Rolando Cimaz

Summary

Affiliation: University of Milan
Country: Italy

Publications

  1. ncbi request reprint Osteoporosis
    R Cimaz
    Department of Pediatrics, ICP, Clinica Pediatrica, Via Commenda 9, 20122 Milano, Italy
    Curr Rheumatol Rep 3:365-70. 2001
  2. ncbi request reprint Sarcoidosis in the pediatric age
    R Cimaz
    Clinica Pediatrica, Milan, Italy
    Clin Exp Rheumatol 20:231-7. 2002
  3. ncbi request reprint Osteogenesis imperfecta: new treatment options
    Guillaume Chevrel
    Department of Pediatrics, Edouard Herrriot Hospital, 5, Place d Arsonval, 69437 Lyon Cedex 03, France
    Curr Rheumatol Rep 8:474-9. 2006
  4. ncbi request reprint Primary Sjögren syndrome in the paediatric age: a multicentre survey
    Rolando Cimaz
    Clinica Pediatrica, Istituti Clinici di Perfezionamento, Via Commenda 9, 20122 Milano, Italy
    Eur J Pediatr 162:661-5. 2003
  5. ncbi request reprint Incidence and spectrum of neonatal lupus erythematosus: a prospective study of infants born to mothers with anti-Ro autoantibodies
    Rolando Cimaz
    Pediatric Department, ICP, Milano, Italy
    J Pediatr 142:678-83. 2003
  6. ncbi request reprint Alterations in the immune system of children from mothers treated with immunosuppressive agents during pregnancy
    R Cimaz
    Clinica Pediatrica, ICP, Via Commenda 9, Milan 20122, Italy
    Toxicol Lett 149:155-62. 2004
  7. ncbi request reprint Any increased risk of autoimmune disease?
    R Cimaz
    Department of Pediatrics, Istituti Clinici di Perfezionamento, Milano, Italy
    Lupus 13:736-9. 2004
  8. ncbi request reprint Changes in markers of bone turnover and inflammatory variables during alendronate therapy in pediatric patients with rheumatic diseases
    Rolando Cimaz
    Clinica Pediatrica, ICP, Milano, Italy
    J Rheumatol 29:1786-92. 2002
  9. ncbi request reprint Ultraviolet light exposure is not a requirement for the development of cutaneous neonatal lupus
    R Cimaz
    Department of Pediatrics, ICP, Milan, Italy
    Lupus 11:257-60. 2002
  10. ncbi request reprint Prevalence of anti-cardiolipin, anti-beta2 glycoprotein I, and anti-prothrombin antibodies in young patients with epilepsy
    R Cimaz
    Department of Pediatrics, ICP, Milano, Italy
    Epilepsia 43:52-9. 2002

Collaborators

Detail Information

Publications53

  1. ncbi request reprint Osteoporosis
    R Cimaz
    Department of Pediatrics, ICP, Clinica Pediatrica, Via Commenda 9, 20122 Milano, Italy
    Curr Rheumatol Rep 3:365-70. 2001
    ..New treatment options are available; among these, the use of bisphosphonates seems to be the more promising approach...
  2. ncbi request reprint Sarcoidosis in the pediatric age
    R Cimaz
    Clinica Pediatrica, Milan, Italy
    Clin Exp Rheumatol 20:231-7. 2002
  3. ncbi request reprint Osteogenesis imperfecta: new treatment options
    Guillaume Chevrel
    Department of Pediatrics, Edouard Herrriot Hospital, 5, Place d Arsonval, 69437 Lyon Cedex 03, France
    Curr Rheumatol Rep 8:474-9. 2006
    ..A new approach has been developed to replace mutated genes using mesenchymal stem cells and a construct, which inactivates COL1A1...
