Research Topics
Species | Rolando CimazSummaryAffiliation: University of Milan Country: Italy Publications
| Collaborators
|
Detail Information
Publications
Osteogenesis imperfecta: new treatment optionsGuillaume Chevrel
Department of Pediatrics, Edouard Herrriot Hospital, 5, place d'Arsonval, 69437 Lyon Cedex 03, France
Curr Rheumatol Rep 8:474-9. 2006..A new approach has been developed to replace mutated genes using mesenchymal stem cells and a construct, which inactivates COL1A1...- OsteoporosisR Cimaz
Department of Pediatrics, ICP, Clinica Pediatrica, Via Commenda 9, 20122 Milano, Italy
Curr Rheumatol Rep 3:365-70. 2001..New treatment options are available; among these, the use of bisphosphonates seems to be the more promising approach... - Primary Sjögren syndrome in the paediatric age: a multicentre surveyRolando Cimaz
Clinica Pediatrica, Istituti Clinici di Perfezionamento, Via Commenda 9, 20122 Milano, Italy
Eur J Pediatr 162:661-5. 2003..CONCLUSION: recurrent parotid swelling is a common feature of primary Sjögren syndrome in childhood and often occurs as a presenting feature. Sicca symptoms may be rarer... - Incidence and spectrum of neonatal lupus erythematosus: a prospective study of infants born to mothers with anti-Ro autoantibodiesRolando Cimaz
Pediatric Department, ICP, Milano, Italy
J Pediatr 142:678-83. 2003..We carried out a prospective study to determine the incidence of individual NLE features... - Alterations in the immune system of children from mothers treated with immunosuppressive agents during pregnancyR Cimaz
Clinica Pediatrica, ICP, Via Commenda 9, Milan 20122, Italy
Toxicol Lett 149:155-62. 2004..Although our results are preliminary, we conclude that prenatal exposure to immunosuppressive drugs does not have a profound effect to the developing immune system. More data and a longer follow-up are needed to confirm these results... - Any increased risk of autoimmune disease?R Cimaz
Department of Pediatrics, Istituti Clinici di Perfezionamento, Milano, Italy
Lupus 13:736-9. 2004..Babies with neonatal lupus are not at increased risk to develop SLE in later life, but a continued follow-up is suggested, especially prior to adolescence and if the mother herself has an autoimmune disease... - Changes in markers of bone turnover and inflammatory variables during alendronate therapy in pediatric patients with rheumatic diseasesRolando Cimaz
Clinica Pediatrica, ICP, Milano, Italy
J Rheumatol 29:1786-92. 2002..In this study, we evaluated the changes in bone metabolism and disease activity markers in 45 patients ages 5 to 18 years (31 female, 14 male) with rheumatic diseases treated with alendronate for 12 months... - Sarcoidosis in the pediatric ageR Cimaz
Clinica Pediatrica, Milan, Italy
Clin Exp Rheumatol 20:231-7. 2002 - Ultraviolet light exposure is not a requirement for the development of cutaneous neonatal lupusR Cimaz
Department of Pediatrics, ICP, Milan, Italy
Lupus 11:257-60. 2002..This latter finding argues against sun exposure being necessary for lesion induction... - Prevalence of anti-cardiolipin, anti-beta2 glycoprotein I, and anti-prothrombin antibodies in young patients with epilepsyR Cimaz
Department of Pediatrics, ICP, Milano, Italy
Epilepsia 43:52-9. 2002.... - [Corticotherapy and bisphosphonates]R Cimaz
Clinica Pediatrica, Istituti Clinici di Perfezionamento, Via Commenda 9, 20122 Milano, Italie
Arch Pediatr 12:686-7. 2005 - [Kawasaki disease: an infectious disease?]R Cimaz
, , Italy
Rev Med Interne 26:15-8. 2005 - Safety and immunogenicity of a conjugate vaccine against Haemophilus influenzae type b in splenectomized and nonsplenectomized patients with Cooley anemiaR Cimaz
Clinica Pediatrica De Marchi, Istituti Clinici di Perfezionamento, 20122 Milan, Italy
J Infect Dis 183:1819-21. 2001..Hib conjugate vaccine is safe and immunogenic in patients with thalassemia major; however, additional studies are needed to assess the need and timing of booster vaccination to maintain long-term immunity... - An update on Kawasaki diseaseRolando Cimaz
Department of Pediatrics, ICP, Milano, Italy
Autoimmun Rev 2:258-63. 2003..Prompt diagnosis is critical, since the early administration of intravenous immunoglobulins and aspirin reduces the rate of coronary abnormalities to less than 5% of patients... - Transforming growth factor beta1 in the pathogenesis of autoimmune congenital complete heart block: lesson from twins and triplets discordant for the diseaseRolando Cimaz
