Daniela Cecconi

Summary

Affiliation: University of Verona
Country: Italy

Publications

  1. pmc Polar electrophoresis: shape of two-dimensional maps is as important as size
    Renato Millioni
    Department of Medicine, University of Padova, Padova, Italy
    PLoS ONE 7:e30911. 2012
  2. doi request reprint Proteomic analysis of Oenococcus oeni freeze-dried culture to assess the importance of cell acclimation to conduct malolactic fermentation in wine
    Daniela Cecconi
    Dipartimento di Biotecnologie, University of Verona, Verona, Italy
    Electrophoresis 30:2988-95. 2009
  3. doi request reprint Changes in amniotic fluid and umbilical cord serum proteomic profiles of foetuses with intrauterine growth retardation
    Daniela Cecconi
    Dipartimento di Biotecnologie, Laboratorio di Proteomica e Spettrometria di Massa, Universita degli Studi di Verona, Verona, Italy
    Electrophoresis 32:3630-7. 2011
  4. doi request reprint Proteomics in pancreatic cancer research
    Daniela Cecconi
    Department of Biotechnology, University of Verona, Verona, Italy
    Proteomics 11:816-28. 2011
  5. doi request reprint Effect of tannic acid on Lactobacillus plantarum wine strain during starvation: A proteomic study
    Daniela Cecconi
    Dipartimento di Biotecnologie, University of Verona, Italy
    Electrophoresis 30:957-65. 2009
  6. doi request reprint Synergistic effect of trichostatin A and 5-aza-2'-deoxycytidine on growth inhibition of pancreatic endocrine tumour cell lines: a proteomic study
    Daniela Cecconi
    Dipartimento di Biotecnologie, Laboratorio di Proteomica, Universita di Verona, Verona, Italy
    Proteomics 9:1952-66. 2009
  7. ncbi request reprint Proteomic analysis of pancreatic ductal carcinoma cells after combined treatment with gemcitabine and trichostatin A
    Daniela Cecconi
    University of Verona, Department of Agricultural and Industrial Biotechnologies, Verona, Italy
    J Proteome Res 4:1909-16. 2005
  8. ncbi request reprint Proteomic analysis of pancreatic endocrine tumor cell lines treated with the histone deacetylase inhibitor trichostatin A
    Daniela Cecconi
    Department of Science and Technologies, Section of Biochemical Methodologies, University of Verona, Verona, Italy
    Proteomics 7:1644-53. 2007
  9. ncbi request reprint Proteome analysis in the clinical chemistry laboratory: myth or reality?
    Pier Giorgio Righetti
    Department of Agricultural and Industrial Biotechnologies, University of Verona, Strada Le Grazie No 15, Verona 37134, Italy
    Clin Chim Acta 357:123-39. 2005
  10. ncbi request reprint Proteomic analysis of pancreatic ductal carcinoma cells treated with 5-aza-2'-deoxycytidine
    Daniela Cecconi
    Department of Agricultural and Industrial Biotechnologies, University of Verona, Verona, Italy
    Electrophoresis 24:4291-303. 2003

Collaborators

Detail Information

Publications40

  1. pmc Polar electrophoresis: shape of two-dimensional maps is as important as size
    Renato Millioni
    Department of Medicine, University of Padova, Padova, Italy
    PLoS ONE 7:e30911. 2012
    ..In conclusion, this novel gel format in the second dimension of 2D gels is seen as an important improvement of this technique, still one of the most popular in proteome analysis...
  2. doi request reprint Proteomic analysis of Oenococcus oeni freeze-dried culture to assess the importance of cell acclimation to conduct malolactic fermentation in wine
    Daniela Cecconi
    Dipartimento di Biotecnologie, University of Verona, Verona, Italy
    Electrophoresis 30:2988-95. 2009
    ..Finally, this proteomic study increased knowledge concerning the physiological changes in freeze-dried culture occurring with pre-inoculation procedures...
