Research Topics
| A CherubiniSummaryAffiliation: University of Perugia Country: Italy Publications
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Publications
Role of antioxidants in atherosclerosis: epidemiological and clinical updateA Cherubini
Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia Medical School, Policlinico Monteluce, Padiglione E, Via Brunamonti, 06122, Perugia Italy
Curr Pharm Des 11:2017-32. 2005..Future studies should probably select patients in a context of high-oxidative stress / low-antioxidant defence, to verify if antioxidants may really prove useful as therapeutic anti-atherosclerotic agents...
Predictors of hospitalization in Italian nursing home residents: the U.L.I.S.S.E. projectAntonio Cherubini
Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia Medical School, Italy
J Am Med Dir Assoc 13:84.e5-10. 2012..To examine resident and facility characteristics associated with hospitalization in a cohort of Italian older nursing home residents...- Dietary antioxidants as potential pharmacological agents for ischemic strokeA Cherubini
Department of Clinical and Experimental Medicine, Institute of Gerontology and Geriatrics, Policlinico Monteluce, Pad E, Via Brunamonti, 51, 06100, Perugia, Italy
Curr Med Chem 15:1236-48. 2008.... - Potential markers of oxidative stress in strokeAntonio Cherubini
Institute of Gerontology and Geriatrics, University of Perugia Medical School, Policlinico Monteluce Pad E, Via Brunamonti 51, 06122 Perugia, Italy
Free Radic Biol Med 39:841-52. 2005.... - The prevention of adverse drug reactions in older subjectsAntonio Cherubini
Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia Medical School, Italy
Curr Drug Metab 12:652-7. 2011.... 
Low plasma N-3 fatty acids and dementia in older persons: the InCHIANTI studyAntonio Cherubini
Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
J Gerontol A Biol Sci Med Sci 62:1120-6. 2007..N-3 fatty acids (FA) have an important role in brain development and function. However, there is conflicting evidence concerning the relationship between n-3 FA and dementia in older persons...- Comparative effects of lercanidipine, lacidipine, and nifedipine gastrointestinal therapeutic system on blood pressure and heart rate in elderly hypertensive patients: the ELderly and LErcanidipine (ELLE) studyAntonio Cherubini
Sezione di Gerontologia e Geriatria, Perugia University Medical School, Via Brunamonti, Policlino Monteluce, I 06122, Perugia, Italy
Arch Gerontol Geriatr 37:203-12. 2003..5%) and the nifedipine group (10.1%). These data demonstrate that lercanidipine is effective in lowering blood pressure in older adult hypertensive patients while maintaining a superior tolerability and safety profile... - The persistent exclusion of older patients from ongoing clinical trials regarding heart failureAntonio Cherubini
Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, Policlinico Santa Maria della Misericordia, University of Perugia Medical School, Piazzale Menghini 1, 06156 Perugia PG, Italy
Arch Intern Med 171:550-6. 2011..A good example is heart failure. Therefore, we investigated the extent of exclusion of older individuals in ongoing clinical trials regarding heart failure... - Vitamin E levels, cognitive impairment and dementia in older persons: the InCHIANTI studyAntonio Cherubini
Institute of Gerontology and Geriatrics, University of Perugia Medical School, Department of Clinical and Experimental Medicine, Via Brunamonti, Policlinico Monteluce, Padiglione E, Perugia 06122, Italy
Neurobiol Aging 26:987-94. 2005..This study supports the notion that higher vitamin E plasma levels might provide significant protection against cognitive impairment and dementia in elderly subjects... - Antioxidant profile and early outcome in stroke patientsA Cherubini
Institute of Gerontology and Geriatrics, Perugia University Hospital and Medical School, Italy
Stroke 31:2295-300. 2000..The purpose of this study was to investigate the time course of plasma antioxidant changes in ischemic stroke patients... - Plasma antioxidants and longevity: a study on healthy centenariansP Mecocci