Clinica Pediatrica, Fondazione Policlinico Mangiagalli, Via Commenda 9, 20122 Milan, Italy
Arthritis Rheum 54:356-9. 2006..The aim of our study was to investigate polymorphisms of transforming growth factor beta1 (TGFbeta1) and tumor necrosis factor alpha (TNFalpha) genes in twins and triplets discordant for CCHB whose mothers are anti-Ro/La positive... - [Arthritis and infections]R Cimaz
Clinica Pediatrica De Marchi, ICP, Milan
Minerva Pediatr 57:181-8. 2005.... - [Diagnosis and treatment of juvenile osteoporosis]R Cimaz
Clinica Pediatrica, Istituti Clinici di Perfezionamento, Via Commenda 9, 20122 Milano, Italy
Arch Pediatr 12:585-93. 2005..New treatments such as bisphosphonates and calcitonin are now available, although their use in the paediatric age has been limited... - Bone status evaluation with calcaneal ultrasound in children with chronic rheumatic diseases. A one year followup studyFernanda Falcini
Department of Pediatrics, Rheumatology Unit, University of Florence, Italy
J Rheumatol 30:179-84. 2003..To evaluate at baseline and after one year the bone status in children with chronic rheumatic diseases (CRD) using quantitative ultrasound techniques... - Immune function in children born to mothers with autoimmune diseases and exposed in utero to immunosuppressantsM Biggioggero
Department of Internal Medicine, University of Milan, IRCCS Istituto Auxologico Italiano, Milan, Italy
Lupus 16:651-6. 2007..Immunosuppressive regimens currently in use for controlling maternal autoimmune disorders do not significantly affect the immune status of the offspring... - Osteoporosis in childhood rheumatic diseases: prevention and therapyRolando Cimaz
Department of Paediatrics, ICP, Milano, Italy
Best Pract Res Clin Rheumatol 16:397-409. 2002..New treatments such as bisphosphonates and calcitonin are now available, although their use for paediatric patients has been limited... - Lack of association between the HLA-DRB1 locus and post-streptococcal reactive arthritis and acute rheumatic fever in Italian childrenGabriele Simonini
Rheumatology Unit, Department of Pediatrics, University of Florence, 50132 Firenze, Italy
Semin Arthritis Rheum 34:553-8. 2004..Possible associations with HLA class II antigens of PSReA (DRB1*01) and ARF (DRB1*16) were described previously in white Americans. To confirm these findings, we studied DRB1 alleles in a group of Italian children with PSReA and ARF... - Concomitant disappearance of electrocardiographic abnormalities and of acquired maternal autoantibodies during the first year of life in infants who had QT interval prolongation and anti-SSA/Ro positivity without congenital heart block at birthRolando Cimaz
Istituti Clinici di Perfezionamento, Milan, Italy
Arthritis Rheum 48:266-8. 2003 - Reflex sympathetic dystrophy in childrenR Cimaz
Pediatric Department, University of Milan, Italy
J Child Neurol 14:363-7. 1999..We also point out that the diagnosis is mainly clinical. An early diagnosis can avoid unnecessary tests and potentially can improve response to treatment, and prognosis... - In vivo effects of maternal immunosuppression during pregnancy on the immune function of newborn infantsElisa Meregalli
Pediatrics, ICP, Milan, Italy
Arh Hig Rada Toksikol 56:151-6. 2005.... - Association of low bone mass with vitamin d receptor gene and calcitonin receptor gene polymorphisms in juvenile idiopathic arthritisLaura Masi
Department of Pediatrics, University of Florence, Florence, Italy
J Rheumatol 29:2225-31. 2002..To compare bone density with polymorphisms in the calcitonin receptor (CTR) and vitamin D receptor (VDR) genes in 50 patients with juvenile idiopathic arthritis and 80 matched controls... - Timing of uveitis onset in oligoarticular juvenile idiopathic arthritis (JIA) is the main predictor of severe course uveitisMaria E Zannin
Department of Pediatrics, University of Padova, Padova, Italy
Acta Ophthalmol 90:91-5. 2012..Aim of the present study was to validate a statistical model to predict a severe course of anterior uveitis (AU) in patients with juvenile idiopathic arthritis (JIA)... - Neprilysin levels in plasma and synovial fluid of juvenile idiopathic arthritis patientsGabriele Simonini
Rheumatology Unit, Department of Pediatrics, University of Florence, Via Pico della Mirandola 24, 50132 Florence, Italy