  3. doi request reprint Changes in amniotic fluid and umbilical cord serum proteomic profiles of foetuses with intrauterine growth retardation
    Daniela Cecconi
    Dipartimento di Biotecnologie, Laboratorio di Proteomica e Spettrometria di Massa, Universita degli Studi di Verona, Verona, Italy
    Electrophoresis 32:3630-7. 2011
    ....
  4. doi request reprint Proteomics in pancreatic cancer research
    Daniela Cecconi
    Department of Biotechnology, University of Verona, Verona, Italy
    Proteomics 11:816-28. 2011
    ..Finally, we discuss the recent improvements obtained in classical 2-DE and high-throughput proteomic strategies able to allow the overcoming of relevant proteomic drawbacks...
  5. doi request reprint Effect of tannic acid on Lactobacillus plantarum wine strain during starvation: A proteomic study
    Daniela Cecconi
    Dipartimento di Biotecnologie, University of Verona, Italy
    Electrophoresis 30:957-65. 2009
    ..The modulation of specific proteins correlates with the positive effect of TA on the survival of tannase-positive L. plantarum...
  6. doi request reprint Synergistic effect of trichostatin A and 5-aza-2'-deoxycytidine on growth inhibition of pancreatic endocrine tumour cell lines: a proteomic study
    Daniela Cecconi
    Dipartimento di Biotecnologie, Laboratorio di Proteomica, Universita di Verona, Verona, Italy
    Proteomics 9:1952-66. 2009
    ..A comparison between the patterns of proteins regulated by TSA or DAC in endocrine and ductal pancreatic cancer cell lines is also presented...
  7. ncbi request reprint Proteomic analysis of pancreatic ductal carcinoma cells after combined treatment with gemcitabine and trichostatin A
    Daniela Cecconi
    University of Verona, Department of Agricultural and Industrial Biotechnologies, Verona, Italy
    J Proteome Res 4:1909-16. 2005
    ..Our results demonstrate that the level of activation/repression of the proteins involved in these processes correlates with the growth inhibition and the apoptotic response of the cells subjected to single or combined drug treatment...
  8. ncbi request reprint Proteomic analysis of pancreatic endocrine tumor cell lines treated with the histone deacetylase inhibitor trichostatin A
    Daniela Cecconi
    Department of Science and Technologies, Section of Biochemical Methodologies, University of Verona, Verona, Italy
    Proteomics 7:1644-53. 2007
    ..et al.., Electrophoresis 2003; Cecconi, D. et al., J. Proteome Res. 2005) and place histone-deacetylases inhibitors among the potentially most powerful drugs for the treatment of pancreatic tumors...
  9. ncbi request reprint Proteome analysis in the clinical chemistry laboratory: myth or reality?
    Pier Giorgio Righetti
    Department of Agricultural and Industrial Biotechnologies, University of Verona, Strada Le Grazie No 15, Verona 37134, Italy
    Clin Chim Acta 357:123-39. 2005
    ....
  10. ncbi request reprint Proteomic analysis of pancreatic ductal carcinoma cells treated with 5-aza-2'-deoxycytidine
    Daniela Cecconi
    Department of Agricultural and Industrial Biotechnologies, University of Verona, Verona, Italy
    Electrophoresis 24:4291-303. 2003
    ..The significance of some of these major changes is discussed...
  11. ncbi request reprint Critical survey of quantitative proteomics in two-dimensional electrophoretic approaches
    Pier Giorgio Righetti
    Department of Agricultural and Industrial Biotechnologies, University of Verona, Verona, Italy
    J Chromatogr A 1051:3-17. 2004
    ..The latter reagent achieves 100% efficiency coupled to 100% specificity. The advantages and limitations of the various protocols are discussed...
  12. doi request reprint Signal transduction pathways of mantle cell lymphoma: a phosphoproteome-based study
    Daniela Cecconi
    Laboratorio di Proteomica, Dipartimento Scientifico e Tecnologico, University of Verona, Verona, Italy
    Proteomics 8:4495-506. 2008
    ..A second-level analysis identified MAPK1, CK2, CK1, PKCzeta, and PKCepsilon as candidate upstream molecules. Our study provides new insights in MCL pathogenesis and helps to form the basis for testing new target-specific therapeutics...