  4. ncbi request reprint Primary Sjögren syndrome in the paediatric age: a multicentre survey
    Rolando Cimaz
    Clinica Pediatrica, Istituti Clinici di Perfezionamento, Via Commenda 9, 20122 Milano, Italy
    Eur J Pediatr 162:661-5. 2003
    ..Follow-up varied from 0 to 7.5 years from onset, without major complications in the majority of patients...
  5. ncbi request reprint Incidence and spectrum of neonatal lupus erythematosus: a prospective study of infants born to mothers with anti-Ro autoantibodies
    Rolando Cimaz
    Pediatric Department, ICP, Milano, Italy
    J Pediatr 142:678-83. 2003
    ..We carried out a prospective study to determine the incidence of individual NLE features...
  6. ncbi request reprint Alterations in the immune system of children from mothers treated with immunosuppressive agents during pregnancy
    R Cimaz
    Clinica Pediatrica, ICP, Via Commenda 9, Milan 20122, Italy
    Toxicol Lett 149:155-62. 2004
    ..Although our results are preliminary, we conclude that prenatal exposure to immunosuppressive drugs does not have a profound effect to the developing immune system. More data and a longer follow-up are needed to confirm these results...
  7. ncbi request reprint Any increased risk of autoimmune disease?
    R Cimaz
    Department of Pediatrics, Istituti Clinici di Perfezionamento, Milano, Italy
    Lupus 13:736-9. 2004
    ..Babies with neonatal lupus are not at increased risk to develop SLE in later life, but a continued follow-up is suggested, especially prior to adolescence and if the mother herself has an autoimmune disease...
  8. ncbi request reprint Changes in markers of bone turnover and inflammatory variables during alendronate therapy in pediatric patients with rheumatic diseases
    Rolando Cimaz
    Clinica Pediatrica, ICP, Milano, Italy
    J Rheumatol 29:1786-92. 2002
    ..In this study, we evaluated the changes in bone metabolism and disease activity markers in 45 patients ages 5 to 18 years (31 female, 14 male) with rheumatic diseases treated with alendronate for 12 months...
  9. ncbi request reprint Ultraviolet light exposure is not a requirement for the development of cutaneous neonatal lupus
    R Cimaz
    Department of Pediatrics, ICP, Milan, Italy
    Lupus 11:257-60. 2002
    ..This latter finding argues against sun exposure being necessary for lesion induction...
  10. ncbi request reprint Prevalence of anti-cardiolipin, anti-beta2 glycoprotein I, and anti-prothrombin antibodies in young patients with epilepsy
    R Cimaz
    Department of Pediatrics, ICP, Milano, Italy
    Epilepsia 43:52-9. 2002
    ....
  11. ncbi request reprint [Corticotherapy and bisphosphonates]
    R Cimaz
    Clinica Pediatrica, Istituti Clinici di Perfezionamento, Via Commenda 9, 20122 Milano, Italie
    Arch Pediatr 12:686-7. 2005
  12. ncbi request reprint [Kawasaki disease: an infectious disease?]
    R Cimaz
    Département de rhumatologie pédiatrique, Université de Milan, Italy
    Rev Med Interne 26:15-8. 2005
  13. ncbi request reprint Safety and immunogenicity of a conjugate vaccine against Haemophilus influenzae type b in splenectomized and nonsplenectomized patients with Cooley anemia
    R Cimaz
    Clinica Pediatrica De Marchi, Istituti Clinici di Perfezionamento, 20122 Milan, Italy
    J Infect Dis 183:1819-21. 2001
    ..Hib conjugate vaccine is safe and immunogenic in patients with thalassemia major; however, additional studies are needed to assess the need and timing of booster vaccination to maintain long-term immunity...
  14. ncbi request reprint An update on Kawasaki disease
    Rolando Cimaz
    Department of Pediatrics, ICP, Milano, Italy
    Autoimmun Rev 2:258-63. 2003
    ..Prompt diagnosis is critical, since the early administration of intravenous immunoglobulins and aspirin reduces the rate of coronary abnormalities to less than 5% of patients...