Rheumatol Int 25:336-40. 2005..In 20 subjects requiring local steroid injection, NEP was measured in synovial fluid... - Remission in juvenile chronic arthritis: a cohort study of 683 consecutive cases with a mean 10 year followupFlavio Fantini
Institute of Rheumatology, Milano, Italy
J Rheumatol 30:579-84. 2003..CONCLUSION: Childhood arthritis achieved remission in only about one-third of our cases, with differences among disease categories based on the diagnosis... - Neonatal lupusAntonio Brucato
Divisione Medica Brera and Rheumatology, Ospedale Niguarda, Milan, Italy
Clin Rev Allergy Immunol 23:279-99. 2002..Serial echocardiograms and obstetric sonograms, performed at least every 2 wk starting from the 16 wk gestation, are recommended in anti-Ro/SSA positive pregnant women... - Clinical features and outcome of Cogan syndromeIlaria Pagnini
Department of Pediatrics, University of Florence, Florence, Italy
J Pediatr 160:303-307.e1. 2012..To review the clinical features of Cogan syndrome, a rare vasculitis characterized by systemic, ocular, and audiovestibular symptoms... - Risk of congenital complete heart block in newborns of mothers with anti-Ro/SSA antibodies detected by counterimmunoelectrophoresis: a prospective study of 100 womenA Brucato
Niguarda Hospital, Milan, Italy
Arthritis Rheum 44:1832-5. 2001..Additional electrocardiographic abnormalities such as sinus bradycardia and prolongation of the QT interval may be present in their children... - Normal neuropsychological development in children with congenital complete heart block who may or may not be exposed to high-dose dexamethasone in uteroA Brucato
Department of Internal Medicine and Rheumatology, Niguarda Hospital, Milano, Italy
Ann Rheum Dis 65:1422-6. 2006..Maternal anti-Ro/Sjögren's syndrome A (SSA) antibodies may also be associated with learning disabilities in offspring... - Neonatal lupus: fetal myocarditis progressing to atrioventricular block in tripletsV Fesslova
Department of Cardiology, Istituti Clinici di Perfezionamento, Milan, Italy
Lupus 12:775-8. 2003..Twin III developed a first-degree AV block that switched to a periodic second-degree block later, while twin II displayed only liver enzyme abnormalities... - A fatal case of systemic lupus erythematosus complicated by acute pancreatitis, invasive aspergillosis and features of thrombotic thrombocytopenic purpuraF Fantini
Department of Rheumatology, University of Milan, Gaetano Pini Institute, Milano, Italy
Lupus 12:418-21. 2003..The relationship between the three entities is complex, and it is difficult to establish which of the different events took place first and triggered the others... - A comparison of response criteria to evaluate therapeutic response in patients with juvenile idiopathic arthritis treated with methotrexate and/or anti-tumor necrosis factor alpha agentsA Lurati
Gaetano Pini Institute, Milan, Italy
Arthritis Rheum 54:1602-7. 2006.... - Evidence for immune activation against oxidized lipoproteins in inactive phases of juvenile chronic arthritisG Simonini
Department of Pediatrics, University of Florence, Italy
J Rheumatol 28:198-203. 2001.... - Bone mass change during methotrexate treatment in patients with juvenile rheumatoid arthritisM L Bianchi
Centro Metabolismo Minerale e Osseo, Divisione Endocrinologia, Istituto Auxologico Italiano IRCCS, Milan, Italy
Osteoporos Int 10:20-5. 1999..Pubertal stage and disease activity significantly influenced the yearly change in BMD. In conclusion, our data suggest that long-term, low-dose therapy with MTX does not induce osteopenia in children with JRA... - Efficacy and safety profile of cyclosporin A in the treatment of juvenile chronic (idiopathic) arthritis. Results of a 10-year prospective studyV Gerloni
Rheumatology Department, University of Milan, Centre for Rheumatic Children, Gaetano Pini Institute, Milan, Italy
Rheumatology (Oxford) 40:907-13. 2001..Eight systemic patients withdrew from therapy owing to complete remission. CONCLUSION: Cyclosporin can be used in the treatment of JCA, its main benefits being the control of fever and a steroid-sparing effect... - Osteoprotegerin (OPG)/RANK-L system in juvenile idiopathic arthritis: is there a potential modulating role for OPG/RANK-L in bone injury?Laura Masi
Department of Internal Medicine, University of Florence, Florence, Italy