  13. pmc Phospho-proteomic analysis of mantle cell lymphoma cells suggests a pro-survival role of B-cell receptor signaling
    Chiara Pighi
    Department of Pathology and Diagnostics, University of Verona, P le Scuro 10, 37134, Verona, Italy
    Cell Oncol (Dordr) 34:141-53. 2011
    ..We have applied a high-throughput phospho-proteomic technique to MCL cell lines to identify activated pathways and we have then validated our data in both cell lines and tumor tissues...
  14. doi request reprint Improved instrumentation for large-size two-dimensional protein maps
    Renato Millioni
    Department of Clinical and Experimental Medicine, Chair of Metabolism, University of Padova, Padova, Italy
    Electrophoresis 31:3863-6. 2010
    ..In addition, this apparatus also includes a second power supply that allows the performance of electrophoresis at high amperage (400 mA) and a Peltier system that allows a 10-80°C temperature control...
  15. ncbi request reprint Proteomic changes in rat serum, polymorphonuclear and mononuclear leukocytes after chronic nicotine administration
    Chiara Piubelli
    Department of Agricultural and Industrial Biotechnologies, University of Verona, Verona, Italy
    Proteomics 5:1382-94. 2005
    ....
  16. doi request reprint A proteomic approach for evaluating the cell response to a novel histone deacetylase inhibitor in colon cancer cells
    Alberto Milli
    Dipartimento Scientifico e Tecnologico, Laboratorio di Proteomica, Universita degli Studi di Verona, Verona, Italy
    Biochim Biophys Acta 1784:1702-10. 2008
    ..We found that RC307 exposure modulates proteins that are involved in proliferation, cell cycle regulation, apoptosis, gene expression, as well as chromatin and cytoskeleton organization...
  17. ncbi request reprint Pros and cons of peptide isolectric focusing in shotgun proteomics
    Renato Millioni
    Department of Medicine, University of Padova, Via Giustiniani 2, 35121 Padova, Italy Proteomics Center of Padova University, VIMM and Padova University Hospital, Via G Orus 2 B, 35129 Padova, Italy
    J Chromatogr A 1293:1-9. 2013
    ..Finally, we give some general conclusions on this strategy, underlying its principal limitations...
  18. doi request reprint Comparative proteomic and phosphoproteomic profiling of pancreatic adenocarcinoma cells treated with CB1 or CB2 agonists
    Jessica Brandi
    Proteomics and Mass Spectrometry Laboratory, Department of Biotechnology, University of Verona, Verona, Italy
    Electrophoresis 34:1359-68. 2013
    ..Overall, the results reported might contribute to the development of a therapy based on cannabinoids for pancreatic adenocarcinoma...
  19. doi request reprint Serum proteomic analysis during nicotine self-administration, extinction and relapse in rats
    Daniela Cecconi
    Dipartimento Scientifico e Tecnologico, University of Verona, Verona, Italy
    Electrophoresis 29:1525-33. 2008
    ..This study showed that specific protein patterns related to the nicotine self-administration states exist in serum. Further development of this approach may provide biomarkers to assess dependence states of drug-taking individuals...
  20. ncbi request reprint Exploring the hidden human urinary proteome via ligand library beads
    Annalisa Castagna
    Department of Clinical and Experimental Medicine, Unit of Internal Medicine, University of Verona, Italy
    J Proteome Res 4:1917-30. 2005
    ..By comparing our data with those reported to the present, an additional 251 proteins could be added to the list, thus bringing the total unique gene products so far identified in human urines to ca. 800 species...
  21. doi request reprint Proteomic analysis of cellular response to novel proapoptotic agents related to atypical retinoids in human IGROV-1 ovarian carcinoma cells
    Alberto Milli
    Dipartimento di Biotecnologie, Laboratorio di Proteomica e Spettrometria di Massa, University of Verona, Strada Le Grazie 15, 37134, Verona, Italy
    J Proteome Res 10:1191-207. 2011
    ..By identifying proteins modulated by novel proapoptotic agents, this study provides insights into critical aspects of their mechanism of action...