  15. ncbi request reprint Transforming growth factor beta1 in the pathogenesis of autoimmune congenital complete heart block: lesson from twins and triplets discordant for the disease
    Rolando Cimaz
    Clinica Pediatrica, Fondazione Policlinico Mangiagalli, Via Commenda 9, 20122 Milan, Italy
    Arthritis Rheum 54:356-9. 2006
    ..The aim of our study was to investigate polymorphisms of transforming growth factor beta1 (TGFbeta1) and tumor necrosis factor alpha (TNFalpha) genes in twins and triplets discordant for CCHB whose mothers are anti-Ro/La positive...
  16. ncbi request reprint [Arthritis and infections]
    R Cimaz
    Clinica Pediatrica De Marchi, ICP, Milan
    Minerva Pediatr 57:181-8. 2005
    ....
  17. ncbi request reprint [Diagnosis and treatment of juvenile osteoporosis]
    R Cimaz
    Clinica Pediatrica, Istituti Clinici di Perfezionamento, Via Commenda 9, 20122 Milano, Italy
    Arch Pediatr 12:585-93. 2005
    ..New treatments such as bisphosphonates and calcitonin are now available, although their use in the paediatric age has been limited...
  18. ncbi request reprint Bone status evaluation with calcaneal ultrasound in children with chronic rheumatic diseases. A one year followup study
    Fernanda Falcini
    Department of Pediatrics, Rheumatology Unit, University of Florence, Italy
    J Rheumatol 30:179-84. 2003
    ..To evaluate at baseline and after one year the bone status in children with chronic rheumatic diseases (CRD) using quantitative ultrasound techniques...
  19. ncbi request reprint Immune function in children born to mothers with autoimmune diseases and exposed in utero to immunosuppressants
    M Biggioggero
    Department of Internal Medicine, University of Milan, IRCCS Istituto Auxologico Italiano, Milan, Italy
    Lupus 16:651-6. 2007
    ..Immunosuppressive regimens currently in use for controlling maternal autoimmune disorders do not significantly affect the immune status of the offspring...
  20. ncbi request reprint Osteoporosis in childhood rheumatic diseases: prevention and therapy
    Rolando Cimaz
    Department of Paediatrics, ICP, Milano, Italy
    Best Pract Res Clin Rheumatol 16:397-409. 2002
    ..New treatments such as bisphosphonates and calcitonin are now available, although their use for paediatric patients has been limited...
  21. ncbi request reprint Lack of association between the HLA-DRB1 locus and post-streptococcal reactive arthritis and acute rheumatic fever in Italian children
    Gabriele Simonini
    Rheumatology Unit, Department of Pediatrics, University of Florence, 50132 Firenze, Italy
    Semin Arthritis Rheum 34:553-8. 2004
    ..Possible associations with HLA class II antigens of PSReA (DRB1*01) and ARF (DRB1*16) were described previously in white Americans. To confirm these findings, we studied DRB1 alleles in a group of Italian children with PSReA and ARF...
  22. ncbi request reprint Concomitant disappearance of electrocardiographic abnormalities and of acquired maternal autoantibodies during the first year of life in infants who had QT interval prolongation and anti-SSA/Ro positivity without congenital heart block at birth
    Rolando Cimaz
    Istituti Clinici di Perfezionamento, Milan, Italy
    Arthritis Rheum 48:266-8. 2003
  23. ncbi request reprint Reflex sympathetic dystrophy in children
    R Cimaz
    Pediatric Department, University of Milan, Italy
    J Child Neurol 14:363-7. 1999
    ..We also point out that the diagnosis is mainly clinical. An early diagnosis can avoid unnecessary tests and potentially can improve response to treatment, and prognosis...
