B Chini

Summary

Affiliation: University of Milan
Country: Italy

Publications

  1. pmc Selective and potent agonists and antagonists for investigating the role of mouse oxytocin receptors
    Marta Busnelli
    CNR, Institute of Neuroscience, Via Vanvitelli 32, 20129 Milano, Italy
    J Pharmacol Exp Ther 346:318-27. 2013
  2. doi request reprint G-protein-coupled receptors, cholesterol and palmitoylation: facts about fats
    Bice Chini
    CNR Institute of Neuroscience, Milan, Italy
    J Mol Endocrinol 42:371-9. 2009
  3. ncbi request reprint Agonist selectivity in the oxytocin/vasopressin receptor family: new insights and challenges
    B Chini
    CNR Institute of Neuroscience, Department of Pharmacology, University of Milan, Via Vanvitelli 32, 20129 Milan, Italy
    Biochem Soc Trans 35:737-41. 2007
  4. ncbi request reprint G-protein coupled receptors in lipid rafts and caveolae: how, when and why do they go there?
    B Chini
    CNR Institute of Neuroscience, Cellular and Molecular Pharmacology Section, Milan, Italy
    J Mol Endocrinol 32:325-38. 2004
  5. ncbi request reprint Molecular basis of ligand binding and receptor activation in the oxytocin and vasopressin receptor family
    B Chini
    CNR Cellular and Molecular Pharmacology Center, Department of Pharmacology, University of Milan, Italy
    Exp Physiol 85:59S-66S. 2000
  6. pmc Oxytocin stimulates migration and invasion in human endothelial cells
    M G Cattaneo
    Department of Pharmacology, University of Milano, Via Vanvitelli 32, Milano, Italy
    Br J Pharmacol 153:728-36. 2008
  7. pmc Improved radiotracing of oxytocin receptor-expressing tumours using the new [111In]-DOTA-Lys8-deamino-vasotocin analogue
    B Chini
    CNR Institute of Neuroscience, Cellular and Molecular Pharmacology Section, Via Vanvitelli 32, 20129 Milano, Italy
    Br J Cancer 89:930-6. 2003
  8. pmc Thioacylation is required for targeting G-protein subunit G(o1alpha) to detergent-insoluble caveolin-containing membrane domains
    F Guzzi
    Department of Experimental and Environmental Medicine and Medical Biotechnologies, University of Milano-Bicocca, Via Cadore 48, 20052 Monza, Italy
    Biochem J 355:323-31. 2001
  9. ncbi request reprint Oxytocin and oxytocin receptors in cancer cells and proliferation
    P Cassoni
    Department of Biomedical Sciences and Human Oncology, University of Torino, Torino, Italy
    J Neuroendocrinol 16:362-4. 2004
  10. pmc Tyr115 is the key residue for determining agonist selectivity in the V1a vasopressin receptor
    B Chini
    Unité INSERM 401, CCIPE rue de la Cardionille, Montpellier, France
    EMBO J 14:2176-82. 1995

Collaborators

Detail Information

Publications11

  1. pmc Selective and potent agonists and antagonists for investigating the role of mouse oxytocin receptors
    Marta Busnelli
    CNR, Institute of Neuroscience, Via Vanvitelli 32, 20129 Milano, Italy
    J Pharmacol Exp Ther 346:318-27. 2013
    ..These highly selective pharmacological tools will contribute to the investigation of the specific physiologic and pathologic roles of mOTR for the development of selective OT-based therapeutics. ..
  2. doi request reprint G-protein-coupled receptors, cholesterol and palmitoylation: facts about fats
    Bice Chini
    CNR Institute of Neuroscience, Milan, Italy
    J Mol Endocrinol 42:371-9. 2009
    ..This review briefly highlights how lipids of the membrane and the receptor themselves can influence GPCR organisation and functioning...
  3. ncbi request reprint Agonist selectivity in the oxytocin/vasopressin receptor family: new insights and challenges
    B Chini
    CNR Institute of Neuroscience, Department of Pharmacology, University of Milan, Via Vanvitelli 32, 20129 Milan, Italy
    Biochem Soc Trans 35:737-41. 2007
    ..The pharmacological properties and selectivity profiles of these bivalent ligands, which remain to be investigated, could lead to highly novel research tools and potential therapeutic agents...
  4. ncbi request reprint G-protein coupled receptors in lipid rafts and caveolae: how, when and why do they go there?
    B Chini
    CNR Institute of Neuroscience, Cellular and Molecular Pharmacology Section, Milan, Italy
    J Mol Endocrinol 32:325-38. 2004
    ..Finally, we review the growing evidence that lipid rafts and caveolae participate in the regulation of GPCR signalling by affecting both signalling selectivity and coupling efficacy...
  5. ncbi request reprint Molecular basis of ligand binding and receptor activation in the oxytocin and vasopressin receptor family
    B Chini
    CNR Cellular and Molecular Pharmacology Center, Department of Pharmacology, University of Milan, Italy
    Exp Physiol 85:59S-66S. 2000
    ....
  6. pmc Oxytocin stimulates migration and invasion in human endothelial cells
    M G Cattaneo
    Department of Pharmacology, University of Milano, Via Vanvitelli 32, Milano, Italy
    Br J Pharmacol 153:728-36. 2008
    ..Among these, human umbilical vein endothelial cells (HUVECs) respond to oxytocin with an increased proliferation, suggesting a possible role for the hormone in the regulation of angiogenesis...
  7. pmc Improved radiotracing of oxytocin receptor-expressing tumours using the new [111In]-DOTA-Lys8-deamino-vasotocin analogue
    B Chini
    CNR Institute of Neuroscience, Cellular and Molecular Pharmacology Section, Via Vanvitelli 32, 20129 Milano, Italy
    Br J Cancer 89:930-6. 2003
    ..These features makes radiolabelled DOTA-dLVT a very good candidate for the radiotargeting of OTR-expressing tumours...
  8. pmc Thioacylation is required for targeting G-protein subunit G(o1alpha) to detergent-insoluble caveolin-containing membrane domains
    F Guzzi
    Department of Experimental and Environmental Medicine and Medical Biotechnologies, University of Milano-Bicocca, Via Cadore 48, 20052 Monza, Italy
    Biochem J 355:323-31. 2001
    ....
  9. ncbi request reprint Oxytocin and oxytocin receptors in cancer cells and proliferation
    P Cassoni
    Department of Biomedical Sciences and Human Oncology, University of Torino, Torino, Italy
    J Neuroendocrinol 16:362-4. 2004
    ....
  10. pmc Tyr115 is the key residue for determining agonist selectivity in the V1a vasopressin receptor
    B Chini
    Unité INSERM 401, CCIPE rue de la Cardionille, Montpellier, France
    EMBO J 14:2176-82. 1995
    ..Our results indicate that the interaction between peptide residue 8 and the receptor residue at position 115 is not only crucial for agonist high affinity binding but also for receptor selectivity...
  11. ncbi request reprint Chromosomal localization and physical linkage of the genes encoding the human alpha 3, alpha 5, and beta 4 neuronal nicotinic receptor subunits
    E Raimondi
    Dipartimento di Genetica e Microbiologia A Buzzati Traverso, Pavia, Italy
    Genomics 12:849-50. 1992