Sezione di Gerontologia e Geriatria, Dipartimento di Medicina Clinica e Sperimentale, Universita di Perugia, Perugia, Italy
Free Radic Biol Med 28:1243-8. 2000..From these results, it is evident that healthy centenarians show a particular profile in which high levels of vitamin A and vitamin E seem to be important in guaranteeing their extreme longevity... - Relationship between low levels of high-density lipoprotein cholesterol and dementia in the elderly. The InChianti studyG Zuliani
Department of Clinical and Experimental Medicine, Section of Internal Medicine, Gerontology and Geriatrics, University of Ferrara, Via Savonarola 9, 44100 Ferrara, Italy
J Gerontol A Biol Sci Med Sci 65:559-64. 2010..To evaluate the association between plasma lipid fractions and the prevalence of dementia in a large sample of Italian older individuals... - Plasma levels of lipophilic antioxidants in very old patients with type 2 diabetesM C Polidori
Institute of Gerontology and Geriatrics, Perugia University Hospital, Perugia, Italy
Diabetes Metab Res Rev 16:15-9. 2000..This evidence is limited in elderly patients with non-insulin dependent diabetes, in which age- and disease-related production of reactive oxygen species might exert synergistic damaging effects on tissues and organs... - Plasma antioxidants are similarly depleted in mild cognitive impairment and in Alzheimer's diseaseP Rinaldi
Department of Gerontology and Geriatrics, University of Perugia, Policlinico Monteluce-Pad. E, Via Brunamonti 51, 06126 Perugia, Italy
Neurobiol Aging 24:915-9. 2003.... - High vitamin E plasma levels and low low-density lipoprotein oxidation are associated with the absence of atherosclerosis in octogenariansA Cherubini
Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
J Am Geriatr Soc 49:651-4. 2001..31-0.91) were independently associated with VASA. CONCLUSIONS: These results suggest that an appropriate level of vitamin E and a low level of LDL oxidation might be important for reaching advanced age without developing atherosclerosis... - Impact of the earthquake of September 26, 1997 in Umbria, Italy on the socioenvironmental and psychophysical conditions of an elderly populationP Mecocci
Department of Gerontology and Geriatrics, University of Perugia, Italy
Aging (Milano) 12:281-6. 2000..These observations suggest that, after natural disasters, emergency programs should be more adapted to elderly people, whose needs and expectations are often different from those of young adults... - Physical activity and oxidative stress during agingM C Polidori
Institute of Gerontology and Geriatrics, Perugia University Hospital, Italy
Int J Sports Med 21:154-7. 2000.... - Oxidative stress in brain aging, neurodegenerative and vascular diseases: an overviewE Mariani
Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Policlinico Monteluce-Padiglione E, Via Brunamonti 51, 06122 Perugia Italy
J Chromatogr B Analyt Technol Biomed Life Sci 827:65-75. 2005..Particular attention will be given to the current knowledge about the biomarkers of oxidative stress that can be possibly used to monitor their severity and outcome... - Marked decrease in plasma antioxidants in aged osteoporotic women: results of a cross-sectional studyDario Maggio
Gerontology and Geriatrics, University of Perugia, 06122 Perugia, Italy
J Clin Endocrinol Metab 88:1523-7. 2003..Our results reveal that antioxidant defenses are markedly decreased in osteoporotic women. The mechanisms underlying antioxidant depletion and its relevance to the pathogenesis of osteoporosis deserve further investigation... - Predictors of high level of burden and distress in caregivers of demented patients: results of an Italian multicenter studyP Rinaldi
Department of Gerontology and Geriatrics, University of Perugia, Perugia, Italy
Int J Geriatr Psychiatry 20:168-74. 2005..This might be helpful in planning the correct social/clinical/rehabilitative approach... - (1)H-MR spectroscopy differentiates mild cognitive impairment from normal brain agingM Catani
1Institute of Gerontology and Geriatrics, University of Perugia, Italy
Neuroreport 12:2315-7. 2001..The choline/creatine ratio was not significantly different among the three groups. These data suggest that MCI is different from normal brain aging, having a white matter biochemical pattern similar to AD... - Physical activity and cardiovascular health in the elderlyA Cherubini
