Rachele Ciccocioppo

Summary

Affiliation: University of Pavia
Country: Italy

Publications

  1. pmc The immune recognition of gluten in coeliac disease
    R Ciccocioppo
    First Department of Internal Medicine, IRCCS Policlinico San Matteo, University of Pavia, Italy
    Clin Exp Immunol 140:408-16. 2005
  2. doi request reprint Allogeneic hematopoietic stem cell transplantation may restore gluten tolerance in patients with celiac disease
    Rachele Ciccocioppo
    Clinica Medica I, Fondazione IRCCS Policlinico San Matteo, Universita degli Studi di Pavia, Piazzale Golgi 19, Pavia, Italy
    J Pediatr Gastroenterol Nutr 56:422-7. 2013
  3. pmc Mesenchymal stromal cell infusions as rescue therapy for corticosteroid-refractory adult autoimmune enteropathy
    Rachele Ciccocioppo
    Clinica Medica I, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Universita degli Studi di Pavia, Italy
    Mayo Clin Proc 87:909-14. 2012
  4. doi request reprint Autologous bone marrow-derived mesenchymal stromal cells in the treatment of fistulising Crohn's disease
    Rachele Ciccocioppo
    Clinica Medica I, Fondazione IRCCS Policlinico San Matteo, Universita degli Studi di Pavia, Pavia, Italy
    Gut 60:788-98. 2011
  5. ncbi request reprint Isolation and characterization of circulating tissue transglutaminase-specific T cells in coeliac disease
    R Ciccocioppo
    Center for the Study and Cure of Coeliac Disease, IRCCS Policlinico San Matteo Foundation, University of Pavia, Italy
    Int J Immunopathol Pharmacol 23:179-91. 2010
  6. doi request reprint Effects of gliadin stimulation on bone marrow-derived dendritic cells from HLA-DQ8 transgenic MICE
    R Ciccocioppo
    Center for the Study and Cure of Coeliac Disease, IRCCS San Matteo Hospital Foundation, University of Pavia, Italy
    Dig Liver Dis 40:927-35. 2008
  7. ncbi request reprint Serum bFGF and VEGF correlate respectively with bowel wall thickness and intramural blood flow in Crohn's disease
    Antonio Di Sabatino
    Gastroenterology Unit, IRCCS Policlinico S Matteo, University of Pavia, 27100, Italy
    Inflamm Bowel Dis 10:573-7. 2004
  8. doi request reprint Phenotypical/functional characterization of in vitro-expanded mesenchymal stromal cells from patients with Crohn's disease
    Maria Ester Bernardo
    Oncoematologia Pediatrica, Fondazione IRCCS Policlinico San Matteo, Universita di Pavia, Pavia, Italy
    Cytotherapy 11:825-36. 2009
  9. doi request reprint Mucosal changes induced by ischemia-reperfusion injury in a jejunal loop transplanted in oropharynx
    Antonio Di Sabatino
    First Department of Medicine, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Piazzale Golgi 19, 27100, Pavia, Italy
    Intern Emerg Med 8:317-25. 2013
  10. pmc Role of the advanced glycation end products receptor in Crohn's disease inflammation
    Rachele Ciccocioppo
    Rachele Ciccocioppo, Venerina Imbesi, Vincenzo Boccaccio, Elena Betti, Giuseppina Cristina Cangemi, Gino Roberto Corazza, Department of Internal Medicine, Fondazione IRCCS Policlinico San Matteo, University of Pavia, 27100 Pavia, Italy
    World J Gastroenterol 19:8269-81. 2013

