. 2010
    ..Our study excludes a comorbid association between ET and migraine. When ET and migraine coexist their clinical phenotype and evolution remain almost unchanged...
  21. doi request reprint Somatosensory temporal discrimination tested in patients receiving botulinum toxin injection for cervical dystonia
    Alessandra Scontrini
    Department of Neurology and Psychiatry, Sapienza, University of Rome, Rome, Italy
    Mov Disord 26:742-6. 2011
    ..The lack of BTX-induced effects on STD thresholds suggests that STD recruits neural structures uninvolved in muscle spindle afferent activation...
  22. doi request reprint Bladder symptoms assessed with overactive bladder questionnaire in Parkinson's disease
    Elisa Iacovelli
    Department of Neurological Sciences, University of Rome Sapienza, Rome, Italy
    Mov Disord 25:1203-9. 2010
    ..Our study also suggests that the OAB-q is a simple, easily administered test that can objectively evaluate bladder function in patients with PD...
  23. ncbi request reprint Which model of stroke unit is better for stroke patient management?
    Svetlana Lorenzano
    Neurovascular Treatment Unit, Department of Neurological Sciences, University of Rome, La Sapienza, Rome, Italy
    Clin Exp Hypertens 28:377-82. 2006
    ....
  24. ncbi request reprint The tau gene in progressive supranuclear palsy: exclusion of mutations in coding exons and exon 10 splice sites, and identification of a new intronic variant of the disease-associated H1 haplotype in Italian cases
    V Bonifati
    Department of Neurosciences, La Sapienza University, Roma, Italy
    Neurosci Lett 274:61-5. 1999
    ..Although a pathogenic role cannot be entirely excluded, +39deltaG is likely to be a rare polymorphism that may be in linkage disequilibrium with a biologically relevant locus inside or near to the tau gene...
  25. pmc Multidisciplinary approach for diagnosing syncope: a retrospective study on 521 outpatients
    S Strano
    Cardiovascular Pathophysiology, University of Rome La Sapienza, 00161 Rome, Italy
    J Neurol Neurosurg Psychiatry 76:1597-600. 2005
    ..To describe causes of syncope in outpatients in whom structural heart disease was ruled out as a cause, and to analyse the role of a multidisciplinary approach in a syncope unit for the diagnosis of patients with syncope of unknown origin...
  26. doi request reprint A transverse and longitudinal MR imaging voxel-based morphometry study in patients with primary cervical dystonia
    P Pantano
    Department of Neurological Sciences, Sapienza University of Rome, Rome, Italy
    AJNR Am J Neuroradiol 32:81-4. 2011
    ..Our purpose was to evaluate GM volumes in patients with CD at baseline and 5 years later...
  27. doi request reprint Sad and happy facial emotion recognition impairment in progressive supranuclear palsy in comparison with Parkinson's disease
    Francesco E Pontieri
    I R C C S Santa Lucia Foundation, Rome, Italy
    Parkinsonism Relat Disord 18:871-5. 2012
    ....
  28. ncbi request reprint Case-control study of multiple system atrophy
    Nicola Vanacore
    Department of Neurological Sciences, University La Sapienza, Rome, Italy
    Mov Disord 20:158-63. 2005
    ..Our results suggest that occupational history of farming is a risk factor for MSA. Smoking and farming seem to influence MSA risk independently. Further epidemiological studies might provide clues on the etiopathogenesis of MSA...
  29. doi request reprint Cranial movement disorders: clinical features, pathophysiology, differential diagnosis and treatment
    Giovanni Fabbrini
    Movement Disorders Clinic, Department of Neurosciences and Neuromed Institute, Sapienza University of Rome, Rome
    Nat Clin Pract Neurol 5:93-105. 2009
    ..Here, we review the clinical features, pathophysiologies and therapies of the main movement disorders that affect the face, jaw, tongue and palate...
  30. doi request reprint Dopamine transporter immunoreactivity in peripheral blood lymphocytes in multiple system atrophy
    Francesca R Buttarelli
    Department of Neurological Sciences, University Sapienza, Rome, Italy
    J Neural Transm 116:161-5. 2009
    ..The reduction of DAT-IR in PBL in these disorders may represent a compensatory phenomenon aimed at reducing intracellular dopamine influx and, consequently, dopamine-mediated aggravation of oxidative stress in these cells...
  31. doi request reprint Clinical phenomenology of dystonia
    Carlo Colosimo
    Department of Neurology and Psychiatry and Neuromed Institute IRCSS, Sapienza University of Rome, Italy
    Int Rev Neurobiol 98:509-24. 2011
    ..The different subtypes of focal and segmental dystonias may have different clinical features. Neuropsychiatric disorders may be present in dystonia...
  32. doi request reprint Diffusion tensor imaging in patients with primary cervical dystonia and in patients with blepharospasm
    G Fabbrini
    Department of Neurological Sciences and Neuromed Institute IRCCS, La Sapienza University of Rome, Rome, Italy
    Eur J Neurol 15:185-9. 2008
    ..The abnormal DTI findings in patients with CD suggest the presence of brain ultrastructural changes in adult-onset primary CD...
  33. doi request reprint Selective impairment of action-verb naming and comprehension in progressive supranuclear palsy
    Antonio Daniele
    Institute of Neurology, Catholic University, Rome, Italy
    Cortex 49:948-60. 2013
    ....