J Rheumatol 31:986-91. 2004.... - Gender and ethnic origin have no effect on longterm outcome of childhood-onset systemic lupus erythematosusPaivi M Miettunen
Division of Rheumatology, Department of Pediatrics, University of Calgary, Calgary, AB, Canada
J Rheumatol 31:1650-4. 2004..CONCLUSION: The median SDI score was high for this cohort with childhood-onset SLE. In contrast to other published data, no association of male gender and/or non-Caucasian ethnicity with poor outcome was found in our study cohort... - Electroretinograms of children born to mothers treated with hydroxychloroquine during pregnancy and breast-feeding: comment on the article by Costedoat-Chalumeau et alRolando Cimaz
Arthritis Rheum 50:3056-7; author reply 3057-8. 2004 - [Kawasaki disease]Rolando Cimaz
Hospices Civils de Lyon, Universite Claude Bernard, Lyon 1, 69437 Lyon Cedex
Rev Prat 57:1985-8. 2007..Prompt diagnosis is critical, since the early administration of intravenous immunoglobulins and aspirin reduces the rate of coronary abnormalities to less than 5% of patients... - Usefulness of bone ultrasound techniques in pediatric rheumatic diseasesGabriele Simonini
J Rheumatol 32:198-9; author reply 199. 2005 - Neonatal lupus manifests as isolated neutropenia and mildly abnormal liver functionsSivalingam Kanagasegar
Arthritis and Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, 73104, USA
J Rheumatol 29:187-91. 2002..Furthermore, although other factors may contribute, these data suggest that anti-60 kDa Ro is directly involved in the pathogenesis of neutropenia... - Osteoprotegerin serum levels in Kawasaki disease: an additional potential marker in predicting children with coronary artery involvementGabriele Simonini
Department of Paediatrics, Rheumatology Unit, University of Florence, Florence, Italy
J Rheumatol 32:2233-8. 2005..We evaluated serum levels of OPG in a group of children with Kawasaki disease (KD), before immunoglobulin (IVIG) infusion and at 3-month followup... - Dual-energy X-ray aborptiometry assessment in children and adolescents with diseases that may affect the skeleton: the 2007 ISCD Pediatric Official PositionsNick Bishop
Sheffield University, Sheffield Childrens NHS Foundation Trust, Western Bank, Sheffield, UK
J Clin Densitom 11:29-42. 2008..Importantly, this document also highlights significant gaps in our knowledge, emphasizing areas for future research... - Anti-inflammatory and immunosuppressive drugs and reproductionMonika Østensen
Department of Rheumatology and Clinical Immunology Allergology, University Hospital of Bern, Switzerland
Arthritis Res Ther 8:209. 2006..Recommendations for drug treatment during pregnancy and lactation are given... - Localized scleroderma in childhood is not just a skin diseaseFrancesco Zulian
Dipartimento di Pediatria, Universita di Padova, Padua, Italy
Arthritis Rheum 52:2873-81. 2005..We studied the prevalence and clinical features of extracutaneous manifestations in a large cohort of children with juvenile localized scleroderma... - The Pediatric Rheumatology International Trials Organization criteria for the evaluation of response to therapy in juvenile systemic lupus erythematosus: prospective validation of the disease activity core setNicolino Ruperto
Pediatric Rheumatology International Trials Organization PRINTO, IRCCS G Gaslini, Universita di Genova, Pediatria II Reumatologia, Largo Gaslini, Genoa, Italy
Arthritis Rheum 52:2854-64. 2005..To validate and promulgate a core set of outcome measures for the evaluation of response to treatment in patients with juvenile systemic lupus erythematosus (SLE)... - Pregnancy and autoimmunity: maternal treatment and maternal disease influence on pregnancy outcomeAngela Tincani
Spedali Civili e Universita di Brescia, Brescia, Italy
Autoimmun Rev 4:423-8. 2005..However, information about long-term outcome of children exposed to immunosuppressive drugs "in utero" are still lacking and more efforts are needed in this research area... - A girl with a sore earFernanda Falcini
Department of Paediatrics-Rheumatology Unit, 50132 Florence, Italy
Lancet 362:1894. 2003 - Pediatric antiphospholipid syndromeRolando Cimaz
Departement de Pediatrie, Pavillon S, Hopital Edouard Herriot, 69437, Lyon, France
Rheum Dis Clin North Am 32:553-73. 2006..Studies on the outcome of pediatric APS and the relative risks of prolonged anticoagulation in children are necessary to determine the type and duration of anticoagulation therapy...