Collaborators

Detail Information

Publications23

  1. pmc The immune recognition of gluten in coeliac disease
    R Ciccocioppo
    First Department of Internal Medicine, IRCCS Policlinico San Matteo, University of Pavia, Italy
    Clin Exp Immunol 140:408-16. 2005
    ..These findings are the subject of the present review...
  2. doi request reprint Allogeneic hematopoietic stem cell transplantation may restore gluten tolerance in patients with celiac disease
    Rachele Ciccocioppo
    Clinica Medica I, Fondazione IRCCS Policlinico San Matteo, Universita degli Studi di Pavia, Piazzale Golgi 19, Pavia, Italy
    J Pediatr Gastroenterol Nutr 56:422-7. 2013
    ..These data suggest that allogeneic HSCT may lead to induction of gluten tolerance in patients with CD...
  3. pmc Mesenchymal stromal cell infusions as rescue therapy for corticosteroid-refractory adult autoimmune enteropathy
    Rachele Ciccocioppo
    Clinica Medica I, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Universita degli Studi di Pavia, Italy
    Mayo Clin Proc 87:909-14. 2012
    ..This case encourages the use of MSCs to treat patients with life-threatening, corticosteroid-refractory AIE and suggests that MSC infusion can attenuate, albeit transiently, the autoimmune attack...
  4. doi request reprint Autologous bone marrow-derived mesenchymal stromal cells in the treatment of fistulising Crohn's disease
    Rachele Ciccocioppo
    Clinica Medica I, Fondazione IRCCS Policlinico San Matteo, Universita degli Studi di Pavia, Pavia, Italy
    Gut 60:788-98. 2011
    ..We therefore investigated the feasibility, safety and efficacy of serial intrafistular injections of autologous bone marrow-derived mesenchymal stromal cells (MSCs) in the treatment of fistulising Crohn's disease...
  5. ncbi request reprint Isolation and characterization of circulating tissue transglutaminase-specific T cells in coeliac disease
    R Ciccocioppo
    Center for the Study and Cure of Coeliac Disease, IRCCS Policlinico San Matteo Foundation, University of Pavia, Italy
    Int J Immunopathol Pharmacol 23:179-91. 2010
    ....
  6. doi request reprint Effects of gliadin stimulation on bone marrow-derived dendritic cells from HLA-DQ8 transgenic MICE
    R Ciccocioppo
    Center for the Study and Cure of Coeliac Disease, IRCCS San Matteo Hospital Foundation, University of Pavia, Italy
    Dig Liver Dis 40:927-35. 2008
    ..We aimed to study the immunological effects of gliadin stimulation on dendritic cells (DCs) from HLA-DQ8 transgenic and BALB/c mice...
  7. ncbi request reprint Serum bFGF and VEGF correlate respectively with bowel wall thickness and intramural blood flow in Crohn's disease
    Antonio Di Sabatino
    Gastroenterology Unit, IRCCS Policlinico S Matteo, University of Pavia, 27100, Italy
    Inflamm Bowel Dis 10:573-7. 2004
    ..The higher levels of VEGF in those patients with increased intramural blood flow suggests that VEGF may be considered a marker of angiogenesis in this condition...
  8. doi request reprint Phenotypical/functional characterization of in vitro-expanded mesenchymal stromal cells from patients with Crohn's disease
    Maria Ester Bernardo
    Oncoematologia Pediatrica, Fondazione IRCCS Policlinico San Matteo, Universita di Pavia, Pavia, Italy
    Cytotherapy 11:825-36. 2009
    ..The aim of the study was in vitro characterization of MSC from active CD patients for future clinical application...
  9. doi request reprint Mucosal changes induced by ischemia-reperfusion injury in a jejunal loop transplanted in oropharynx
    Antonio Di Sabatino
    First Department of Medicine, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Piazzale Golgi 19, 27100, Pavia, Italy
    Intern Emerg Med 8:317-25. 2013
    ..We identified alterations in lymphocyte infiltration, mucosal architecture and epithelial cell turnover, which may give a window to mechanisms of small bowel ischemia-reperfusion in humans...
  10. pmc Role of the advanced glycation end products receptor in Crohn's disease inflammation
    Rachele Ciccocioppo
    Rachele Ciccocioppo, Venerina Imbesi, Vincenzo Boccaccio, Elena Betti, Giuseppina Cristina Cangemi, Gino Roberto Corazza, Department of Internal Medicine, Fondazione IRCCS Policlinico San Matteo, University of Pavia, 27100 Pavia, Italy
    World J Gastroenterol 19:8269-81. 2013
    ..To investigate the level of mucosal expression and the involvement of the receptor for the advanced glycation end products (RAGE) in delayed apoptosis and tumor necrosis factor (TNF)-α production in Crohn's disease (CD)...
  11. ncbi request reprint Altered expression, localization, and phosphorylation of epithelial junctional proteins in celiac disease
    Rachele Ciccocioppo