Department of Clinical Medicine, Pharmacology and Pathology, University of Perugia, Italy
Aging (Milano) 10:13-25. 1998..Physicians should recommend moderate-intensity physical activity to sedentary older subjects, who are still the majority within the elderly population... - Uric acid and dementia in community-dwelling older personsCarmelinda Ruggiero
Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
Dement Geriatr Cogn Disord 27:382-9. 2009..Epidemiological studies found that hyperuricemia is associated with conditions leading to dementia. Our aim is to investigate the relationship between UA levels and dementia in older persons... - Omega-3 polyunsaturated fatty acids and immune-mediated diseases: inflammatory bowel disease and rheumatoid arthritisC Ruggiero
Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
Curr Pharm Des 15:4135-48. 2009..In both IBD and RA further clinical trials with large sample size are needed to clarify the efficacy of omega-3 PUFA as a treatment... - Peripheral non-enzymatic antioxidant changes with human aging: a selective status reportM C Polidori
Institute of Gerontology and Geriatrics, Perugia University Hospital, Italy
Biogerontology 2:99-104. 2001.... - Hip fracture in nursing homes: an Italian study on prevalence, latency, risk factors, and impact on mobilityD Maggio
Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Via Eugubina, Italy
Calcif Tissue Int 68:337-41. 2001..We also suggest that preserved mobility may represent an additional risk factor for hip fracture in nursing homes... - Vascular dementia Italian sulodexide study (VA.D.I.S.S.). Clinical and biological resultsL Parnetti
Section of Gerontology and Geriatrics, Perugia University, Italy
Thromb Res 87:225-33. 1997..A parallel improvement of G.B.S. Rating Scale for dementia scores was observed in Sdx group. These results seem to indicate that sulodexide treatment can have positive effects in vascular dementia... - Cognitive impairment is the major risk factor for development of geriatric syndromes during hospitalization: results from the GIFA studyPatrizia Mecocci
Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Policlinico Monteluce Padiglione E, Via Brunamonti 51, IT 06122 Perugia, Italy
Dement Geriatr Cogn Disord 20:262-9. 2005..To detect the main factors associated with the occurrence of specific geriatric syndromes (namely pressure sores, fecal incontinence, urinary incontinence and falls) in elderly patients during hospitalization... - [Impact of population aging on the social and the health care system: need for a new model of long-term care]Umberto Senin
Sezione di Gerontologia e Geriatria, Dipartimento di Medicina Clinica e Sperimentale, Scuola di Specializzazione in Geriatria, Universita degli Studi di Perugia
Ann Ital Med Int 18:6-15. 2003.... - Use of artificial networks in clinical trials: a pilot study to predict responsiveness to donepezil in Alzheimer's diseasePatrizia Mecocci
Department of Gerontology and Geriatrics, University of Perugia, Perugia, Italy
J Am Geriatr Soc 50:1857-60. 2002..To evaluate the accuracy of artificial neural networks compared with discriminant analysis in classifying positive and negative response to the cholinesterase inhibitor donepezil in a group of Alzheimer's disease (AD) patients... - Depression in the elderly: new concepts and therapeutic approachesPatrizia Mecocci
Section of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
Aging Clin Exp Res 16:176-89. 2004.... - Lymphocyte oxidative DNA damage and plasma antioxidants in Alzheimer diseasePatrizia Mecocci
Institute of Gerontology and Geriatrics, University of Perugia, Via Eugubina 42, 06122 Perugia, Italy
Arch Neurol 59:794-8. 2002..A large body of experimental evidence suggests that in Alzheimer disease (AD) pathogenesis an important role is played by oxidative stress, but there is still a lack of data on in vivo markers of free radical-induced damage... - Validation of the Italian version of the falls efficacy scale international (FES-I) and the short FES-I in community-dwelling older personsC Ruggiero
Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Policlinico Santa Maria della Misericordia, Perugia, Italy
Arch Gerontol Geriatr 49:211-9. 2009..The Short FES-I is highly comparable with the FES-I. We conclude that the FES-I and the Short FES-I are excellent instruments to asses FF in Italian older subjects and they may be used in future research projects and clinical trials... - Antioxidants and bone turnover in involutional osteoporosisD Maggio
University of Perugia, Perugia, Italy
J Endocrinol Invest 25:101-2. 2002 - Hypertension and cognitive function in the elderlyAntonio Cherubini
Gerontology and Geriatrics, University of Perugia, Perugia, Italy
Am J Ther 14:533-54. 2007..Furthermore, these are ten of the other essential cerebral or systematic pathologies present that would be able to produce a dementia syndrome... - Risk factors for short-term mortality in older subjects with acute ischemic strokeGiovanni Zuliani
Department of Clinical and Experimental Medicine, Section of Internal Medicine, Gerontology and Geriatrics, University of Ferrara, Ferrara, Italy
Gerontology 52:231-6. 2006..The identification of predictors for mortality after stroke has a major importance for clinicians in order to allow the implementation of therapeutic and preventive strategies... - Validation of the five-item geriatric depression scale in elderly subjects in three different settingsPatrizia Rinaldi
Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia Medical School, Italy
J Am Geriatr Soc 51:694-8. 2003..84). Similar values were obtained in each setting and in both sexes. CONCLUSION: The five-item GDS is as effective as the 15-item GDS for the screening of depression in cognitively intact older subjects... - Hypertension and cognitive function in the elderlyAntonio Cherubini
Gerontology and Geriatrics, University of Perugia, Perugia, Italy
Dis Mon 56:106-47. 2010..Furthermore, these are ten of the other essential cerebral or systematic pathologies present that would be able to produce a dementia syndrome... - Conversion of MCI to dementia: Role of proton magnetic resonance spectroscopyAntonio Metastasio
Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Via Brunamonti 51, 06122 Perugia, Italy
Neurobiol Aging 27:926-32. 2006..48+/-0.08) and sMCI (1.65+/-0.12) and between pMCI and controls (1.63+/-0.16) in the left hemisphere, suggesting that this metabolic alteration can be detected before the clinical appearance of dementia... - Treatment with angiotensin-converting enzyme inhibitors is associated with a reduction in short-term mortality in older patients with acute ischemic strokeGiovanni Zuliani
Department of Clinical and Experimental Medicine, Section of Internal Medicine, Gerontology and Geriatrics, University of Ferrara, 44100 Ferrara, Italy
J Gerontol A Biol Sci Med Sci 60:463-5. 2005..We tested the hypothesis that angiotensin-converting enzyme inhibitors (A-I) might affect short-term (30 day) mortality in older persons with severe acute ischemic stroke... - Interaction of CTSD and A2M polymorphisms in the risk for Alzheimer's diseaseElena Mariani
Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
J Neurol Sci 247:187-91. 2006..Our data suggest that the CTSD-T allele of the CTSD-C/T polymorphism is associated with an increased relative risk for late-onset AD and, more interestingly, the combination of CTSD-T with the A2M-G allele seems to increase this risk... - Potentially inappropriate drug prescriptions and risk of hospitalization among older, Italian, nursing home residents: the ULISSE projectCarmelinda Ruggiero
Department of Clinical and Experimental Medicine, Institute of Gerontology and Geriatrics, University of Perugia, Perugia, Italy
Drugs Aging 27:747-58. 2010..Little information is available about the prevalence of potentially inappropriate drug prescriptions (PIDPs) and the related health adverse outcomes among nursing home (NH) residents... - Cathepsin D polymorphism in Italian elderly subjects with sporadic late-onset Alzheimer's diseaseTiziana Ingegni
Department of Gerontology and Geriatrics, University of Perugia School of Medicine, Perugia, Italy
