Antonio Carrieri

Summary

Affiliation: University of Bari
Country: Italy

Publications

  1. doi request reprint Molecular determinants for nuclear receptors selectivity: chemometric analysis, dockings and site-directed mutagenesis of dual peroxisome proliferator-activated receptors α/γ agonists
    Antonio Carrieri
    Dipartimento di Farmacia Scienze del Farmaco, Università degli Studi di Bari Aldo Moro, Via E Orabona 4, 70125 Bari, Italy
    Eur J Med Chem 63:321-32. 2013
  2. ncbi request reprint Recent trends and future prospects in computational GPCR drug discovery: from virtual screening to polypharmacology
    Antonio Carrieri
    Dipartimento di Farmacia Scienze del Farmaco, Università degli Studi di Bari Aldo Moro Via Orabona 4, 70125 Bari, Italy
    Curr Top Med Chem 13:1069-97. 2013
  3. doi request reprint In vitro effectiveness of anidulafungin against Candida sp. biofilms
    Antonio Rosato
    Dipartimento di Farmacia Scienze del Farmaco, Università degli Studi di Bari Aldo Moro, Via Orabona 4, Bari Italy
    J Antibiot (Tokyo) 66:701-4. 2013
  4. ncbi request reprint N-aryl-2,6-dimethylbenzamides, a new generation of tocainide analogues as blockers of skeletal muscle voltage-gated sodium channels
    Marilena Muraglia
    Dipartimento di Farmacia Scienze del Farmaco, Sezione di Farmacologia, Università degli Studi di Bari Aldo Moro, Via E Orabona n 4, 70126 Bari, Italy
    J Med Chem 57:2589-600. 2014
  5. ncbi request reprint A convenient synthesis of lubeluzole and its enantiomer: evaluation as chemosensitizing agents on human ovarian adenocarcinoma and lung carcinoma cells
    Maria Maddalena Cavalluzzi
    Dipartimento di Farmacia Scienze del Farmaco, Università degli Studi di Bari Aldo Moro, Via E Orabona 4, 70126 Bari, Italy
    Bioorg Med Chem Lett 23:4820-3. 2013
  6. doi request reprint Structure-activity relationships in 1,4-benzodioxan-related compounds. 10. Novel α1-adrenoreceptor antagonists related to openphendioxan: synthesis, biological evaluation, and α1d computational study
    Antonio Carrieri
    Dipartimento Farmaco Chimico, Universita di Bari, Via Orabona 4, 70125 Bari, Italy
    Bioorg Med Chem 18:7065-77. 2010
  7. ncbi request reprint Biological profiling of anti-HIV agents and insight into CCR5 antagonist binding using in silico techniques
    Antonio Carrieri
    Dipartimento Farmaco Chimico, Universita degli Studi di Bari, Via Orabona 4, 70125 Bari, Italy
    ChemMedChem 4:1153-63. 2009
  8. doi request reprint 2-Aminobenzothiazole derivatives: search for new antifungal agents
    Alessia Catalano
    Dipartimento di Farmacia Scienze del Farmaco, Università degli Studi di Bari Aldo Moro, Via E Orabona n 4, 70125 Bari, Italy
    Eur J Med Chem 64:357-64. 2013
  9. ncbi request reprint 2D- and 3D-QSAR of tocainide and mexiletine analogues acting as Na(v)1.4 channel blockers
    Antonio Carrieri
    Dipartimento Farmaco Chimico, Universita degli Studi di Bari, Via Orabona 4, 70125 Bari, Italy
    Eur J Med Chem 44:1477-85. 2009
  10. ncbi request reprint Binding models of reversible inhibitors to type-B monoamine oxidase
    Antonio Carrieri
    Dipartimento Farmaco Chimico, Universita di Bari, Via Orabona 4, 70125 Bari, Italy
    J Comput Aided Mol Des 16:769-78. 2002