    First Department of Medicine, IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy
    Am J Clin Pathol 125:502-11. 2006
    ....
  12. ncbi request reprint Matrix metalloproteinase pattern in celiac duodenal mucosa
    Rachele Ciccocioppo
    Gastroenterology Unit, IRCCS Policlinico San Matteo, University of Pavia, Italy
    Lab Invest 85:397-407. 2005
    ..In conclusion, our results show the presence of a peculiar MMP pattern in active CD strongly dominated by MMP-12, correlating either with IFN-gamma or the degree of mucosal damage...
  13. doi request reprint Validation of the Italian translation of the Inflammatory Bowel Disease Questionnaire
    Rachele Ciccocioppo
    Center for the Study and Cure of Inflammatory Bowel Disease, First Department of Medicine, IRCCS Policlinico San Matteo Foundation, University of Pavia, Pavia, Italy
    Dig Liver Dis 43:535-41. 2011
    ..The McMaster Inflammatory Bowel Disease Questionnaire (IBDQ) is the most used specific instrument...
  14. doi request reprint TCRβ clonality improves diagnostic yield of TCRγ clonality in refractory celiac disease
    Vittorio Perfetti
    Coeliac Centre First Department of Internal Medicine, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy
    J Clin Gastroenterol 46:675-9. 2012
    ..Meanwhile, the Biomedicine and Health-2 Concerted Action has made available standardized, highly specific, and sensitive PCR assays not only for Vγ but also for Vβ...
  15. doi request reprint Anemia of chronic disease and defective erythropoietin production in patients with celiac disease
    Gaetano Bergamaschi
    Department of Internal Medicine, University of Pavia Medical School and Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    Haematologica 93:1785-91. 2008
    ..Although celiac disease is a chronic condition characterized by an intense inflammatory response of the intestinal mucosa, scant data are available about the prevalence of anemia of chronic disease in celiac disease...
  16. ncbi request reprint Depletion of immunoglobulin M memory B cells is associated with splenic hypofunction in inflammatory bowel disease
    Antonio Di Sabatino
    Gastroenterology Unit, IRCCS Policlinico S Matteo, University of Pavia, Pavia, Italy
    Am J Gastroenterol 100:1788-95. 2005
    ....
  17. ncbi request reprint Is a life-long gluten-free diet for patients with celiac disease successful?
    Rachele Ciccocioppo
    IRCCS Policlinico San Matteo, University of Pavia, Italy
    Nat Clin Pract Gastroenterol Hepatol 2:290-1. 2005
  18. ncbi request reprint Increased enterocyte apoptosis in inflamed areas of Crohn's disease
    Antonio Di Sabatino
    Gastroenterology Unit, IRCCS Policlinico S Matteo, University of Pavia, Pavia, Italy
    Dis Colon Rectum 46:1498-507. 2003
    ....
  19. ncbi request reprint Treating ETTCL: A matter of early diagnosis and chemotherapy strategies
    R Ciccocioppo
    First Department of Internal Medicine, IRCCS Policlinico San Matteo Foundation, University of Pavia, Italy
    Dig Liver Dis 39:642-5. 2007
  20. pmc Epithelium derived interleukin 15 regulates intraepithelial lymphocyte Th1 cytokine production, cytotoxicity, and survival in coeliac disease
    A Di Sabatino
    First Department of Medicine, IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy
    Gut 55:469-77. 2006
    ..We aimed to better understand the IL-15 driven effects on IEL underlying mucosal damage and lymphomagenesis in coeliac disease (CD)...
  21. pmc Mechanisms of villous atrophy in autoimmune enteropathy and coeliac disease
    R Ciccocioppo
    Gastroenterology Unit, IRCCS Policlinico S Matteo, University of Pavia, Italy
    Clin Exp Immunol 128:88-93. 2002
    ..These results point to enterocyte autoantibody-dependent cellular cytotoxicity as the prevalent mechanism of increased enterocyte apoptosis in autoimmune enteropathy but not in coeliac disease...
  22. pmc Apoptosis and peripheral blood lymphocyte depletion in coeliac disease
    A Di Sabatino
    Gastroenterology Unit, IRCCS Policlinico S. Matteo, University of Pavia, Pavia, Italy
    Immunology 103:435-40. 2001
    ..This increased apoptosis could be responsible for both lymphopenia and immunogenic exposure of phospholipids with subsequent production of autoantibodies...
  23. pmc Intraepithelial and lamina propria lymphocytes show distinct patterns of apoptosis whereas both populations are active in Fas based cytotoxicity in coeliac disease
    A Di Sabatino
    Gastroenterology Unit, IRCCS Policlinico S Matteo, University of Pavia, Pavia, Italy
    Gut 49:380-6. 2001
    ..Increased LPL apoptosis is likely to downregulate mucosal inflammation whereas decreased IEL apoptosis could be responsible for autoimmune and malignant complications of CD...