  22. ncbi request reprint Proteomic changes involved in tenderization of bovine Longissimus dorsi muscle during prolonged ageing
    Rita Polati
    Department of Biotechnology, Proteomics and Mass Spectrometry Laboratory, University of Verona, Strada Le Grazie 15, 37134 Verona, Italy
    Food Chem 135:2052-69. 2012
    ..Furthermore, the data presented here demonstrated that meat maturation caused changes of the abundance of proteins involved in metabolic, structural, and stress related processes...
  23. ncbi request reprint Proteomic profiling of pancreatic ductal carcinoma cell lines treated with trichostatin-A
    Daniela Cecconi
    Department of Agricultural and Industrial Biotechnologies, University of Verona, Verona, Italy
    Electrophoresis 24:1871-8. 2003
    ..The modulation of these four proteins is consistent with our observation that TSA is able to inhibit cell growth of Paca44 by causing cell cycle arrest at the G2 phase and apoptotic cell death...
  24. doi request reprint Proteomic analysis of the compatible interaction between Vitis vinifera and Plasmopara viticola
    Alberto Milli
    Dept of Biotechnology, University of Verona, Verona, Italy
    J Proteomics 75:1284-302. 2012
    ....
  25. ncbi request reprint Proteomic analysis of rat cortical neurons after fluoxetine treatment
    Daniela Cecconi
    Department of Agricultural and Industrial Biotechnologies, University of Verona, Italy
    Brain Res 1135:41-51. 2007
    ....
  26. doi request reprint Female urinary proteomics: New insight into exogenous and physiological hormone-dependent changes
    Annalisa Castagna
    Department of Medicine, Unit of Internal Medicine, University of Verona, Italy
    Proteomics Clin Appl 5:343-53. 2011
    ..Clinical parameters and renin-angiotensin-aldosterone system (RAAS) components were also investigated, on the basis of the well-known relation linking sex female hormones and renin and aldosterone levels...
  27. doi request reprint Proteomic analysis of Arabidopsis halleri shoots in response to the heavy metals cadmium and zinc and rhizosphere microorganisms
    Silvia Farinati
    Department of Biotechnology, University of Verona, Verona, Italy
    Proteomics 9:4837-50. 2009
    ....
  28. doi request reprint Pseudomonas putida response to cadmium: changes in membrane and cytosolic proteomes
    Anna Manara
    Dipartimento di Biotecnologie, Universita degli Studi di Verona, Strada Le Grazie 15, 37134 Verona, Italy
    J Proteome Res 11:4169-79. 2012
    ..This analysis provides new insights into the adaptation mechanisms used by P. putida-Cd001 to survive in Cd-polluted environments...
  29. ncbi request reprint Proteomic approaches for studying chemoresistance in cancer
    Pier Giorgio Righetti
    University of Verona, Department of Industrial and Agricultural Biotechnologies, Laboratory of Proteome Science, Strada Le Grazie 15, Verona, Italy
    Expert Rev Proteomics 2:215-28. 2005
    ....
  30. ncbi request reprint Urinary protease inhibitor Serpin B3 is higher in women and is further increased in female patients affected by aldosterone producing adenoma
    Oliviero Olivieri
    Department of Medicine, Unit of Internal Medicine, University of Verona, P le L A Scuro10, Verona, Italy
    Mol Biosyst 10:1281-9. 2014
    ..In conclusion urine SB3 concentrations are physiologically much lower in males than in females. Hypertensive women, affected by APA, present urinary SB3 concentrations significantly higher than women affected by BAH. ..
  31. ncbi request reprint Protein nitration during defense response in Arabidopsis thaliana
    Daniela Cecconi
    Dipartimento di Biotecnologie, University of Verona, Verona, Italy
    Electrophoresis 30:2460-8. 2009
    ..These findings shed new light on the signaling functions of nitric oxide and reactive oxygen species, paving the way on studies on the role of this post-translational modification in plants...