Detail Information

Publications10

  1. doi request reprint Molecular determinants for nuclear receptors selectivity: chemometric analysis, dockings and site-directed mutagenesis of dual peroxisome proliferator-activated receptors α/γ agonists
    Antonio Carrieri
    Dipartimento di Farmacia Scienze del Farmaco, Università degli Studi di Bari Aldo Moro, Via E Orabona 4, 70125 Bari, Italy
    Eur J Med Chem 63:321-32. 2013
    ..Computational results suggested site directed mutagenesis experiments which confirmed the importance of amino acid residues in PPAR activity, allowing the identification of critical hotspots most likely taking over PPARs selectivity...
  2. ncbi request reprint Recent trends and future prospects in computational GPCR drug discovery: from virtual screening to polypharmacology
    Antonio Carrieri
    Dipartimento di Farmacia Scienze del Farmaco, Università degli Studi di Bari Aldo Moro Via Orabona 4, 70125 Bari, Italy
    Curr Top Med Chem 13:1069-97. 2013
    ..Here, we discuss some of the advantages of multi-target approaches, and we review some significant examples of their application in the last decade to that well known class of pharmaceutical targets, the G-protein coupled receptors...
  3. doi request reprint In vitro effectiveness of anidulafungin against Candida sp. biofilms
    Antonio Rosato
    Dipartimento di Farmacia Scienze del Farmaco, Università degli Studi di Bari Aldo Moro, Via Orabona 4, Bari Italy
    J Antibiot (Tokyo) 66:701-4. 2013
    ..albicans and C. tropicalis biofilms...
  4. ncbi request reprint N-aryl-2,6-dimethylbenzamides, a new generation of tocainide analogues as blockers of skeletal muscle voltage-gated sodium channels
    Marilena Muraglia
    Dipartimento di Farmacia Scienze del Farmaco, Sezione di Farmacologia, Università degli Studi di Bari Aldo Moro, Via E Orabona n 4, 70126 Bari, Italy
    J Med Chem 57:2589-600. 2014
    ....
  5. ncbi request reprint A convenient synthesis of lubeluzole and its enantiomer: evaluation as chemosensitizing agents on human ovarian adenocarcinoma and lung carcinoma cells
    Maria Maddalena Cavalluzzi
    Dipartimento di Farmacia Scienze del Farmaco, Università degli Studi di Bari Aldo Moro, Via E Orabona 4, 70126 Bari, Italy
    Bioorg Med Chem Lett 23:4820-3. 2013
    ..005-5 μM), the lowest limit being at least 40 times lower than human plasma concentrations previously reported as causing serious side effects...
  6. doi request reprint Structure-activity relationships in 1,4-benzodioxan-related compounds. 10. Novel α1-adrenoreceptor antagonists related to openphendioxan: synthesis, biological evaluation, and α1d computational study
    Antonio Carrieri
    Dipartimento Farmaco Chimico, Universita di Bari, Via Orabona 4, 70125 Bari, Italy
    Bioorg Med Chem 18:7065-77. 2010
    ....
  7. ncbi request reprint Biological profiling of anti-HIV agents and insight into CCR5 antagonist binding using in silico techniques
    Antonio Carrieri
    Dipartimento Farmaco Chimico, Universita degli Studi di Bari, Via Orabona 4, 70125 Bari, Italy
    ChemMedChem 4:1153-63. 2009
    ..These results are compared with shape- and property-based virtual screening results for commercially available entry blockers, and will be valuable for predicting new HIV entry-blocking leads...
  8. doi request reprint 2-Aminobenzothiazole derivatives: search for new antifungal agents
    Alessia Catalano
    Dipartimento di Farmacia Scienze del Farmaco, Università degli Studi di Bari Aldo Moro, Via E Orabona n 4, 70125 Bari, Italy
    Eur J Med Chem 64:357-64. 2013
    ..None of the two compounds did show any cytotoxicity effect on human THP-1 cells...
  9. ncbi request reprint 2D- and 3D-QSAR of tocainide and mexiletine analogues acting as Na(v)1.4 channel blockers
    Antonio Carrieri
    Dipartimento Farmaco Chimico, Universita degli Studi di Bari, Via Orabona 4, 70125 Bari, Italy
    Eur J Med Chem 44:1477-85. 2009
    ..QSAR and pharmacophore models were then used to support at 3D level this hypothesis...
  10. ncbi request reprint Binding models of reversible inhibitors to type-B monoamine oxidase
    Antonio Carrieri
    Dipartimento Farmaco Chimico, Universita di Bari, Via Orabona 4, 70125 Bari, Italy
    J Comput Aided Mol Des 16:769-78. 2002
    ..A significant trend of correlation was observed between estimated energies of the complexes and the experimental inhibition data...