Dement Geriatr Cogn Disord 16:151-5. 2003..Our data indicate no significant association between this polymorphism and the risk of AD. Likewise there was no association between CTSD polymorphism and the apolipoprotein E genotype in the risk of developing AD... - Low levels of carotenoids and retinol in involutional osteoporosisDario Maggio
Institute of Gerontology and Geriatrics, University of Perugia, Policlinico Monteluce, Via Brunamonti, 06124 Perugia, Italy
Bone 38:244-8. 2006..Our study suggests a bone sparing effect of retinol, to which the provitamin A activity of some carotenoids might have contributed... - Proton magnetic resonance spectroscopy reveals similar white matter biochemical changes in patients with chronic hypertension and early Alzheimer's diseaseMarco Catani
Institute of Gerontology and Geriatrics, University of Perugia, Perugia, Italy
J Am Geriatr Soc 50:1707-10. 2002..We evaluated the cerebral white matter biochemical pattern in healthy older subjects, older patients with chronic hypertension, and patients with Alzheimer's disease (AD) using proton magnetic resonance spectroscopy (1H-MRS)... - Fighting against age discrimination in clinical trialsAntonio Cherubini
Institute of Gerontology and Geriatrics, Perugia University Medical School, Policlinico Santa Maria della Misericordia, Perugia, Italy
J Am Geriatr Soc 58:1791-6. 2010.... - Enhanced myocardial vitamin C accumulation in left ventricular hypertrophy in rats is not attenuated with transition to heart failureSusanne Rohrbach
Institute of Pathophysiology, Martin Luther University Halle Wittenberg, Germany
Eur J Heart Fail 10:226-32. 2008..Therefore, the accumulation of vitamin C in compensated hypertrophy and in decompensated failure excludes cardiac vitamin C deficiency as a primary factor to oxidative stress in this model... - The interplay between uric acid and antioxidants in relation to physical function in older personsCarmelinda Ruggiero
Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21225, USA
J Am Geriatr Soc 55:1206-15. 2007..To investigate the relationship between circulating uric acid (UA) levels and plasma antioxidants and whether antioxidant levels modulate the association between UA and physical function... - Usefulness of uric acid to predict changes in C-reactive protein and interleukin-6 in 3-year period in Italians aged 21 to 98 yearsCarmelinda Ruggiero
Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA
Am J Cardiol 100:115-21. 2007..In conclusion, our study suggests that in a population-based cohort, baseline UA and changes in circulating UA during 3 years of follow-up predict changes in circulating CRP independent of relevant confounders, including baseline IL-6... - Elderly patients with cognitive impairment have a high risk for functional decline during hospitalization: The GIFA StudyClaudio Pedone
Centro Medicina dell'Invecchiamento, Catholic University, Rome, Italy
J Gerontol A Biol Sci Med Sci 60:1576-80. 2005..CONCLUSIONS: Elderly patients with CIA have a higher risk for FD. New strategies should be implemented to prevent FD in patients with cognitive impairment, who account for a high percentage of older persons who are admitted to hospitals... - Effects of vitamin C and aspirin in ischemic stroke-related lipid peroxidation: results of the AVASAS (Aspirin Versus Ascorbic acid plus Aspirin in Stroke) StudyM Cristina Polidori
Institute of Biochemistry and Molecular Biology I, Heinrich-Heine University, , Germany
Biofactors 24:265-74. 2005..Further studies are warranted to clarify whether the use of vitamin C may add clinical long-term beneficial effects in patients with stroke... - Antioxidants and physical performance in elderly persons: the Invecchiare in Chianti (InCHIANTI) studyMatteo Cesari
Sticht Center on Aging, Wake Forest University Health Sciences, Winston Salem, NC 27157, USA
Am J Clin Nutr 79:289-94. 2004..Muscle strength and physical performance in old age might be related to the oxidative damage caused by free radicals... - Associations between vitamin D status and pain in older adults: the Invecchiare in Chianti studyGregory E Hicks
Department of Physical Therapy, University of Delaware, Newark, Delaware 19716, USA
