Research Topics
Genomes and GenesSpecies | Alessandra CassioSummaryAffiliation: University of Bologna Country: Italy Publications
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Detail Information
Publications
Current loss-of-function mutations in the thyrotropin receptor gene: when to investigate, clinical effects, and treatmentAlessandra Cassio
Department of Gynaecologic, Obstetric and Paediatric Sciences, S Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
J Clin Res Pediatr Endocrinol 5:29-39. 2013..Together with standard criteria we recommend also an accurate clinical work-up to select patients who are candidates for a LOF TSHR mutation...
Long-term clinical significance of thyroid autoimmunity in children with celiac diseaseAlessandra Cassio
Department of Pediatrics, University of Bologna, Via Massarenti 11, 40138 Bologna, Italy
J Pediatr 156:292-5. 2010..To evaluate the long-term outcome of thyroid function and autoimmunity in a large series of children with celiac disease...
Prospective evaluation of the natural course of idiopathic subclinical hypothyroidism in childhood and adolescenceMalgorzata Wasniewska
Department of Pediatrics, University of Messina, Messina, Italy
Eur J Endocrinol 160:417-21. 2009..To prospectively evaluate the course of subclinical hypothyroidism (SH) in children and adolescents with no underlying diseases and no risk factors, which might interfere with the progression of SH...
Peculiarities of Graves' disease in children and adolescents with Down's syndromeFilippo De Luca
Department of Pediatrics, University of Messina, 98124 Messina, Italy
Eur J Endocrinol 162:591-5. 2010..To compare the presentation and clinical course of Graves' disease (GD) in two pediatric populations consisting of 28 patients with Down's syndrome (DS) and 109 controls without DS respectively...
CYP21 genotype, adult height, and pubertal development in 55 patients treated for 21-hydroxylase deficiencyAntonio Balsamo
Department of Pediatrics, University of Bologna and S Orsola Malpighi Hospital, 40138 Bologna, Italy
J Clin Endocrinol Metab 88:5680-8. 2003..Genotypic analysis helped to interpret the height results of our cases and prospectively may represent a useful tool for improving the therapeutic choice and the height outcome...
Thyrotropin-stimulating hormone receptor gene analysis in pediatric patients with non-autoimmune subclinical hypothyroidismAnnalisa Nicoletti
Department of Gynaecologic, Obstetric, and Paediatric Sciences, S Orsola Malpighi Hospital, University of Bologna, 40138 Bologna, Italy
J Clin Endocrinol Metab 94:4187-94. 2009..Mutations in TSH receptor (TSHR) are notoriously associated with congenital hypothyroidism as well as with non-autoimmune subclinical hypothyroidism, a mild form of TSH resistance that is not as well characterized by diagnostic procedures...
In congenital hypothyroidism bone maturation at birth may be a predictive factor of psychomotor development during the first Year of life irrespective of other variables related to treatmentMalgorzata Wasniewska
Department of Pediatrics, University of Messina, Italy
Eur J Endocrinol 149:1-6. 2003....
A new DAX1 gene mutation associated with congenital adrenal hypoplasia and hypogonadotropic hypogonadismAntonio Balsamo
Department of Paediatrics, University of Bologna, Italy
Am J Med Genet A 135:292-6. 2005..Further investigations are needed to verify its causal role in AHC associated with HH...
Psychological and behavioural aspects in children and adolescents with congenital hypothyroidism diagnosed by neonatal screening: comparison between parents' and children's perceptionsNicoletta Bisacchi
Department of Gynaecologic, Obstetric and Paediatric Sciences, S Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
Eur J Endocrinol 164:269-76. 2011..To compare the psychological adjustment and behaviour of congenital hypothyroidism (CH) children and their parents with a control group...
Treatment for congenital hypothyroidism: thyroxine alone or thyroxine plus triiodothyronine?Alessandra Cassio
Department of Pediatrics, University of Bologna, Bologna, Italy
Pediatrics 111:1055-60. 2003..To compare the effects of therapy with thyroxine (T4) plus triiodothyronine (T3) versus T4 alone from the first days of life in screened congenital hypothyroid (CH) infants...
Reproductive outcome in patients treated and not treated for idiopathic early puberty: long-term results of a randomized trial in adultsAlessandra Cassio
Department of Gynecology, Obstetrics and Pediatrics, University of Bologna, Italy
J Pediatr 149:532-6. 2006..To evaluate the adult reproductive outcome in girls with early puberty who participated in a previous random study...
Active and total ghrelin concentrations in the newbornPiero Pirazzoli
Department of Pediatrics, Center for Applied Biomedical Research, S Orsola Malpighi Hospital, Bologna, Italy
J Pediatr Endocrinol Metab 18:379-84. 2005..An acyl modification is indispensable for biological activity. Acylated and desacylated forms of ghrelin are both present in the blood. No data exist about the ratio between active ghrelin and total ghrelin in the first period of life...
Acute suppurative thyroiditis in childhood: spontaneous closure of sinus pyriform fistula may occur even very earlyMalgorzata Wasniewska
Department of Pediatrics, University of Messina, Milano, Italy
J Pediatr Endocrinol Metab 20:75-7. 2007