  24. doi request reprint Safety and efficacy of infliximab and adalimumab for refractory uveitis in juvenile idiopathic arthritis: 1-year followup data from the Italian Registry
    Maria E Zannin
    Department of Pediatrics, University of Padua, Padua, Italy
    J Rheumatol 40:74-9. 2013
    ..To evaluate safety and efficacy of adalimumab (ADA) and infliximab (IFX) for the treatment of juvenile idiopathic arthritis-related anterior uveitis (JIA-AU)...
  25. ncbi request reprint In vivo effects of maternal immunosuppression during pregnancy on the immune function of newborn infants
    Elisa Meregalli
    Pediatrics, ICP, Milan, Italy
    Arh Hig Rada Toksikol 56:151-6. 2005
    ....
  26. ncbi request reprint Association of low bone mass with vitamin d receptor gene and calcitonin receptor gene polymorphisms in juvenile idiopathic arthritis
    Laura Masi
    Department of Pediatrics, University of Florence, Florence, Italy
    J Rheumatol 29:2225-31. 2002
    ..To compare bone density with polymorphisms in the calcitonin receptor (CTR) and vitamin D receptor (VDR) genes in 50 patients with juvenile idiopathic arthritis and 80 matched controls...
  27. doi request reprint Timing of uveitis onset in oligoarticular juvenile idiopathic arthritis (JIA) is the main predictor of severe course uveitis
    Maria E Zannin
    Department of Pediatrics, University of Padova, Padova, Italy
    Acta Ophthalmol 90:91-5. 2012
    ..Aim of the present study was to validate a statistical model to predict a severe course of anterior uveitis (AU) in patients with juvenile idiopathic arthritis (JIA)...
  28. ncbi request reprint Remission in juvenile chronic arthritis: a cohort study of 683 consecutive cases with a mean 10 year followup
    Flavio Fantini
    Institute of Rheumatology, Milano, Italy
    J Rheumatol 30:579-84. 2003
    ..As continuity of care in our institution allows longterm followup studies, we reviewed the files of all consecutive patients with juvenile chronic (idiopathic) arthritis (JCA) followed since 1970 to establish the frequency of remission...
  29. ncbi request reprint Neonatal lupus
    Antonio Brucato
    Divisione Medica Brera and Rheumatology, Ospedale Niguarda, Milan, Italy
    Clin Rev Allergy Immunol 23:279-99. 2002
    ..Serial echocardiograms and obstetric sonograms, performed at least every 2 wk starting from the 16 wk gestation, are recommended in anti-Ro/SSA positive pregnant women...
  30. ncbi request reprint Neprilysin levels in plasma and synovial fluid of juvenile idiopathic arthritis patients
    Gabriele Simonini
    Rheumatology Unit, Department of Pediatrics, University of Florence, Via Pico della Mirandola 24, 50132 Florence, Italy
    Rheumatol Int 25:336-40. 2005
    ..In 20 subjects requiring local steroid injection, NEP was measured in synovial fluid...
  31. doi request reprint Clinical features and outcome of Cogan syndrome
    Ilaria Pagnini
    Department of Pediatrics, University of Florence, Florence, Italy
    J Pediatr 160:303-307.e1. 2012
    ..To review the clinical features of Cogan syndrome, a rare vasculitis characterized by systemic, ocular, and audiovestibular symptoms...
  32. pmc Normal neuropsychological development in children with congenital complete heart block who may or may not be exposed to high-dose dexamethasone in utero
    A Brucato
    Department of Internal Medicine and Rheumatology, Niguarda Hospital, Milano, Italy
    Ann Rheum Dis 65:1422-6. 2006
    ..Maternal anti-Ro/Sjögren's syndrome A (SSA) antibodies may also be associated with learning disabilities in offspring...
  33. ncbi request reprint Risk of congenital complete heart block in newborns of mothers with anti-Ro/SSA antibodies detected by counterimmunoelectrophoresis: a prospective study of 100 women
    A Brucato
    Niguarda Hospital, Milan, Italy
    Arthritis Rheum 44:1832-5. 2001
    ..Additional electrocardiographic abnormalities such as sinus bradycardia and prolongation of the QT interval may be present in their children...