J Am Geriatr Soc 56:785-91. 2008..To examine cross-sectional associations between vitamin D status and musculoskeletal pain and whether they differ by sex... - Lower plasma vitamin E levels are associated with the frailty syndrome: the InCHIANTI studyAlessandro Ble
Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, MD 21225, USA
J Gerontol A Biol Sci Med Sci 61:278-83. 2006..30; 95% confidence interval, 0.10-0.91). CONCLUSIONS: Our findings show an association between low circulating levels of one of the most important components of the human antioxidant system and the presence of frailty... - Relationship of plasma polyunsaturated fatty acids to circulating inflammatory markersLuigi Ferrucci
Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, National Institutes of Health, Harbor Hospital, 5th Floor, 3001 Hanover Street, Baltimore, MD 21225, USA
J Clin Endocrinol Metab 91:439-46. 2006..The protective effect of PUFAs is mediated by multiple mechanisms, including their antiinflammatory properties. The association of physiological PUFA levels with pro- and antiinflammatory markers has not been established... - Markers of inflammation, vitamin E and peripheral nervous system function: the InCHIANTI studyAngelo Di Iorio
Laboratory of Clinical Epidemiology, Department of Medicine and Sciences of Aging, University G D Annunzio, Via dei Vestini 5, 66013 Chieti Scalo, Italy
Neurobiol Aging 27:1280-8. 2006..The aim of this study was to characterize the decline in nerve conduction velocity in the peripheral nervous system over the aging process and to identify factors that, independent of age, affect nerve conduction velocity... - Plasma carotenoid and malondialdehyde levels in ischemic stroke patients: relationship to early outcomeM Cristina Polidori
Institute of Physiological Chemistry I, Heinrich Heine University, Dusseldorf, Germany
Free Radic Res 36:265-8. 2002..Among the carotenoids, only lutein plasma changes are associated with a poor early-outcome... - Serum micronutrient concentrations and decline in physical function among older personsBenedetta Bartali
Division of Nutritional Sciences, Cornell University, Ithaca, New York, USA
JAMA 299:308-15. 2008..The potential deleterious effect of poor nutrition on decline in physical function in older persons is unclear... - Bone density and hemoglobin levels in older persons: results from the InCHIANTI studyMatteo Cesari
Sticht Center on Aging, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, North Carolina, NC 27157, USA
Osteoporos Int 16:691-9. 2005..The bone loss associated with hemoglobin levels mainly occurs in the cortical bone. Women with lower hemoglobin levels demonstrate a higher bone loss than male counterparts... - Neurological examination findings to predict limitations in mobility and falls in older persons without a history of neurological diseaseLuigi Ferrucci
Longitudinal Studies Section, Clinical Research Branch, National Instituts on Aging, National Institute of Health, Baltimore, Maryland 21225, USA
Am J Med 116:807-15. 2004..To estimate the prevalence of neurological signs and their association with limitations in mobility and falls in a sample of older persons without known neurological disease... - Prescription of anti-oedema agents and short-term mortality in older patients with acute ischaemic strokeGiovanni Zuliani
2nd Department of Internal Medicine, University of Ferrara, Ferrara, Italy
Drugs Aging 21:273-8. 2004..The sample included patients aged over 65 years who were admitted to hospital for acute ischaemic stroke... - Serum IL-1beta levels in health and disease: a population-based study. 'The InCHIANTI study'Angelo Di Iorio
Laboratory of Clinical Epidemiology, Department of Medicine and Sciences of Aging, University G. D'Annunzio, Chieti, Italy
Cytokine 22:198-205. 2003..Our data could lend support to the hypothesis that IL-1beta is mainly involved in the functional alterations of cardiomyocytes under conditions marked by mononuclear cell infiltration and by downregulation of calcium... - Low plasma selenium concentrations and mortality among older community-dwelling adults: the InCHIANTI StudyFulvio Lauretani