  32. ncbi request reprint The proteome: anno Domini 2002
    Pier Giorgio Righetti
    Department of Agricultural and Industrial Biotechnologies, Faculty of Sciences, University of Verona, Verona, Italy
    Clin Chem Lab Med 41:425-38. 2003
    ..Some general conclusions are drawn on proteome analysis and we end this review by trying to decode the glass ball of the aruspex and answer the question: "Quo vadis, proteome"?..
  33. doi request reprint Improvements to polar 2-D electrophoresis for proteomic applications
    Rita Polati
    Department of Biotechnology, Proteomics and Mass Spectrometry Laboratory, University of Verona, Verona, Italy
    Amino Acids 46:1143-6. 2014
    ..Here, we describe how to load longer strips (e.g., 18-24 cm) on 2-PE and report some representative images for a qualitative assessment. ..
  34. doi request reprint Expression of α-amylase inhibitors in diploid Triticum species
    Gianni Zoccatelli
    Universita di Verona, Dipartimento di Biotecnologie, Verona, Italy
    Food Chem 135:2643-9. 2012
    ..Interestingly, no signal was observed within T.m. accessions. This makes T.m. an important candidate for the production of novel functional foods...
  35. doi request reprint Induction of apoptosis in Jeko-1 mantle cell lymphoma cell line by resveratrol: a proteomic analysis
    Daniela Cecconi
    Dipartimento Scientifico e Tecnologico, Laboratorio di Proteomica, University of Verona, Verona, Italy
    J Proteome Res 7:2670-80. 2008
    ..These findings may improve the understanding of mechanisms mediating the pro-apoptotic effects of resveratrol on MCL cells, and form the basis for its potential use as a therapeutic agent...
  36. doi request reprint Proteomic analysis of lymphoid and haematopoietic neoplasms: there's more than biomarker discovery
    Alberto Zamo
    Dip di Patologia, Sezione di Anatomia Patologica, Universita di Verona, Verona, Italy
    J Proteomics 73:508-20. 2010
    ....
  37. ncbi request reprint Red wine proteins: Two dimensional (2-D) electrophoresis and mass spectrometry analysis
    Federica Mainente
    Department of Biotechnology, University of Verona, Strada Le Grazie 15, 37134 Verona, Italy
    Food Chem 164:413-7. 2014
    ..Several well focalized protein spots were obtained and analyzed through mass-spectrometry. ..
  38. ncbi request reprint Quantitative analysis of two-dimensional gel-separated proteins using isotopically marked alkylating agents and matrix-assisted laser desorption/ionization mass spectrometry
    Sylvie Gehanne
    Computational, Analytical and Structural Sciences, Discovery Research, GlaxoSmithKline, Verona, Italy
    Rapid Commun Mass Spectrom 16:1692-8. 2002
    ..The described procedure has proved to be effective for comparative measurements of protein abundances within the investigated mixtures...
  39. doi request reprint 2D immunomic approach for the study of IgG autoantibodies in the experimental model of multiple sclerosis
    Alessia Farinazzo
    Department of Neuroscience, University of Verona, Italy
    J Neuroimmunol 232:63-7. 2011
    ..The present finding by 2D-immunomics of multiple neural proteins targeted by autoantibodies generated by a single antigen may help to explain the complex autoimmune response observed in multiple sclerosis...
  40. ncbi request reprint Characterization of the signaling pathway downstream p75 neurotrophin receptor involved in beta-amyloid peptide-dependent cell death
    Claudio Costantini
    Department of Pathology, Section of General Pathology, University of Verona, Strada Le Grazie 8, 37134 Verona, Italy
    J Mol Neurosci 25:141-56. 2005
    ..Therefore, our data suggest a signaling pathway in which Abeta peptide binds to p75NTR and activates p38 and JNK in a DD-dependent manner, followed by NF-kappaB translocation and p53 activation...