  34. ncbi request reprint A fatal case of systemic lupus erythematosus complicated by acute pancreatitis, invasive aspergillosis and features of thrombotic thrombocytopenic purpura
    F Fantini
    Department of Rheumatology, University of Milan, Gaetano Pini Institute, Milano, Italy
    Lupus 12:418-21. 2003
    ..The relationship between the three entities is complex, and it is difficult to establish which of the different events took place first and triggered the others...
  35. ncbi request reprint Neonatal lupus: fetal myocarditis progressing to atrioventricular block in triplets
    V Fesslova
    Department of Cardiology, Istituti Clinici di Perfezionamento, Milan, Italy
    Lupus 12:775-8. 2003
    ..Twin III developed a first-degree AV block that switched to a periodic second-degree block later, while twin II displayed only liver enzyme abnormalities...
  36. ncbi request reprint Bone mass change during methotrexate treatment in patients with juvenile rheumatoid arthritis
    M L Bianchi
    Centro Metabolismo Minerale e Osseo, Divisione Endocrinologia, Istituto Auxologico Italiano IRCCS, Milan, Italy
    Osteoporos Int 10:20-5. 1999
    ..Pubertal stage and disease activity significantly influenced the yearly change in BMD. In conclusion, our data suggest that long-term, low-dose therapy with MTX does not induce osteopenia in children with JRA...
  37. ncbi request reprint A comparison of response criteria to evaluate therapeutic response in patients with juvenile idiopathic arthritis treated with methotrexate and/or anti-tumor necrosis factor alpha agents
    A Lurati
    Gaetano Pini Institute, Milan, Italy
    Arthritis Rheum 54:1602-7. 2006
    ....
  38. ncbi request reprint Evidence for immune activation against oxidized lipoproteins in inactive phases of juvenile chronic arthritis
    G Simonini
    Department of Pediatrics, University of Florence, Italy
    J Rheumatol 28:198-203. 2001
    ....
  39. ncbi request reprint Efficacy and safety profile of cyclosporin A in the treatment of juvenile chronic (idiopathic) arthritis. Results of a 10-year prospective study
    V Gerloni
    Rheumatology Department, University of Milan, Centre for Rheumatic Children, Gaetano Pini Institute, Milan, Italy
    Rheumatology (Oxford) 40:907-13. 2001
    ..Eight systemic patients withdrew from therapy owing to complete remission. CONCLUSION: Cyclosporin can be used in the treatment of JCA, its main benefits being the control of fever and a steroid-sparing effect...
  40. ncbi request reprint Gender and ethnic origin have no effect on longterm outcome of childhood-onset systemic lupus erythematosus
    Paivi M Miettunen
    Division of Rheumatology, Department of Pediatrics, University of Calgary, Calgary, AB, Canada
    J Rheumatol 31:1650-4. 2004
    ..To investigate the associations of gender and ethnic origin with longterm outcome in childhood-onset systemic lupus erythematosus (SLE)...
  41. ncbi request reprint Electroretinograms of children born to mothers treated with hydroxychloroquine during pregnancy and breast-feeding: comment on the article by Costedoat-Chalumeau et al
    Rolando Cimaz
    Arthritis Rheum 50:3056-7; author reply 3057-8. 2004
  42. ncbi request reprint Osteoprotegerin serum levels in Kawasaki disease: an additional potential marker in predicting children with coronary artery involvement
    Gabriele Simonini
    Department of Paediatrics, Rheumatology Unit, University of Florence, Florence, Italy
    J Rheumatol 32:2233-8. 2005
    ..We evaluated serum levels of OPG in a group of children with Kawasaki disease (KD), before immunoglobulin (IVIG) infusion and at 3-month followup...