Tuscany Regional Agency, Florence, Italy
Aging Clin Exp Res 20:153-8. 2008..We examined the relationship between plasma selenium levels at enrollment and all-cause mortality over a 6-year period among participants in the InCHIANTI study... - Sertraline treatment for depression associated with acute coronary syndromes: a cost analysis from the viewpoint of the Italian Healthcare SystemFabrizia Lattanzio
Scientific Direction, Italian National Research Centre on Aging INRCA, 60124 Ancona, Italy
Aging Clin Exp Res 20:76-80. 2008..With the SADHART database, a cost analysis was carried out to determine the economic consequences of treating DD after ACS in the perspective of the Italian Healthcare System... - Editorial comment--Elderly stroke patient at risk for dementia: in search of a profileAntonio Cherubini
Stroke 34:2445. 2003 - The Caregiver Burden Inventory in evaluating the burden of caregivers of elderly demented patients: results from a multicenter studyMartina Marvardi
Dept of Gerontology and Geriatrics, University of Perugia
Aging Clin Exp Res 17:46-53. 2005..CONCLUSIONS: The CBI proved to be an effective multidimensional tool for evaluating the impact of burden on many aspects of caregivers' lives... - Low cholesterol levels are associated with short-term mortality in older patients with ischemic strokeGiovanni Zuliani
2nd Department of Internal Medicine, University of Ferrara, Italy
J Gerontol A Biol Sci Med Sci 59:293-7. 2004..We evaluated the association between TC levels and 30-day mortality in a sample of older patients with acute ischemic stroke... - Uric acid and inflammatory markersCarmelinda Ruggiero
Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, NIH, Baltimore, MD, USA
Eur Heart J 27:1174-81. 2006..Epidemiological studies have recently shown that UA may be a risk factor for cardiovascular diseases and a negative prognostic marker for mortality in subjects with pre-existing heart failure... - Urinary calcium is a determinant of bone mineral density in elderly men participating in the InCHIANTI studyGiuseppe Vezzoli
Division of Nephrology Dialysis and Hypertension, IRCCS San Raffaele Hospital, Postgraduate School of Nephrology, Vita Salute University, Milan, Italy
Kidney Int 67:2006-14. 2005.... - HPLC-tandem mass spectrometric method to characterize resveratrol metabolism in humansMireia Urpi Sarda
Nutrition and Food Science Department, CeRTA, Pharmacy School, University of Barcelona, Barcelona, Spain
Clin Chem 53:292-9. 2007..We sought to develop a method for nutritional analysis of resveratrol, a phenolic compound with purported health-promoting properties, and to determine all resveratrol metabolites... - Association between vitamin D status and physical performance: the InCHIANTI studyDenise K Houston
Department of Internal Medicine, Section on Gerontology and Geriatric Medicine, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
J Gerontol A Biol Sci Med Sci 62:440-6. 2007..Vitamin D status has been hypothesized to play a role in musculoskeletal function. Using data from the InCHIANTI study, we examined the association between vitamin D status and physical performance... - Rapidly progressive aphasic dementia with motor neuron disease: a distinctive clinical entityMarco Catani
Institute of Psychiatry, London, UK
Dement Geriatr Cogn Disord 17:21-8. 2004..These findings support the conclusion that MND with rapidly progressive aphasic dementia is a distinctive clinical entity within the group of FTD-MND... - From chronic low back pain to disability, a multifactorial mediated pathway: the InCHIANTI studyAngelo Di Iorio
Department of Medicine and Sciences of Aging, Laboratory of Clinical Epidemiology, University G d Annunzio Chieti, Italy
Spine (Phila Pa 1976) 32:E809-15. 2007..Clinicoepidemiologic study in the Chianti area (Tuscany, Italy)... - Axonal injury within language network in primary progressive aphasiaMarco Catani
Institute of Psychiatry, London, United Kingdom
Ann Neurol 53:242-7. 2003..The marked difference in the distribution of N-acetylaspartate to creatine between PPA and Alzheimer's disease suggests that proton magnetic resonance spectroscopy may help to differentiate between these two conditions...