M O Carruba
Affiliation: University of Milan
- Efficacy and tolerability of moclobemide in bulimia nervosa: a placebo-controlled trialM O Carruba
Center for Study and Research on Obesity, Department of Preclinical Sciences, L Sacco Hospital, University of Milan, Italy
Int Clin Psychopharmacol 16:27-32. 2001....
- Nerve growth factor, beta3-adrenoceptor and uncoupling protein 1 expression in rat brown fat during postnatal developmentE Nisoli
Centre for Study and Research on Obesity, Department of Pharmacology, Chemotherapy and Medical Toxicology, LITA Vialba, Ospedale L Sacco, School of Medicine, University of Milan, Milano, Italy
Neurosci Lett 246:5-8. 1998..Relatively low levels of NGF were present in the brown fat of aged rats. Taken together, these results suggest that NGF may be responsible for regulating sympathetic innervation during the perinatal and adult periods...
- Tumor necrosis factor alpha mediates apoptosis of brown adipocytes and defective brown adipocyte function in obesityE Nisoli
Center for Study and Research on Obesity, LITA Vialba, L Sacco Hospital, University of Milan, Via G B Grassi 74, 20157 Milan, Italy
Proc Natl Acad Sci U S A 97:8033-8. 2000..These results indicate that TNF-alpha plays an important role in multiple aspects of brown adipose tissue biology and mediates the abnormalities that occur at this site in obesity...
- Protective effects of noradrenaline against tumor necrosis factor-alpha-induced apoptosis in cultured rat brown adipocytes: role of nitric oxide-induced heat shock protein 70 expressionE Nisoli
Center for Study and Research on Obesity, Department of Preclinical Sciences, LITA Vialba, L Sacco Hospital, Milan University, Milan, Italy
Int J Obes Relat Metab Disord 25:1421-30. 2001..To elucidate the effects and molecular mechanism(s) by means of which noradrenaline (NA) protects against the tumor necrosis factor (TNF)-alpha-induced apoptosis of brown adipocytes...
- New pharmacological tools for obesityE Nisoli
Center for Study and Research on Obesity, University of Milan, Department of Preclinical Sciences, L Sacco Hospital, Milan, Italy
J Endocrinol Invest 25:905-14. 2002..In the present review we concentrate on the first of these strategies, by underlining the new pharmacological tools which are presently studied...
- Induction of fatty acid translocase/CD36, peroxisome proliferator-activated receptor-gamma2, leptin, uncoupling proteins 2 and 3, and tumor necrosis factor-alpha gene expression in human subcutaneous fat by lipid infusionE Nisoli
Department of Preclinical Sciences, Center for Study and Research on Obesity, L Sacco Hospital, Univeristy of Milan, Italy
Diabetes 49:319-24. 2000....
- An assessment of the safety and efficacy of sibutramine, an anti-obesity drug with a novel mechanism of actionE Nisoli
Center for Study and Research on Obesity, Department of Preclinical Sciences, School of Medicine, University of Milan, LITA Vialba, L Sacco Hospital, Via G B Grassi, 74, Milan 20157, Italy
Obes Rev 1:127-39. 2000..Finally, sibutramine does not have the potential for abuse that is characteristic of amphetamine and it is indistinguishable from placebo in abuse potential studies...
- D2 dopamine receptor (DRD2) gene Taq1A polymorphism and the eating-related psychological traits in eating disorders (anorexia nervosa and bulimia) and obesityE Nisoli
Center for the Study and Research on Obesity, Department of Preclinical Sciences, Ospedale Sacco, University of Milan, Milan, Italy
Eat Weight Disord 12:91-6. 2007..For this reason, the aim of this study was to evaluate if the presence of A1 allele, in eating disorders and obesity, is associated with some particular psycho-pathological characteristics...
- Sibutramine lost and foundO Bosello
Department of Biomedical and Surgical Sciences, University of Verona, Italy
Eat Weight Disord 7:161-7. 2002..There is strong evidence supporting the usefulness of the correct use of sibutramine in the management of obesity...
- White adipocytes are less prone to apoptotic stimuli than brown adipocytes in rodentE Nisoli
Cell Death Differ 13:2154-6. 2006