  43. ncbi request reprint [Kawasaki disease]
    Rolando Cimaz
    Hospices Civils de Lyon, Universite Claude Bernard, Lyon 1, 69437 Lyon Cedex
    Rev Prat 57:1985-8. 2007
    ..Prompt diagnosis is critical, since the early administration of intravenous immunoglobulins and aspirin reduces the rate of coronary abnormalities to less than 5% of patients...
  44. ncbi request reprint Usefulness of bone ultrasound techniques in pediatric rheumatic diseases
    Gabriele Simonini
    J Rheumatol 32:198-9; author reply 199. 2005
  45. ncbi request reprint Osteoprotegerin (OPG)/RANK-L system in juvenile idiopathic arthritis: is there a potential modulating role for OPG/RANK-L in bone injury?
    Laura Masi
    Department of Internal Medicine, University of Florence, Florence, Italy
    J Rheumatol 31:986-91. 2004
    ....
  46. ncbi request reprint Neonatal lupus manifests as isolated neutropenia and mildly abnormal liver functions
    Sivalingam Kanagasegar
    Arthritis and Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, 73104, USA
    J Rheumatol 29:187-91. 2002
    ..Furthermore, although other factors may contribute, these data suggest that anti-60 kDa Ro is directly involved in the pathogenesis of neutropenia...
  47. doi request reprint Dual-energy X-ray aborptiometry assessment in children and adolescents with diseases that may affect the skeleton: the 2007 ISCD Pediatric Official Positions
    Nick Bishop
    Sheffield University, Sheffield Childrens NHS Foundation Trust, Western Bank, Sheffield, UK
    J Clin Densitom 11:29-42. 2008
    ..Importantly, this document also highlights significant gaps in our knowledge, emphasizing areas for future research...
  48. ncbi request reprint Pediatric antiphospholipid syndrome
    Rolando Cimaz
    Departement de Pediatrie, Pavillon S, Hopital Edouard Herriot, 69437, Lyon, France
    Rheum Dis Clin North Am 32:553-73. 2006
    ..Studies on the outcome of pediatric APS and the relative risks of prolonged anticoagulation in children are necessary to determine the type and duration of anticoagulation therapy...
  49. pmc Anti-inflammatory and immunosuppressive drugs and reproduction
    Monika Østensen
    Department of Rheumatology and Clinical Immunology Allergology, University Hospital of Bern, Switzerland
    Arthritis Res Ther 8:209. 2006
    ..Recommendations for drug treatment during pregnancy and lactation are given...
  50. ncbi request reprint Localized scleroderma in childhood is not just a skin disease
    Francesco Zulian
    Dipartimento di Pediatria, Universita di Padova, Padua, Italy
    Arthritis Rheum 52:2873-81. 2005
    ..We studied the prevalence and clinical features of extracutaneous manifestations in a large cohort of children with juvenile localized scleroderma...
  51. ncbi request reprint The Pediatric Rheumatology International Trials Organization criteria for the evaluation of response to therapy in juvenile systemic lupus erythematosus: prospective validation of the disease activity core set
    Nicolino Ruperto
    Pediatric Rheumatology International Trials Organization PRINTO, IRCCS G Gaslini, Universita di Genova, Pediatria II Reumatologia, Largo Gaslini, Genoa, Italy
    Arthritis Rheum 52:2854-64. 2005
    ..To validate and promulgate a core set of outcome measures for the evaluation of response to treatment in patients with juvenile systemic lupus erythematosus (SLE)...
  52. ncbi request reprint Pregnancy and autoimmunity: maternal treatment and maternal disease influence on pregnancy outcome
    Angela Tincani
    Spedali Civili e Universita di Brescia, Brescia, Italy
    Autoimmun Rev 4:423-8. 2005
    ..However, information about long-term outcome of children exposed to immunosuppressive drugs "in utero" are still lacking and more efforts are needed in this research area...
  53. ncbi request reprint A girl with a sore ear
    Fernanda Falcini
    Department of Paediatrics Rheumatology Unit, 50132 Florence, Italy
    Lancet 362:1894. 2003