  34. ncbi request reprint Epidemiology of progressive supranuclear palsy. ESGAP Consortium. European Study Group on Atypical Parkinsonisms
    N Vanacore
    Department of Neurological Sciences, La Sapienza University, Rome, Italy
    Neurol Sci 22:101-3. 2001
    ..The significance of this association is still not clear. We have performed a case-control study on 58 PSP cases, 116 hospital controls and 58 population controls...
  35. ncbi request reprint Cerebrospinal fluid analysis for Whipple's disease in patients with progressive supranuclear palsy
    Francesca Romana Pezzella
    Dipartimento di Scienze Neurologiche, Universita La Sapienza, Rome, Italy
    Mov Disord 19:220-2. 2004
    ..We looked for WD pathogen DNA in the cerebrospinal fluid of 9 patients with a clinical diagnosis of PSP. The analysis was negative for all samples, showing that WD is not commonly involved in the aetiopathogenesis of PSP...
  36. ncbi request reprint Epidemiology of multiple system atrophy. ESGAP Consortium. European Study Group on Atypical Parkinsonisms
    N Vanacore
    Department of Neurological Sciences, La Sapienza University, Rome, Italy
    Neurol Sci 22:97-9. 2001
    ..We have performed a case-control study on 73 MSA cases, 146 hospital controls and 73 population controls...
  37. doi request reprint Craniocervical dystonia: clinical and pathophysiological features
    C Colosimo
    Department of Neurological Sciences, Sapienza University of Rome, Rome, Italy
    Eur J Neurol 17:15-21. 2010
    ..The best treatment for craniocervical dystonia is botulinum toxin injected into the overactive muscles...
  38. ncbi request reprint Fast voluntary neck movements in patients with cervical dystonia: a kinematic study before and after therapy with botulinum toxin type A
    B Gregori
    Department of Neurological Sciences, University of Rome La Sapienza, Viale dell Universita, 30, 00185 Rome, Italy
    Clin Neurophysiol 119:273-80. 2008
    ..To study fast voluntary neck movements in patients with cervical dystonia (CD) before and after therapy with botulinum toxin type-A (BTX-A)...
  39. ncbi request reprint Management of multiple system atrophy: state of the art
    C Colosimo
    Department of Neurological Sciences, La Sapienza University, Rome, Italy
    J Neural Transm 112:1695-704. 2005
    ..The treatment of the very common genitourinary symptoms (incontinence, retention, impotence) should also be considered in order to improve the quality of life of these patients...
  40. ncbi request reprint Donepezil in the treatment of progressive supranuclear palsy
    G Fabbrini
    Department of Neurological Sciences, University La Sapienza, Rome
    Acta Neurol Scand 103:123-5. 2001
    ..To evaluate the effect of 3 month therapy with donepezil, a centrally acting cholinesterase inhibitor, on cognitive performances, motor function and daily living activities in progressive supranuclear palsy (PSP)...
  41. ncbi request reprint Apraxia of eyelid opening in a case of atypical corticobasal degeneration
    M Sepe-Monti
    Dipartimento di Scienze Neurologiche, Universita La Sapienza, Rome, Italy
    J Neural Transm 110:1145-8. 2003
    ..We suggest that the finding of AEO in patients with a frontotemporal syndrome could be a helpful expedient for the early diagnosis of atypical clinical findings of CBD, characterised by behavioural and cognitive aspects at first...
  42. ncbi request reprint Multiple system atrophy
    Gregor K Wenning
    Department of Neurology, University Hospital, A 6020 Innsbruck, Austria
    Lancet Neurol 3:93-103. 2004
    ..Symptomatic therapeutic strategies are still limited; however, several candidate neuroprotective agents have entered phase II and phase III clinical trials...
  43. ncbi request reprint Development and validation of the Unified Multiple System Atrophy Rating Scale (UMSARS)
    Gregor K Wenning
    Department of Neurology, University of Innsbruck, Austria
    Mov Disord 19:1391-402. 2004
    ..Based on our findings, the UMSARS appears to be a multidimensional, reliable, and valid scale for semiquantitative clinical assessments of MSA patients...
  44. ncbi request reprint Accuracy of clinical diagnosis of progressive supranuclear palsy
    Yasushi Osaki
    National Hospital for Neurology and Neurosurgery, London, United Kingdom
    Mov Disord 19:181-9. 2004
    ....
  45. ncbi request reprint Health-related quality of life in multiple system atrophy
    Anette Schrag
    Department of Clinical Neurosciences, Royal Free and University College Medical School, London, United Kingdom
    Mov Disord 21:809-15. 2006
    ....
  46. doi request reprint The PRIAMO study: background, methods and recruitment
    Angelo Antonini
    Parkinson Institute, Milan, Italy
    Neurol Sci 29:61-5. 2008
    ..PRIAMO has analysed a total of 1307 patients (out of 1325 initially enrolled). We expect that PRIAMO will substantially help to quantify the burden of NMS in patients with parkinsonism...
  47. doi request reprint Red flags for multiple system atrophy
    Martin Köllensperger
    Section for Clinical Neurobiology, Department of Neurology, Innsbruck Medical University, Austria
    Mov Disord 23:1093-9. 2008
    ..9 (+/-7.0) months earlier than with the Consensus criteria alone. We propose a combination of two out of six red flag categories as additional diagnostic criteria for probable MSA-P...
  48. ncbi request reprint Reply: Lack of association between progressive supranuclear palsy and arterial hypertension: a clinicopathological study
    Carlo Colosimo
    Mov Disord 20:1086-7. 2005